beta-lactams has been researched along with ceftobiprole in 14 studies
| Studies (beta-lactams) | Trials (beta-lactams) | Recent Studies (post-2010) (beta-lactams) | Studies (ceftobiprole) | Trials (ceftobiprole) | Recent Studies (post-2010) (ceftobiprole) |
|---|---|---|---|---|---|
| 7,579 | 179 | 3,395 | 212 | 15 | 97 |
| Protein | Taxonomy | beta-lactams (IC50) | ceftobiprole (IC50) |
|---|---|---|---|
| MecA | Staphylococcus aureus | 4.1667 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Georgopapadakou, N | 1 |
| Appelbaum, PC | 1 |
| Livermore, DM | 1 |
| Bush, K; Davies, TA; Shang, W | 1 |
| Appelbaum, PC; Pankuch, GA | 1 |
| Bush, K; Heep, M; Macielag, MJ; Noel, GJ | 1 |
| Archer, G; Cuirolo, A; Faccone, D; Goldstein, F; Kitzis, MD; Ly, A; Morris, J; Perutka, J; Plata, K; Rosato, AE; Sournia, A | 1 |
| Abrahamian, FM; Deblieux, PM; Emerman, CL; Kollef, MH; Kupersmith, E; Leeper, KV; Paterson, DL; Shorr, AF | 1 |
| Cabeza, J; Carrasco, C; Gutierrez, J; Sorlozano, A; Villegas, E | 1 |
| Cattoir, V; Daurel, C | 1 |
| Davies, TA; Flamm, RK; Lynch, AS | 1 |
| Danel, F; de Castro, L; Gretes, MC; Lovering, AL; Page, MG; Safadi, SS; Strynadka, NC | 1 |
| Aedo, S; Alexander, JAN; Basuino, L; Chambers, HF; Chatterjee, SS; Choo, EJ; Chung, M; da Costa, TM; Hamilton, SM; Severin, A; Strynadka, NCJ; Tomasz, A | 1 |
| Gutheil, WG; Sharma, AD | 1 |
5 review(s) available for beta-lactams and ceftobiprole
| Article | Year |
|---|---|
MRSA--the tip of the iceberg.
Topics: Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Community-Acquired Infections; Gram-Positive Bacteria; Humans; Methicillin Resistance; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2006 |
Can beta-lactams be re-engineered to beat MRSA?
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Cephalosporins; Drug Design; Humans; Methicillin Resistance; Staphylococcal Infections; Staphylococcus aureus | 2006 |
Anti-MRSA beta-lactams in development, with a focus on ceftobiprole: the first anti-MRSA beta-lactam to demonstrate clinical efficacy.
Topics: Animals; beta-Lactams; Cephalosporins; Drugs, Investigational; Humans; Methicillin Resistance; Staphylococcal Infections; Sulfhydryl Compounds | 2007 |
Health care-associated pneumonia: identification and initial management in the ED.
Topics: Acetamides; Age Distribution; Aged; Aged, 80 and over; Anti-Infective Agents; beta-Lactams; Cephalosporins; Cross Infection; Emergency Treatment; Ertapenem; Female; Humans; Length of Stay; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Oxazolidinones; Patient Care Team; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Practice Guidelines as Topic; Respiration, Artificial; Risk Factors; Severity of Illness Index; Tigecycline | 2008 |
[Update on antimicrobial chemotherapy].
Topics: Acetamides; Aminoglycosides; Anti-Infective Agents; beta-Lactams; Carbapenems; Cephalosporins; Daptomycin; Doripenem; Drug Resistance, Bacterial; Ertapenem; Fluoroquinolones; France; Humans; Linezolid; Lipoglycopeptides; Minocycline; Oxazolidinones; Penicillins; Pyrimidines; Teicoplanin; Tigecycline | 2010 |
9 other study(ies) available for beta-lactams and ceftobiprole
| Article | Year |
|---|---|
Superbugs and Superdrugs: a focus on antibacterials--6th annual SMi conference.
Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cephalosporins; Clinical Trials as Topic; Daptomycin; Drug Design; Drug Evaluation, Preclinical; Drug Resistance; Drug Resistance, Multiple, Bacterial; Humans; Ketolides; Marketing; Mice; Protein Synthesis Inhibitors; Ribosomes; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2004 |
Activities of ceftobiprole and other beta-lactams against Streptococcus pneumoniae clinical isolates from the United States with defined substitutions in penicillin-binding proteins PBP 1a, PBP 2b, and PBP 2x.
Topics: Amino Acid Motifs; Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactams; Cephalosporins; Humans; Microbial Sensitivity Tests; Mutation; Penicillin-Binding Proteins; Peptidyl Transferases; Streptococcus pneumoniae; United States | 2006 |
Postantibiotic effect of ceftobiprole against 12 Gram-positive organisms.
Topics: Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Enterococcus faecalis; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus pneumoniae | 2006 |
Identification and phenotypic characterization of a beta-lactam-dependent, methicillin-resistant Staphylococcus aureus strain.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Cephalosporins; Chromosomes, Bacterial; DNA-Binding Proteins; DNA, Bacterial; Electrophoresis, Gel, Pulsed-Field; Gene Expression Regulation, Bacterial; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Selection, Genetic; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Staphylococcus aureus; Transcription, Genetic | 2007 |
Antimicrobial development in the era of emerging resistance.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteria; beta-Lactams; Cephalosporins; Drug Approval; Drug Resistance, Bacterial; Glycopeptides; Humans; Lipoglycopeptides; Pyrimidines; Skin Diseases, Bacterial; Skin Diseases, Viral; Teicoplanin; United States; United States Food and Drug Administration | 2009 |
Activity of ceftobiprole against Streptococcus pneumoniae isolates exhibiting high-level resistance to ceftriaxone.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactams; Ceftriaxone; Cephalosporins; Genotype; Humans; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Penicillins; Peptide Synthases; Sequence Analysis, DNA; Streptococcus pneumoniae | 2012 |
Structural insights into the anti-methicillin-resistant Staphylococcus aureus (MRSA) activity of ceftobiprole.
Topics: Anti-Bacterial Agents; beta-Lactams; Calorimetry, Differential Scanning; Catalytic Domain; Cephalosporins; Crystallography, X-Ray; Enzyme Inhibitors; Kinetics; Methicillin-Resistant Staphylococcus aureus; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; Staphylococcal Infections; Staphylococcus aureus | 2012 |
High-Level Resistance of Staphylococcus aureus to β-Lactam Antibiotics Mediated by Penicillin-Binding Protein 4 (PBP4).
Topics: Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Methicillin Resistance; Penicillin-Binding Proteins; Staphylococcal Infections; Staphylococcus aureus | 2017 |
Synergistic Combinations of FDA-Approved Drugs with Ceftobiprole against Methicillin-Resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; beta-Lactams; Ceftaroline; Cloxacillin; Floxacillin; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections | 2023 |