betaine and acetaminophen

betaine has been researched along with acetaminophen in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's7 (77.78)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Anilkumar, N; Brandes, RP; Brewer, AC; Burr, S; Caldwell, A; Dew, T; Dong, X; Halket, J; Hughes, RD; Martin, D; Mistry, RK; Murray, TV; Quaglia, A; Sawyer, GJ; Schröder, K; Shah, AM; Sherwood, R1
Kalantari, H; Khodayar, MJ; Khorsandi, L; Rashno, M; Zeidooni, L2
Berdot, S; Danchin, N; Durieux, P; Pannier, B; Perrin, G; Sabatier, B; Thomas, F1

Reviews

1 review(s) available for betaine and acetaminophen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for betaine and acetaminophen

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice.
    Free radical biology & medicine, 2015, Volume: 89

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Betaine; Blotting, Western; Cells, Cultured; Cysteine; Female; Glutathione; Hep G2 Cells; Homocysteine; Humans; Immunoenzyme Techniques; Liver; Liver Diseases; Methionine; Mice; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; S-Adenosylmethionine

2015
Betaine protects mice against acetaminophen hepatotoxicity possibly via mitochondrial complex II and glutathione availability.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 103

    Topics: Acetaminophen; Animals; Betaine; Catalase; Chemical and Drug Induced Liver Injury; Electron Transport Complex II; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mice; Mitochondria, Liver; Models, Biological; Protective Agents; Reactive Oxygen Species; Superoxide Dismutase

2018
Evaluation of exposure to effervescent drugs in a large health check-up population in France: a cross-sectional study.
    BMJ open, 2018, 07-30, Volume: 8, Issue:7

    Topics: Acetaminophen; Adult; Antipyretics; Aspirin; Betaine; Body Mass Index; Cross-Sectional Studies; Depression; Diet, Sodium-Restricted; Excipients; Female; France; Gastrointestinal Agents; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Self Medication; Sex Factors; Sodium; Sodium Chloride, Dietary; Tablets; Vitamins

2018
Upregulation of Nrf2-related cytoprotective genes expression by acetaminophen-induced acute hepatotoxicity in mice and the protective role of betaine.
    Human & experimental toxicology, 2020, Volume: 39, Issue:7

    Topics: Acetaminophen; Alanine Transaminase; Analgesics; Animals; Aspartate Aminotransferases; Betaine; Chemical and Drug Induced Liver Injury; Gene Expression; Glutathione; Heme Oxygenase-1; Liver; Male; Malondialdehyde; Membrane Proteins; Mice; NF-E2-Related Factor 2; Protective Agents; Up-Regulation

2020