Compounds > beta-lapachone

beta-lapachone and dactinomycin

beta-lapachone has been researched along with dactinomycin in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
El-Deiry, WS; Meng, RD1
Choi, EK; Dong, GZ; Oh, ET; Park, HJ; Park, KH; Park, MT; Song, CW; Youn, H1

Other Studies

4 other study(ies) available for beta-lapachone and dactinomycin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma.
    Experimental cell research, 2001, Jan-15, Volume: 262, Issue:2

    Topics: Antibiotics, Antineoplastic; Apoptosis; Betulinic Acid; Colonic Neoplasms; Dactinomycin; Dexamethasone; DNA-Binding Proteins; Female; Glioblastoma; Glucocorticoids; Humans; Interferon-gamma; Melanoma; Mutation; Naphthoquinones; Ovarian Neoplasms; Pentacyclic Triterpenes; Prednisolone; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; RNA, Messenger; STAT1 Transcription Factor; Trans-Activators; Triterpenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation

2001
Heat shock increases expression of NAD(P)H:quinone oxidoreductase (NQO1), mediator of beta-lapachone cytotoxicity, by increasing NQO1 gene activity and via Hsp70-mediated stabilisation of NQO1 protein.
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2009, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Cell Death; Cell Line, Tumor; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Heat-Shock Response; HSP70 Heat-Shock Proteins; Humans; Hyperthermia, Induced; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones

2009