Page last updated: 2024-09-04

beta-lactams and orlistat

beta-lactams has been researched along with orlistat in 2 studies

Compound Research Comparison

Studies
(beta-lactams)
Trials
(beta-lactams)
Recent Studies (post-2010)
(beta-lactams)
Studies
(orlistat)
Trials
(orlistat)
Recent Studies (post-2010) (orlistat)
7,5791793,3951,432274539

Protein Interaction Comparison

ProteinTaxonomybeta-lactams (IC50)orlistat (IC50)
Phosphatidylserine lipase ABHD16AHomo sapiens (human)0.1
Pancreatic triacylglycerol lipaseSus scrofa (pig)0.4214
Lipoprotein lipaseHomo sapiens (human)0.066
Cytochrome P450 3A4Homo sapiens (human)0.42
Hepatic triacylglycerol lipaseHomo sapiens (human)0.003
Pancreatic triacylglycerol lipaseHomo sapiens (human)0.3253
Translocator proteinRattus norvegicus (Norway rat)1
Cytochrome P450 2C19Homo sapiens (human)0.42
Kappa-type opioid receptorMus musculus (house mouse)0.1903
Fatty acid synthaseHomo sapiens (human)2.99
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)0.01
Platelet-activating factor acetylhydrolaseHomo sapiens (human)0.05
Diacylglycerol lipase-alphaMus musculus (house mouse)0.02
Lysophosphatidylserine lipase ABHD12Homo sapiens (human)0.1682
Diacylglycerol lipase-betaHomo sapiens (human)0.24
Monoacylglycerol lipase ABHD6Homo sapiens (human)0.03
Acyl-protein thioesterase 2Rattus norvegicus (Norway rat)0.17
Diacylglycerol lipase-alphaHomo sapiens (human)0.2677
Endothelial lipaseHomo sapiens (human)0.006

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chamni, S; Richardson, RD; Romo, D; Smith, JW; Zhang, W1
Aubert, G; Aubry, S; Cresteil, T; Crich, D1

Other Studies

2 other study(ies) available for beta-lactams and orlistat

ArticleYear
Beta-lactam congeners of orlistat as inhibitors of fatty acid synthase.
    Bioorganic & medicinal chemistry letters, 2008, Apr-01, Volume: 18, Issue:7

    Topics: Anti-Obesity Agents; Antineoplastic Agents; beta-Lactams; Binding Sites; Enzyme Inhibitors; Fatty Acid Synthases; Humans; Inhibitory Concentration 50; Lactones; Models, Chemical; Orlistat; Stereoisomerism; Structure-Activity Relationship

2008
Synthesis and biological investigation of the β-thiolactone and β-lactam analogs of tetrahydrolipstatin.
    Organic & biomolecular chemistry, 2012, Apr-07, Volume: 10, Issue:13

    Topics: Animals; beta-Lactams; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Humans; Lactones; Lipase; Molecular Structure; Orlistat; Pancreas; Sulfhydryl Compounds

2012