betadex and 4-bromobenzenesulfonamide

betadex has been researched along with 4-bromobenzenesulfonamide* in 1 studies

Other Studies

1 other study(ies) available for betadex and 4-bromobenzenesulfonamide

ArticleYear
Combining NMR and molecular modelling in a drug delivery context: investigation of the multi-mode inclusion of a new NPY-5 antagonist bromobenzenesulfonamide into beta-cyclodextrin.
    Bioorganic & medicinal chemistry, 2004, Jan-15, Volume: 12, Issue:2

    NMR spectroscopic and molecular modelling methods have been employed to describe the complexation of trans-N-4-[N'-(4-chlorobenzoyl)hydrazinocarbonyl]cyclohexylmethyl-4-bromobenzenesulfonamide, a new chemotype of NPY-5 antagonist, and beta-cyclodextrin, revealing the coexistence of two different kinds of 1:1 complexes where conformational changes of the guest compound with respect to the free state are also detected.

    Topics: beta-Cyclodextrins; Biochemistry; Bromobenzenes; Cyclodextrins; Cyclohexanes; Drug Carriers; Drug Evaluation, Preclinical; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Receptors, Neuropeptide Y; Stereoisomerism; Sulfonamides

2004