beta-naphthoflavone and pregnenolone carbonitrile

beta-naphthoflavone has been researched along with pregnenolone carbonitrile in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199012 (50.00)18.7374
1990's6 (25.00)18.2507
2000's5 (20.83)29.6817
2010's1 (4.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choudhuri, S; Guo, GL; Klaassen, CD1
Nakanishi, S; Nishiguchi, K; Serasinghe, P; Serasinghe, S; Yamazaki, H1
Koliada, AIu1
Gram, TE; Okine, LK1
Juchau, MR; Namkung, MJ; Nelson, SD; Porubek, DJ1
Balfour, C; Dunbar, D; Halpert, J; Kaminsky, LS; Miller, NE; Morgan, ET1
Davis, M; Smith, HM; Tredger, JM; Williams, R1
Bradshaw, JJ; Ivanetich, KM1
Dannan, GA; Guengerich, FP; Kaminsky, LS1
Davis, M; Powell-Jackson, PR; Smith, HM; Tredger, JM; Williams, R1
Batt, AM; Martin, N; Siest, G1
Steggles, AW; Vlasuk, GP; Walz, FG1
Duvivier, J; Gielen, JE; Van Cantfort, J1
Porter, WR; Trager, WF; Wheeler, C1
Cresteil, T; Gonzalez, FJ; Kersual, J; Marie, S; Sonnier, M1
Kharasch, ED; Thummel, KE1
Amacher, DE; Schomaker, SJ1
Carmichael, N; Debruyne, E; Lassere, D; Nicod, L; Richert, L; Viollon-Abadie, C1
Evans, DC; McAllister, G; Meneses-Lorente, G; Surry, DD1
Handschin, C; Hoffmann, K; Meyer, UA; Podvinec, M; Stöckli, J1
Lake, BG; Meredith, C; Price, RJ; Renwick, AB; Scott, MP1
Danz, M; Lupp, A; Müller, D1
Etzrodt, J; Glöckner, R; Lupp, A; Müller, D1
Smith, EM; Wilson, JY1

Other Studies

24 other study(ies) available for beta-naphthoflavone and pregnenolone carbonitrile

ArticleYear
Induction profile of rat organic anion transporting polypeptide 2 (oatp2) by prototypical drug-metabolizing enzyme inducers that activate gene expression through ligand-activated transcription factor pathways.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:1

    Topics: Animals; Blotting, Northern; DNA Probes; Enzyme Induction; Gene Expression Regulation, Enzymologic; Ligands; Liver; Liver-Specific Organic Anion Transporter 1; Male; Membranes; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors; Transcription, Genetic

2002
Intralobular localization of different cytochrome P-450 form dependent monooxygenase activities in the liver of normal and inducer-treated rats.
    The International journal of biochemistry, 1992, Volume: 24, Issue:6

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Induction; Liver; Male; Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains

1992
[Cytochrome P-450 isoforms in the liver of rats treated with phenobarbital, 3-methylcholanthrene and Aroclor 1254 studied by monoclonal antibodies].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Clone Cells; Cytochrome P-450 Enzyme System; Imidazoles; Immunization; Isoenzymes; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains

1986
In vitro studies on the metabolism and covalent binding of [14C]1,1-dichloroethylene by mouse liver, kidney and lung.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dichloroethylenes; Enzyme Induction; Glutathione; Hot Temperature; Hydrocarbons, Chlorinated; In Vitro Techniques; Kidney; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; NADP; Phenobarbital; Piperonyl Butoxide; Pregnenolone Carbonitrile; Proadifen; Subcellular Fractions

1986
Regulation of aromatic oxidation of estradiol-17 beta in maternal hepatic, fetal hepatic and placental tissues: comparative effects of a series of inducing agents.
    Journal of steroid biochemistry, 1985, Volume: 22, Issue:4

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP1A1; Estradiol; Ethanol; Female; Liver; Male; Methylcholanthrene; Phenobarbital; Placenta; Polychlorinated Dibenzodioxins; Pregnancy; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid Hydroxylases

1985
Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo.
    Molecular pharmacology, 1985, Volume: 28, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chloramphenicol; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid 16-alpha-Hydroxylase; Substrate Specificity; Testosterone; Warfarin

1985
Use of a direct high performance liquid chromatography method for multiple testosterone hydroxylations in studies of microsomal monooxygenase activities.
    Biochemical pharmacology, 1984, Jun-01, Volume: 33, Issue:11

    Topics: Acetanilides; Aldrin; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Cricetinae; Cytochrome P-450 Enzyme System; Ethylmorphine; Male; Mesocricetus; Microsomes, Liver; Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rifampin; Testosterone

1984
Isoflurane: a comparison of its metabolism by human and rat hepatic cytochrome P-450.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:9

    Topics: Adult; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Female; Fluorine; Humans; In Vitro Techniques; Isoflurane; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Pregnenolone Carbonitrile; Rats; Species Specificity

1984
Composition of cytochrome P-450 isozymes from hepatic microsomes of C57BL/6 and DBA/2 mice assessed by warfarin metabolism, immunoinhibition, and immunoelectrophoresis with anti-(rat cytochrome P-450).
    European journal of biochemistry, 1984, May-15, Volume: 141, Issue:1

    Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Catalysis; Cytochrome P-450 Enzyme System; Enzyme Induction; Immunochemistry; Immunoelectrophoresis; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Stereoisomerism; Warfarin

1984
Effect of rifampicin on the mouse hepatic mixed-function oxidase system.
    Biochemical pharmacology, 1981, May-15, Volume: 30, Issue:10

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rifampin; Sodium Fluoride

1981
Induction of group-1 and group-2 UDP-glucuronosyltransferase in microsomes from the livers of C57 Bl/6 mice.
    Toxicology letters, 1981, Volume: 9, Issue:4

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Enzyme Induction; Glucuronosyltransferase; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Safrole; Substrate Specificity

1981
Species differences in cytochromes P-450 and epoxide hydrolase: comparisons of xenobiotic-induced hepatic microsomal polypeptides in hamsters and rats.
    Biochemistry, 1983, Mar-29, Volume: 22, Issue:7

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Induction; Epoxide Hydrolases; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Species Specificity; Stilbenes

1983
The influence of five monoxygenase inducers on liver cytosol estradiol receptor levels in the ovariectomized adult rat.
    Biochemical and biophysical research communications, 1981, Mar-16, Volume: 99, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Castration; Cytosol; Enzyme Induction; Female; Liver; Methylcholanthrene; Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Receptors, Estradiol; Receptors, Estrogen

1981
Changes in the metabolic profiles of R- and S-warfarin and R- and S-phenprocoumon as a probe to categorize the effect of inducing agents on microsomal hydroxylases.
    Biochemical pharmacology, 1981, Nov-15, Volume: 30, Issue:22

    Topics: 4-Hydroxycoumarins; Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenprocoumon; Polychlorinated Dibenzodioxins; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Stereoisomerism; Warfarin

1981
Evidence for the transient expression of P-450 during the neonatal period in rat.
    Biochimica et biophysica acta, 1994, Sep-21, Volume: 1208, Issue:1

    Topics: Amino Acid Sequence; Animals; Animals, Newborn; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Female; Kidney; Liver; Lung; Male; Microsomes, Liver; Molecular Sequence Data; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley

1994
Human alfentanil metabolism by cytochrome P450 3A3/4. An explanation for the interindividual variability in alfentanil clearance?
    Anesthesia and analgesia, 1993, Volume: 76, Issue:5

    Topics: Alfentanil; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Liver; Male; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Pyrazoles; Rats; Rats, Sprague-Dawley

1993
Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes.
    Toxicology letters, 1998, Jan-31, Volume: 94, Issue:2

    Topics: Animals; Antibodies; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Biomarkers; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Ethylmorphine-N-Demethylase; Female; Isoniazid; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Sex Factors

1998
Phenobarbital, beta-naphthoflavone, clofibrate, and pregnenolone-16alpha-carbonitrile do not affect hepatic thyroid hormone UDP-glucuronosyl transferase activity, and thyroid gland function in mice.
    Toxicology and applied pharmacology, 1999, Feb-15, Volume: 155, Issue:1

    Topics: Animals; beta-Naphthoflavone; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronosyltransferase; Liver; Male; Mice; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyroid Hormones

1999
High throughput ribonuclease protection assay for the determination of CYP3A mRNA induction in cultured rat hepatocytes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Cells, Cultured; Clofenapate; Cloning, Molecular; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Activation; Enzyme Inhibitors; Female; In Situ Hybridization; Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Ribonucleases; RNA Probes; RNA, Messenger; Tetrazolium Salts; Toxicity Tests

1999
Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:9

    Topics: Animals; Avian Proteins; beta-Naphthoflavone; Cell Line; Chickens; Clotrimazole; Colforsin; Constitutive Androstane Receptor; Cyclic AMP; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Glutethimide; Growth Inhibitors; Hormone Antagonists; Humans; Metyrapone; Mifepristone; Okadaic Acid; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Binding; Pyridines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Signal Transduction; Trans-Activators; Transcription Factors

2001
Studies on the induction of rat hepatic CYP1A, CYP2B, CYP3A and CYP4A subfamily form mRNAs in vivo and in vitro using precision-cut rat liver slices.
    Xenobiotica; the fate of foreign compounds in biological systems, 2003, Volume: 33, Issue:5

    Topics: Animals; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Clofenapate; Culture Techniques; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Primers; Enzyme Induction; Isoenzymes; Liver; Male; Oligonucleotide Probes; Organ Size; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; RNA, Messenger

2003
Histomorphological changes and cytochrome P450 isoforms expression and activities in precision-cut liver slices from neonatal rats.
    Toxicology, 2005, Jan-31, Volume: 206, Issue:3

    Topics: Animals; Animals, Newborn; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Female; Hepatocytes; Histocytochemistry; Isoenzymes; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats

2005
Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility.
    Analytical and bioanalytical chemistry, 2008, Volume: 392, Issue:6

    Topics: Aging; Animals; Anti-Inflammatory Agents; beta-Naphthoflavone; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enzyme Induction; Enzyme Inhibitors; Hydroxylation; Liver; Male; Mixed Function Oxygenases; Organ Culture Techniques; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Testosterone; Time Factors

2008
Assessment of cytochrome P450 fluorometric substrates with rainbow trout and killifish exposed to dexamethasone, pregnenolone-16alpha-carbonitrile, rifampicin, and beta-naphthoflavone.
    Aquatic toxicology (Amsterdam, Netherlands), 2010, May-10, Volume: 97, Issue:4

    Topics: Animals; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Fundulidae; Liver; Male; Microsomes, Liver; Oncorhynchus mykiss; Pregnenolone Carbonitrile; Rifampin; Statistics, Nonparametric

2010