beta-methylcrotonylglycine has been researched along with glycine in 27 studies
| Studies (beta-methylcrotonylglycine) | Trials (beta-methylcrotonylglycine) | Recent Studies (post-2010) (beta-methylcrotonylglycine) | Studies (glycine) | Trials (glycine) | Recent Studies (post-2010) (glycine) |
|---|---|---|---|---|---|
| 27 | 0 | 4 | 35,163 | 756 | 8,415 |
| Protein | Taxonomy | beta-methylcrotonylglycine (IC50) | glycine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 1.4852 | |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | 106 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | 128 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (33.33) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 9 (33.33) | 29.6817 |
| 2010's | 4 (14.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hähnel, R; Wysocki, SJ | 1 |
| Holme, E; Jacobson, CE; Kristiansson, B | 1 |
| Bachmann, C; Dionisi-Vici, C; Graziani, MC; Sabetta, G | 1 |
| Mock, DM; Mock, NI; Weintraub, S | 1 |
| Baker, H; Baswell, DL; Holman, RT; Mock, DM; Sweetman, L | 1 |
| Greter, J; Holme, E; Koivikko, M; Lindstedt, S | 1 |
| Bartlett, K; Leonard, JV; Ng, H | 1 |
| Borud, O; Chalmers, RA; Purkiss, P | 1 |
| Baker, H; Nyhan, WL; Peterson, RM; Surh, L; Sweetman, L | 1 |
| Berry, SA; Nyhan, WL; Thuy, LP; Tuchman, M | 1 |
| Berry, SA; Gage, DA; Huang, ZH; Iwamoto, T; Johnston, K; Millington, DS; Packman, S; Röschinger, W; Sweetman, L; Yano, S | 1 |
| Aleck, KA; Heidenreich, RA; Pearson, MA | 1 |
| Bakkeren, J; Baumgartner, R; de Jong, J; Mourmans, J; Suormala, T; van Diggelen, OP; Wendel, U; Wevers, R | 1 |
| Yoshida, I | 1 |
| Ogier de Baulny, H; Saudubray, JM | 1 |
| Mock, DM; Mock, NI | 1 |
| Almashanu, S; Baumgartner, ER; Baumgartner, MR; Dantas, MF; Fowler, B; Friebel, D; Gebhardt, B; Giunta, C; Hoffmann, GF; Suormala, T; Valle, D | 1 |
| Baumgartner, MR; Baykal, T; Can, G; Dantas, MF; Demir, F; Demirkol, M; Fowler, B; Gokcay, GH; Ince, Z | 1 |
| Barea, L; Baumgartner, MR; Dantas, MF; Fowler, B; Giugliani, R; Graziadio, C; Paskulin, G; Perla, A; Pinto, L; Rosa, R; Vargas, C; Wajner, M; Zen, P | 1 |
| Barshop, BA; Baumgartner, MR; Chambaz, C; Cropcho, LJ; Finegold, DN; Gibson, KM; Koch, HG; Matern, D; Suormala, T; Vockley, J; Walters, N; Wolfe, LA | 1 |
| Kluijtmans, LAJ; Koene, S; Mock, D; Morava, E; Pasch, M; Wevers, R | 1 |
| Baumgartner, MR; Biberoglu, G; Demir, E; Eminoglu, FT; Hasanoglu, A; Okur, I; Ozcelik, AA; Tumer, L | 1 |
| Amaral, AU; Beskow, AP; da Silva, Lde B; Fernandes, CG; Leipnitz, G; Ribeiro, CA; Seminotti, B; Vargas, CR; Wajner, M; Zanatta, A | 1 |
| Busanello, EN; Moura, AP; Ribeiro, CA; Tonin, AM; Wajner, M; Zanatta, Â | 1 |
| Choi, JH; Jung, CW; Kim, GH; Kim, JH; Lee, BH; Lee, J; Yoo, HW | 1 |
| Baumgartner, MR; Burda, P; Bürer, C; Fowler, B; Grünert, SC; Morscher, RJ; Suormala, T | 1 |
| Caruso, U; Cassanello, M; D'Onofrio, V; Enea, A; Garrone, G; Guala, G; Poma, F; Porta, F; Puccinelli, P; Santarelli, F; Spada, M | 1 |
2 review(s) available for beta-methylcrotonylglycine and glycine
| Article | Year |
|---|---|
[3-Methylcrotonyl-CoA carboxylase deficiency].
Topics: Amino Acid Metabolism, Inborn Errors; Carbon-Carbon Ligases; Diagnosis, Differential; Glycine; Humans; Leucine; Prognosis | 1998 |
Branched-chain organic acidurias.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Diagnosis, Differential; Glycine; Hemiterpenes; Humans; Infant, Newborn; Malonates; Maple Syrup Urine Disease; Methylmalonic Acid; Pentanoic Acids; Prognosis; Propionates | 2002 |
25 other study(ies) available for beta-methylcrotonylglycine and glycine
| Article | Year |
|---|---|
3-Methylcrotonylglycine excretion in 3-hydroxy-3-methylglutaric aciduria.
Topics: Crotonates; Glutarates; Glycine; Humans; Hydroxy Acids; Infant; Male; Metabolism, Inborn Errors | 1978 |
Biotin-responsive multiple carboxylase deficiency in an 8-year-old boy with normal serum biotinidase and fibroblast holocarboxylase-synthetase activities.
Topics: Amidohydrolases; Biotin; Biotinidase; Carbon-Nitrogen Ligases; Child; Fibroblasts; Glycine; Humans; Kinetics; Ligases; Male; Multiple Carboxylase Deficiency; Valerates | 1988 |
Laryngeal stridor as a leading symptom in a biotinidase-deficient patient.
Topics: Amidohydrolases; Biotinidase; Female; Glycine; Humans; Infant; Lactates; Larynx; Propionates; Valerates | 1988 |
Abnormal organic aciduria in biotin deficiency: the rat is similar to the human.
Topics: Animals; Biotin; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glycine; Male; Random Allocation; Rats; Rats, Inbred Strains; Valerates | 1988 |
Biotin deficiency complicating parenteral alimentation: diagnosis, metabolic repercussions, and treatment.
Topics: Alopecia; Biotin; Citrates; Diagnosis, Differential; Erythema; Fatty Acids, Essential; Female; Glycine; Humans; Infant; Isomerism; Lactates; Lactic Acid; Male; Nervous System Diseases; Parenteral Nutrition; Valerates; Zinc | 1985 |
Biotin-responsive 3-methylcrotonylglycinuria with biotinidase deficiency.
Topics: Amidohydrolases; Biotin; Biotinidase; Carbon-Carbon Ligases; Child, Preschool; Glycine; Humans; Ligases; Male | 1985 |
A combined defect of three mitochondrial carboxylases presenting as biotin-responsive 3-methylcrotonyl glycinuria and 3-hydroxyisovaleric aciduria.
Topics: Acidosis; Acyl Coenzyme A; Amino Acid Metabolism, Inborn Errors; Biotin; Butyrates; Carbon Dioxide; Carboxy-Lyases; Child, Preschool; Crotonates; Female; Fibroblasts; Glycine; Humans; Hydroxy Acids; Ligases; Mitochondria; Propionates; Pyruvate Carboxylase Deficiency Disease; Valerates | 1980 |
Combined iminoglycinuria and cystine- and dibasic aminoaciduria in patients with propionic acidaemia and 3-methylcrotonylglycinuria.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Amino Acids, Diamino; Child; Child, Preschool; Crotonates; Cystinuria; Glycine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Propionates | 1980 |
Clinical and metabolic abnormalities in a boy with dietary deficiency of biotin.
Topics: Alopecia; Biotin; Carbon-Carbon Ligases; Carboxy-Lyases; Child; Citrates; Diet; Egg Proteins; Facial Dermatoses; Glycine; Humans; Hydroxy Acids; Ligases; Male; Methylmalonyl-CoA Decarboxylase; Propionates; Skin Diseases | 1981 |
Partial methylcrotonyl-coenzyme A carboxylase deficiency in an infant with failure to thrive, gastrointestinal dysfunction, and hypertonia.
Topics: Biotin; Carbon-Carbon Ligases; Failure to Thrive; Gastrointestinal Diseases; Glycine; Humans; Infant; Ligases; Male; Metabolism, Inborn Errors; Muscle Hypertonia; Valerates | 1993 |
3-Hydroxyisovalerylcarnitine in patients with deficiency of 3-methylcrotonyl CoA carboxylase.
Topics: Carbon-Carbon Ligases; Carnitine; Child, Preschool; Female; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Ligases; Male; Valerates | 1995 |
Benign clinical presentation of 3-methylcrotonylglycinuria.
Topics: Carbon-Carbon Ligases; Child, Preschool; Dietary Proteins; Glycine; Humans; Ligases; Male | 1995 |
Isolated (biotin-resistant) 3-methylcrotonyl-CoA carboxylase deficiency: four sibs devoid of pathology.
Topics: Carbon-Carbon Ligases; Carnitine; Child; Child, Preschool; Dietary Proteins; Female; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Infant; Ligases; Male; Valerates | 1995 |
Lymphocyte propionyl-CoA carboxylase is an early and sensitive indicator of biotin deficiency in rats, but urinary excretion of 3-hydroxypropionic acid is not.
Topics: Animals; Biomarkers; Biotin; Carboxy-Lyases; Deficiency Diseases; Glycine; Lactic Acid; Lymphocytes; Male; Methylmalonyl-CoA Decarboxylase; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2002 |
Isolated 3-methylcrotonyl-CoA carboxylase deficiency: evidence for an allele-specific dominant negative effect and responsiveness to biotin therapy.
Topics: Alleles; Base Sequence; Biotin; Carbon-Carbon Ligases; DNA Mutational Analysis; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression; Genetic Vectors; Germany; Glycine; Greece; Humans; Infant, Newborn; Male; Mitochondrial Diseases; Molecular Sequence Data; Mutation; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Transfection; Valerates | 2004 |
Consanguineous 3-methylcrotonyl-CoA carboxylase deficiency: early-onset necrotizing encephalopathy with lethal outcome.
Topics: Carbon-Carbon Ligases; Consanguinity; Diagnosis, Differential; Fatal Outcome; Glycine; Humans; Infant; Infant, Newborn; Leukoencephalitis, Acute Hemorrhagic; Male; Metabolism, Inborn Errors; Mutation; RNA Splice Sites; Valerates | 2005 |
Isolated 3-methylcrotonyl-coenzyme A carboxylase deficiency in a child with metabolic stroke.
Topics: Amino Acid Metabolism, Inborn Errors; Carbon-Carbon Ligases; Child, Preschool; Glycine; Humans; Male; Phenotype; Stroke; Valerates | 2006 |
Potential misdiagnosis of 3-methylcrotonyl-coenzyme A carboxylase deficiency associated with absent or trace urinary 3-methylcrotonylglycine.
Topics: Carbon-Carbon Ligases; Child; Diagnostic Errors; Female; Glycine; Humans; Infant; Metabolism, Inborn Errors; Mutation, Missense | 2007 |
Biotin-sensitive 3-methylcrotonylglycinuria in a patient with severe growth delay, ectodermal abnormalities, neonatal progeroid appearance, and developmental delay.
Topics: Abnormalities, Multiple; Aging, Premature; Biotin; Child, Preschool; Developmental Disabilities; Ectoderm; Female; Glycine; Growth Disorders; Humans; Metabolism, Inborn Errors | 2008 |
3-Methylcrotonyl-CoA carboxylase deficiency: phenotypic variability in a family.
Topics: Adult; Brain; Carbon-Carbon Ligases; Carnitine; Cells, Cultured; Child, Preschool; DNA Mutational Analysis; Epilepsy; Fibroblasts; Gene Deletion; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glycine; Humans; Infant; Language Development Disorders; Male; Mutation; Phenotype; Valerates | 2009 |
Striatum is more vulnerable to oxidative damage induced by the metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency as compared to liver.
Topics: Animals; Corpus Striatum; Glutarates; Glutathione; Glycine; Humans; Liver; Male; Meglutol; Oxidative Stress; Oxo-Acid-Lyases; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Valerates | 2009 |
3-Methylcrotonylglycine disrupts mitochondrial energy homeostasis and inhibits synaptic Na(+),K (+)-ATPase activity in brain of young rats.
Topics: Animals; Antioxidants; Brain; Carbon Dioxide; Cerebral Cortex; Creatine Kinase; Cytosol; Electron Transport Chain Complex Proteins; Energy Metabolism; Glycine; Homeostasis; Mitochondria; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Synapses; Thiobarbituric Acid Reactive Substances | 2012 |
Uneventful clinical courses of Korean patients with methylcrotonylglycinuria and their common mutations.
Topics: Asian People; Carbon-Carbon Ligases; Child; Child, Preschool; Disease Progression; Female; Glycine; Humans; Infant; Infant, Newborn; Male; Mutation; Republic of Korea; Urea Cycle Disorders, Inborn; Valerates | 2012 |
A single mutation in MCCC1 or MCCC2 as a potential cause of positive screening for 3-methylcrotonyl-CoA carboxylase deficiency.
Topics: Acyl Coenzyme A; Carbon-Carbon Ligases; Carnitine; Cells, Cultured; Child; Child, Preschool; DNA Mutational Analysis; Female; Fibroblasts; Glycine; Heterozygote; Humans; Infant; Infant, Newborn; Male; Mutation; Neonatal Screening; Real-Time Polymerase Chain Reaction; Skin; Urea Cycle Disorders, Inborn | 2012 |
A neonatal case of 3-hydroxy-3-methylglutaric-coenzyme A lyase deficiency.
Topics: Acetyl-CoA C-Acetyltransferase; Acidosis; Acute Disease; Amino Acid Metabolism, Inborn Errors; Glutarates; Glycine; Humans; Hypoglycemia; Infant, Newborn; Male; Meglutol | 2013 |