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beta-methylene thiazole-4-carboxamide adenine dinucleotide and adenosine diphosphate

beta-methylene thiazole-4-carboxamide adenine dinucleotide has been researched along with adenosine diphosphate in 6 studies

*Adenosine Diphosphate: Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. [MeSH]

*Adenosine Diphosphate: Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. [MeSH]

Compound Research Comparison

Studies
(beta-methylene thiazole-4-carboxamide adenine dinucleotide)
Trials
(beta-methylene thiazole-4-carboxamide adenine dinucleotide)
Recent Studies (post-2010)
(beta-methylene thiazole-4-carboxamide adenine dinucleotide)
Studies
(adenosine diphosphate)
Trials
(adenosine diphosphate)
Recent Studies (post-2010) (adenosine diphosphate)
60023,9894983,114

Protein Interaction Comparison

ProteinTaxonomybeta-methylene thiazole-4-carboxamide adenine dinucleotide (IC50)adenosine diphosphate (IC50)
Chain A, Kinesin-like protein KIF11Homo sapiens (human)0.45
Heat shock 70 kDa protein 1A Homo sapiens (human)0.5
Sensor protein kinase WalKStaphylococcus aureus7.189

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Colby, TD; Goldstein, BM; Jones, JP; Pankiewicz, KW; Zatorski, A1
Carrell, HL; Goldstein, BM; Hallows, WH; Li, H; Marquez, VE; Pankiewicz, KW; Punzi, JS; Watanabe, KA1
Benhar, I; Davies, DR; Dyda, F; Li, M; Pastan, I1
Abushanab, E; Ikeda, H; Marquez, VE1
Gan, L; Hedstrom, L; Petsko, GA1
Iwamoto, S; Katunuma, N; Marquez, VE; Nagahama, M; Nishizawa, M; Oda, M; Sakurai, J; Tsuge, H; Utsunomiya, H1

Other Studies

6 other study(ies) available for beta-methylene thiazole-4-carboxamide adenine dinucleotide and adenosine diphosphate

ArticleYear
Potent inhibitors of human inosine monophosphate dehydrogenase type II. Fluorine-substituted analogues of thiazole-4-carboxamide adenine dinucleotide.
    Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Fluorine; Horses; Humans; IMP Dehydrogenase; NAD; Recombinant Proteins; Thiazoles

1995
Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin.
    Biochemistry, 1994, Jan-11, Volume: 33, Issue:1

    Topics: Adenosine Diphosphate; Alcohol Dehydrogenase; Amino Acid Sequence; Animals; Antineoplastic Agents; Binding Sites; Crystallography, X-Ray; Horses; Ligands; Liver; Models, Molecular; Molecular Structure; Organoselenium Compounds; Protein Conformation; Ribavirin; Thiazoles

1994
Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jul-09, Volume: 93, Issue:14

    Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Bacterial Toxins; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Exotoxins; Models, Molecular; NAD; Poly(ADP-ribose) Polymerases; Protein Conformation; Protein Structure, Secondary; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Recombinant Proteins; Thiazoles; Virulence Factors

1996
The assembly of beta-methylene-TAD, a metabolically stable analogue of the antitumor agent TAD, by the stepwise esterification of monodeprotected methylenebis-(phosphonate) benzyl esters under Mitsunobu conditions.
    Bioorganic & medicinal chemistry letters, 1999, Nov-01, Volume: 9, Issue:21

    Topics: Adenosine Diphosphate; Antineoplastic Agents; Esterification; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphonates; Phosphoric Diester Hydrolases; Thiazoles

1999
Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis.
    Biochemistry, 2002, Nov-05, Volume: 41, Issue:44

    Topics: Adenosine Diphosphate; Animals; Binding Sites; Catalytic Domain; Cations, Monovalent; Crystallization; Crystallography, X-Ray; Enzyme Activation; Enzyme Activators; Hydrogen Bonding; IMP Dehydrogenase; Inosine Monophosphate; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; NAD; Potassium; Protein Structure, Tertiary; Protozoan Proteins; Thiazoles; Tritrichomonas foetus

2002
Structural basis of actin recognition and arginine ADP-ribosylation by Clostridium perfringens iota-toxin.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, May-27, Volume: 105, Issue:21

    Topics: Actins; Adenosine Diphosphate; ADP Ribose Transferases; Animals; Arginine; Bacterial Toxins; Crystallography, X-Ray; Hydrolysis; Mutagenesis, Site-Directed; Protein Conformation; Rabbits; Ribose; Thiazoles

2008
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