beta-lactams has been researched along with lysine in 22 studies
| Studies (beta-lactams) | Trials (beta-lactams) | Recent Studies (post-2010) (beta-lactams) | Studies (lysine) | Trials (lysine) | Recent Studies (post-2010) (lysine) |
|---|---|---|---|---|---|
| 7,579 | 179 | 3,395 | 37,449 | 622 | 11,213 |
| Protein | Taxonomy | beta-lactams (IC50) | lysine (IC50) |
|---|---|---|---|
| Cationic amino acid transporter 3 | Homo sapiens (human) | 158 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.64) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 8 (36.36) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Beckman, W; Lessie, TG | 1 |
| Labia, R; Lenfant, F; Masson, JM | 1 |
| Madduri, K; Stuttard, C; Vining, LC | 1 |
| Aharonowitz, Y; Mendelovitz, S | 1 |
| Demain, AL; Fang, A; Keables, P | 1 |
| Liu, L; Shaw, PD | 1 |
| Eriguchi, Y; Haruta, S; Sawai, T; Yamamoto, ET | 1 |
| Arthur, M; Blanot, D; Cremniter, J; Fourgeaud, M; Frehel, C; Gutmann, L; Legrand, R; Mainardi, JL; Morel, V; Van Heijenoort, J | 1 |
| Cha, JY; Golemi-Kotra, D; Meroueh, SO; Mobashery, S; Vakulenko, SB | 1 |
| Chambers, HF; Hills, TL; Strynadka, NC; Wilke, MS; Zhang, HZ | 1 |
| Cha, J; Mobashery, S; Vakulenko, SB | 1 |
| Bernal, P; Hinds, J; Lemaire, S; Mobashery, S; Pinho, MG; Taylor, PW | 1 |
| Baker, BM; Borbulevych, O; Hesek, D; Kumarasiri, M; Lee, M; Llarrull, LI; Mobashery, S; Peng, J; Shi, Q; Wilson, B | 1 |
| Brock, M; Fazius, F; Zaehle, C | 1 |
| Foster, SJ; Rosado, H; Taylor, PW; Turner, RD | 1 |
| Burke, TR; Goydel, RS; Hymel, D; Li, X; Nanna, AR; Pedzisa, L; Rader, C; Roush, WR; Walseng, E | 1 |
| Nanna, AR; Rader, C | 1 |
| Bazan, GC; Chan-Park, MB; Chi, YR; De, PP; Du, Y; Duan, H; Hammond, PT; Jothy, SL; Keogh, D; Kreiswirth, BN; Liu, XW; Liu, Y; Marimuthu, K; Mediavilla, JR; Mu, Y; Ng, OT; Pethe, K; Raju, C; Reghu, S; Ren, J; Ruan, L; Si, Z; Tam, KC; Turvey, ME; Zhang, K; Zhu, Y | 1 |
| Burke, TR; Hwang, D; Park, H; Rader, C; Tsuji, K | 1 |
| Abe, I; Lyu, J; Ushimaru, R | 1 |
| Li, Z; Lin, X; Lin, Y; Song, H; Song, Q; Tang, H; Xie, X; Yao, J; Yao, Z; Zhang, L | 1 |
| Chen, M; Cui, R; Gao, Q; Guo, Y; Hong, S; Huang, H; Niu, J; Su, S; Wang, D; Xiao, L; Xue, Y; Zhao, X | 1 |
22 other study(ies) available for beta-lactams and lysine
| Article | Year |
|---|---|
Response of Pseudomonas cepacia to beta-Lactam antibiotics: utilization of penicillin G as the carbon source.
Topics: beta-Lactams; Cephalosporins; Lysine; Mutation; Penicillin G; Penicillin Resistance; Penicillins; Pseudomonas; Species Specificity | 1979 |
Replacement of lysine 234 affects transition state stabilization in the active site of beta-lactamase TEM1.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Binding Sites; Clavulanic Acid; Clavulanic Acids; DNA, Bacterial; Enzyme Stability; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed | 1991 |
Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Anti-Bacterial Agents; beta-Lactams; Cadaverine; Diamines; Lysine; Molecular Structure; Mutation; Species Specificity; Streptomyces | 1989 |
beta-lactam antibiotic production by Streptomyces clavuligerus mutants impaired in regulation of aspartokinase.
Topics: Anti-Bacterial Agents; Aspartate Kinase; beta-Lactams; Cysteine; Drug Resistance, Microbial; Lysine; Mutation; Phosphotransferases; Streptomyces; Threonine | 1983 |
Unexpected enhancement of beta-lactam antibiotic formation in Streptomyces clavuligerus by very high concentrations of exogenous lysine.
Topics: Anti-Bacterial Agents; beta-Lactams; Culture Media; Lysine; Stereoisomerism; Streptomyces | 1996 |
A possible role for acetylated intermediates in diaminopimelate and tabtoxinine-beta-lactam biosynthesis in Pseudomonas syringae pv. tabaci BR2.024.
Topics: Acetylation; Acetyltransferases; Acyltransferases; Amino Acid Sequence; Azetidines; Bacterial Proteins; Base Sequence; beta-Lactams; Cloning, Molecular; Diaminopimelic Acid; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Lysine; Molecular Sequence Data; Open Reading Frames; Pseudomonas; Restriction Mapping; Sequence Alignment; Sequence Homology, Amino Acid | 1997 |
Characterization of the active-site residues asparagine 167 and lysine 161 of the IMP-1 metallo beta-lactamase.
Topics: Asparagine; beta-Lactamases; beta-Lactams; Binding Sites; Escherichia coli; Humans; Kinetics; Lysine; Mutagenesis, Site-Directed; Zinc | 2001 |
Balance between two transpeptidation mechanisms determines the expression of beta-lactam resistance in Enterococcus faecium.
Topics: Alanine; Ampicillin; Anti-Bacterial Agents; beta-Lactams; Cell Division; Cell Membrane; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cytoplasm; Dipeptides; Drug Resistance; Enterococcus faecium; Escherichia coli; Lysine; Mass Spectrometry; Microscopy, Electron; Models, Biological; Muramoylpentapeptide Carboxypeptidase; Peptidoglycan; Peptidyl Transferases; Protein Structure, Tertiary; Time Factors | 2002 |
Resistance to beta-lactam antibiotics and its mediation by the sensor domain of the transmembrane BlaR signaling pathway in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Binding Sites; Carbon; Carbon Dioxide; Carrier Proteins; Circular Dichroism; Cloning, Molecular; Cytoplasm; DNA Mutational Analysis; Drug Resistance, Microbial; Escherichia coli; Gene Expression Regulation; Hexosyltransferases; Hydrogen-Ion Concentration; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Models, Biological; Models, Molecular; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidyl Transferases; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Signal Transduction; Staphylococcus aureus | 2003 |
Crystal structures of the Apo and penicillin-acylated forms of the BlaR1 beta-lactam sensor of Staphylococcus aureus.
Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactamases; beta-Lactams; Binding Sites; Carrier Proteins; Cell Membrane; Cloning, Molecular; Crystallography, X-Ray; Cytosol; Electrons; Hydrolysis; Light; Lysine; Mass Spectrometry; Models, Biological; Models, Chemical; Models, Molecular; Molecular Sequence Data; Penicillin-Binding Proteins; Penicillins; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Scattering, Radiation; Sequence Homology, Amino Acid; Signal Transduction; Staphylococcus aureus; Temperature | 2004 |
Characterization of the beta-lactam antibiotic sensor domain of the MecR1 signal sensor/transducer protein from methicillin-resistant Staphylococcus aureus.
Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactams; Binding Sites; Carrier Proteins; Circular Dichroism; Cloning, Molecular; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Lysine; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Penicillin-Binding Proteins; Protein Structure, Tertiary; Signal Transduction | 2007 |
Insertion of epicatechin gallate into the cytoplasmic membrane of methicillin-resistant Staphylococcus aureus disrupts penicillin-binding protein (PBP) 2a-mediated beta-lactam resistance by delocalizing PBP2.
Topics: Anisotropy; Anti-Bacterial Agents; beta-Lactams; Catechin; Cell Wall; Cytoplasm; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Lysine; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microscopy, Fluorescence; Oligonucleotide Array Sequence Analysis; Penicillin-Binding Proteins; Phosphatidylglycerols | 2010 |
Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus.
Topics: Bacterial Proteins; beta-Lactams; Binding Sites; Crystallography, X-Ray; Decarboxylation; Lysine; Magnetic Resonance Spectroscopy; Membrane Proteins; Methicillin-Resistant Staphylococcus aureus; Protein Conformation | 2011 |
Lysine biosynthesis in microbes: relevance as drug target and prospects for β-lactam antibiotics production.
Topics: Aconitate Hydratase; Anti-Bacterial Agents; beta-Lactams; Diaminopimelic Acid; Hydro-Lyases; Industrial Microbiology; Lysine; Peptidoglycan | 2013 |
Impact of the β-Lactam Resistance Modifier (-)-Epicatechin Gallate on the Non-Random Distribution of Phospholipids across the Cytoplasmic Membrane of Staphylococcus aureus.
Topics: beta-Lactams; Cardiolipins; Catechin; Cell Membrane; Lysine; Membrane Lipids; Methicillin-Resistant Staphylococcus aureus; Microscopy, Atomic Force; Peptidoglycan; Phenotype; Phosphatidylglycerols; Phospholipids | 2015 |
Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates.
Topics: Animals; Antineoplastic Agents; beta-Lactams; Catalysis; Cell Line, Tumor; Chemistry, Pharmaceutical; Epitopes, T-Lymphocyte; Female; Humans; Hydrogen-Ion Concentration; Immunoconjugates; K562 Cells; Lymphoma, Non-Hodgkin; Lysine; Mice; Multiple Myeloma; Mutation; Neoplasm Transplantation; Pharmaceutical Preparations; Syndecan-1; Trastuzumab; Xenograft Model Antitumor Assays | 2017 |
Engineering Dual Variable Domains for the Generation of Site-Specific Antibody-Drug Conjugates.
Topics: beta-Lactams; Humans; Immunoconjugates; Immunoglobulins; Lysine; Protein Domains; Protein Engineering; Trastuzumab | 2019 |
Enantiomeric glycosylated cationic block co-beta-peptides eradicate Staphylococcus aureus biofilms and antibiotic-tolerant persisters.
Topics: 3T3 Cells; Animals; beta-Lactams; Biofilms; Drug Resistance, Multiple, Bacterial; Glucose; Humans; In Vitro Techniques; Lysine; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Polymerization; Staphylococcal Skin Infections | 2019 |
Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates.
Topics: Antibodies, Monoclonal; beta-Lactams; Breast Neoplasms; Cell Proliferation; Female; Humans; Hydrocarbons, Aromatic; Immunoconjugates; Ketones; Lysine; Ovarian Neoplasms; Protein Engineering; Receptor, ErbB-2; Tumor Cells, Cultured | 2019 |
Characterization of Enzymes Catalyzing the Initial Steps of the β-Lactam Tabtoxin Biosynthesis.
Topics: beta-Lactams; Dipeptides; Lysine; Pseudomonas | 2022 |
The Lysine Acetylation Modification in the Porin Aha1 of Aeromonas hydrophila Regulates the Uptake of Multidrug Antibiotics.
Topics: Acetylation; Aeromonas hydrophila; Anti-Bacterial Agents; beta-Lactams; Drug Resistance, Bacterial; Lysine; Oxytetracycline; Porins | 2022 |
Enhancement of β-Lactam-Mediated Killing of Gram-Negative Bacteria by Lysine Hydrochloride.
Topics: Anti-Bacterial Agents; beta-Lactams; Escherichia coli; Gram-Negative Bacteria; Lysine; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Reactive Oxygen Species | 2023 |