Compounds > beta-lactams
Page last updated: 2024-09-04

beta-lactams and stilbenes

beta-lactams has been researched along with stilbenes in 6 studies

Compound Research Comparison

Studies
(beta-lactams)		Trials
(beta-lactams)		Recent Studies (post-2010)
(beta-lactams)		Studies
(stilbenes)		Trials
(stilbenes)		Recent Studies (post-2010) (stilbenes)
7,5791793,39513,9352457,836

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Coy, DH; Fuselier, JA; Hocart, SJ; Sun, L; Vasilevich, NI1
Bright, SA; Carr, M; Carroll, P; Conneally, E; Croke, A; Fayne, D; Gagliardi, M; Greene, LM; Keely, NO; Lawler, M; Lloyd, DG; McElligott, AM; Meegan, MJ; Nathwani, SM; O'Boyle, NM; O'Connor, L; Sarkadi, B; Zisterer, DM1
Carr, M; Greene, LM; Knox, AJ; Lloyd, DG; Meegan, MJ; Zisterer, DM1
Fayne, D; Greene, LM; Malebari, AM; Meegan, MJ; Nathwani, SM; O'Boyle, NM; Twamley, B; Wang, S; Zisterer, DM1
Ding, K; Feng, K; Jiang, H; Liang, Y; Liu, M; Luo, C; Wang, J; Wang, X; Wang, Y; Xu, P; Zhang, H; Zhou, P1
Fayne, D; Malebari, AM; Meegan, MJ; Nathwani, SM; Noorani, S; O'Boyle, NM; O'Connell, F; O'Sullivan, J; Twamley, B; Zisterer, DM1

Other Studies

6 other study(ies) available for beta-lactams and stilbenes

ArticleYear
Examination of the 1,4-disubstituted azetidinone ring system as a template for combretastatin A-4 conformationally restricted analogue design.
    Bioorganic & medicinal chemistry letters, 2004, May-03, Volume: 14, Issue:9

    Topics: Animals; Antineoplastic Agents; Azetidines; Cell Line, Tumor; Humans; Mice; Mice, Nude; Models, Molecular; Rats; Stilbenes

2004
The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Azetidines; beta-Lactams; Blotting, Western; Cell Cycle; Cell Proliferation; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Guaiacol; HL-60 Cells; Humans; K562 Cells; Microscopy, Confocal; Microscopy, Fluorescence; Microtubules; Molecular Structure; Stereoisomerism; Stilbenes; Tubulin

2010
Lead identification of conformationally restricted β-lactam type combretastatin analogues: synthesis, antiproliferative activity and tubulin targeting effects.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:12

    Topics: Animals; Antineoplastic Agents; beta-Lactams; Cattle; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tubulin

2010
β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; beta-Lactams; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Glucuronates; HT29 Cells; Humans; Inactivation, Metabolic; Stilbenes; Structure-Activity Relationship

2017
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Animals; Antineoplastic Agents; Apoptosis; beta-Lactams; Cell Cycle; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Mice; Mice, Inbred Strains; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Polymerization; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2018
β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells.
    European journal of medicinal chemistry, 2020, Mar-01, Volume: 189

    Topics: Antineoplastic Agents; Apoptosis; beta-Lactams; Binding Sites; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; HEK293 Cells; Humans; Microsomes, Liver; Molecular Docking Simulation; Molecular Structure; Necrosis; Protein Binding; Stilbenes; Survivin; Tubulin; Tubulin Modulators

2020