beta-naphthoflavone and triazoles

beta-naphthoflavone has been researched along with triazoles in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's9 (64.29)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bend, JR; Knickle, LC2
Bend, JR; Woodcroft, KJ1
Mackie, JE; Marks, GS; Massey, TE; Riddick, DS1
Matsubara, T; Touchi, A; Yamada, N1
Bend, JR; Dostal, LA; Mathews, JM1
Matsubara, T; Nishiyama, S; Touchi, A; Yamada, N1
Bend, JR; Knickle, LC; Philpot, RM1
Bend, JR; House, AA; Knickle, LC; Webb, CD1
Bend, JR; Falkner, KC; Horton, JE; McCallum, GP1
Bend, JR; Mathews, JM1
Carlile, DJ; Hakooz, N; Houston, JB1
Hu, YZ; Yao, TW2

Other Studies

14 other study(ies) available for beta-naphthoflavone and triazoles

ArticleYear
Dose-dependent, mechanism-based inactivation of cytochrome P450 monooxygenases in vivo by 1-aminobenzotriazole in liver, lung, and kidney of untreated, phenobarbital-treated, and beta-naphthoflavone-treated guinea pigs.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:12

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Isoenzymes; Kidney; Liver; Lung; Male; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Triazoles

1992
N-aralkylated derivatives of 1-aminobenzotriazole as isozyme-selective, mechanism-based inhibitors of guinea pig hepatic cytochrome P-450 dependent monooxygenase activity.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:9

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Isoenzymes; Kinetics; Liver; Male; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Triazoles

1990
3,5-Diethoxycarbonyl-2,6-dimethyl-4-ethyl-1,4-dihydropyridine inactivates rat liver cytochrome P-450c, but not its orthologue, rabbit lung form 6.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Dicarbethoxydihydrocollidine; Dihydropyridines; Heme; In Vitro Techniques; Isoenzymes; Liver; Lung; Male; Microsomes; Rabbits; Rats; Species Specificity; Triazoles

1990
Effect of change of hepatic drug-metabolizing activity on plasma concentrations of major metabolites of the new sleep inducer 450191-S, a 1H-1,2,4-triazolyl benzophenone derivative.
    Japanese journal of pharmacology, 1987, Volume: 44, Issue:4

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Enzyme Induction; Hypnotics and Sedatives; Liver; Male; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Triazoles

1987
Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Isoenzymes; Lung; Male; Microsomes; NADP; Oxidoreductases; Oxidoreductases, N-Demethylating; Oxygenases; Perfusion; Rabbits; Stereoisomerism; Triazoles

1985
[Effect of a new sleep inducer, 1H-1,2,4-triazolyl benzophenone derivative 450191-S on rat liver drug-metabolizing enzyme system].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:2

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Drug Interactions; Hypnotics and Sedatives; Liver; Male; Microsomes, Liver; Nitrazepam; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains; Triazoles

1985
Bioactivation of arachidonic acid by the cytochrome P450 monooxygenases of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for formation of epoxyeicosatrienoic acids.
    Molecular pharmacology, 1994, Volume: 45, Issue:6

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Guinea Pigs; Lung; Male; Metyrapone; Microsomes; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Triazoles

1994
N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Guinea Pigs; Isoenzymes; Liver; Lung; Male; Phenobarbital; Sensitivity and Specificity; Triazoles

1994
Mechanism-based inactivation of cytochrome P450 1A1 by N-aralkyl-1-aminobenzotriazoles in guinea pig kidney in vivo and in vitro: minimal effects on metabolism of arachidonic acid by renal P450-dependent monooxygenases.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Animals; Arachidonic Acid; Benzoflavones; beta-Naphthoflavone; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Guinea Pigs; Kidney; Male; Microsomes; Microsomes, Liver; Oxidoreductases; Oxygenases; Triazoles

1993
Microsomal cytochrome P450 1A1 dependent monooxygenase activity in guinea pig heart: induction, inhibition, and increased activity by addition of exogenous NADPH-cytochrome P450 reductase.
    Canadian journal of physiology and pharmacology, 1993, Volume: 71, Issue:2

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Induction; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; Male; Microsomes; Myocardium; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Oxygenases; Triazoles

1993
N-aralkyl derivatives of 1-aminobenzotriazole as potent isozyme-selective mechanism-based inhibitors of rabbit pulmonary cytochrome P450 in vivo.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Isoenzymes; Lung; Male; Microsomes, Liver; Pentobarbital; Rabbits; Substrate Specificity; Triazoles

1993
Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated with known modifiers of cytochrome P-450 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:4

    Topics: Animals; beta-Naphthoflavone; Cell Separation; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley; Triazoles

1999
In vitro metabolism and inductive or inhibitive effect of DL111 on rat cytochrome P4501A enzyme.
    Chemico-biological interactions, 2004, Mar-15, Volume: 147, Issue:2

    Topics: Abortifacient Agents, Nonsteroidal; Animals; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Dexamethasone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Induction; Enzyme Inhibitors; Female; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley; Triazoles

2004
Induction of diphenytriazol on cytochrome CYP1A.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Aminopyrine; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Female; Fluvoxamine; Microsomes, Liver; Phenacetin; Rats; Rats, Sprague-Dawley; Triazoles

2004