betadex and carbendazim

Topics: Benzimidazoles; beta-Cyclodextrins; Carbamates; Electrochemical Techniques; Electrodes; Humans; Limit of Detection; Malus; Nanotubes, Carbon; Reproducibility of Results

Considering the importance of developing a new analytical approach for pesticide residue detection for the sake of ensuring food safety, a β-cyclodextrin based molecularly imprinted polymer was prepared for selective determination of carbendazim. The polymers consist of a porous and hollow structure demonstrating the selective abundant adsorption sites for carbendazim molecule. The selectivity and adsorption capacity of the imprinted polymers were analyzed with dispersive solid-phase extraction and analyzed with high performance liquid chromatography coupled with ultraviolet. The results of imprinted polymers were higher than non-imprinted polymers with the maximum adsorption capacity of 3.65 mg/g within 30 min of total adsorption time. The reusability of the imprinted polymers was determined to evaluate its effectiveness and stability, which proved that the polymers lost 10% efficiency within seven consecutive recycles. The developed method displayed good linearity over the concentration range of 0.05-2.0 mg/L. The recovery percentage of 81.33-97.23 with relative standard deviations of 1.49-4.66% was obtained from spiked apple, banana, orange, and peach samples with a limit of detection of 0.03 mg/L and a limit of quantification of 0.10 mg/L (signal to noise ratio = 3/10). The overall performance of the proposed method evident that this technique provided a desirable outcome and it can be used as a convenient approach, as it qualifies the analytical standards.

Topics: Adsorption; Benzimidazoles; beta-Cyclodextrins; Carbamates; Chromatography, High Pressure Liquid; Fruit; Fungicides, Industrial; Molecular Imprinting; Molecular Structure; Particle Size; Polymers; Solid Phase Extraction; Surface Properties; Ultraviolet Rays

The β-cyclodextrin-acrylamide (CDM-AM) copolymer was prepared from acrylamide and β-CD maleate (CDM) using K2S2O8 as initiator. The effects of the CDM-AM copolymer on the solubility and fungicidal activity of natamycin (NM) and carbendazim (MBC) were investigated. The stability constant of NM·CDM-AM and MBC·CDM-AM complexes at 303 K were of 10,725.45 M(-1) and 3000.89 M(-1), respectively. The complexes were characterized using phase solubility diagrams, NMR spectra and FT-IR spectra. The analysis of the biological activities of these two complexes indicated that they possessed enhancing fungicidal activities compared to NM and MBC alone.

Topics: Acrylamide; Antifungal Agents; Aspergillus niger; Benzimidazoles; beta-Cyclodextrins; Carbamates; Natamycin; Polymers

The effect of hydroxypropyl-β-cyclodextrin (HPβCD) on the improvement of the solubility and fungicidal activity of carbendazim (MBC) has been investigated. The inclusion complexation of HPβCD with MBC has been prepared and characterized by phase solubility diagram, fluorescence, (1)H NMR, ROESY and FT-IR spectra. The stoichiometric ratio and stability constant were determined by Job's plot and phase solubility studies, respectively. The inclusion complex MBC·HPβCD has exhibited different properties from MBC. The obtained inclusion complex was found to significantly improve the water solubility of MBC. In addition, the biological activity indicated that the complex displayed the better fungicidal activity than MBC. The present study provided useful information for a more rational application of MBC.

Topics: 2-Hydroxypropyl-beta-cyclodextrin; Benzimidazoles; beta-Cyclodextrins; Carbamates; Fungicides, Industrial; Magnetic Resonance Spectroscopy; Solubility; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Trichoderma