betadex and roxatidine-acetate

betadex has been researched along with roxatidine-acetate* in 2 studies

Other Studies

2 other study(ies) available for betadex and roxatidine-acetate

ArticleYear
Investigation of the binding of roxatidine acetate hydrochloride with cyclomaltoheptaose (β-cyclodextrin) using IR and NMR spectroscopy.
    Carbohydrate research, 2011, Sep-27, Volume: 346, Issue:13

    NMR chemical shift changes of the cyclomaltoheptaose (β-cyclodextrin, β-CD) cavity protons as well as roxatidine acetate hydrochloride aromatic ring protons revealed the formation of a RAH-β-CD inclusion complex. Detailed FTIR and NMR spectroscopic ((1)H NMR, COSY, NOESY, ROESY) studies have been done. The stoichiometry of the complex was determined to be 1:1, and the overall binding constant was also determined by Scott's method. The NOESY spectrum confirmed the selective penetration of the aromatic ring of RAH into the β-CD cavity in comparison to that of the piperidine ring. The mode of penetration of the guest into the CD cavity and structure of the complex has been established.

    Topics: beta-Cyclodextrins; Magnetic Resonance Spectroscopy; Molecular Structure; Piperidines; Spectroscopy, Fourier Transform Infrared

2011
Complexation of roxatidine acetate hydrochloride with beta-cyclodextrin: NMR spectroscopic study.
    Die Pharmazie, 2004, Volume: 59, Issue:8

    A NMR spectroscopic study of mixtures of varying ratios of roxatidine acetate hydrochloride (RAH) and beta-cyclodextrin (beta-CD) in D2O revealed the formation of a 1:1 inclusion compound. The aromatic ring of RAH selectively penetrates the beta-CD cavity in preference to the piperidine ring.

    Topics: Anti-Ulcer Agents; beta-Cyclodextrins; Cyclodextrins; Deuterium Oxide; Excipients; Magnetic Resonance Spectroscopy; Piperidines

2004
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