beta-nitrostyrene and diethyl-malonate

beta-nitrostyrene has been researched along with diethyl-malonate* in 1 studies

Other Studies

1 other study(ies) available for beta-nitrostyrene and diethyl-malonate

ArticleYear
Transition state analysis of an enantioselective Michael addition by a bifunctional thiourea organocatalyst.
    Organic & biomolecular chemistry, 2019, 04-17, Volume: 17, Issue:16

    The mechanism of the enantioselective Michael addition of diethyl malonate to trans-β-nitrostyrene catalyzed by a tertiary amine thiourea organocatalyst is explored using experimental 13C kinetic isotope effects and density functional theory calculations. Large primary 13C KIEs on the bond-forming carbon atoms of both reactants suggest that carbon-carbon bond formation is the rate-determining step in the catalytic cycle. This work resolves conflicting mechanistic pictures that have emerged from prior experimental and computational studies.

    Topics: Catalysis; Density Functional Theory; Malonates; Molecular Structure; Stereoisomerism; Styrenes; Thiourea

2019