Compounds > beta-lactams
Page last updated: 2024-09-04

beta-lactams and glycine

beta-lactams has been researched along with glycine in 8 studies

Compound Research Comparison

Studies
(beta-lactams)		Trials
(beta-lactams)		Recent Studies (post-2010)
(beta-lactams)		Studies
(glycine)		Trials
(glycine)		Recent Studies (post-2010) (glycine)
7,5791793,39535,1637568,415

Protein Interaction Comparison

ProteinTaxonomybeta-lactams (IC50)glycine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.4852
Sodium- and chloride-dependent glycine transporter 1Homo sapiens (human)106
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.3253
Sodium- and chloride-dependent glycine transporter 2Homo sapiens (human)128

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boyd, DB1
Bose, AK; Chawla, HP; Dayal, B; Manhas, MS1
Dorman, DE; Engel, GL; Indelicato, JM1
Gabor, EM; Janssen, DB1
Bonomo, RA; Buynak, JD; Carey, PR; Helfand, MS; Taracila, MA; Totir, MA; van den Akker, F1
Cao, Y; Pan, Y; Wang, L; Ye, LJ1
Brown, NG; Horton, LB; Lykissa, E; Mikulski, R; Palzkill, T; Phillips, KJ; Shanker, S; Venkataram Prasad, BV1
Acosta-Gutiérrez, S; Bodrenko, I; Ceccarelli, M; Ferrara, L; Masi, M; Naismith, JH; Page, MGP; Pagès, JM; Pathania, M; Stavenger, RA; van den Berg, B; Wang, J; Winterhalter, M; Zahn, M1

Other Studies

8 other study(ies) available for beta-lactams and glycine

ArticleYear
Transition state structures of a dipeptide related to the mode of action of beta-lactam antibiotics.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:12

    Topics: beta-Lactams; Cephalosporins; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Molecular Conformation; Penicillins; Structure-Activity Relationship

1977
Studies on lactams. Part XLII. A stereoselective synthesis of some alpha-amido-beta-lactams.
    Journal of the Chemical Society. Perkin transactions 1, 1975, Issue:19

    Topics: Amides; beta-Lactams; Glycine; Methods; Penicillins; Stereoisomerism

1975
2-Hydroxy-3-aryl-6-methylpyrazines-fluorophores formed from the reaction of formaldehyde with cyclic enamine degradation products common to beta-lactam antibiotics with aryl glycine side chains.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:2

    Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactams; Cephalexin; Chemical Phenomena; Chemistry; Formaldehyde; Glycine; Hydrolysis; Pyrazines; Spectrometry, Fluorescence

1981
Increasing the synthetic performance of penicillin acylase PAS2 by structure-inspired semi-random mutagenesis.
    Protein engineering, design & selection : PEDS, 2004, Volume: 17, Issue:7

    Topics: beta-Lactams; Catalysis; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Escherichia coli; Genetic Techniques; Glycine; Hydrolysis; Kinetics; Models, Chemical; Mutagenesis; Mutation; Penicillanic Acid; Penicillin Amidase; Plasmids; Protein Conformation; Protein Engineering; Time Factors

2004
Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors.
    Biochemistry, 2007, Jul-24, Volume: 46, Issue:29

    Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Crystallography, X-Ray; Enzyme Inhibitors; Glycine; Penicillanic Acid; Serine; Spectrum Analysis, Raman; Stereoisomerism; Tazobactam

2007
Two plate-based colorimetric assays for screening α-amino acid ester hydrolase with high synthesis/hydrolysis ratio.
    Enzyme and microbial technology, 2012, Jul-15, Volume: 51, Issue:2

    Topics: Acinetobacter; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactams; Carboxylic Ester Hydrolases; Catalytic Domain; Cefaclor; Colorimetry; DNA, Bacterial; Enzyme Assays; Glycine; Hydrolysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Engineering; Recombinant Proteins; Xanthomonas

2012
Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-β-lactamase active site.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:11

    Topics: Amino Acid Substitution; beta-Lactamases; beta-Lactams; Catalytic Domain; Cysteine; Escherichia coli; Glycine; Kinetics; Ligands; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis; Protein Binding; Recombinant Proteins; Water; Zinc

2012
Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins.
    ACS infectious diseases, 2018, 10-12, Volume: 4, Issue:10

    Topics: Anti-Bacterial Agents; beta-Lactams; Cations; Cell Membrane Permeability; Crystallography, X-Ray; Enterobacteriaceae; Facilitated Diffusion; Glycine; Libraries, Digital; Liposomes; Osmolar Concentration; Porins; Protein Multimerization; Static Electricity

2018