beta-lapachone has been researched along with alpha-lapachone in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 13 (50.00) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Müller, K; Sellmer, A; Wiegrebe, W | 1 |
| Campillo, M; Díaz-Peñate, RG; Estévez-Braun, A; García-Castellano, JM; Pardo, L; Pérez-Sacau, E; Ravelo, AG | 1 |
| Armstrong, V; Ciudad, K; Ferreira, J; Kemmerling, U; Maya, JD; Morello, A; Orellana, M; Salas, C; Tapia, RA | 1 |
| Aguilera, S; Alvareda, EM; Barreiro, EJ; Denis, PA; Dubin, M; Gastellú, C; Paulino, M; Sperandio da Silva, GM; Tapia, O | 1 |
| Bonifazi, EL; Burton, G; León, LG; Misico, RI; Padrón, JM; Ríos-Luci, C | 1 |
| Bonifazi, EL; Burton, G; León, LG; Misico, RI; Montero, JC; Padrón, JM; Pandiella, A; Ríos-Luci, C | 1 |
| Bourguignon, SC; Carneiro, PF; do Nascimento, SB; dos Santos Júnior, HM; Ferreira, VF; Lechuga, GC; Pinto, AV; Pinto, Mdo C; Resende, JA; Santos, DO | 1 |
| Altig, J; Antipin, MY; Evdokimov, NM; Jenkins, AR; Kireev, AS; Kornienko, A; Lima, DT; Magedov, IV; Steelant, WF; Tongwa, P; Van slambrouck, S | 1 |
| Caira, MR; da Silva Júnior, EN; Davies-Coleman, MT; de la Mare, JA; Edkins, AL; Hendricks, DT; Osoniyi, O; Pinto, AV; Shunmoogam-Gounden, N; Sunassee, SN; Veale, CG | 1 |
| Camara, CA; da Silva, EN; de Melo, IM; de Oliveira, RN; Diogo, EB; do Monte-Neto, RL; Ferreira, VF; Frézard, F; Guimarães, TT; Lanza, JS; Melo, MN; Pinto, Mdo C; Valença, WO | 1 |
| Bian, J; Li, X; Wang, N; Wu, X; You, Q; Zhang, X | 1 |
| Clamor, C; Löcken, H; Müller, K | 1 |
| Ihara, M; Iida, A; Nagai, S; Sagara, M; Saito, K; Tahara, T; Watanabe, A; Yamano, Y; Yamashita, M; Yutani, M | 1 |
| Beteck, RM; Legoabe, LJ; Patel, OPS | 1 |
| Clemente de Moraes, D; do Carmo Freire Ribeiro Pinto, M; do Valle Pereira Midlej, V; Ferreira-Pereira, A; Tenório Sousa Domingos, L | 1 |
| Bastow, KF; Krishnan, P | 2 |
| Araújo, HP; Bourguignon, SC; Cavalcanti, DF; da Silva, MN; de Souza, MC; Ferreira, VF; Gouvêa, RM; Jorqueira, A; Santos, DO; Zuma, AA | 1 |
| Araújo, HP; Bourguignon, SC; Castro, HC; da Silva, MN; de Souza, MC; Ferreira, VF; Gouvêa, RM; Jorqueira, A; Pinto, AV; Rodrigues, CR; Santos, DO; Souza, AM | 1 |
| Barros, FW; Costa-Lotufo, LV; da Silva Júnior, EN; de Moraes, MO; de Souza, MC; Ferreira, VF; Goulart, MO; Montenegro, RC; Pessoa, C; Pinto, AV; Pinto, Mdo C | 1 |
| Alexandre Moreira, MS; Amatore, C; Arbault, S; Bouret, Y; Ferreira, DC; Goulart, MO; Tapsoba, I; Ventura Pinto, A | 1 |
| Albuquerque, MG; Alves, CR; Bourguignon, SC; Castro, HC; Cavalcanti, DF; da Silva, FC; da Silva, GG; de Pinho, RT; de Souza, AM; Ferreira, VF; Rodrigues, CR; Santos, DO | 1 |
| Cheng, SC; Du, L; Li, MD; Li, X; Phillips, DL; Xue, J; Zhang, X; Zhang, Y; Zhu, R | 1 |
| Golonka, AN; Schindler, CS; Watson, RB | 1 |
| Green, IR; Hussain, H | 1 |
| Anjos, CA; Curvelo, JAR; Moraes, DC; Moura, KCG; Pinto, MCFR; Portela, MB; Soares, RMA | 1 |
2 review(s) available for beta-lapachone and alpha-lapachone
| Article | Year |
|---|---|
Antimalarial application of quinones: A recent update.
Topics: Antimalarials; Dose-Response Relationship, Drug; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinones; Structure-Activity Relationship | 2021 |
Lapachol and lapachone analogs: a journey of two decades of patent research(1997-2016).
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Design; Humans; Naphthoquinones; Neoplasms; Patents as Topic; Tabebuia | 2017 |
24 other study(ies) available for beta-lapachone and alpha-lapachone
| Article | Year |
|---|---|
Potential antipsoriatic agents: lapacho compounds as potent inhibitors of HaCaT cell growth.
Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Cell Division; Cell Line; Humans; Keratinocytes; Keratolytic Agents; L-Lactate Dehydrogenase; Naphthoquinones; Psoriasis; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1999 |
Synthesis and pharmacophore modeling of naphthoquinone derivatives with cytotoxic activity in human promyelocytic leukemia HL-60 cell line.
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Furans; HL-60 Cells; Humans; Models, Molecular; Naphthoquinones; Phenanthrenes; Pyrans; Structure-Activity Relationship | 2007 |
Trypanosoma cruzi: activities of lapachol and alpha- and beta-lapachone derivatives against epimastigote and trypomastigote forms.
Topics: Animals; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Stereoisomerism; Trypanocidal Agents; Trypanosoma cruzi | 2008 |
Studies of trypanocidal (inhibitory) power of naphthoquinones: evaluation of quantum chemical molecular descriptors for structure-activity relationships.
Topics: Animals; Naphthoquinones; Quantitative Structure-Activity Relationship; Quantum Theory; Trypanocidal Agents; Trypanosoma cruzi; Trypanosomatina | 2008 |
Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Lipids; Magnetic Resonance Spectroscopy; Naphthoquinones; Prenylation; Structure-Activity Relationship | 2010 |
β-Lapachone analogs with enhanced antiproliferative activity.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases; Humans; Naphthoquinones; Reactive Oxygen Species; Topoisomerase Inhibitors | 2012 |
New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.
Topics: Animals; Cell Death; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethylene Oxide; Models, Molecular; Molecular Structure; Naphthoquinones; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 2012 |
Structural simplification of bioactive natural products with multicomponent synthesis. 4. 4H-pyrano-[2,3-b]naphthoquinones with anticancer activity.
Topics: Antineoplastic Agents; Apoptosis; Biological Products; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Jurkat Cells; MCF-7 Cells; Molecular Conformation; Naphthoquinones; Structure-Activity Relationship | 2012 |
Cytotoxicity of lapachol, β-lapachone and related synthetic 1,4-naphthoquinones against oesophageal cancer cells.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Esophageal Neoplasms; Humans; Mice; Models, Molecular; Molecular Structure; Naphthoquinones; NIH 3T3 Cells; Structure-Activity Relationship | 2013 |
Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition.
Topics: Alkynes; Animals; Antimony; Antiprotozoal Agents; Azides; Catalysis; Cell Survival; Cells, Cultured; Copper; Cycloaddition Reaction; Drug Resistance; Leishmania; Leishmania infantum; Macrophages, Peritoneal; Mice; Naphthoquinones; Parasitic Sensitivity Tests; Species Specificity; Triazoles | 2013 |
Discovery of quinone-directed antitumor agents selectively bioactivated by NQO1 over CPR with improved safety profile.
Topics: Antineoplastic Agents; Benzoquinones; Binding Sites; Cell Death; Drug Discovery; Humans; Molecular Docking Simulation; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Patient Safety; Reactive Oxygen Species; Structure-Activity Relationship | 2017 |
Napabucasin and Related Heterocycle-Fused Naphthoquinones as STAT3 Inhibitors with Antiproliferative Activity against Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Naphthoquinones; Phosphorylation; Reactive Oxygen Species; STAT3 Transcription Factor | 2018 |
STAT3 inhibitory activity of naphthoquinones isolated from Tabebuia avellanedae.
Topics: Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Molecular Structure; Naphthoquinones; STAT3 Transcription Factor; Structure-Activity Relationship; Tabebuia | 2020 |
Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata.
Topics: Antifungal Agents; Biofilms; Candida albicans; Candida glabrata; Membrane Transport Proteins; Naphthoquinones; Saccharomyces cerevisiae | 2022 |
Novel mechanisms of DNA topoisomerase II inhibition by pyranonaphthoquinone derivatives-eleutherin, alpha lapachone, and beta lapachone.
Topics: Adenosine Triphosphate; Bacteria; Binding Sites; Catalysis; DNA; DNA Topoisomerases, Type II; Enzyme Inhibitors; Fungi; Mercaptoethanol; Naphthoquinones; Topoisomerase II Inhibitors | 2000 |
Novel mechanism of cellular DNA topoisomerase II inhibition by the pyranonaphthoquinone derivatives alpha-lapachone and beta-lapachone.
Topics: Colony-Forming Units Assay; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Etoposide; Naphthoquinones; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2001 |
Oxyrane derivative of alpha-lapachone is potent growth inhibitor of Trypanosoma cruzi epimastigote forms.
Topics: Animals; Antiprotozoal Agents; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Fibroblasts; Growth Inhibitors; Naphthoquinones; Trypanosoma cruzi; Vero Cells | 2006 |
Trypanocidal agents with low cytotoxicity to mammalian cell line: a comparison of the theoretical and biological features of lapachone derivatives.
Topics: Animals; Cell Line; Naphthoquinones; Oxidation-Reduction; Static Electricity; Trypanocidal Agents; Trypanosoma cruzi | 2006 |
Synthesis and potent antitumor activity of new arylamino derivatives of nor-beta-lapachone and nor-alpha-lapachone.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; Naphthoquinones; Stereoisomerism; Structure-Activity Relationship | 2007 |
Ex vivo activities of beta-lapachone and alpha-lapachone on macrophages: a quantitative pharmacological analysis based on amperometric monitoring of oxidative bursts by single cells.
Topics: Anti-Infective Agents; Cell Line; Electrochemical Techniques; Macrophages; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Reactive Nitrogen Species; Reactive Oxygen Species; Respiratory Burst | 2009 |
Trypanosoma cruzi: insights into naphthoquinone effects on growth and proteinase activity.
Topics: Animals; Anti-Infective Agents; Chlorocebus aethiops; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Leucine; Naphthoquinones; Peptide Hydrolases; Protease Inhibitors; Protozoan Proteins; Trypanosoma cruzi; Vero Cells | 2011 |
Photoconversion of β-Lapachone to α-Lapachone via a Protonation-Assisted Singlet Excited State Pathway in Aqueous Solution: A Time-Resolved Spectroscopic Study.
Topics: Acetonitriles; Naphthoquinones; Photochemical Processes; Protons; Quantum Theory; Solutions; Spectrum Analysis | 2015 |
Iron(III) Chloride Catalyzed Formation of 3,4-Dihydro-2H-pyrans from α-Alkylated 1,3-Dicarbonyls. Selective Synthesis of α- and β-Lapachone.
Topics: Catalysis; Chlorides; Combinatorial Chemistry Techniques; Ferric Compounds; Humans; Ketones; Molecular Structure; Naphthoquinones; Pyrans | 2016 |
β-lapachone and α-nor-lapachone modulate Candida albicans viability and virulence factors.
Topics: Animals; Antifungal Agents; Candida albicans; Drug Resistance, Fungal; Hyphae; Mice; Naphthoquinones; RAW 264.7 Cells; Virulence; Virulence Factors | 2018 |