betadex and ferrous-sulfate

All kinds of soil conditioners have been used to improve soil quality. The application of many traditional soil conditioners was limited by single performance. In this study, a novel multifunctional microspheric soil conditioner was prepared based on Arabic gum, gelatin, chitosan and β-cyclodextrin. Arabic gum and gelatin (AG-GL) microspheric carriers, which could load ferrous sulfate (FS), were synthesized via complex coagulation method. The AG-GL(FS) microspheres were covered by chitosan quaternary ammonium salt (CQAS) through single coagulation method. And β-cyclodextrin (β-CD) was used as the outermost shell to improve chemical stability of the soil conditioner by saturated solution method. Finally, the novel multifunctional microspheric soil conditioner AG-GL/CQAS/β-CD-FS was obtained and characterized by Fourier transform infrared spectroscopy, thermogravimetric analyzer, polarizing microscope, scanning electron microscope and particle size analyzer. The novel soil conditioner shows good nutrient slowly-releasing, water retention, heavy metal ions adsorption and antibacterial performances with the particle size of 14-17 μm and high thermal decomposition temperature, which has the potential application in improving soil quality.

Topics: Adsorption; beta-Cyclodextrins; Chitosan; Ferrous Compounds; Gelatin; Gum Arabic; Microspheres; Particle Size; Quaternary Ammonium Compounds; Salts; Soil; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

Many diseases are associated with the overproduction of hydroperoxides that inflict cell damage. A novel cyclodextrin derivative, 6A,6B-diseleninic acid-6A',6B'-selenium bridged beta-cyclodextrin (6-diSeCD), was synthesized to be a functional mimic of glutathione peroxidase (GPX) that normally removes these hydroperoxides. The mimic had high catalytic GPX activity of 13.5 U/micromol, which is 13.6-fold higher than ebselen (PZ51), and was chemically and biologically stable in vitro. Antioxidant activity was studied by ferrous sulfate/ascorbate-induced mitochondria damage model system. These data show that the mimic has great antioxidant activity. Such mimics may result in better clinical therapies for diseases mediated by hydroperoxides.

Topics: Animals; Antioxidants; Ascorbic Acid; beta-Cyclodextrins; Cattle; Cyclodextrins; Ferrous Compounds; Glutathione; Mitochondria; Models, Biological; Organoselenium Compounds; Oxidation-Reduction; Reactive Oxygen Species; Selenium Compounds