beta-methyl-6-chloromelatonin has been researched along with melatonin in 7 studies
*Melatonin: A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. [MeSH]
*Melatonin: A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. [MeSH]
| Studies (beta-methyl-6-chloromelatonin) | Trials (beta-methyl-6-chloromelatonin) | Recent Studies (post-2010) (beta-methyl-6-chloromelatonin) | Studies (melatonin) | Trials (melatonin) | Recent Studies (post-2010) (melatonin) |
|---|---|---|---|---|---|
| 8 | 3 | 1 | 23,268 | 1,451 | 9,627 |
| Protein | Taxonomy | beta-methyl-6-chloromelatonin (IC50) | melatonin (IC50) |
|---|---|---|---|
| Myeloperoxidase | Homo sapiens (human) | 3 | |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | 3.3323 | |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.0004 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0005 | |
| Melatonin receptor type 1A | Homo sapiens (human) | 0.0025 | |
| Melatonin receptor type 1B | Homo sapiens (human) | 0.0035 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerzer, R; Nickelsen, T; Samel, A; Smith, B; Vejvoda, M; Wenzel, J | 1 |
| Goldwater, DR; Mulchahey, JJ; Zemlan, FP | 1 |
| Gillette, MU; Turek, FW | 1 |
| Lankford, A; Mayleben, DW; Mulchahey, JJ; Rosenberg, R; Scharf, MB; Zemlan, FP | 1 |
| Cardinali, DP; Pandi-Perumal, SR; Srinivasan, V; Zisapel, N | 1 |
| Fee, DB; Gabbita, P; Roberts, K; Scheff, N; Scheff, S; Swartz, KR | 1 |
| Brown, GM; Brzezinski, A; Cardinali, DP; Pandi-Perumal, SR; Spence, DW; Srinivasan, V | 1 |
3 review(s) available for beta-methyl-6-chloromelatonin and melatonin
| Article | Year |
|---|---|
Melatonin, sleep, and circadian rhythms: rationale for development of specific melatonin agonists.
Topics: Acetamides; Antioxidants; Humans; Hypothalamus; Indenes; Indoles; Melatonin; Receptors, Melatonin; Sleep Disorders, Circadian Rhythm | 2004 |
Melatonin and sleep in aging population.
Topics: Aged; Aging; Alzheimer Disease; Body Temperature Regulation; Female; Humans; Indenes; Indoles; Male; Melatonin; Pineal Gland; Receptors, Melatonin; Sleep; Sleep Wake Disorders; Suprachiasmatic Nucleus | 2005 |
Melatonin agonists in primary insomnia and depression-associated insomnia: are they superior to sedative-hypnotics?
Topics: Acetamides; Animals; Benzodiazepines; Benzofurans; Clinical Trials as Topic; Cyclopropanes; Depressive Disorder; Humans; Hypnotics and Sedatives; Indenes; Indoles; Melatonin; Sleep Initiation and Maintenance Disorders | 2011 |
3 trial(s) available for beta-methyl-6-chloromelatonin and melatonin
| Article | Year |
|---|---|
Chronobiotic effects of the melatonin agonist LY 156735 following a simulated 9h time shift: results of a placebo-controlled trial.
Topics: Adaptation, Physiological; Adult; Body Temperature; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Humans; Hydrocortisone; Indoles; Jet Lag Syndrome; Male; Melatonin; Motor Activity; Psychomotor Performance | 2002 |
A single blind, placebo controlled, across groups dose escalation study of the safety, tolerability, pharmacokinetics and pharmacodynamics of the melatonin analog beta-methyl-6-chloromelatonin.
Topics: Adolescent; Adult; Area Under Curve; Blood Pressure; Body Temperature; Dose-Response Relationship, Drug; Half-Life; Heart Rate; Humans; Male; Melatonin; Middle Aged; Single-Blind Method; Sleep | 2004 |
The efficacy and safety of the melatonin agonist beta-methyl-6-chloromelatonin in primary insomnia: a randomized, placebo-controlled, crossover clinical trial.
Topics: Adult; Blood Pressure; Body Temperature; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Melatonin; Middle Aged; Placebos; Polysomnography; Psychomotor Performance; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2005 |
1 other study(ies) available for beta-methyl-6-chloromelatonin and melatonin
| Article | Year |
|---|---|
Melatonin-analog, beta-methyl-6-chloromelatonin, supplementation in spinal cord injury.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Melatonin; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2010 |