Page last updated: 2024-09-04

beta-lactams and probenecid

beta-lactams has been researched along with probenecid in 5 studies

Compound Research Comparison

Studies
(beta-lactams)
Trials
(beta-lactams)
Recent Studies (post-2010)
(beta-lactams)
Studies
(probenecid)
Trials
(probenecid)
Recent Studies (post-2010) (probenecid)
7,5791793,3953,664292375

Protein Interaction Comparison

ProteinTaxonomybeta-lactams (IC50)probenecid (IC50)
Solute carrier family 22 member 8Mus musculus (house mouse)3.02
Solute carrier family 22 member 6Homo sapiens (human)6.85
Solute carrier family 22 member 8Homo sapiens (human)6.965
Solute carrier family 22 member 8Rattus norvegicus (Norway rat)6.03

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Egger, HJ; Stoeckel, K; Weidekamm, E; Ziegler, WH1
Aungst, BJ; Fujisaki, H; Miyazaki, K; Saitoh, H1
Begg, EJ; Chin, PKL; Everts, R; Moore, GA; Zhang, M1
Gallien, S; Habibi, A; Hulin, A; Huriez, P; Lepeule, R; Ourghanlian, C; Razazi, K; Vindrios, W1
Arkell, P; Gilchrist, M; Holmes, AH; Hope, W; Rawson, TM; Riezk, A; Wheeler, G; Wilson, RC1

Reviews

1 review(s) available for beta-lactams and probenecid

ArticleYear
Addition of probenecid to oral β-lactam antibiotics: a systematic review and meta-analysis.
    The Journal of antimicrobial chemotherapy, 2022, 08-25, Volume: 77, Issue:9

    Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactams; Gonorrhea; Humans; Monobactams; Probenecid

2022

Trials

1 trial(s) available for beta-lactams and probenecid

ArticleYear
Single-dose pharmacokinetics of Ro 17-2301 (AMA-1080), a monocyclic beta-lactam, in humans.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Clinical Trials as Topic; Dialysis; Feces; Half-Life; Humans; Kidney Glomerulus; Kinetics; Male; Probenecid; Protein Binding; Ultrafiltration

1984

Other Studies

3 other study(ies) available for beta-lactams and probenecid

ArticleYear
Restricted intestinal absorption of some beta-lactam antibiotics by an energy-dependent efflux system in rat intestine.
    Pharmaceutical research, 1997, Volume: 14, Issue:5

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Energy Metabolism; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; p-Aminohippuric Acid; Probenecid; Rats; Spectrophotometry, Ultraviolet; Uricosuric Agents; Verapamil

1997
Simultaneous Determination of Cefalexin, Cefazolin, Flucloxacillin, and Probenecid by Liquid Chromatography-Tandem Mass Spectrometry for Total and Unbound Concentrations in Human Plasma.
    Therapeutic drug monitoring, 2018, Volume: 40, Issue:6

    Topics: Adjuvants, Pharmaceutic; Adolescent; Adult; Aged; Aged, 80 and over; beta-Lactams; Cefazolin; Cephalexin; Child; Chromatography, High Pressure Liquid; Drug Monitoring; Floxacillin; Humans; Limit of Detection; Middle Aged; Plasma; Probenecid; Tandem Mass Spectrometry; Young Adult

2018
Probenecid, an old β-lactams pharmacokinetic enhancer for a renewed use: A retrospective study.
    Infectious diseases now, 2022, Volume: 52, Issue:5

    Topics: Anemia, Sickle Cell; Anti-Bacterial Agents; beta-Lactams; Humans; Probenecid; Retrospective Studies

2022