betaine and creatine

betaine has been researched along with creatine in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199011 (26.83)18.7374
1990's1 (2.44)18.2507
2000's6 (14.63)29.6817
2010's17 (41.46)24.3611
2020's6 (14.63)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K1
Balschi, JA; Blumenfeld, JD; Brenner, RM; Gullans, SR; Hebert, SC; Heilig, CW; Kaleta, M1
Gottschalk, G; Hippe, H; Möller, B1
Chalmers, RA; Hind, AJ; Iles, RA1
Fuller, HL; Keshavarz, K2
Hathcock, JN; Scott, ML1
Menkès, G1
Barker, GJ; Bell, JD; Brenner, RE; Hawkins, CP; Landon, DN; McDonald, WI; Munro, PM; Williams, SC1
Bakalli, RI; Chamruspollert, M; Pesti, GM1
Bell, JD; Chung, YL; Hurley, M; Scott, DL; Wassif, WS1
HARPER, HA; HIGGINS, AR; JONES, RE; KIMMEL, JR; KLINE, EF; MERRILL, RS; SMITH, TW1
BORSOOK, H; BORSOOK, ME2
GRAYBIEL, A; PATTERSON, CA1
Bell, JD; Chung, YL; Hicks, J; Miller, FW; Passo, MH; Rennebohm, RM; Rider, LG; Scott, DL; Summers, RM; Zemel, LS1
Li, JX; Xu, ZR; Zhan, XA; Zhao, RQ1
Allen, RH; Brosnan, JT; Brosnan, ME; Jacobs, RL; Mudd, SH; Stabler, SP; Vance, DE; Wagner, C1
Agbaje, IM; Amigues, E; Browne, RA; Green, BD; Hollis, J; Mallidis, C; McClure, N; Migaud, M; Rogers, D1
Artioli, G; Barroso, R; Costa, A; da Costa Leite, C; del Favero, S; Gualano, B; Lancha-Junior, AH; Negrelli, AL; Otaduy, MC; Roschel, H; Tricoli, V; Ugrinowitsch, C1
Bach Knudsen, KE; Bertram, HC; Westerhuis, JA; Yde, CC1
Bertolo, RF; McBreairty, LE2
Atzori, L; Fanos, V; Lanari, M; Lazzarotto, T; Locci, E; Manzoni, P; Noto, A1
Galloway, MP; Ghoddoussi, F; Hall, CS; Perrine, SA; Sajja, VS; VandeVord, PJ1
Cholewa, JM; Guimarães-Ferreira, L; Zanchi, NE1
Alahakoon, AU; Jayasena, DD; Jo, C; Jung, S; Kim, HJ; Kim, SH; Lee, JH1
Hu, C; Huang, X; Lin, X; Niu, J; Tan, Y; Wang, H; Wang, X; Yin, P; Zeng, J; Zhou, L1
Caudill, MA; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Malysheva, O; Parvez, F; Shahriar, H; Siddique, AB; Uddin, MN1
Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL1
Charismiadou, M; Deligeorgis, SG; Fotakis, C; Goliomytis, M; Lantzouraki, DZ; Simitzis, PE; Zoumpoulakis, P1
Almeida, S; Alves, MG; Barros, A; Carvalho, RA; Jarak, I; Oliveira, PF; Sousa, M1
Erickson, JL; Harty, PS; Jagim, AR; Kerksick, CM; Molling, PE; Zabriskie, HA1
Crego, AL; Kammeijer, GSM; Marina, ML; Mayboroda, OA; Peters, DJM; Ramautar, R; Sánchez-López, E1
Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Slavkovich, V; Uddin, MN1
Elango, R1
Cadogan, DJ; Chrystal, PV; Inhuber, V; McGilchrist, P; Moss, AF; Sharma, NK; Wilkinson, SJ1
Andjic, MM; Bolevich, S; Draginic, ND; Jakovljevic, VLJ; Jeremic, JN; Milinkovic, MV; Pantovic, SB; Prokic, VZ; Rankovic, MR; Sretenovic, JZ; Zivkovic, VI1
Guyader, J; Jiang, Q; Loor, JJ; Pan, YX; Sherlock, DN; Zhang, H1
Hua, Y; Huang, W; Jing, Z; Li, J; Wang, F; Wang, Q; Zhao, Y1

Reviews

5 review(s) available for betaine and creatine

ArticleYear
The nutritional burden of methylation reactions.
    Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:1

    Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Creatine; Diet; Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nutritional Status; Phosphatidylcholines

2013
Effects of betaine on performance and body composition: a review of recent findings and potential mechanisms.
    Amino acids, 2014, Volume: 46, Issue:8

    Topics: Adiposity; Athletic Performance; Betaine; Biological Availability; Body Composition; Creatine; Dietary Supplements; Exercise; Growth Hormone; Humans; Insulin-Like Growth Factor I; Lipogenesis; Lipolysis; Muscle, Skeletal; Physical Endurance; Protein Biosynthesis; Receptor, Insulin

2014
The dynamics of methionine supply and demand during early development.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2016, Volume: 41, Issue:6

    Topics: Betaine; Child Development; Choline; Creatine; Diet; Dietary Supplements; DNA Methylation; Folic Acid; Humans; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Methionine; Phosphatidylcholines

2016
Multi-ingredient pre-workout supplements, safety implications, and performance outcomes: a brief review.
    Journal of the International Society of Sports Nutrition, 2018, Aug-08, Volume: 15, Issue:1

    Topics: Amino Acids; Athletes; Athletic Performance; beta-Alanine; Betaine; Caffeine; Creatine; Dietary Supplements; Humans; Muscle Strength; Performance-Enhancing Substances; Physical Endurance; Sports Nutritional Physiological Phenomena

2018
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur

2020

Trials

5 trial(s) available for betaine and creatine

ArticleYear
Effects of methionine and betaine supplementation on growth performance, carcase composition and metabolism of lipids in male broilers.
    British poultry science, 2006, Volume: 47, Issue:5

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Betaine; Body Composition; Carnitine; Chickens; Creatine; Diet; Dietary Supplements; Fatty Acids; Lipid Metabolism; Liver; Male; Methionine; Muscle, Skeletal; Sterol Esterase; Weight Gain

2006
Creatine but not betaine supplementation increases muscle phosphorylcreatine content and strength performance.
    Amino acids, 2012, Volume: 42, Issue:6

    Topics: Adolescent; Adult; Betaine; Body Composition; Creatine; Dietary Supplements; Double-Blind Method; Humans; Magnetic Resonance Spectroscopy; Male; Muscle Strength; Muscle, Skeletal; Phosphocreatine; Placebos

2012
Supplementation with Folic Acid, but Not Creatine, Increases Plasma Betaine, Decreases Plasma Dimethylglycine, and Prevents a Decrease in Plasma Choline in Arsenic-Exposed Bangladeshi Adults.
    The Journal of nutrition, 2016, Volume: 146, Issue:5

    Topics: Adult; Arsenic; Bangladesh; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Female; Folic Acid; Humans; Male; Middle Aged; Sarcosine; Tandem Mass Spectrometry; Vitamin B Complex; Young Adult

2016
Betaine and choline status modify the effects of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults.
    European journal of nutrition, 2021, Volume: 60, Issue:4

    Topics: Adult; Arsenic; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Folic Acid; Homocysteine; Humans; Methylation

2021
Guanidinoacetic acid provides superior cardioprotection to its combined use with betaine and (or) creatine in HIIT-trained rats.
    Canadian journal of physiology and pharmacology, 2022, Aug-01, Volume: 100, Issue:8

    Topics: Animals; Betaine; Creatine; Glycine; High-Intensity Interval Training; Hydrogen Peroxide; Male; Rats; Rats, Wistar

2022

Other Studies

31 other study(ies) available for betaine and creatine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
    Bioorganic & medicinal chemistry, 2011, Nov-01, Volume: 19, Issue:21

    Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters

2011
Accumulation of major organic osmolytes in rat renal inner medulla in dehydration.
    The American journal of physiology, 1988, Volume: 255, Issue:4 Pt 2

    Topics: Animals; Betaine; Creatine; Dehydration; Glycerylphosphorylcholine; Inositol; Kidney Medulla; Lactates; Magnetic Resonance Spectroscopy; Osmolar Concentration; Proteins; Rats; Rats, Inbred WKY; Reference Values

1988
Degradation of various amine compounds by mesophilic clostridia.
    Archives of microbiology, 1986, Volume: 145, Issue:1

    Topics: Amines; Betaine; Choline; Clostridium; Creatine; Ethanolamine; Ethanolamines; Hydrogen-Ion Concentration; Species Specificity

1986
Methylmalonic aciduria and propionic acidaemia studied by proton nuclear magnetic resonance spectroscopy.
    Clinica chimica acta; international journal of clinical chemistry, 1986, Dec-15, Volume: 161, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Creatine; Female; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Infant; Infant, Newborn; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Malonates; Methylmalonic Acid; Propionates

1986
Relationship of arginine and methionine to creatine formation in chicks.
    The Journal of nutrition, 1971, Volume: 101, Issue:7

    Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Body Weight; Chickens; Choline; Choline Deficiency; Creatine; Cystine; Deficiency Diseases; Depression, Chemical; Folic Acid; Folic Acid Deficiency; Glycine; Glycine max; Guanidines; Lipid Metabolism; Liver; Male; Methionine; Muscles; Ornithine; Stimulation, Chemical; Urea; Vitamin B 12; Vitamin B 12 Deficiency; Zea mays

1971
Relationship of arginine and methionine in the nutrition of the chick and the significance of creatine biosynthesis in their interaction.
    The Journal of nutrition, 1971, Volume: 101, Issue:2

    Topics: Aminobutyrates; Animal Feed; Animals; Arginine; Betaine; Chickens; Creatine; Diet; Drug Antagonism; Drug Synergism; Glycine; Lysine; Methionine; Muscles; Nutritional Physiological Phenomena; Pyridoxine

1971
Alterations of methionine to cysteine conversion rates and nutritional muscular dystrophy in chicks.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 121, Issue:3

    Topics: Animals; Betaine; Choline; Creatine; Cysteine; Guanidines; Methionine; Muscular Dystrophies; Poultry; Vitamin E Deficiency

1966
[The "reequilibration" test and its use in the treatment of certain forms of cancer and other afflictions].
    Journal of chromatography, 1966, Volume: 25, Issue:1

    Topics: Adenosine Triphosphate; Asparagine; Betaine; Choline; Creatine; Cysteine; Deficiency Diseases; Electrophoresis; Elements; Glutamates; Histidine; Humans; Metabolic Diseases; Methionine; Neoplasms; Quaternary Ammonium Compounds

1966
The proton NMR spectrum in acute EAE: the significance of the change in the Cho:Cr ratio.
    Magnetic resonance in medicine, 1993, Volume: 29, Issue:6

    Topics: Animals; Betaine; Brain; Choline; Chromatography, High Pressure Liquid; Creatine; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Magnetic Resonance Spectroscopy; Microscopy, Electron; Phosphocreatine; Phosphorylcholine

1993
The influence of labile dietary methyl donors on the arginine requirement of young broiler chicks.
    Poultry science, 2002, Volume: 81, Issue:8

    Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Chickens; Creatine; Diet; Eating; Female; Male; Methionine; Methylation; Muscle, Skeletal; Nutritional Requirements; Weight Gain

2002
Urinary levels of creatine and other metabolites in the assessment of polymyositis and dermatomyositis.
    Rheumatology (Oxford, England), 2003, Volume: 42, Issue:2

    Topics: Adult; Aged; Betaine; Biomarkers; Choline; Citric Acid; Creatine; Dermatomyositis; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Muscle, Skeletal; Polymyositis

2003
Effects of creatine precursors in arthritis; clinical and metabolic study of glycocyamine and betaine.
    California medicine, 1952, Volume: 77, Issue:1

    Topics: Arthritis; Betaine; Creatine; Female; Glycine; Humans

1952
The biochemical basis of betaine-glycocyamine therapy.
    Annals of western medicine and surgery, 1951, Volume: 5, Issue:10

    Topics: Betaine; Biochemical Phenomena; Cardiovascular Diseases; Creatine; Glycine; Humans

1951
Treatment of cardiac decompensation with betaine and glycocyamine.
    Annals of western medicine and surgery, 1951, Volume: 5, Issue:10

    Topics: Betaine; Biochemical Phenomena; Cardiovascular Diseases; Creatine; Glycine; Heart Failure; Humans

1951
Use of betaine and glycocyamine in the treatment of patients with heart disease: preliminary report.
    Annals of western medicine and surgery, 1951, Volume: 5, Issue:10

    Topics: Betaine; Cardiovascular Diseases; Creatine; Glycine; Heart Diseases; Humans

1951
Muscle metabolites, detected in urine by proton spectroscopy, correlate with disease damage in juvenile idiopathic inflammatory myopathies.
    Arthritis and rheumatism, 2005, Aug-15, Volume: 53, Issue:4

    Topics: Adolescent; Betaine; Biomarkers; Child; Child, Preschool; Choline; Creatine; Female; Glycine; Humans; Magnetic Resonance Spectroscopy; Male; Methylamines; Muscles; Myositis

2005
Methyl balance and transmethylation fluxes in humans.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:1

    Topics: Animals; Betaine; Creatine; Diet; Guanidinoacetate N-Methyltransferase; Humans; Kinetics; Liver; Methylation; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine

2007
Metabolic profile changes in the testes of mice with streptozotocin-induced type 1 diabetes mellitus.
    International journal of andrology, 2009, Volume: 32, Issue:2

    Topics: Animals; Betaine; Carnitine; Choline; Creatine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fertility; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Principal Component Analysis; Spermatogenesis; Testis

2009
Application of NMR-based metabonomics suggests a relationship between betaine absorption and elevated creatine plasma concentrations in catheterised sows.
    The British journal of nutrition, 2012, Volume: 107, Issue:11

    Topics: Animals; Betaine; Biomarkers; Catheters, Indwelling; Creatine; Cross-Over Studies; Dietary Fiber; Female; Intestinal Absorption; Intestine, Small; Magnetic Resonance Spectroscopy; Mesenteric Arteries; Metabolomics; Methionine; Portal Vein; Solubility; Sus scrofa; Time Factors

2012
Urinary metabolomics in newborns infected by human cytomegalovirus: a preliminary investigation.
    Early human development, 2013, Volume: 89 Suppl 1

    Topics: 3-Hydroxybutyric Acid; Adult; Aminoisobutyric Acids; Betaine; Creatine; Cytomegalovirus; Cytomegalovirus Infections; Discriminant Analysis; Female; Glycine; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Inositol; Magnetic Resonance Spectroscopy; Metabolomics; Pregnancy; Pregnancy Complications, Infectious; Taurine

2013
Blast neurotrauma impairs working memory and disrupts prefrontal myo-inositol levels in rats.
    Molecular and cellular neurosciences, 2014, Volume: 59

    Topics: Animals; Betaine; Blast Injuries; Brain Injuries; Creatine; Ethanolamines; gamma-Aminobutyric Acid; Glutamic Acid; Glycerylphosphorylcholine; Inositol; Lactic Acid; Male; Memory, Short-Term; Pattern Recognition, Physiological; Prefrontal Cortex; Rats; Rats, Sprague-Dawley

2014
Endogenous functional compounds in Korean native chicken meat are dependent on sex, thermal processing and meat cut.
    Journal of the science of food and agriculture, 2015, Mar-15, Volume: 95, Issue:4

    Topics: Animals; Animals, Inbred Strains; Anserine; Antioxidants; Betaine; Carnitine; Carnosine; Chickens; Cooking; Creatine; Female; Hindlimb; Hot Temperature; Male; Meat; Meat-Packing Industry; Muscle, Skeletal; Republic of Korea; Sex Characteristics; Thorax

2015
Metabolomics Identifies Biomarker Pattern for Early Diagnosis of Hepatocellular Carcinoma: from Diethylnitrosamine Treated Rats to Patients.
    Scientific reports, 2015, Nov-03, Volume: 5

    Topics: alpha-Fetoproteins; Animals; Betaine; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cohort Studies; Creatine; Diethylnitrosamine; Disease Models, Animal; Early Diagnosis; Female; Humans; Liver Neoplasms; Male; Metabolomics; Multivariate Analysis; Rats; Rats, Sprague-Dawley

2015
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
    The Journal of nutritional biochemistry, 2016, Volume: 35

    Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium

2016
NMR Metabolomics Investigates the Influence of Flavonoid-Enriched Rations on Chicken Plasma.
    Journal of AOAC International, 2017, Mar-01, Volume: 100, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetic Acid; Alanine; Animal Feed; Animals; Anti-Inflammatory Agents; Antioxidants; Betaine; Chickens; Citric Acid; Creatine; Dietary Supplements; Flavanones; Glycine; Hesperidin; Lipoproteins; Metabolomics; Poultry; Succinic Acid; Vitamin E

2017
Senescence and declining reproductive potential: Insight into molecular mechanisms through testicular metabolomics.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:10

    Topics: Aging; Animals; Betaine; Creatine; Fertility; Glutathione; Magnetic Resonance Spectroscopy; Male; Metabolic Networks and Pathways; Metabolomics; Rats; Rats, Wistar; Testis

2018
Sheathless CE-MS based metabolic profiling of kidney tissue section samples from a mouse model of Polycystic Kidney Disease.
    Scientific reports, 2019, 01-28, Volume: 9, Issue:1

    Topics: Animals; Betaine; Carnitine; Creatine; Creatinine; Disease Models, Animal; Electrophoresis, Capillary; Glutamine; Kidney; Mass Spectrometry; Metabolomics; Mice; Multivariate Analysis; Polycystic Kidney Diseases

2019
Guanidinoacetic acid as a partial replacement to arginine with or without betaine in broilers offered moderately low crude protein diets.
    Poultry science, 2022, Volume: 101, Issue:4

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Chickens; Creatine; Diet; Diet, Protein-Restricted; Dietary Supplements; Glycine; Male; Weight Gain

2022
One-carbon metabolism and related pathways in ruminal and small intestinal epithelium of lactating dairy cows.
    Journal of animal science, 2023, Jan-03, Volume: 101

    Topics: Amino Acids; Animals; Antioxidants; Betaine; Carbon; Cattle; Creatine; Diet; Duodenum; Female; Folic Acid; Glutathione; Intestinal Mucosa; Lactation; Methionine; Milk; Rumen

2023
Metabolites, gene expression, and gut microbiota profiles suggest the putative mechanisms via which dietary creatine increases the serum taurine and g-ABA contents in Megalobrama amblycephala.
    Fish physiology and biochemistry, 2023, Volume: 49, Issue:2

    Topics: Animal Feed; Animals; Betaine; Carbohydrates; Creatine; Creatine Kinase; Cypriniformes; Diet; Dietary Supplements; Gastrointestinal Microbiome; Gene Expression; Taurine

2023