betadex has been researched along with 4-bromobenzenesulfonamide* in 1 studies
1 other study(ies) available for betadex and 4-bromobenzenesulfonamide
Article | Year |
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Combining NMR and molecular modelling in a drug delivery context: investigation of the multi-mode inclusion of a new NPY-5 antagonist bromobenzenesulfonamide into beta-cyclodextrin.
NMR spectroscopic and molecular modelling methods have been employed to describe the complexation of trans-N-4-[N'-(4-chlorobenzoyl)hydrazinocarbonyl]cyclohexylmethyl-4-bromobenzenesulfonamide, a new chemotype of NPY-5 antagonist, and beta-cyclodextrin, revealing the coexistence of two different kinds of 1:1 complexes where conformational changes of the guest compound with respect to the free state are also detected. Topics: beta-Cyclodextrins; Biochemistry; Bromobenzenes; Cyclodextrins; Cyclohexanes; Drug Carriers; Drug Evaluation, Preclinical; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Receptors, Neuropeptide Y; Stereoisomerism; Sulfonamides | 2004 |