Page last updated: 2024-09-04

beta-lactams and tobramycin

beta-lactams has been researched along with tobramycin in 28 studies

Compound Research Comparison

Studies (beta-lactams)	Trials (beta-lactams)	Recent Studies (post-2010) (beta-lactams)	Studies (tobramycin)	Trials (tobramycin)	Recent Studies (post-2010) (tobramycin)
7,579	179	3,395	4,902	629	1,205

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (42.86)	18.7374
1990's	3 (10.71)	18.2507
2000's	3 (10.71)	29.6817
2010's	9 (32.14)	24.3611
2020's	1 (3.57)	2.80

Authors

Authors	Studies
Masuda, G; Nakamura, K; Yajima, T; Yamazaki, E; Yanagishita, T	1
Bangsborg, J; Frimodt-Møller, N; Gutschik, E; Westh, H	1
Cowlishaw, A; Eley, A; Elliott, TS	1
Earl, HS; Sullivan, TJ	1
Chan, LY; Wallace, SM	1
Ackerman, VP; Fernandes, CJ; Stevens, DA	1
Cynamon, MH; Granato, PA	1
Brun, Y; Coulet, M; Fleurette, J; Forey, F; Freney, J	1
Bryan, LE; Godfrey, AJ; Rabin, HR	1
Glew, RH; Pavuk, RA	1
Fass, RJ	1
Marks, MI; Scribner, RK; Tarpay, MM; Weber, AH; Welch, DF	1
Edwards, DJ; Schentag, JJ	1
Ayers, LW; Barnishan, J; Fass, RJ; Solomon, MC	1
Banevicius, MA; Nicolau, DP; Nightingale, CH; Owens, RC; Quintiliani, R	1
Burgess, DS; Hall, RG	1
Ariza, J; Ayats, J; Borraz, C; Cabellos, C; Corbella, X; Doménech, A; Gudiol, F; Montero, A; Tubau, F	1
Darbas, H; Diego, I; Gouby, A; Jean-Pierre, H; Jeannot, JL; Jumas-Bilak, E; Marchandin, H; Teyssier, C	1
Hayes, D; Mansour, HM	1
Bhatt, J; Smyth, AR	1
Brul, S; Feng, Y; Jonker, MJ; Moustakas, I; Ter Kuile, BH	1
Banerjee, R; Boyce, TG; Cunningham, SA; Hasassri, ME; Jeraldo, PR; Kaye, KS; Norgan, AP; Patel, R; Pogue, JM; Weissman, SJ	1
Al-Hasan, MN; Ereshefsky, BJ; Gokun, Y; Martin, CA	1
Bhatt, J; Nevitt, SJ; Smyth, AR	1
Auerbach, AD; Dvorak, CC; Levy, ER; Sabnis, AJ; Wattier, RL	1
Deka, R; Hong, LT; King, JB; Liou, TG; Stevens, V; Young, DC	1
Bonomo, RA; Boyce, JD; Bulitta, JB; Chen, MJ; Deveson Lucas, D; Drusano, GL; Jiao, Y; Kim, TH; Louie, A; Moya, B; Sutaria, DS; Tao, X; Tsai, H; Tsuji, BT; Zavascki, AP	1
Alam, S; Ammeter, D; Brizuela, M; Idowu, T; Jackson, G; Schweizer, F	1

Reviews

3 review(s) available for beta-lactams and tobramycin

Article	Year
Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis. The Cochrane database of systematic reviews, 2012, Feb-15, Issue:2 Topics: Adolescent; Adult; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Humans; Injections, Intravenous; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin; Young Adult	2012
Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis. The Cochrane database of systematic reviews, 2017, 03-27, Volume: 3 Topics: Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Body Mass Index; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Injections, Intravenous; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin; Vital Capacity; Young Adult	2017
Comparable Efficacy and Better Safety of Double β-Lactam Combination Therapy versus β‑Lactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:7 Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Drug Therapy, Combination; Gram-Negative Bacterial Infections; Humans; Randomized Controlled Trials as Topic; Tobramycin; Treatment Outcome	2019

Other Studies

25 other study(ies) available for beta-lactams and tobramycin

Article	Year
[Effect of inhibitory (MIC) and subinhibitory concentrations of tobramycin on bacteriostatic and bactericidal activities of beta-lactam antibiotics (author's transl)]. The Japanese journal of antibiotics, 1979, Volume: 32, Issue:11 Topics: Anti-Bacterial Agents; Bacteria; beta-Lactams; Drug Resistance, Microbial; Drug Synergism; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	1979
Killing curve activity of ciprofloxacin is comparable to synergistic effect of beta-lactam-tobramycin combinations against Haemophilus species endocarditis strains. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1992, Volume: 100, Issue:9 Topics: Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Drug Synergism; Endocarditis, Bacterial; Haemophilus; Humans; Microbial Sensitivity Tests; Tobramycin	1992
Stability of tobramycin in combination with selected new beta-lactam antibiotics. The Journal of antimicrobial chemotherapy, 1986, Volume: 17, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Combinations; Drug Incompatibility; Enterobacter; Staphylococcus aureus; Tobramycin	1986
Acute desensitization of a patient with cystic fibrosis allergic to both beta-lactam and aminoglycoside antibiotics. The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:3 Topics: Adolescent; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Skin Tests; Tobramycin	1987
In vitro interaction of aminoglycosides with beta-lactam penicillins. Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Interactions; Gentamicins; Humans; In Vitro Techniques; Kidney; Kinetics; Models, Theoretical; Statistics as Topic; Tobramycin	1985
Comparative antibacterial activities of new beta-lactam antibiotics against Pseudomonas aeruginosa. Chemotherapy, 1985, Volume: 31, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Resistance, Microbial; Gentamicins; Microbial Sensitivity Tests; Netilmicin; Pseudomonas aeruginosa; Tobramycin	1985
In vitro comparative activity of moxalactam, GR 20263, and N-formimidoyl thienamycin to other beta-lactam antibiotics and tobramycin against enterobacteriaceae and staphylococci. Chemotherapy, 1982, Volume: 28, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactams; Ceftazidime; Cephalosporins; Cephamycins; Enterobacteriaceae; Imipenem; Microbial Sensitivity Tests; Moxalactam; Staphylococcus; Tobramycin	1982
[Effect of storage time at -20 degrees C on the determination of serum concentrations of tobramycin in the presence of 6 beta-lactams]. Pathologie-biologie, 1983, Volume: 31, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactams; Biological Assay; Cold Temperature; Humans; Immunoenzyme Techniques; Specimen Handling; Tobramycin	1983
beta-Lactam-resistant Pseudomonas aeruginosa with modified penicillin-binding proteins emerging during cystic fibrosis treatment. Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:5 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Carrier Proteins; Cystic Fibrosis; Female; Hexosyltransferases; Humans; Muramoylpentapeptide Carboxypeptidase; Penicillin G; Penicillin Resistance; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Piperacillin; Pseudomonas aeruginosa; Sputum; Tobramycin	1981
Stability of gentamicin, tobramycin, and amikacin in combination with four beta-lactam antibiotics. Antimicrobial agents and chemotherapy, 1983, Volume: 24, Issue:4 Topics: Amikacin; Anti-Bacterial Agents; beta-Lactams; Chemistry, Pharmaceutical; Drug Combinations; Drug Stability; Gentamicins; Temperature; Tobramycin	1983
Comparative in vitro activities of beta-lactam-tobramycin combinations against Pseudomonas aeruginosa and multidrug-resistant gram-negative enteric bacilli. Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:6 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Interactions; Drug Resistance, Microbial; Enterobacteriaceae; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	1982
Activities of various beta-lactams and aminoglycosides, alone and in combination, against isolates of Pseudomonas aeruginosa from patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:6 Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Gentamicins; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	1982
In vitro interactions between beta-lactam antibiotics and tobramycin. Clinical chemistry, 1981, Volume: 27, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Cold Temperature; Drug Stability; Kinetics; Penicillinase; Penicillins; Tobramycin	1981
In vitro activities of quinolones, beta-lactams, tobramycin, and trimethoprim-sulfamethoxazole against nonfermentative gram-negative bacilli. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactams; Fluoroquinolones; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Tobramycin; Trimethoprim, Sulfamethoxazole Drug Combination	1996
In vitro synergistic activities of tobramycin and selected beta-lactams against 75 gram-negative clinical isolates. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:11 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Synergism; Drug Therapy, Combination; Gram-Negative Bacteria; Microbial Sensitivity Tests; Tobramycin	1997
In vitro activity of parenteral Beta-lactams, levofloxacin and tobramycin alone or in combination against extended-spectrum Beta-lactamase producing Klebsiella pneumoniae. International journal of antimicrobial agents, 2004, Volume: 24, Issue:1 Topics: beta-Lactamases; beta-Lactams; Drug Therapy, Combination; Infusions, Parenteral; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Tobramycin	2004
Antibiotic combinations for serious infections caused by carbapenem-resistant Acinetobacter baumannii in a mouse pneumonia model. The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:6 Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Colistin; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Humans; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Pneumonia, Bacterial; Rifampin; Tobramycin	2004
Molecular and phenotypic features for identification of the opportunistic pathogens Ochrobactrum spp. Journal of medical microbiology, 2005, Volume: 54, Issue:Pt 10 Topics: Anti-Bacterial Agents; Bacterial Typing Techniques; beta-Lactams; Colistin; Culture Media; DNA, Bacterial; DNA, Ribosomal; Fermentation; Gentian Violet; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Netilmicin; Ochrobactrum; Opportunistic Infections; Oxidoreductases; Phenazines; Ribotyping; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Temperature; Tobramycin; Urease	2005
Improved outcomes of patients with end-stage cystic fibrosis requiring invasive mechanical ventilation for acute respiratory failure. Lung, 2011, Volume: 189, Issue:5 Topics: Acute Disease; Adult; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Female; Humans; Male; Malnutrition; Respiration, Artificial; Respiratory Function Tests; Respiratory Insufficiency; Retrospective Studies; Severity of Illness Index; Tobramycin; Treatment Outcome; Young Adult	2011
Dynamics of Mutations during Development of Resistance by Pseudomonas aeruginosa against Five Antibiotics. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7 Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Ceftazidime; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Microbial; Meropenem; Microbial Sensitivity Tests; Mutation; Piperacillin; Pseudomonas aeruginosa; Thienamycins; Tobramycin	2016
An Immunocompromised Child with Bloodstream Infection Caused by Two Escherichia coli Strains, One Harboring NDM-5 and the Other Harboring OXA-48-Like Carbapenemase. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6 Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; beta-Lactams; Ciprofloxacin; Ertapenem; Escherichia coli; Female; Gentamicins; Humans; Immunocompromised Host; Meropenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam; Thienamycins; Tobramycin	2016
Comparison of ß-lactam plus aminoglycoside versus ß-lactam plus fluoroquinolone empirical therapy in serious nosocomial infections due to Gram-negative bacilli. Journal of chemotherapy (Florence, Italy), 2017, Volume: 29, Issue:1 Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cohort Studies; Critical Illness; Cross Infection; Drug Therapy, Combination; Female; Fluoroquinolones; Gentamicins; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Proportional Hazards Models; Retrospective Studies; Tobramycin; Treatment Outcome	2017
Reducing Second Gram-Negative Antibiotic Therapy on Pediatric Oncology and Hematopoietic Stem Cell Transplantation Services. Infection control and hospital epidemiology, 2017, Volume: 38, Issue:9 Topics: Adolescent; Anti-Bacterial Agents; Antimicrobial Stewardship; beta-Lactams; Child; Child, Preschool; Ciprofloxacin; Drug Combinations; Drug Utilization; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Guidelines as Topic; Hematopoietic Stem Cell Transplantation; Hospitals, Pediatric; Humans; Length of Stay; Medical Oncology; Neutropenia; Pediatrics; Poisson Distribution; San Francisco; Tobramycin; Treatment Outcome	2017
Pharmacokinetics of Continuous Infusion Beta-lactams in the Treatment of Acute Pulmonary Exacerbations in Adult Patients With Cystic Fibrosis. Chest, 2018, Volume: 154, Issue:5 Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Disease Progression; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Retrospective Studies; Symptom Flare Up; Tobramycin	2018
Overcoming β-Lactam resistance in Pseudomonas aeruginosa using non-canonical tobramycin-based antibiotic adjuvants. Bioorganic & medicinal chemistry letters, 2020, 11-01, Volume: 30, Issue:21 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Structure-Activity Relationship; Tobramycin	2020