beta-lapachone and benzonidazole

beta-lapachone has been researched along with benzonidazole in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's5 (50.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Armstrong, V; Ciudad, K; Ferreira, J; Kemmerling, U; Maya, JD; Morello, A; Orellana, M; Salas, C; Tapia, RA1
de Carvalho da Silva, F; de Castro, SL; Ferreira, SB; Ferreira, VF; Kaiser, CR; Pinto, AC; Pinto, AV; Salomão, K1
Camara, CA; Costa, VA; da Silva Júnior, EN; de Araujo, AS; de Castro, SL; de Melo, IM; de Oliveira, RN; de Simone, CA; de Souza Filho, JD; Diogo, EB; dos Santos, MR; Emery, FS; Menna-Barreto, RF; Valença, WO1
Bourguignon, SC; Carneiro, PF; do Nascimento, SB; dos Santos Júnior, HM; Ferreira, VF; Lechuga, GC; Pinto, AV; Pinto, Mdo C; Resende, JA; Santos, DO1
Ackermann, L; da Silva Júnior, EN; de Castro, SL; Dhawa, U; Jacob, C; Jardim, GAM1
Gong, Q; Hu, J; Li, X; Wang, P; Zhang, X1
Goijman, SG; Stoppani, AO1
Frasch, AC; Goijman, SG; Stoppani, AO1
Brunoro, GV; Caminha, MA; de Moura, KC; Faça, VM; Ferreira, AT; Menna-Barreto, RF; Perales, J; Trugilho, M; Valente, RH1
Cascabulho, CM; Castro, SL; Demarque, KC; Duque, TLA; Guimarães, ACR; Manso, PPA; Menna-Barreto, RF; Meuser-Batista, M; Moura, KCG; Oliveira, GM; Pelajo-Machado, M; Pinto, MDC1

Reviews

2 review(s) available for beta-lapachone and benzonidazole

ArticleYear
Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones.
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Cell Line, Tumor; Cell Proliferation; Chagas Disease; Humans; Leishmania; Neglected Diseases; Neoplasms; Quinones; Trypanosoma cruzi

2019
A comprehensive review on β-lapachone: Mechanisms, structural modifications, and therapeutic potentials.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Drug Discovery; Humans; Naphthoquinones; Neoplasms; Tabebuia

2021

Other Studies

8 other study(ies) available for beta-lapachone and benzonidazole

ArticleYear
Trypanosoma cruzi: activities of lapachol and alpha- and beta-lapachone derivatives against epimastigote and trypomastigote forms.
    Bioorganic & medicinal chemistry, 2008, Jan-15, Volume: 16, Issue:2

    Topics: Animals; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Stereoisomerism; Trypanocidal Agents; Trypanosoma cruzi

2008
Synthesis and anti-Trypanosoma cruzi activity of β-lapachone analogues.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:7

    Topics: Animals; Blood Cells; Chagas Disease; Inhibitory Concentration 50; Life Cycle Stages; Mice; Naphthoquinones; Pyrans; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2011
On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.
    European journal of medicinal chemistry, 2012, Volume: 52

    Topics: Animals; Chemistry Techniques, Synthetic; Click Chemistry; Drug Discovery; Mice; Naphthoquinones; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2012
New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.
    Bioorganic & medicinal chemistry, 2012, Aug-15, Volume: 20, Issue:16

    Topics: Animals; Cell Death; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethylene Oxide; Models, Molecular; Molecular Structure; Naphthoquinones; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells

2012
[Effects of nifurtimox, benznidazole, and beta-lapachone on the metabolism of DNA, RNA and proteins in Trypanosoma cruzi].
    Revista Argentina de microbiologia, 1983, Volume: 15, Issue:4

    Topics: Animals; Depression, Chemical; DNA; DNA Damage; Free Radicals; Naphthoquinones; Nifurtimox; Nitrofurans; Nitroimidazoles; Oxygen; Protein Biosynthesis; RNA; Trypanocidal Agents; Trypanosoma cruzi

1983
[Introduction of changes in the DNA of Trypanosoma cruzi by trypanocidal agents].
    Revista Argentina de microbiologia, 1984, Volume: 16, Issue:2

    Topics: Animals; DNA; DNA Damage; DNA Repair; Free Radicals; Naphthoquinones; Nifurtimox; Nitroimidazoles; Oxidation-Reduction; Trypanocidal Agents; Trypanosoma cruzi

1984
Differential Gel Electrophoresis (DIGE) Evaluation of Naphthoimidazoles Mode of Action: A Study in Trypanosoma cruzi Bloodstream Trypomastigotes.
    PLoS neglected tropical diseases, 2016, Volume: 10, Issue:8

    Topics: Animals; Chagas Disease; Electrophoresis, Gel, Two-Dimensional; Mice; Naphthoquinones; Nifurtimox; Nitroimidazoles; Proteomics; Protozoan Proteins; Trypanocidal Agents; Trypanosoma cruzi

2016
Antiparasitic and anti-inflammatory activities of ß-lapachone-derived naphthoimidazoles in experimental acute Trypanosoma cruzi infection.
    Memorias do Instituto Oswaldo Cruz, 2020, Volume: 115

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Chagas Disease; Disease Models, Animal; Electrocardiography; Male; Mice; Naphthoquinones; Nitroimidazoles; Parasitemia; Time Factors; Trypanocidal Agents

2020