Page last updated: 2024-09-04

beta-lactams and fropenem

beta-lactams has been researched along with fropenem in 112 studies

Compound Research Comparison

Studies (beta-lactams)	Trials (beta-lactams)	Recent Studies (post-2010) (beta-lactams)	Studies (fropenem)	Trials (fropenem)	Recent Studies (post-2010) (fropenem)
7,579	179	3,395	140	13	52

Research

Studies (112)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	11 (9.82)	18.2507
2000's	64 (57.14)	29.6817
2010's	30 (26.79)	24.3611
2020's	7 (6.25)	2.80

Authors

Authors	Studies
Andrews, JM; Boswell, FJ; Wise, R	1
Akita, H; Goshima, T; Ishihara, T; Iwai, N; Iwata, S; Kanemura, H; Kato, T; Kusumoto, Y; Meguro, H; Nakamura, H; Nakashima, M; Satoh, Y; Sunakawa, K; Terashima, I; Toyonaga, Y; Yokota, T	1
Fujioka, T; Hasegawa, M; Igari, J; Kobayashi, I; Matsuzaki, K; Nasu, M; Saika, T; Saionji, K	1
Arata, J; Moritono, S; Saito, A	1
Hikida, M; Igarashi, A; Itahashi, K; Kitamura, M; Shiba, T	1
Hasegawa, M; Kaneko, A; Kobayashi, I; Matsuzaki, K; Nishiyama, T; Sasaki, J	1
Kakizaki, S; Mori, M; Sato, K; Sato, N; Shimizu, H; Takagi, H; Takahashi, H; Takayama, H; Tsutiya, T	1
Akatsuka, K; Chimura, T; Funayama, T; Hayashi, Y; Hirayama, T; Kaneko, N; Morisaki, N; Murayama, K; Numazaki, M; Oda, T; Sato, F	1
Abe, T; Domon, H; Fukuoka, T; Ishii, C; Kakuta, M; Kawada, H; Kitayama, A; Ohya, S; Utsui, Y	1
Nakanishi, T; Nasu, T; Nishino, T; Okamoto, K	1
China, K; Miyamoto, K; Takeda, E; Tamai, I; Tsuji, A; Uchino, H; Yabuuchi, H	1
Hanaki, H; Hiramatsu, K; Inaba, Y	1
Hasegawa, M; Kobayashi, I; Koyama, H; Matsuzaki, K; Nishiyama, T; Saika, T	1
Nishino, T; Oh, T; Okuda, J; Otsuki, M	1
Gotoh, N; Nishino, T; Okamoto, K	1
Boos, M; Fluit, AC; Mayer, S; Milatovic, D; Schmitz, FJ; Verhoef, J	2
Banzai, M; Chimura, T; Sato, S; Satou, S; Yamakawa, M	1
Furumoto, H; Mikami, Y; Sasaki, T; Shimizu, T; Tatebayashi, K	1
Ishiguro, M; Nishihara, T; Tanaka, R	1
Critchley, IA; Draghi, DC; Jones, ME; Karlowsky, JA; Murfitt, K; Sahm, DF; Thornsberry, C	1
Capper, TP; du Plessis, M; Klugman, KP	1
Mitsuno, Y; Yoshida, H	1
Haruta, T; Kobayashi, KI; Kubota, M; Nishio, T	1
Peters, G; Schepers, S; von Eiff, C	1
Fluit, AC; Milatovic, D; Schmitz, FJ; Verhoef, J	1
Citron, DM; Fernandez, HT; Goldstein, EJ; Merriam, CV; Tyrrell, KL; Warren, YA	1
Karasawa, T; Kuriyama, T; Nakagawa, K; Nakamura, S; Yamamoto, E	1
Andrews, JM; Ashby, JP; Boswell, FJ; Wise, R	1
Amitani, R; Kimoto, T; Suzuki, K; Tanaka, E; Tsuyuguchi, K	1
Finegold, SM; Molitoris, D; Read, EK; St John, S; Vu, A; Wexler, HM	1
Blosser-Middleton, RS; Critchley, IA; Jones, ME; Karlowsky, JA; Sahm, DF; Thornsberry, C	1
Fujimoto, N; Iihara, K; Inatomi, H; Kobayashi, T; Matsumoto, T; Muratani, T; Nishimura, T; Takahashi, K; Yamada, Y	1
Blandino, G; Caccamo, F; Milazzo, I; Musumeci, R; Nicoletti, G; Speciale, A	1
Odagiri, S; Shimada, J; Takahashi, H; Watanuki, Y	1
Sakata, H	1
Ichimaru, T	1
Alefelder, M; Arvis, P; Berg, O; Gehanno, P; Leiberman, A; Martinkenas, JL; Nikolaidis, P; Reimnitz, P; Siegert, R	1
Appelbaum, PC; Credito, KL; Jacobs, MR	1
Amyes, AK; Amyes, SG; Walsh, F	1
Dalhoff, A; Nasu, T; Okamoto, K	2
Johnson, MM; Piddock, LJ; Webber, MA	1
Allouch, PY; Decousser, JW; Picot, F; Pina, P	1
Hamilton-Miller, JM	1
Harigae, H; Ishikawa, S; Kaku, M; Kanemitsu, K; Kunishima, H; Saga, T; Takemura, H	1
Bowker, K; MacGowan, A	1
Dower, SK; Moore, LJ; Pridmore, AC; Read, RC	1
Cars, O; Gustafsson, I	1
Hosaka, Y; Inoue, M; Kaieda, S; Okamoto, R; Okitsu, N; Takahashi, H; Yano, H	1
Kobayashi, C; Sakai, T; Shinohara, M	1
Behra-Miellet, J; Bryskier, A; Dubreuil, L	1
Critchley, IA; Janjic, N; Jones, RN; Pottumarthy, S; Whittington, WL	1
Kandikere, VN; Mudigonda, K; Nirogi, RV; Shrivastava, W	1
Dalziel, C	1
Echols, R; Kowalsky, S; Rosemore, M; Tosiello, R; Upchurch, J	1
Echols, RM; Hadley, JA; Tillotson, GS; Tosiello, R	1
Hope, R; Livermore, DM; Mushtaq, S; Warner, M	1
Arguedas, A; Critchley, IA; Dagan, R; Echols, RM; Janjic, N; Leibovitz, E; Stone, KC; Wang, E	1
Hoban, DJ; Karlowsky, JA; Rubinstein, E; Schurek, KN; Wiebe, R; Zhanel, GG	1
Chen, W; Gao, S; Miao, H; Tao, X; Wu, R; Yang, S	1
Brown, SD; Critchley, IA; Janjic, N; Tillotson, GS; Traczewski, MM	1
Hirata, Y; Kawabe, T; Maeda, S; Mitsuno, Y; Ogura, K; Ohmae, T; Omata, M; Shibata, W; Yanai, A; Yoshida, H	1
Appelbaum, PC; Beachel, L; Clark, C; Credito, K; Dewasse, B; Ednie, L; Kosowska-Shick, K	1
Crank, CW; Gettig, JP; Philbrick, AH	1
Brown, SD; Critchley, IA; Jacobs, MR; Janjic, N; Tillotson, GS; Traczewski, MM	1
Hiraga, N; Matsumoto, T; Muratani, T; Naito, S	1
Appelbaum, PC; Glupczynski, Y; Lemaire, S; Olivier, A; Tulkens, PM; Van Bambeke, F	1
Kobayashi, M; Oda, M; Saitoh, H; Sawazaki, R	1
Bhaumik, U; Bose, A; Chakrabarty, US; Das, A; Ghosh, A; Mandal, U; Pal, TK; Ray, KK	1
Appelbaum, PC; Kosowska-Shick, K; McGhee, P	1
Abe, T; Azagami, S; Bamba, M; Cho, H; Hojo, H; Jozaki, K; Koizumi, Y; Nakao, A; Nonoyama, M; Ojima, T; Ozaki, A; Sunakawa, K; Yokota, T	1
Cabeza, J; Carrasco, C; Gutierrez, J; Sorlozano, A; Villegas, E	1
Gupta, A; Khaira, A; Mahajan, S; Tiwari, SC	1
Fan, G; Wei, H; Wen, J; Xie, R; Zhang, D	1
Ambrose, PG; Bassett, J; Beaudry, A; Bhavnani, SM; Critchley, I; Gill, SC; Heine, HS; Janjic, N; Li, J; Miller, L; Rubino, CM; Stone, KC	1
Hayashi, N; Kawashima, M	1
Katoh, N; Morihara, K; Morihara, T; Takenaka, H	1
Cielecka-Piontek, J; Krause, A; Paczkowska, M	1
Barszcz, B; Cielecka-Piontek, J; Lewandowska, K; Paczkowska, M	1
Barszcz, B; Cielecka-Piontek, J; Czartek, A; Lewandowska, K	1
Cummings, SP; Day, KM; Lanyon, C; Perry, JD; Pike, R; Raza, MW; Winstanley, TG; Woodford, N	1
Cielecka-Piontek, J	1
Arakawa, S; Hamasuna, R; Hayami, H; Kiyota, H; Kobayashi, K; Matsumoto, T; Takahashi, S; Tanaka, K; Yamamoto, S; Yasuda, M	1
Ahn, C; Doi, Y; Hu, F; O'Hara, JA	1
Arthur, M; Ballell, L; Barros, D; Cuinet, G; Dhar, N; Dubée, V; Hugonnet, JE; McKinney, JD; Signorino-Gelo, F	1
Carlson, EE; Kocaoglu, O; Tsui, HC; Winkler, ME	1
Kaushik, A; Lamichhane, G; Makkar, N; Pandey, P; Parrish, N; Singh, U	1
Hara, Y; Haruyama, S; Nakamura, M; Nishio, D; Ohmori, S; Omoto, D; Sakuragi, Y; Sawada, Y; Yoshioka, M	1
Buffet Croix Blanche, S; Canard, I; Charrier, JP; Chatellier, S; Mirande, C; van Belkum, A; Welker, M	1
Fujita, J; Hagihara, M; Hirai, J; Kinjo, T; Mikamo, H; Sakanashi, D; Suematsu, H; Yamagishi, Y	1
Gandra, S; Klein, EY; Laxminarayan, R; Malhotra-Kumar, S; Pant, S	1
Kishimoto, K; Matsuse, H; Nakayama, H; Oshio, T	1
Fujimura, A; Harada, K; Hasegawa, G; Hayasaka, T; Maeda, A; Saito, T; Tsuruoka, S; Ushijima, K	1
Deshpande, D; Gumbo, T; Nuermberger, E; Pasipanodya, JG; Srivastava, S; Swaminathan, S	1
Fujii, S; Fujino, K; Hashimoto, J; Hiyama, Y; Ichihara, K; Masumori, N; Shinagawa, M; Takahashi, S; Uehara, T	1
Schneider, G; Schnell, R; Steiner, EM	1
Gurumurthy, M; Hee, KH; Issac, S; Lee, LS; Lin, W; Lu, Q; Naftalin, CM; Paton, NI; Seng, KY; Tan, A; Tan, KH; Verma, R	1
Bernabeu, S; Dortet, L; Gonzalez, C; Naas, T	1
Cherian, BP; Ciesielczuk, H; Dolphin, H; Phee, LM; Wareham, DW; Wilks, M	1
Bercot, B; de Champs, C; Gautier, G; Guillard, T; Podac, B; Vernet-Garnier, V	1
Chugh, S; Sardana, K	1
Dias, MVB; Dos Santos Silva, C; Libreros-Zúñiga, GA; Salgado Ferreira, R	1
Fukushima, Y; Hiyama, Y; Masumori, N; Nakajima, C; Sato, T; Shinagawa, M; Suzuki, Y; Takahashi, S; Yokota, SI	1
Huang, Q; Li, L; Ma, P; Qi, X; Song, Q; Tao, L; Wei, J; Xing, X; Zhou, G; Zou, B	1
Choi, J; Dantas, G; Das, S; Gandra, S; Green, SJ; Harazin, M; McElvania, E; Singh, KS; Thomson, RB	1
Guddat, L; Liu, X; Lu, Z; Rao, Z; Schofield, CJ; Wang, H; Yang, C; Yang, H; Zhang, A; Zhou, W	1
Fukui, M; Marumo, S; Shirata, M; Tamai, K; Yoshimoto, Y	1
Drobniewski, F; Gonzalo, X; McHugh, TD; Ortiz Canseco, J; Satta, G	1
Abe, K; Furukawa, K; Ito, J; Kawai, F; Matsuo, T; Mikami, Y; Mizuno, A; Mori, N; Ohkushi, D; Sakurai, A; Starkey, J; Uehara, Y; Yamasaki, M; Yoshino, K	1
Armistead, T; Brem, J; Calvopiña, K; Hinchliffe, P; Lohans, CT; Lucic, A; Malla, TR; McDonough, MA; Orville, AM; Rabe, P; Schofield, CJ; Spencer, J; Tooke, CL	1

Reviews

8 review(s) available for beta-lactams and fropenem

Article	Year
[New orally active penem antibiotic: Farom]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2001, Volume: 121, Issue:12 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Design; Escherichia coli; Lactams; Molecular Structure	2001
Chemical and microbiologic aspects of penems, a distinct class of beta-lactams: focus on faropenem. Pharmacotherapy, 2003, Volume: 23, Issue:11 Topics: Animals; beta-Lactams; Drug Resistance, Microbial; Humans; Lactams	2003
Faropenem medoxomil: a treatment option in acute bacterial rhinosinusitis. Expert review of anti-infective therapy, 2006, Volume: 4, Issue:6 Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Middle Aged; Sinusitis; Streptococcus pneumoniae; United States	2006
Faropenem: review of a new oral penem. Expert review of anti-infective therapy, 2007, Volume: 5, Issue:2 Topics: Administration, Oral; Animals; Bacterial Infections; beta-Lactams; Humans	2007
Faropenem medoxomil. The Annals of pharmacotherapy, 2008, Volume: 42, Issue:1 Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; beta-Lactam Resistance; beta-Lactams; Humans; Microbial Sensitivity Tests; Randomized Controlled Trials as Topic; Time Factors	2008
Faropenem medoxomil: A0026, BAY 56-6854, BAY 566854, faropenem daloxate, SUN 208, SUN A0026. Drugs in R&D, 2008, Volume: 9, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Clinical Trials as Topic; Drug Interactions; Humans; Prodrugs	2008
Osteomyelitis caused by Veillonella species: Case report and review of the literature. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2016, Volume: 22, Issue:6 Topics: Adult; beta-Lactams; Debridement; Drug Therapy, Combination; Fluoroquinolones; Gram-Negative Bacterial Infections; Humans; Male; Microbial Sensitivity Tests; Osteomyelitis; Veillonella	2016
Infected aortic aneurysm caused by Helicobacter cinaedi: case series and systematic review of the literature. BMC infectious diseases, 2020, Nov-17, Volume: 20, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Infected; Anti-Bacterial Agents; Aortic Aneurysm; beta-Lactams; Blood Culture; Female; Follow-Up Studies; Helicobacter; Helicobacter Infections; Humans; Immunocompromised Host; Japan; Male; Middle Aged; RNA, Ribosomal, 16S; Tomography, X-Ray Computed; Treatment Outcome	2020

Trials

11 trial(s) available for beta-lactams and fropenem

Article	Year
[Clinical evaluation of faropenem against infections in pediatric fields]. The Japanese journal of antibiotics, 1997, Volume: 50, Issue:9 Topics: Adolescent; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Diarrhea; Dosage Forms; Drug Therapy, Combination; Female; Humans; Infant; Lactams; Male; Penicillin Resistance; Pneumococcal Infections; Respiratory Tract Infections	1997
[Clinical studies of faropenem in the field of obstetrics and gynecology]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:7 Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cystitis; Female; Genital Diseases, Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Lactams; Mastitis; Middle Aged; Pelvic Inflammatory Disease; Uterine Cervicitis; Uterine Diseases	1999
[Triple therapy with faropenem, proton pump inhibitor (PPI), and amoxicillin for clarithromycin-resistant H. pylori eradication]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Amoxicillin; Anti-Bacterial Agents; beta-Lactams; Clarithromycin; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Enzyme Inhibitors; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lactams; Lansoprazole; Male; Middle Aged; Omeprazole; Proton Pump Inhibitors; Treatment Outcome	2002
[Faropenem 300 mg 3 times daily versus levofloxacin 100 mg 3 times daily in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2002, Volume: 76, Issue:11 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; beta-Lactams; Drug Administration Schedule; Female; Humans; Lactams; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostatic Hyperplasia; Urinary Bladder, Neurogenic; Urinary Tract Infections	2002
Comparison of the efficacy and safety of faropenem daloxate and cefuroxime axetil for the treatment of acute bacterial maxillary sinusitis in adults. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2003, Volume: 260, Issue:4 Topics: Acute Disease; Adult; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cefuroxime; Double-Blind Method; Female; Humans; Lactams; Male; Maxillary Sinusitis; Middle Aged; Prospective Studies; Treatment Outcome	2003
Randomized double-blind study comparing 7- and 10-day regimens of faropenem medoxomil with a 10-day cefuroxime axetil regimen for treatment of acute bacterial sinusitis. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2006, Volume: 135, Issue:4 Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cefuroxime; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Prospective Studies; Sinusitis; Time Factors	2006
Efficacy and safety of faropenem in eradication therapy of Helicobacter pylori. Helicobacter, 2007, Volume: 12, Issue:6 Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Microbial Sensitivity Tests; Middle Aged	2007
High-throughput determination of faropenem in human plasma and urine by on-line solid-phase extraction coupled to high-performance liquid chromatography with UV detection and its application to the pharmacokinetic study. Journal of pharmaceutical and biomedical analysis, 2010, May-01, Volume: 52, Issue:1 Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Asian People; Automation, Laboratory; beta-Lactams; Calibration; China; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; Female; High-Throughput Screening Assays; Humans; Hydrogen-Ion Concentration; Male; Online Systems; Reference Standards; Reproducibility of Results; Solid Phase Extraction; Spectrophotometry, Ultraviolet; Young Adult	2010
Efficacy of oral antibiotics on acne vulgaris and their effects on quality of life: a multicenter randomized controlled trial using minocycline, roxithromycin and faropenem. The Journal of dermatology, 2011, Volume: 38, Issue:2 Topics: Acne Vulgaris; Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; beta-Lactams; Female; Humans; Male; Microbial Sensitivity Tests; Minocycline; Patient Satisfaction; Propionibacterium acnes; Quality of Life; Roxithromycin; Treatment Outcome; Young Adult	2011
Treatment of acute uncomplicated cystitis with faropenem for 3 days versus 7 days: multicentre, randomized, open-label, controlled trial. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactams; Cystitis; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Time Factors; Treatment Outcome; Young Adult	2014
Activity of faropenem with and without rifampicin against Mycobacterium tuberculosis: evaluation in a whole-blood bactericidal activity trial. The Journal of antimicrobial chemotherapy, 2017, 07-01, Volume: 72, Issue:7 Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactams; Drug Combinations; Drug Synergism; Female; Healthy Volunteers; Humans; Male; Mycobacterium tuberculosis; Rifampin; Serum Bactericidal Test; Young Adult	2017

Other Studies

93 other study(ies) available for beta-lactams and fropenem

Article	Year
Pharmacodynamic properties of faropenem demonstrated by studies of time-kill kinetics and postantibiotic effect. The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:3 Topics: Anti-Bacterial Agents; Bacteroides fragilis; beta-Lactams; Escherichia coli; Haemophilus influenzae; Kinetics; Lactams; Microbial Sensitivity Tests; Moraxella catarrhalis; Staphylococcus aureus; Streptococcus pyogenes; Time Factors	1997
[In vitro activities of faropenem against clarithromycin resistance Helicobacter pylori isolates]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1998, Volume: 72, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactams; Clarithromycin; Drug Resistance, Microbial; Helicobacter pylori; Humans; Lactams	1998
[Significant role of penem antibiotics: focused on faropenem (discussion)]. The Japanese journal of antibiotics, 1997, Volume: 50, Issue:7 Topics: Anti-Bacterial Agents; Bacteria; beta-Lactams; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Lactams; Respiratory Tract Infections; Skin Diseases, Bacterial; Urinary Tract Infections	1997
In vitro antibacterial activity of LJC 11,036, an active metabolite of L-084, a new oral carbapenem antibiotic with potent antipneumococcal activity. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:8 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Carrier Proteins; Cefdinir; Cephalosporins; Dipeptidases; Drug Stability; Escherichia coli Proteins; Hexosyltransferases; Imipenem; Lactams; Levofloxacin; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Ofloxacin; Penicillin-Binding Proteins; Peptidoglycan Glycosyltransferase; Peptidyl Transferases; Protein Binding; Serine-Type D-Ala-D-Ala Carboxypeptidase; Thienamycins	1999
[In vitro bactericidal activities of new oral penem, faropenem against the various clinical isolates]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactams; Escherichia coli; Haemophilus influenzae; Klebsiella pneumoniae; Lactams; Methicillin Resistance; Microbial Sensitivity Tests; Penicillin Resistance; Peptostreptococcus; Staphylococcus aureus; Streptococcus pneumoniae	1999
Faropenem enhances superoxide anion production by human neutrophils in vitro. The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactams; Calcium; Dose-Response Relationship, Drug; Firefly Luciferin; Humans; Ionomycin; Lactams; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Time Factors	1999
[In vitro and in vivo activities of cefpodoxime proxetil against penicillin-resistant Streptococcus pneumoniae]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:8 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Cefdinir; Cefpodoxime Proxetil; Ceftizoxime; Cephalosporins; Lactams; Male; Mice; Microbial Sensitivity Tests; Penicillin Resistance; Pneumonia, Pneumococcal; Prodrugs; Streptococcus pneumoniae	1999
[In vitro antibacterial activity of faropenem, a novel oral penem antibiotic, against enterohemorrhagic Escherichia coli O157 strains]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:8 Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacterial Toxins; beta-Lactams; Cefdinir; Cephalosporins; Clarithromycin; Escherichia coli O157; Fosfomycin; Kanamycin; Lactams; Microbial Sensitivity Tests; Minocycline; Norfloxacin; Shiga Toxin 1	1999
Faropenem transport across the renal epithelial luminal membrane via inorganic phosphate transporter Npt1. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Carrier Proteins; Cell Membrane; Dose-Response Relationship, Drug; Epithelial Cells; Kidney; Kinetics; Lactams; Mice; Oocytes; Phosphate-Binding Proteins; Phosphates; Xenopus	2000
[Investigation of the antibacterial activity of faropenem against Streptococcus pneumoniae]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; beta-Lactams; Cefaclor; Cephalosporins; Drug Resistance, Microbial; Lactams; Penicillin G; Penicillin Resistance; Streptococcus pneumoniae	1999
[In vitro activity of faropenem against beta-lactamase producing clinical isolates]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:3 Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamases; beta-Lactams; Cefdinir; Cephalosporins; Drug Resistance, Microbial; Humans; Lactams; Microbial Sensitivity Tests	2000
In vitro activity of DU-6681a, an active form of the new oral carbapenem compound DZ-2640, in comparison with that of R-95867, faropenem and oral cephalosporins. The Journal of antimicrobial chemotherapy, 2000, Volume: 46, Issue:1 Topics: Administration, Oral; Anti-Bacterial Agents; Bacteria; beta-Lactams; Carbapenems; Cephalosporins; Lactams; Microbial Sensitivity Tests	2000
Pseudomonas aeruginosa reveals high intrinsic resistance to penem antibiotics: penem resistance mechanisms and their interplay. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:7 Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Biological Transport; Carbapenems; Carrier Proteins; Escherichia coli; Humans; Lactams; Membrane Transport Proteins; Microbial Sensitivity Tests; Porins; Pseudomonas aeruginosa	2001
In vitro activity of faropenem and 21 other compounds against 385 different genetically characterized isolates of antibiotic-resistant Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Resistance, Microbial; Lactams; Microbial Sensitivity Tests; Streptococcus pneumoniae	2001
[Pyogenic sacroiliitis in pregnancy]. The Japanese journal of antibiotics, 2001, Volume: 54, Issue:9 Topics: Adult; Anti-Bacterial Agents; Arthritis, Infectious; beta-Lactams; Female; Humans; Lactams; Meropenem; Pregnancy; Pregnancy Complications, Infectious; Sacroiliac Joint; Suppuration; Thienamycins	2001
Profound skin infection with bone involvement due to Nocardia asteroides in a patient with myelodysplastic syndrome. The Journal of dermatology, 2001, Volume: 28, Issue:10 Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactams; Bone Diseases, Infectious; Female; Foot; Humans; Lactams; Magnetic Resonance Imaging; Myelodysplastic Syndromes; Nocardia asteroides; Nocardia Infections; Skin Diseases, Bacterial	2001
In vitro activity of faropenem and 20 other compounds against beta-lactamase-positive and -negative Moraxella catarrhalis and Haemophilus influenzae isolates and the effect of serum on faropenem MICs. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Haemophilus influenzae; Humans; Lactams; Microbial Sensitivity Tests; Moraxella catarrhalis	2002
Activities of faropenem, an oral beta-lactam, against recent U.S. isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Haemophilus influenzae; Humans; Lactams; Microbial Sensitivity Tests; Moraxella catarrhalis; Streptococcus pneumoniae; United States	2002
In vitro activity of faropenem against respiratory pathogens. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactams; Haemophilus influenzae; Humans; Lactams; Microbial Sensitivity Tests; Moraxella catarrhalis; Respiratory Tract Infections; Streptococcus pneumoniae	2002
A case of retropharyngeal abscess caused by penicillin-resistant Streptococcus pneumoniae. The Journal of infection, 2002, Volume: 44, Issue:4 Topics: Abscess; Anti-Bacterial Agents; beta-Alanine; beta-Lactams; Biopsy, Needle; Drug Therapy, Combination; Female; Humans; Infant; Lactams; Penicillin Resistance; Penicillins; Pharynx; Pneumococcal Infections; Streptococcus pneumoniae; Thienamycins	2002
Comparative in vitro activity of faropenem against staphylococci. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Humans; Lactams; Microbial Sensitivity Tests; Staphylococcus aureus	2002
In vitro activity of faropenem against 5460 clinical bacterial isolates from Europe. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:2 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; beta-Lactams; Europe; Humans; Lactams; Microbial Sensitivity Tests	2002
Comparative in vitro activity of faropenem and 11 other antimicrobial agents against 405 aerobic and anaerobic pathogens isolated from skin and soft tissue infections from animal and human bites. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:3 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; beta-Lactams; Bites and Stings; Fluoroquinolones; Humans; Lactams; Macrolides; Skin Diseases, Bacterial; Tetracyclines	2002
Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics. Oral microbiology and immunology, 2002, Volume: 17, Issue:5 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacteroidaceae Infections; beta-Lactams; Cefepime; Cefmetazole; Cefoperazone; Cefpirome; Ceftazidime; Ceftizoxime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Fusobacterium; Fusobacterium Infections; Gram-Positive Bacterial Infections; Humans; Imipenem; Lactams; Microbial Sensitivity Tests; Mouth Diseases; Penicillin G; Penicillins; Peptostreptococcus; Porphyromonas gingivalis; Prevotella; Streptococcal Infections; Streptococcus; Sulbactam	2002
Effect of protein binding on the in vitro activity and pharmacodynamics of faropenem. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:4 Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactams; Humans; Lactams; Microbial Sensitivity Tests; Protein Binding; Serum Albumin; Staphylococcus aureus	2002
Successful treatment with faropenem and clarithromycin of pulmonary Mycobacterium abscessus infection. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2002, Volume: 8, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactams; Clarithromycin; Drug Therapy, Combination; Humans; Lactams; Lung Diseases; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium Infections, Nontuberculous	2002
In vitro activities of faropenem against 579 strains of anaerobic bacteria. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:11 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Proteins; beta-Lactamases; beta-Lactams; DNA, Bacterial; Drug Resistance, Bacterial; Lactams; Microbial Sensitivity Tests; Reverse Transcriptase Polymerase Chain Reaction	2002
Activity of faropenem, a new furanem, against European respiratory pathogens collected during 2000-2001: a comparison with other beta-lactam agents. The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Resistance, Bacterial; Europe; Haemophilus influenzae; Humans; Lactams; Microbial Sensitivity Tests; Moraxella catarrhalis; Respiratory Tract Infections; Streptococcus pneumoniae	2003
Faropenem, a new oral penem: antibacterial activity against selected anaerobic and fastidious periodontal isolates. The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:3 Topics: Administration, Oral; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; beta-Lactams; Humans; Lactams; Mouth; Periodontal Diseases	2003
[Epidemiological study on patients with pneumococcal respiratory tract infection in a Japanese health facility during the past year]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Chronic Disease; Clarithromycin; Community-Acquired Infections; Drug Therapy, Combination; Female; Humans; Lactams; Male; Middle Aged; Ofloxacin; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae; Time Factors	2001
[Comparative study on bacterial eradication rate and clinical efficacy of CDTR, CFPN, and FRPM for treatment of children with otitis media and lower respiratory tract infection due to Streptococcus pneumoniae and Haemophilus influenzae]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Ampicillin Resistance; Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Child; Child, Preschool; Community-Acquired Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Lactams; Otitis Media; Penicillin Resistance; Pneumococcal Infections; Respiratory Tract Infections; Retrospective Studies; Streptococcus pneumoniae; Treatment Outcome	2001
[Study on Streptococcus pneumoniae isolated from infants in widely-separated primary care facilities in Japan]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Child Day Care Centers; Child, Preschool; Drug Resistance, Bacterial; Humans; Infant; Japan; Lactams; Otitis Media; Penicillin G; Serotyping; Siblings; Streptococcus pneumoniae	2001
In vitro activity of faropenem compared with eight agents against fourteen Gram-positive and Gram-negative bacteria by time-kill. The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:6 Topics: Anti-Infective Agents; beta-Lactams; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Lactams; Microbial Sensitivity Tests	2003
The in vitro effects of faropenem on lower respiratory tract pathogens isolated in the United Kingdom. International journal of antimicrobial agents, 2003, Volume: 21, Issue:6 Topics: Anti-Bacterial Agents; beta-Lactams; Haemophilus influenzae; Lactams; Microbial Sensitivity Tests; Moraxella catarrhalis; Respiratory Tract Infections; Streptococcus pneumoniae; United Kingdom	2003
Target affinities of faropenem to and its impact on the morphology of gram-positive and gram-negative bacteria. Chemotherapy, 2003, Volume: 49, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Binding Sites; Carrier Proteins; Cefuroxime; Dose-Response Relationship, Drug; Enterobacteriaceae; Enzyme Stability; Escherichia coli Proteins; Gram-Positive Cocci; Hexosyltransferases; Imipenem; In Vitro Techniques; Lactams; Microscopy, Electron, Scanning; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidoglycan Glycosyltransferase; Peptidyl Transferases; Serine-Type D-Ala-D-Ala Carboxypeptidase	2003
Activity of faropenem and imipenem for ciprofloxacin-resistant bacteria. The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:3 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; beta-Lactams; Ciprofloxacin; Drug Resistance, Bacterial; Humans; Imipenem; Lactams; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Thienamycins	2003
Comparative in vitro activity of faropenem and 11 other antimicrobial agents against 250 invasive Streptococcus pneumoniae isolates from France. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2003, Volume: 22, Issue:9 Topics: Anti-Bacterial Agents; Bacteremia; beta-Lactams; Child; Child, Preschool; Drug Resistance, Microbial; France; Humans; Infant; Lactams; Microbial Sensitivity Tests; Pneumococcal Infections; Sampling Studies; Sensitivity and Specificity; Streptococcus pneumoniae	2003
Beta-lactamase stability of faropenem. Chemotherapy, 2003, Volume: 49, Issue:5 Topics: Anti-Bacterial Agents; Bacteria, Aerobic; beta-Lactamases; beta-Lactams; Drug Resistance, Microbial; Drug Stability; Hydrolysis; Lactams; Microbial Sensitivity Tests	2003
Efficacy of amikacin combinations for nocardiosis. The Tohoku journal of experimental medicine, 2003, Volume: 201, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; beta-Lactams; Cefotaxime; Ciprofloxacin; DNA, Ribosomal; Drug Therapy, Combination; Erythromycin; Female; Fluoroquinolones; Gram-Positive Bacteria; Humans; Imipenem; Lactams; Male; Middle Aged; Minocycline; Nocardia; Nocardia Infections; RNA, Ribosomal, 16S; Streptomyces; Sulfamethoxazole; Trimethoprim	2003
In vitro studies on the impact of human serum on the antibacterial effect of faropenem. Journal of chemotherapy (Florence, Italy), 2004, Volume: 16, Issue:1 Topics: beta-Lactams; Haemophilus influenzae; Humans; Lactams; Microbial Sensitivity Tests; Protein Binding; Serum; Staphylococcus aureus; Streptococcus pneumoniae	2004
The glycopeptide vancomycin does not enhance toll-like receptor 2 (TLR2) activation by Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactams; Cefotaxime; Cell Wall; Cephalosporins; Genes, Reporter; HeLa Cells; Humans; Interleukin-8; Lactams; Lipopolysaccharide Receptors; Luciferases; Membrane Glycoproteins; Microbial Sensitivity Tests; Plasmids; Receptors, Cell Surface; Streptococcus pneumoniae; Toll-Like Receptor 2; Toll-Like Receptors; Transfection; Vancomycin	2004
The influence of protein binding on the antibacterial activity of faropenem against Haemophilus influenzae. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2004, Volume: 10, Issue:10 Topics: beta-Lactamases; beta-Lactams; Carbapenems; Colony Count, Microbial; Haemophilus Infections; Haemophilus influenzae; Humans; Lactams; Microbial Sensitivity Tests; Protein Binding; Serum Albumin; Serum Bactericidal Test	2004
In vitro investigation of the indirect pathogenicity of beta-lactamase-producing microorganisms in the nasopharyngeal microflora. International journal of pediatric otorhinolaryngology, 2005, Volume: 69, Issue:4 Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefaclor; Ceftriaxone; Dose-Response Relationship, Drug; Haemophilus paragallinarum; Imipenem; Lactams; Microbial Sensitivity Tests; Moraxella catarrhalis; Penicillins; Time Factors	2005
Mycobacterium peregrinum infection in a patient with AIDS. Internal medicine (Tokyo, Japan), 2005, Volume: 44, Issue:3 Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; beta-Lactams; Clarithromycin; Drug Therapy, Combination; Female; Follow-Up Studies; HIV; Humans; Imipenem; Lactams; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; RNA, Viral	2005
In vitro evaluation of faropenem activity against anaerobic bacteria. Journal of chemotherapy (Florence, Italy), 2005, Volume: 17, Issue:1 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; beta-Lactams; Humans; In Vitro Techniques; Lactams; Microbial Sensitivity Tests	2005
Activity of faropenem tested against Neisseria gonorrhoeae isolates including fluoroquinolone-resistant strains. Diagnostic microbiology and infectious disease, 2005, Volume: 53, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactams; Cysteine; Drug Antagonism; Drug Resistance, Bacterial; Fluoroquinolones; Gonorrhea; Humans; Lactams; Microbial Sensitivity Tests; Neisseria gonorrhoeae; United States	2005
Quantification of faropenem in human plasma by high-performance liquid chromatography. Arzneimittel-Forschung, 2005, Volume: 55, Issue:12 Topics: beta-Lactams; Calibration; Chromatography, High Pressure Liquid; Humans; Lactams; Quality Control; Reproducibility of Results; Spectrophotometry, Ultraviolet; Therapeutic Equivalency	2005
JPMorgan 24th Annual Healthcare Conference. IDrugs : the investigational drugs journal, 2006, Volume: 9, Issue:3 Topics: Anti-Bacterial Agents; Antineoplastic Agents; beta-Lactams; Cholecalciferol; Clinical Trials as Topic; Delivery of Health Care; Drug Industry; HSP90 Heat-Shock Proteins; Humans; Multiple Myeloma; Urologic Diseases; Vitamins	2006
Activity of faropenem against cephalosporin-resistant Enterobacteriaceae. The Journal of antimicrobial chemotherapy, 2007, Volume: 59, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactams; Cephalosporin Resistance; England; Enterobacteriaceae; Humans; Microbial Sensitivity Tests	2007
Activity of faropenem against middle ear fluid pathogens from children with acute otitis media in Costa Rica and Israel. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Acute Disease; Anti-Bacterial Agents; beta-Lactams; Child; Costa Rica; Ear, Middle; Haemophilus influenzae; Humans; Israel; Microbial Sensitivity Tests; Moraxella catarrhalis; Otitis Media with Effusion; Streptococcus pneumoniae; Streptococcus pyogenes	2007
Determination of faropenem in human plasma and urine by liquid chromatography-tandem mass spectrometry. Biomedical chromatography : BMC, 2008, Volume: 22, Issue:1 Topics: Acetonitriles; beta-Lactams; Calibration; Cephalexin; Chromatography, High Pressure Liquid; Feasibility Studies; Formates; Humans; Hydrophobic and Hydrophilic Interactions; Methanol; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2008
National and regional assessment of antimicrobial resistance among community-acquired respiratory tract pathogens identified in a 2005-2006 U.S. Faropenem surveillance study. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Infections; beta-Lactams; Community-Acquired Infections; Drug Resistance, Multiple, Bacterial; Geography; Haemophilus influenzae; Health Surveys; Humans; Moraxella catarrhalis; Penicillin Resistance; Respiratory Tract Infections; Streptococcus pneumoniae; Trimethoprim, Sulfamethoxazole Drug Combination; United States	2007
In vitro capability of faropenem to select for resistant mutants of Streptococcus pneumoniae and Haemophilus influenzae. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Resistance, Bacterial; Haemophilus influenzae; Humans; Ketolides; Macrolides; Mutation; Quinolones; Selection, Genetic; Serial Passage; Streptococcus pneumoniae	2008
Prevalence of serotype 19A Streptococcus pneumoniae among isolates from U.S. children in 2005-2006 and activity of faropenem. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Adolescent; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Drug Resistance, Bacterial; Humans; Infant; Microbial Sensitivity Tests; Phenotype; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; United States	2008
Genetic analysis of faropenem-resistant Enterococcus faecalis in urinary isolates. The Journal of antibiotics, 2008, Volume: 61, Issue:4 Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Electrophoresis, Gel, Pulsed-Field; Enterococcus faecalis; Genotype; Humans; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Urinary Tract Infections	2008
Restoration of susceptibility of intracellular methicillin-resistant Staphylococcus aureus to beta-lactams: comparison of strains, cells, and antibiotics. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cefepime; Cefuroxime; Cell Line; Cells, Cultured; Cephalosporins; Cloxacillin; Humans; Hydrogen-Ion Concentration; Imipenem; Meropenem; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Oxacillin; Phagocytosis; Staphylococcus aureus; Thienamycins	2008
Region-dependent absorption of faropenem shared with foscarnet, a phosphate transporter substrate, in the rat small intestine. International journal of antimicrobial agents, 2008, Volume: 32, Issue:3 Topics: Animals; Antiviral Agents; beta-Lactams; Foscarnet; Intestinal Absorption; Intestine, Small; Male; Phosphate Transport Proteins; Rats; Rats, Wistar	2008
Evaluation of the bioequivalence of two faropenem formulations in healthy Indian subjects. Arzneimittel-Forschung, 2008, Volume: 58, Issue:12 Topics: Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; beta-Lactams; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Humans; India; Indicators and Reagents; Male; Middle Aged; Spectrophotometry, Ultraviolet; Therapeutic Equivalency; Young Adult	2008
Binding of faropenem and other beta-lactam agents to penicillin-binding proteins of pneumococci with various beta-lactam susceptibilities. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Penicillin-Binding Proteins; Streptococcus pneumoniae	2009
[Efficacy and safety of faropenem in pediatric patients with bacterial infectious diseases]. The Japanese journal of antibiotics, 2008, Volume: 61, Issue:6 Topics: beta-Lactams; Child; Child, Preschool; Dosage Forms; Drug Resistance, Bacterial; Humans; Otitis Media; Respiratory Tract Infections; Streptococcus pneumoniae; Streptococcus pyogenes; Treatment Outcome; Urinary Tract Infections	2008
Antimicrobial development in the era of emerging resistance. Mini reviews in medicinal chemistry, 2009, Volume: 9, Issue:8 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteria; beta-Lactams; Cephalosporins; Drug Approval; Drug Resistance, Bacterial; Glycopeptides; Humans; Lipoglycopeptides; Pyrimidines; Skin Diseases, Bacterial; Skin Diseases, Viral; Teicoplanin; United States; United States Food and Drug Administration	2009
Pedal oedema: a rare side-effect of faropenem. Nephrology (Carlton, Vic.), 2009, Volume: 14, Issue:7 Topics: beta-Lactams; Edema; Humans	2009
Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Animals; Anthrax; Anti-Bacterial Agents; Bacillus anthracis; beta-Lactamases; beta-Lactams; Blood Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inhalation Exposure; Mice; Mice, Inbred BALB C; Models, Biological	2010
Cutaneous Mycobacterium chelonae infection successfully treated with faropenem. The Journal of dermatology, 2011, Volume: 38, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Humans; Male; Middle Aged; Mycobacterium chelonae; Mycobacterium Infections, Nontuberculous; Skin Diseases, Infectious; Treatment Outcome	2011
An application of high performance liquid chromatographic assay for the kinetic analysis of degradation of faropenem. Die Pharmazie, 2012, Volume: 67, Issue:11 Topics: beta-Lactams; Chromatography, High Pressure Liquid; Drug Compounding; Drug Stability; Hydrochloric Acid; Indicators and Reagents; Kinetics; Reference Standards; Spectrophotometry, Ultraviolet	2012
The use of UV, FT-IR and Raman spectra for the identification of the newest penem analogs: solutions based on mathematic procedure and the density functional theory. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Feb-15, Volume: 103 Topics: beta-Lactams; Carbapenems; Doripenem; Models, Molecular; Quantum Theory; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thienamycins	2013
Solid-state stability studies of faropenem based on chromatography, spectroscopy and theoretical analysis. Drug development and industrial pharmacy, 2014, Volume: 40, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactams; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Humidity; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thermodynamics	2014
Use of faropenem as an indicator of carbapenemase activity in the Enterobacteriaceae. Journal of clinical microbiology, 2013, Volume: 51, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Sensitivity and Specificity; United Kingdom	2013
Derivative spectrophotometry for the determination of faropenem in the presence of degradation products: an application for kinetic studies. Applied spectroscopy, 2013, Volume: 67, Issue:7 Topics: Anti-Bacterial Agents; beta-Lactams; Complex Mixtures; Kinetics; Microchemistry; Spectrophotometry	2013
Faropenem disks for screening of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae. Journal of clinical microbiology, 2014, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Enterobacteriaceae; Humans; Microbial Sensitivity Tests	2014
Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:2 Topics: Antitubercular Agents; beta-Lactams; Isoniazid; Mycobacterium tuberculosis; Peptidyl Transferases	2015
Profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:6 Topics: Amdinocillin; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cephalosporins; Doripenem; Electrophoresis, Polyacrylamide Gel; Meropenem; Penicillin-Binding Proteins; Streptococcus pneumoniae; Thienamycins	2015
Carbapenems and Rifampin Exhibit Synergy against Mycobacterium tuberculosis and Mycobacterium abscessus. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10 Topics: Antitubercular Agents; beta-Lactams; Carbapenems; Doripenem; Drug Synergism; Meropenem; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis; Rifampin; Thienamycins	2015
Acute Generalized Exanthematous Pustulosis Caused by Faropenem: A Possible Pathogenetic Role for Interleukin-23. Acta dermato-venereologica, 2016, Volume: 96, Issue:2 Topics: Acute Generalized Exanthematous Pustulosis; Aged; Anti-Bacterial Agents; beta-Lactams; Biopsy; Drug Eruptions; Female; Humans; Interleukin-23; Skin; Steroids; Treatment Outcome	2016
Rapid detection of carbapenemase activity: benefits and weaknesses of MALDI-TOF MS. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2015, Volume: 34, Issue:11 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Ertapenem; Fungi; Humans; Hydrolysis; Kinetics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors	2015
Faropenem Consumption is Increasing in India. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Apr-15, Volume: 62, Issue:8 Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Drug Resistance, Multiple; Drug Utilization; Humans; India; Microbial Sensitivity Tests	2016
[A CASE OF PULMONARY MYCOBACTERIUM ABSCESSUS INFECTION THAT DEVELOPED DURING IMMUNOSUPPRESSIVE THERAPY FOR MYASTHENIA GRAVIS WITH RECURRENT THYMOMA]. Kekkaku : [Tuberculosis], 2016, Volume: 91, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Clarithromycin; Cyclosporine; Drug Therapy, Combination; Glucocorticoids; Humans; Immunocompromised Host; Immunosuppressive Agents; Levofloxacin; Male; Middle Aged; Myasthenia Gravis; Mycobacterium Infections, Nontuberculous; Neoplasm Recurrence, Local; Thymoma; Thymus Neoplasms; Treatment Outcome	2016
Dialyzability of Faropenem in Infected Patients on Chronic Hemodialysis. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2017, Volume: 21, Issue:1 Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Female; Humans; Infections; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis	2017
A Faropenem, Linezolid, and Moxifloxacin Regimen for Both Drug-Susceptible and Multidrug-Resistant Tuberculosis in Children: FLAME Path on the Milky Way. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Nov-01, Volume: 63, Issue:suppl 3 Topics: Antitubercular Agents; Bacterial Load; beta-Lactams; Child; Computer Simulation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fluoroquinolones; Humans; Linezolid; Microbial Sensitivity Tests; Models, Theoretical; Moxifloxacin; Mycobacterium tuberculosis; Tuberculosis; Tuberculosis, Multidrug-Resistant	2016
The efficacy of faropenem for patients with acute cystitis caused by extended spectrum β-lactamase producing Escherichia coli. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2017, Volume: 23, Issue:5 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cystitis; Escherichia coli; Escherichia coli Infections; Female; Humans; Male; Middle Aged; Retrospective Studies; Young Adult	2017
Binding and processing of β-lactam antibiotics by the transpeptidase Ldt The FEBS journal, 2017, Volume: 284, Issue:5 Topics: beta-Lactams; Carbapenems; Crystallography, X-Ray; Kinetics; Mycobacterium tuberculosis; Peptidoglycan; Peptidyl Transferases; Protein Conformation; Tuberculosis	2017
Comparison of Two Phenotypic Algorithms To Detect Carbapenemase-Producing Enterobacteriaceae. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:8 Topics: Algorithms; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenem-Resistant Enterobacteriaceae; Clavulanic Acids; Disk Diffusion Antimicrobial Tests; Enterobacteriaceae Infections; Humans; Imipenem; Penicillins; Ticarcillin	2017
Optimal detection of carbapenemase-producing Enterobacteriaceae from rectal samples: a role for enrichment? The Journal of hospital infection, 2018, Volume: 98, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenem-Resistant Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Mass Screening; Microbial Sensitivity Tests; Rectum; Retrospective Studies	2018
Detection of different classes of carbapenemases: Adaptation and assessment of a phenotypic method applied to Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter baumannii, and proposal of a new algorithm. Journal of microbiological methods, 2018, Volume: 147 Topics: Acinetobacter baumannii; Algorithms; Bacterial Proteins; Bacteriological Techniques; beta-Lactamases; beta-Lactams; Enterobacteriaceae; Microbial Sensitivity Tests; Molecular Biology; Penicillins; Phenotype; Pseudomonas aeruginosa; Reagent Kits, Diagnostic; Sensitivity and Specificity	2018
Newer therapeutic modalities for Actinomycetoma by Nocardia species. International journal of dermatology, 2018, Volume: 57, Issue:9 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Therapy, Combination; Humans; Linezolid; Male; Microbial Sensitivity Tests; Mycetoma; Trimethoprim, Sulfamethoxazole Drug Combination	2018
Structural Basis for the Interaction and Processing of β-Lactam Antibiotics by l,d-Transpeptidase 3 (Ldt ACS infectious diseases, 2019, 02-08, Volume: 5, Issue:2 Topics: Antitubercular Agents; beta-Lactams; Catalytic Domain; Molecular Docking Simulation; Mycobacterium tuberculosis; Peptidyl Transferases	2019
Evaluation of Susceptibilities to Carbapenems and Faropenem Against Cephalosporin-Resistant Neisseria gonorrhoeae Clinical Isolates with penA Mosaic Alleles. Microbial drug resistance (Larchmont, N.Y.), 2019, Volume: 25, Issue:3 Topics: Alleles; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Carbapenems; Cephalosporin Resistance; Cephalosporins; Humans; Male; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae	2019
Predicting Pharmacokinetics Variation of Faropenem Using a Pharmacometabonomic Approach. Journal of proteome research, 2020, 01-03, Volume: 19, Issue:1 Topics: Animals; beta-Lactams; Chromatography, High Pressure Liquid; Chromatography, Liquid; Metabolomics; Rats; Tandem Mass Spectrometry	2020
Faropenem resistance causes in vitro cross-resistance to carbapenems in ESBL-producing Escherichia coli. International journal of antimicrobial agents, 2020, Volume: 55, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Drug Resistance, Bacterial; Ertapenem; Escherichia coli; Escherichia coli Infections; Humans; Porins	2020
Structures of Molecular pharmacology, 2020, Volume: 97, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Crystallography, X-Ray; Drug Design; Meropenem; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Penicillin-Binding Proteins; Protein Binding; Protein Domains; Recombinant Proteins; Tuberculosis	2020
In vitro efficacy of combinations of eight antimicrobial agents against Mycobacteroides abscessus complex. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020, Volume: 97 Topics: Actinomycetales Infections; Amikacin; Anti-Bacterial Agents; beta-Lactams; Clarithromycin; Doxycycline; Humans; Imipenem; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Mycobacteriaceae; Sequence Analysis, DNA	2020
Ertapenem and Faropenem against Mycobacterium tuberculosis: in vitro testing and comparison by macro and microdilution. BMC microbiology, 2020, 08-31, Volume: 20, Issue:1 Topics: Amoxicillin-Potassium Clavulanate Combination; Antitubercular Agents; beta-Lactams; Drug Resistance, Bacterial; Ertapenem; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis; Tuberculosis, Multidrug-Resistant	2020
Faropenem reacts with serine and metallo-β-lactamases to give multiple products. European journal of medicinal chemistry, 2021, Apr-05, Volume: 215 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Catalytic Domain; Crystallography, X-Ray; Hydrolysis; Klebsiella pneumoniae; Protein Binding; Pseudomonas aeruginosa; Stenotrophomonas maltophilia	2021