beta-naphthoflavone has been researched along with benzo(a)pyrene in 94 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (35.11) | 18.7374 |
| 1990's | 20 (21.28) | 18.2507 |
| 2000's | 27 (28.72) | 29.6817 |
| 2010's | 13 (13.83) | 24.3611 |
| 2020's | 1 (1.06) | 2.80 |
| Authors | Studies |
|---|---|
| Gonda, H; Katayama, Y; Kuroki, S; Murata, M; Suzutani, T; Yano, K | 1 |
| Fujita, Y; Hashimoto, Y; Ishikawa, M; Noguchi-Yachide, T; Tetsuhashi, M; Yonehara, M | 1 |
| Novikov, KN; Sumbalova, Z; Timofeev, KN | 1 |
| Jimenez, B; Oikari, A | 1 |
| Castro-Maderal, L; Sullivan, PD | 1 |
| Eriksson, LC; Ritter, E | 1 |
| Garg, A; Gupta, RC; Krca, S; Kurelec, B | 1 |
| Barton, HA; Costantini, MG; Forkert, PG; Marletta, MA | 1 |
| Kent, C; Paulson, BK; Porter, TJ | 1 |
| Goertz, MP; Jongen, WM; Sandker, GW; Topp, RJ; van Bladeren, PJ | 1 |
| Fujita, S; Masubuchi, Y; Matsunaga, T; Suzuki, T | 1 |
| Foth, H; Kahl, GF; Kahl, R; Mollière, M | 1 |
| Francis, JE; Smith, AG | 1 |
| Kao, LR; Wilkinson, CF | 1 |
| Topp, RJ; van Bladeren, PJ | 1 |
| Bücker, M; Glatt, H; Oesch, F; Platt, KL | 1 |
| Gurtoo, HL; Koser, P; Raina, V | 1 |
| DeLor, DK; Sonnenfeld, G | 1 |
| Shertzer, HG; Skelly, MF | 2 |
| Karis, MA; Menzel, DB; Williams, SJ | 1 |
| Crespi, CL; Thilly, WG | 1 |
| Fujino, T; Gelboin, HV; Guengerich, FP; Park, SS; West, D | 1 |
| Buhler, DR; Williams, DE | 1 |
| Mason, ME; Okey, AB | 1 |
| Anderson, MW; Boroujerd, M; Kung, HC; Wilson, AG | 1 |
| Wang, IY | 1 |
| Alexandrov, K; Dansette, PM; Frayssinet, C; Markovits, P; Rouet, P | 1 |
| Malejka-Giganti, D; Ritter, CL | 1 |
| Gelboin, HV; Gozukara, EM; Guengerich, FP; Miller, H | 1 |
| Lau, PP; Lu, AY; Pickett, CB; Strobel, HW | 1 |
| Fouts, JR; Pohl, RJ | 1 |
| Abdel-Tawab, GA; El-Bassiouni, EA; El-Sebae, AH; El-Sewedy, SM; El-Zoghby, SM; Mostafa, MH; Ramadan, M | 1 |
| Atuma, S; Blanck, A; Hällstöm, I | 1 |
| Decker, RW; Malejka-Giganti, D; Ritter, CL | 1 |
| Gurtoo, HL; Raina, V; Williams, CJ | 1 |
| Shertzer, HG | 1 |
| Anderson, LM; Budinger, JM; Deschner, EE; Priest, LJ | 1 |
| Halpert, J; Jergil, B; Schelin, C; Wallin, H | 1 |
| Davis, M; Smith, HM; Tredger, JM; Williams, R | 1 |
| Acebo, AL; Alworth, WL; Gan, LS | 1 |
| Montague, W; Otaiba, A; Raza, H | 1 |
| Bracken, W; Bullock, P; Draper, A; Parkinson, A; Pearce, R; Podval, J; Thomas, P; Veltman, J | 1 |
| Kupfer, D; Lee, CA; Mani, C; Rifkind, AB | 1 |
| Agarwal, SC; Jackson, L; Lambert, GR; Nesnow, S; Padgett, WT | 1 |
| Leff, T; Rosenberg, DW | 1 |
| Callander, RD; Clay, P; Elcombe, CR; Elliott, BM; Mackay, JM | 1 |
| Galloway, SM; Johnson, TE; Umbenhauer, DR | 1 |
| Arai, H; Degawa, M; Hashimoto, Y; Matsuda, K | 1 |
| Altman, AH; James, MO; Kleinow, KM; Morris, K; Tong, Z | 1 |
| Pacheco, M; Santos, MA | 2 |
| Di Giulio, RT; King, LC; Kohan, MJ; Ploch, SA | 1 |
| Rauch, P; Schimmer, O | 1 |
| Fung, J; Iba, MM; Thomas, PE | 1 |
| Miller, CA | 1 |
| Brauze, D; Malejka-Giganti, D | 1 |
| Annas, A; Brittebo, E; Hellman, B | 1 |
| Davis, C; Lambert, G; Nelson, GB; Nesnow, S; Padgett, WT; Ross, JA; Yacopucci, M | 1 |
| Brandt, I; Brunström, B; Granberg, AL | 1 |
| Auyeung, DJ; Kessler, FK; Ritter, JK | 1 |
| Doi, AM; Holmes, E; Kleinow, KM | 1 |
| Gravato, C; Santos, MA | 1 |
| Correia, AC; Maria, VL; Santos, MA | 1 |
| Bonacci, S; Chiea, R; Corsi, I; Focardi, S; Regoli, F | 1 |
| Myers, S; Robertson, LW; Tampal, N | 1 |
| Lake, BG; Meredith, C; Price, RJ; Renwick, AB; Scott, MP | 1 |
| Hiramatsu, N; Kasai, A; Kitamura, M; Maeda, S; Meng, Y; Takeda, M; Yao, J | 1 |
| El-Kadi, AO; Elbekai, RH; Gharavi, N; Korashy, HM; Wills, K | 1 |
| Hiramatsu, N; Kasai, A; Kitamura, M; Maeda, S; Meng, Y; Yao, J | 1 |
| Hayakawa, K; Hiramatsu, N; Kasai, A; Kitamura, M; Shitamura, A; Yao, J | 1 |
| Garric, J; Geffard, O; Noury, P; Tutundjian, R | 1 |
| Beaton, D; Chen, S; Nguyen, N; Operaña, TN; Tukey, RH | 1 |
| Gesto, M; Míguez, JM; Soengas, JL; Tintos, A | 2 |
| Ahel, M; Calić, V; Grubesić, MS; Krca, S; Smital, T; Terzić, S; Zaja, R | 1 |
| Lee, ME; Urso, P | 1 |
| Gesto, M; Míguez, JM; Soengas, JL | 1 |
| Gagnon, MM; Rose, T; Webb, D | 1 |
| Brandt, I; Brunström, B; Jönsson, ME | 1 |
| Gesto, M; Míguez, JM; Rodríguez-Illamola, A; Soengas, JL; Tintos, A | 1 |
| Hashimoto, H; Ichikawa, M; Iwano, S; Miyamoto, Y; Takizawa, S | 1 |
| Cheng, YW; Hsu, YJ; Hsu, YT; Kang, JJ; Li, CH; Liao, PL | 1 |
| Fardel, O; Lagadic-Gossmann, D; Le Ferrec, E; Mayati, A | 1 |
| Dias Bainy, AC; Kalb, AC; Monserrat, JM; Ribas Ferreira, JL; Stacke Ferreira, R; Stegeman, J; Zanette, J | 1 |
| Brinkmann, J; Fritsche, E; Genkinger, D; Henkler, F; Hutzler, C; Luch, A; Salzmann, S; Stolpmann, K; Wajant, H | 1 |
| Brauze, D; Rawłuszko, AA | 1 |
| Au, DW; Hwang, DS; Jung, JH; Kim, BM; Kim, RO; Lee, JS; Leung, KM; Rhee, JS; Shim, WJ; Wu, RS | 1 |
| Arlt, VM; Frei, E; Hodek, P; Kizek, R; Koblihová, J; Stiborová, M | 1 |
| Carletti, M; Girolami, F; Manzini, L; Nebbia, C; Spalenza, V | 1 |
| Mahiout, S; Pohjanvirta, R | 1 |
| Kim, H; Kim, J; Lee, YM; Won, EJ; Yim, B | 1 |
| Bednarek, K; Brauze, D; Giefing, M; Grenman, R; Janiszewska, J; Jarmuz-Szymczak, M; Kiwerska, K | 1 |
| Woo, SJ | 1 |
94 other study(ies) available for beta-naphthoflavone and benzo(a)pyrene
| Article | Year |
|---|---|
An electrochemical device for the assay of the interaction between a dioxin receptor and its various ligands.
Topics: beta-Naphthoflavone; Electrochemistry; HeLa Cells; Humans; Ligands; Protein Binding; Receptors, Aryl Hydrocarbon | 2004 |
beta-Naphthoflavone analogs as potent and soluble aryl hydrocarbon receptor agonists: improvement of solubility by disruption of molecular planarity.
Topics: beta-Naphthoflavone; Cell Line, Tumor; Humans; Receptors, Aryl Hydrocarbon; Solubility; Structure-Activity Relationship | 2010 |
[The effect of lysolecithin on rat liver microsome monooxygenase activity after induction by xenobiotics of the methylcholanthrene type].
Topics: Animals; Anisoles; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Coumarins; Enzyme Induction; Hydroxylation; Intracellular Membranes; Lysophosphatidylcholines; Male; Methylation; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Polychlorinated Biphenyls; Rats; Substrate Specificity | 1992 |
Effects of hepatotoxicants on the induction of microsomal monooxygenase activity in sunfish liver by beta-naphthoflavone and benzo[a]pyrene.
Topics: Alanine Transaminase; Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carbon Tetrachloride; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Formic Acid Esters; Glutathione Transferase; L-Lactate Dehydrogenase; Liver; Male; Microsomes, Liver; Oxidoreductases; Oxygenases; Perciformes | 1992 |
Proton NMR study of the interaction of benzo(a)pyrene with rat liver microsomal cytochrome P-450.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1992 |
Kinetics of induction of cytosolic benzaldehyde: NADP and propionaldehyde: NAD aldehyde dehydrogenase activities in rat livers from male Wistar rats.
Topics: 2-Acetylaminofluorene; Aldehyde Dehydrogenase; Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Cytochromes b5; Cytosol; Enzyme Induction; Glutathione Transferase; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains | 1991 |
The potential of carp to bioactivate benzo[a]pyrene to metabolites that bind to DNA.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrene Hydroxylase; beta-Naphthoflavone; Biotransformation; Carps; DNA; DNA Damage; Liver | 1991 |
The 4S polycyclic aromatic hydrocarbon-binding protein: immunohistochemical localization in mice.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Carrier Proteins; Cytochrome P-450 Enzyme System; Cytosol; Glycine N-Methyltransferase; Immunoenzyme Techniques; Kidney; Kinetics; Liver; Lung; Male; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Polycyclic Compounds; Safrole | 1990 |
The effect of polycyclic aromatic hydrocarbons on choline kinase activity in mouse hepatoma cells.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Choline Kinase; Dimethyl Sulfoxide; Enzyme Induction; Liver Neoplasms, Experimental; Mice; Phosphotransferases; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Receptors, Cell Surface; Tumor Cells, Cultured | 1989 |
Modulating effects of beta-naphthoflavone on the induction of SCEs by model compounds with emphasis on benzo[a]pyrene.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cells, Cultured; Chickens; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Liver; Methylcholanthrene; Microsomes, Liver; Sister Chromatid Exchange | 1988 |
Possible mechanism of Sudan III-induced prevention of chemical carcinogenesis in rats.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Azo Compounds; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Enzyme Induction; Glutathione; Liver; Male; Mutagens; Rats; Rats, Inbred Strains; Uridine Diphosphate Glucuronic Acid | 1988 |
Metabolism of benzo[a]pyrene in the combined rat liver--lung perfusion system.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Interactions; Injections, Intraperitoneal; Liver; Lung; Male; Rats; Rats, Inbred Strains; Tissue Distribution | 1987 |
Polycyclic aromatic hydrocarbons cause hepatic porphyria in iron-loaded C57BL/10 mice: comparison of uroporphyrinogen decarboxylase inhibition with induction of alkoxyphenoxazone dealkylations.
Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Iron; Male; Mice; Mice, Inbred C57BL; Oxidoreductases; Phenobarbital; Polycyclic Compounds; Porphyrias; Safrole; Uroporphyrinogen Decarboxylase | 1987 |
Inhibition of cytochrome P-450c-mediated benzo[a]pyrene hydroxylase and ethoxyresorufin O-deethylase by dihydrosafrole.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrene Hydroxylase; beta-Naphthoflavone; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dioxoles; Enzyme Induction; Imidazoles; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; NADP; Oxazines; Oxidoreductases; Rats; Rats, Inbred Strains; Safrole | 1987 |
Oxidative biotransformation in primary cultures of chick embryo hepatocytes: induction of cytochrome P-450 and the metabolism of benzo(a)pyrene.
Topics: Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Chick Embryo; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Liver; Oxidoreductases; Phenobarbital; Porphyrins | 1986 |
Host-mediated mutagenicity experiments with benzo[a]pyrene and two of its metabolites.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Male; Mice; Mutagenicity Tests; Mutation; Salmonella typhimurium | 1985 |
Differential sensitivity of Ah-responsive mice to beta-naphthoflavone-induced metabolism and mutagenesis of benzo[a]pyrene and aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Drug Interactions; Female; Flavonoids; Mice; Mice, Inbred C57BL; Microsomes, Liver | 1985 |
Studies on activation of benzo[a]pyrene for inhibition of interferon induction.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cell Survival; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Glutathione; Interferon Type I; Mice; Mice, Inbred Strains | 1985 |
Differences in pulmonary metabolism of benzo(a)pyrene in inbred mouse strains, using the isolated perfused lung.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Biotransformation; In Vitro Techniques; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Perfusion; Species Specificity | 1985 |
Interactions of heavy metals with the pulmonary metabolism of [3H]benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Biotransformation; Cadmium; Cadmium Chloride; Chromatography, High Pressure Liquid; Cobalt; Drug Interactions; Indomethacin; Lung; Male; Metyrapone; Nickel; Rats; Rats, Inbred Strains; Tritium | 1984 |
Assay for gene mutation in a human lymphoblast line, AHH-1, competent for xenobiotic metabolism.
Topics: Aryl Hydrocarbon Hydroxylases; B-Lymphocytes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Cell Line; Cell Survival; Drug Resistance; Humans; Mixed Function Oxygenases; Mutagens; Mutation; Phenotype; Thioguanine | 1984 |
Monoclonal antibodies that inhibit enzyme activity of 3-methylcholanthrene-induced cytochrome P-450.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Binding Sites; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Epitopes; Humans; Hybridomas; Immunization; Methylcholanthrene; Mice; Microsomes, Liver; Phenobarbital; Protein Binding; Rabbits; Rats | 1982 |
Comparative properties of purified cytochrome P-448 from beta-naphthoflavone treated rats and rainbow trout.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrene Hydroxylase; Benzopyrenes; beta-Naphthoflavone; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Epitopes; Flavonoids; Microsomes, Liver; Phenobarbital; Rats; Salmonidae; Species Specificity; Spectrophotometry; Substrate Specificity; Testosterone; Trout | 1983 |
Aryl hydrocarbon hydroxylase activity in mouse, rat, and human mammary tumors.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Breast Neoplasms; Enzyme Induction; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Microsomes; Rats | 1981 |
Inhibition in vivo of the formation of adducts between metabolites of benzo(a)pyrene and DNA by aryl hydrocarbon hydroxylase inducers.
Topics: Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Deoxyribonucleosides; DNA; Enzyme Induction; Female; Liver; Lung; Mice; Polychlorinated Dibenzodioxins | 1981 |
Effects of phenobarbital, 3-methylcholanthrene and beta-naphthoflavone pretreatment on mouse liver microsomal enzymes and on metabolite patterns of benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Flavonoids; In Vitro Techniques; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Phenobarbital; Proteins | 1981 |
Metabolism of benzo[a]pyrene by brain microsomes of fetal and adult rats and mice. Induction by 5,6 benzoflavone, comparison with liver and lung microsomal activities.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Brain; Cytochrome P-450 Enzyme System; Enzyme Induction; Epoxide Hydrolases; Female; Flavonoids; Glutathione Transferase; Lung; Mice; Mice, Inbred C57BL; Microsomes; Microsomes, Liver; Pregnancy; Rats | 1981 |
Mixed function oxidase in the mammary gland and liver microsomes of lactating rats. Effects of 3-methylcholanthrene and beta-naphthoflavone.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Female; Flavonoids; Lactation; Mammary Glands, Animal; Methylcholanthrene; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; Oxidoreductases; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
Different patterns of benzo[a]pyrene metabolism of purified cytochromes P-450 from methylcholanthrene, beta-naphthoflavone and phenobarbital treated rats.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Inactivation, Metabolic; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1982 |
Comparison of cytochromes P-450 with high activity toward benzo[a]pyrene purified from liver microsomes of beta-naphthoflavone and 3-methylcholanthrene-pretreated rats.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carbon Monoxide; Carcinogens; Cytochrome P-450 Enzyme System; Dithionite; Flavonoids; Immunodiffusion; Immunoelectrophoresis; Male; Methylcholanthrene; Microsomes, Liver; Rats; Substrate Specificity | 1982 |
Cytochrome P-450-dependent xenobiotic metabolizing activity in Zymbal's gland, a specialized sebaceous gland of rodents.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Coumarins; Cytochrome P-450 Enzyme System; Male; Mice; Mice, Hairless; Microsomes; Oxygenases; Rats; Rats, Inbred Strains; Sebaceous Glands | 1983 |
Effect of some xenobiotics on kynurenine hydrolase and kynurenine aminotransferase of mouse liver.
Topics: Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinogens; Chlorodiphenyl (54% Chlorine); Chlorpromazine; Female; Hydrolases; Liver; Lyases; Methylcholanthrene; Mice; Phenobarbital; Pyrazoles; Transaminases | 1983 |
Comparison of cytochrome P-450-dependent metabolism in different developmental stages of Drosophila melanogaster.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Drosophila melanogaster; Kinetics; Larva; Microsomes; Mutagens; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Spectrophotometry | 1983 |
Modifications of carcinogen metabolism in hepatic microsomes of suckling young by 3-methylcholanthrene or beta-naphthoflavone administered to lactating rats.
Topics: 2-Acetylaminofluorene; Animal Population Groups; Animals; Animals, Suckling; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Female; Flavonoids; Hydroxylation; Lactation; Methylcholanthrene; Microsomes, Liver; Pregnancy; Rats | 1983 |
Genetic expression of aflatoxin metabolism. Effects of 3-methylcholanthrene and beta-naphthoflavone on hepatic microsomal metabolism and mutagenic activation of aflatoxins.
Topics: Aflatoxins; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene Expression Regulation; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Microsomes, Liver; Mixed Function Oxygenases; Mutagenicity Tests; Salmonella typhimurium | 1983 |
Indole-3-carbinol protects against covalent binding of benzo[a]pyrene and N-nitrosodimethylamine metabolites to mouse liver macromolecules.
Topics: Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Dimethylnitrosamine; DNA; Indoles; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; Phenobarbital; Rats | 1984 |
Benzo(a)pyrene metabolism in the isolated perfused mouse lung.
Topics: Aniline Compounds; Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; In Vitro Techniques; Lung; Male; Mice; Mice, Inbred ICR; Perfusion | 1983 |
Carcinogenic effects of intracolonic benzo[a]pyrene in beta-naphthoflavone-induced mice.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Colon; Colonic Neoplasms; Female; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mixed Function Oxygenases | 1983 |
Covalent binding of benzo[a]pyrene to cytochrome P-450 beta NF-B2 and other proteins in reconstituted mixed-function oxidase systems.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Enzyme Induction; Epoxide Hydrolases; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Protein Binding; Proteins; Rats; Rats, Inbred Strains | 1984 |
Use of a direct high performance liquid chromatography method for multiple testosterone hydroxylations in studies of microsomal monooxygenase activities.
Topics: Acetanilides; Aldrin; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Cricetinae; Cytochrome P-450 Enzyme System; Ethylmorphine; Male; Mesocricetus; Microsomes, Liver; Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rifampin; Testosterone | 1984 |
1-Ethynylpyrene, a suicide inhibitor of cytochrome P-450 dependent benzo[a]pyrene hydroxylase activity in liver microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrene Hydroxylase; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Kinetics; Male; Microsomes, Liver; NADP; Phenobarbital; Pyrenes; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence | 1984 |
beta-Naphthoflavone-inducible cytochrome P4501A1 activity in liver microsomes of the marine safi fish (Siganus canaliculatus).
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Chromatography, High Pressure Liquid; Cross Reactions; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Fishes; Isoenzymes; Male; Microsomes, Liver; Polycyclic Compounds; Rats; Rats, Wistar | 1995 |
Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.
Topics: Alkylation; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Caffeine; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Cytochromes b5; Dexamethasone; Enzyme Induction; Female; Hydroxylation; Isoenzymes; Macaca fascicularis; Male; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxazines; Oxidation-Reduction; Phenobarbital; Sex Factors; Species Specificity; Testosterone | 1995 |
Induction of tamoxifen-4-hydroxylation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), beta-naphthoflavone (beta NF), and phenobarbital (PB) in avian liver: identification of P450 TCDDAA as catalyst of 4-hydroxylation induced by TCDD and beta NF.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Chick Embryo; Chickens; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Induction; Estrogen Antagonists; Female; Humans; Hydroxylation; Immunoglobulin G; Liver; Mesocricetus; Mice; Microsomes, Liver; Models, Biological; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Species Specificity; Tamoxifen | 1994 |
Quantitative analysis of the metabolism of 9,10-dihydrobenzo[a]pyrene by induced rat liver microsomes.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Male; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains | 1993 |
Regulation of cytochrome P450 in cultured human colonic cells.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinoma, Hepatocellular; Colonic Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Kinetics; Liver Neoplasms; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Sprague-Dawley; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Evaluation of phenobarbital/beta-naphthoflavone as an alternative S9-induction regime to Aroclor 1254 in the rat for use in in vitro genotoxicity assays.
Topics: Administration, Oral; Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Chlorodiphenyl (54% Chlorine); Chromosome Aberrations; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Female; Humans; Liver Extracts; Lymphocytes; Male; Mutagenicity Tests; Phenobarbital; Rats; Salmonella typhimurium | 1995 |
Human liver S-9 metabolic activation: proficiency in cytogenetic assays and comparison with phenobarbital/beta-naphthoflavone or aroclor 1254 induced rat S-9.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chlorodiphenyl (54% Chlorine); CHO Cells; Cricetinae; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Induction; Humans; Liver; Mutagenicity Tests; Mutagens; Phenobarbital; Rats | 1996 |
Lead nitrate inhibits the induction of CYP1A mRNAs by aromatic amines but not by aryl hydrocarbons in the rat liver.
Topics: Animals; Base Sequence; Benzo(a)pyrene; beta-Naphthoflavone; Carbolines; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Imidazoles; Male; Methylcholanthrene; Microsomes, Liver; Oligonucleotide Probes; p-Aminoazobenzene; Rats; Rats, Inbred F344; Structure-Activity Relationship | 1996 |
Dietary modulation of phase 1 and phase 2 activities with benzo(a)pyrene and related compounds in the intestine but not the liver of the channel catfish, Ictalurus punctatus.
Topics: Animals; Benzo(a)pyrene; Benzopyrene Hydroxylase; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diet; Enzyme Induction; Epoxide Hydrolases; Female; Ictaluridae; Intestinal Mucosa; Liver; Male | 1997 |
Induction of EROD activity and genotoxic effects by polycyclic aromatic hydrocarbons and resin acids on the juvenile eel (Anguilla anguilla L.).
Topics: Abietanes; Anguilla; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Diterpenes; Enzyme Induction; Enzyme Inhibitors; Erythrocytes; Mutagenicity Tests; Mutagens; Phenanthrenes; Polycyclic Aromatic Hydrocarbons | 1997 |
Comparative in vitro and in vivo benzo[a]pyrene-DNA adduct formation and its relationship to CYP1A activity in two species of ictalurid catfish.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Carcinogens, Environmental; Cytochrome P-450 Enzyme System; DNA Adducts; Ictaluridae; Liver; Microsomes, Liver; Species Specificity | 1998 |
Inhibition of metabolic activation of the promutagens, benzo[a]pyrene, 2-aminofluorene and 2-aminoanthracene by furanochromones in Salmonella typhimurium.
Topics: Animals; Anthracenes; Antimutagenic Agents; Benzo(a)pyrene; beta-Naphthoflavone; Chromans; Cytochrome P-450 Enzyme System; Cytosol; Daunorubicin; Dose-Response Relationship, Drug; Fluorenes; Fruit; Khellin; Male; Mutagens; Plant Extracts; Rats; Rats, Wistar; Salmonella typhimurium | 1998 |
Cytochrome P450 1A1 in rat peripheral blood lymphocytes: inducibility in vivo and bioactivation of benzo[a]pyrene in the Salmonella typhimurium mutagenicity assay in vitro.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Blotting, Western; Bromobenzenes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dexamethasone; Enzyme Induction; Lymphocytes; Male; Methylcholanthrene; Mutagenicity Tests; Mutagens; Pyridines; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Smoking | 1999 |
A human aryl hydrocarbon receptor signaling pathway constructed in yeast displays additive responses to ligand mixtures.
Topics: Aryl Hydrocarbon Receptor Nuclear Translocator; Base Sequence; Benzo(a)pyrene; beta-Galactosidase; beta-Naphthoflavone; Binding Sites; DNA-Binding Proteins; Drug Synergism; Genes, Reporter; Genetic Engineering; Hexachlorobenzene; Humans; Ligands; Molecular Sequence Data; Plasmids; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Saccharomyces cerevisiae; Signal Transduction; Transcription Factors | 1999 |
A novel 4 S [3H]beta-naphthoflavone-binding protein in liver cytosol of female Sprague-Dawley rats treated with aryl hydrocarbon receptor agonists.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzofurans; beta-Naphthoflavone; Binding, Competitive; Carrier Proteins; Cytochrome P-450 CYP1A1; Cytosol; Female; Glycine N-Methyltransferase; Kinetics; Liver; Methylcholanthrene; Methyltransferases; Molecular Weight; Polychlorinated Dibenzodioxins; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon | 2000 |
Evaluation of benzo(a)pyrene-induced DNA damage in human endothelial cells using alkaline single cell gel electrophoresis.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens, Environmental; Cell Line; Comet Assay; Cytochrome P-450 CYP1A1; DNA Damage; Endothelium, Vascular; Female; Humans; Infant, Newborn; Mice; Mice, Inbred C57BL; Mutagens | 2000 |
Biotransformation of trans-4,5-dihydroxy-4,5-dihydrobenzo[a]pyrene to benzo[a]pyrene bis-diols and DNA adducts by induced rat liver microsomes.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Biotransformation; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; Male; Microsomes, Liver; Nuclear Magnetic Resonance, Biomolecular; Rats; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Stereoisomerism | 2000 |
Cytochrome P450-dependent binding of 7,12-dimethylbenz[a]anthracene (DMBA) and benzo[a]pyrene (B[a]P) in murine heart, lung, and liver endothelial cells.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Autoradiography; Benz(a)Anthracenes; Benzo(a)pyrene; beta-Naphthoflavone; Carcinogens; Coronary Vessels; Cytochrome P-450 CYP1A1; Ellipticines; Endothelium, Vascular; Environmental Pollutants; Enzyme Induction; Female; In Vitro Techniques; Liver; Lung; Mice; Polychlorinated Biphenyls; Tissue Distribution | 2000 |
Tissue distribution and temperature-dependence of Anguilla anguilla L. EROD activity following exposure to model inducers and relationship with plasma cortisol, lactate and glucose levels.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Blood Glucose; Cytochrome P-450 CYP1A1; Environmental Exposure; Fishes; Hydrocortisone; Lactic Acid; Temperature; Water Pollutants, Chemical | 2001 |
An alternative promoter contributes to tissue- and inducer-specific expression of the rat UDP-glucuronosyltransferase 1A6 gene.
Topics: 5' Untranslated Regions; Animals; Base Sequence; Benzo(a)pyrene; beta-Naphthoflavone; Digestive System; DNA, Complementary; Exons; Gene Expression; Glucuronosyltransferase; Humans; Kidney; Liver; Male; Methylcholanthrene; Molecular Sequence Data; Promoter Regions, Genetic; Pyrazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Thiones; Thiophenes | 2001 |
P-glycoprotein in the catfish intestine: inducibility by xenobiotics and functional properties.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzo(a)pyrene; beta-Naphthoflavone; Biological Availability; Biological Transport, Active; Blotting, Western; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Electrophoresis, Polyacrylamide Gel; Ictaluridae; Intestinal Mucosa; Intestines; Liver; Polychlorinated Biphenyls; Vincristine; Xenobiotics | 2001 |
Juvenile sea bass liver P450, EROD induction, and erythrocytic genotoxic responses to PAH and PAH-like compounds.
Topics: Alanine Transaminase; Animals; Bass; Benzo(a)pyrene; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Enzyme Induction; Erythrocytes; Liver; Micronucleus Tests; Naphthalenes; Polycyclic Aromatic Hydrocarbons; Time Factors; Water Pollutants, Chemical | 2002 |
Benzo[a]pyrene and beta-naphthoflavone mutagenic activation by European eel (Anguilla anguilla L.) S9 liver fraction.
Topics: Anguilla; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 CYP1A1; Enzyme Induction; Enzyme Inhibitors; Liver; Mutagens; Water Pollutants, Chemical | 2002 |
Induction of EROD activity in European eel (Anguilla anguilla) experimentally exposed to benzo[a]pyrene and beta-naphthoflavone.
Topics: Anguilla; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Biomarkers; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Environmental Exposure; Enzyme Induction; Enzyme Inhibitors; Water Pollutants, Chemical | 2003 |
Binding of polychlorinated biphenyls/metabolites to hemoglobin.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Biomarkers; Biphenyl Compounds; Erythrocytes; Female; Globins; Hemoglobins; Humans; Mice; Mice, Inbred C57BL; Phenobarbital; Polychlorinated Biphenyls | 2003 |
Use of cultured precision-cut rat lung slices to study the in vitro induction of pulmonary cytochrome P450 forms.
Topics: Animals; Aroclors; Benzo(a)pyrene; beta-Naphthoflavone; Culture Techniques; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Lung; Male; Rats; Tissue Fixation | 2003 |
DRESSA: biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase.
Topics: Alkaline Phosphatase; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Dioxins; Enzyme Induction; Gene Expression Regulation; Liver Neoplasms; Mammary Tumor Virus, Mouse; Methylcholanthrene; Mice; Plasmids; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Response Elements; Sensitivity and Specificity; Transfection; Tumor Cells, Cultured | 2004 |
Benzo[a]pyrene, 3-methylcholanthrene and beta-naphthoflavone induce oxidative stress in hepatoma hepa 1c1c7 Cells by an AHR-dependent pathway.
Topics: Benzo(a)pyrene; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Humans; Hydrogen Peroxide; Ligands; Lipid Peroxidation; Methylcholanthrene; Oxidative Stress; Receptors, Aryl Hydrocarbon; Signal Transduction | 2004 |
Fast-track DRESSA: a bioassay for fast, sensitive, and selective detection of halogenated and polycyclic aromatic hydrocarbons.
Topics: Alkaline Phosphatase; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Cell Line, Tumor; Dioxins; Hydrocarbons, Halogenated; Methylcholanthrene; Mice; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons; Reproducibility of Results; Time Factors | 2005 |
Bioassay-based screening of microorganisms that degrade dioxin using substrate-immobilized microtubes.
Topics: Bacteria; Benzo(a)pyrene; beta-Naphthoflavone; Biodegradation, Environmental; Biological Assay; Culture Media; Dioxins; Hydrocarbons, Aromatic; Polychlorinated Dibenzodioxins; Polypropylenes; Serum Albumin, Bovine; Solvents | 2005 |
Non destructive in vivo measurement of ethoxyresorufin biotransformation by zebrafish prolarva: development and application.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Biological Assay; Biotransformation; Cytochrome P-450 CYP1A1; Environmental Monitoring; Kinetics; Larva; Oxazines; Water Pollution, Chemical; Zebrafish; Zebrafish Proteins | 2006 |
Human CYP1A1GFP expression in transgenic mice serves as a biomarker for environmental toxicant exposure.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Biomarkers; Blotting, Western; Cell Line, Tumor; Cells, Cultured; Cytochrome P-450 CYP1A1; Environmental Monitoring; Environmental Pollutants; Enzyme Induction; Glucuronosyltransferase; Green Fluorescent Proteins; Hepatocytes; Humans; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Recombinant Fusion Proteins; Transcription, Genetic; Transfection | 2007 |
beta-Naphthoflavone and benzo(a)pyrene treatment affect liver intermediary metabolism and plasma cortisol levels in rainbow trout Oncorhynchus mykiss.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Benzo(a)pyrene; beta-Naphthoflavone; Blood Glucose; Estradiol; Female; Fructose-Bisphosphatase; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Hydrocortisone; Lactic Acid; Liver; Oncorhynchus mykiss | 2008 |
Hepatic biomarker responses to organic contaminants in feral chub (Leuciscus cephalus)--laboratory characterization and field study in the Sava River, Croatia.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Bile; Biomarkers; Chromatography, High Pressure Liquid; Croatia; Cyprinidae; Cytochrome P-450 CYP1A1; Environmental Monitoring; Enzyme Activation; Female; Glutathione Transferase; Hydrogen-Ion Concentration; Liver; Male; Polychlorinated Biphenyls; Sensitivity and Specificity; Spectrometry, Fluorescence; Water Pollutants, Chemical | 2007 |
Suppression of T lymphocyte proliferation to antigenic and mitogenic stimuli by Benzo(alpha)pyrene and 2-aminofluorene metabolites.
Topics: Acetyl Coenzyme A; Animals; Antigens; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Cell Proliferation; Cells, Cultured; Concanavalin A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA Adducts; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorenes; Immunosuppressive Agents; Interleukin-2; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred C3H; Mitogens; Spleen; T-Lymphocytes | 2007 |
Acute and prolonged stress responses of brain monoaminergic activity and plasma cortisol levels in rainbow trout are modified by PAHs (naphthalene, beta-naphthoflavone and benzo(a)pyrene) treatment.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Biogenic Monoamines; Blood Glucose; Brain Chemistry; Hydrocortisone; Lactic Acid; Naphthalenes; Oncorhynchus mykiss; Plant Oils; Population Density; Stress, Physiological; Sunflower Oil; Water Pollutants, Chemical | 2008 |
Hepatic metabolism of contaminants in the terapontid fish, yellowtail trumpeter (Amniataba caudavittata Richardson).
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Bile; Cytochrome P-450 CYP1A1; Environmental Monitoring; Fishes; Injections, Intraperitoneal; L-Iditol 2-Dehydrogenase; Liver; Polycyclic Aromatic Hydrocarbons; Rivers; Water Pollutants, Chemical; Western Australia | 2008 |
beta-Naphthoflavone and benzo(a)pyrene alter dopaminergic, noradrenergic, and serotonergic systems in brain and pituitary of rainbow trout (Oncorhynchus mykiss).
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Biogenic Monoamines; Brain; Brain Stem; Dopamine; Female; Hydroxyindoleacetic Acid; Norepinephrine; Oncorhynchus mykiss; Pituitary Gland; Serotonin; Superior Colliculi | 2009 |
The zebrafish gill model: induction of CYP1A, EROD and PAH adduct formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Gene Expression Regulation; Gills; Liver; Polycyclic Aromatic Hydrocarbons; Zebrafish | 2009 |
Effects of naphthalene, beta-naphthoflavone and benzo(a)pyrene on the diurnal and nocturnal indoleamine metabolism and melatonin content in the pineal organ of rainbow trout, Oncorhynchus mykiss.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Circadian Rhythm; Indoles; Melatonin; Naphthalenes; Oncorhynchus mykiss; Pineal Gland; Time Factors; Water Pollutants, Chemical | 2009 |
Identification of AhR-regulated genes involved in PAH-induced immunotoxicity using a highly-sensitive DNA chip, 3D-Gene Human Immunity and Metabolic Syndrome 9k.
Topics: Benzo(a)pyrene; beta-Naphthoflavone; Cell Line; Dose-Response Relationship, Immunologic; Humans; Immunity; Immunosuppressive Agents; Metabolic Syndrome; Mutagens; Oligonucleotide Array Sequence Analysis; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Small Interfering; Time Factors | 2010 |
Benzo[a]pyrene inhibits angiogenic factors-induced alphavbeta3 integrin expression, neovasculogenesis, and angiogenesis in human umbilical vein endothelial cells.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Carcinogens; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Chick Embryo; Chorioallantoic Membrane; Drug Antagonism; Endothelium, Vascular; Enzyme Inhibitors; Gene Silencing; Humans; Integrin alphaVbeta3; Mitogen-Activated Protein Kinases; Neovascularization, Physiologic; Phosphorylation; Umbilical Veins | 2010 |
Aryl hydrocarbon receptor-independent up-regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC-1 cells.
Topics: Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Calcium; Cell Line; Cytochrome P-450 Enzyme System; Endothelial Cells; Environmental Pollution; Gene Knockdown Techniques; Humans; Receptors, Aryl Hydrocarbon; RNA, Small Interfering; Up-Regulation | 2012 |
Biomarkers of organic contamination in the South American fish Poecilia vivipara and Jenynsia multidentata.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Biomarkers; Cyprinodontiformes; Cytochrome P-450 Enzyme System; Fish Proteins; Gene Expression Regulation, Enzymologic; Gills; Liver; Male; South America; Species Specificity; Transcription, Genetic; Water Pollutants, Chemical | 2012 |
Activation of the aryl hydrocarbon receptor sensitises human keratinocytes for CD95L- and TRAIL-induced apoptosis.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Apoptosis; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; beta-Naphthoflavone; Caspase 8; Cell Line; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Adducts; Fas Ligand Protein; Humans; Keratinocytes; Receptors, Aryl Hydrocarbon; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA Interference; RNA, Small Interfering; Signal Transduction | 2012 |
The effect of aryl hydrocarbon receptor ligands on the expression of polymerase (DNA directed) kappa (Polκ), polymerase RNA II (DNA directed) polypeptide A (PolR2a), CYP1B1 and CYP1A1 genes in rat liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA-Directed DNA Polymerase; Environmental Pollutants; Female; Ligands; Liver; Methylcholanthrene; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; RNA Polymerase II; RNA, Messenger | 2012 |
Evaluation of biomarker potential of cytochrome P450 1A (CYP1A) gene in the marine medaka, Oryzias melastigma exposed to water-accommodated fractions (WAFs) of Iranian crude oil.
Topics: Amino Acid Sequence; Animals; Base Sequence; Benzo(a)pyrene; beta-Naphthoflavone; Biomarkers; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Fish Proteins; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Metabolic Detoxication, Phase I; Molecular Sequence Data; Oryzias; Petroleum; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Water Pollutants, Chemical | 2013 |
The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Blotting, Western; Chromatography, Thin Layer; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; DNA Adducts; Environmental Pollutants; Enzyme Activation; Intestine, Small; Isoenzymes; Liver; Male; Microsomes, Liver; Rats; Rats, Wistar | 2013 |
Constitutive expression of the AHR signaling pathway in a bovine mammary epithelial cell line and modulation by dioxin-like PCB and other AHR ligands.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Cattle; Cell Line; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Down-Regulation; Environmental Pollutants; Enzyme Induction; Epithelial Cells; Female; Glutathione Transferase; Isoenzymes; Ligands; Mammary Glands, Animal; Receptors, Aryl Hydrocarbon; Signal Transduction; Time Factors | 2015 |
Aryl hydrocarbon receptor agonists trigger avoidance of novel food in rats.
Topics: Analysis of Variance; Animals; Avoidance Learning; Benzo(a)pyrene; beta-Naphthoflavone; Carbazoles; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Dose-Response Relationship, Drug; Eating; Feeding Behavior; Food Preferences; Male; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; RNA, Messenger; Taste; Time Factors | 2016 |
Identification and molecular characterization of cytochrome P450 (CYP450) family genes in the marine ciliate Euplotes crassus: The effect of benzo[a]pyrene and beta-naphthoflavone.
Topics: Amino Acid Sequence; Aquatic Organisms; Benzo(a)pyrene; beta-Naphthoflavone; Carcinogens, Environmental; Cell Survival; Conserved Sequence; Cytochrome P-450 Enzyme System; Euplotes; Exons; Gene Expression Regulation, Enzymologic; Introns; Kinetics; Lethal Dose 50; Phylogeny; Protein Domains; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA; Soil Pollutants; Toxicity Tests, Acute; Water Pollutants, Chemical | 2017 |
Expression of Serpin Peptidase Inhibitor B2 (SERPINB2) is regulated by Aryl hydrocarbon receptor (AhR).
Topics: Benzo(a)pyrene; beta-Naphthoflavone; Cell Line, Tumor; Cycloheximide; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Gene Expression; Humans; Ligands; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; RNA Interference; RNA, Small Interfering; Serpins | 2019 |
Molecular characterization of the aryl hydrocarbon receptor 2 gene in black rockfish, Sebastes schlegelii, and its expression patterns upon exposure to benzo[a]pyrene, 2,3,7,8-tetrachlorodibenzo-p-dioxin, and β-naphthoflavone.
Topics: Animals; Benzo(a)pyrene; beta-Naphthoflavone; Body Weight; Mammals; Perciformes; Phylogeny; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger; Xenobiotics | 2022 |