Page last updated: 2024-09-04

beta-lactams and cefepime

beta-lactams has been researched along with cefepime in 63 studies

Compound Research Comparison

Studies (beta-lactams)	Trials (beta-lactams)	Recent Studies (post-2010) (beta-lactams)	Studies (cefepime)	Trials (cefepime)	Recent Studies (post-2010) (cefepime)
7,579	179	3,395	1,737	186	684

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.59)	18.7374
1990's	1 (1.59)	18.2507
2000's	22 (34.92)	29.6817
2010's	28 (44.44)	24.3611
2020's	11 (17.46)	2.80

Authors

Authors	Studies
Lucain, C; Marchou, B; Michea-Hamzehpour, M; Pechère, JC	1
Verbist, L; Verhaegen, J	1
Andre, C; Arpin, C; Dubois, V; Frigo, C; Melon, B; Melon, M; Quentin, C	1
Chen, M; Xu, Y; Zhang, S	1
Beach, ML; Biedenbach, DJ; Jones, RN; Kirby, JT; Pfaller, MA	1
Karasawa, T; Kuriyama, T; Nakagawa, K; Nakamura, S; Yamamoto, E	1
Bethel, CR; Bonomo, RA; Helfand, MS; Hujer, AM	1
Burgess, DS; Hall, RG	1
Lee, WS; Lin, ML; Liu, CY; Wang, FD	1
Kaye, KM; Martin, SI	1
Choe, KW; Kang, CI; Kim, EC; Kim, HB; Kim, SH; Oh, MD; Pai, H	1
Azanza, JR; Campanero, MA; García-Quetglas, E; Sádaba, B	1
Burgess, DS; Frei, CR	1
Dittrich, E; Guttmann, C; Meyer, B; Schmaldienst, S; Thalhammer, F	1
Chuang, YM; Ho, YC; Hsueh, PR; Teng, LJ; Tseng, SP	1
Batard, E; Caillon, J; Kergueris, MF; Le Conte, P; Moreau, P; Navas, D; Potel, G	1
Albertí, S; Alonso, D; Borrell, N; Doménech-Sánchez, A; Gomez, C; Padilla, E; Pérez, JL	1
Satti, F; Shames, R; Smith, MA; Vellozzi, EM	1
Adeyi, B; DiNubile, MJ; Friedland, IR; Ginanni, JA; McCarroll, KA; Stratchounski, LS; Wood, CA; Woods, GL; Yakovlev, SV	1
Koh, TH; Koh, TY; Wang, G	1
Charlier, C; Denooz, R	1
Appelbaum, PC; Glupczynski, Y; Lemaire, S; Olivier, A; Tulkens, PM; Van Bambeke, F	1
Bou, G; Torres, E; Villanueva, R	1
Conejo, Mdel C; Hernández, JR; Pascual, A	1
Lee, HJ; Lee, KM; Suh, JT; Yang, HY	1
De Backer, D; Delattre, I; Dugernier, T; Jacobs, F; Laterre, PF; Layeux, B; Spapen, H; Taccone, FS; Vincent, JL; Wallemacq, P; Wittebole, X	1
Bivas, A; Fraser, A; Leibovici, L; Paul, M; Yahav, D	1
Chumjan, W; Hajjar, E; Mahendran, KR; Schulte, A; Suginta, W; Weingart, H; Winterhalter, M	1
Cabot, G; Juan, C; Mark, BL; Moyá, B; Oliver, A; Reeve, TM; Vocadlo, DJ; Zamorano, L	1
Cotton, F; De Backer, D; Jacobs, F; Macours, P; Seyler, L; Taccone, FS; Vincent, JL	1
Gonçalves-Pereira, J; Póvoa, P	1
Delattre, IK; Jacobs, F; Jacqmin, P; Laterre, PF; Musuamba, FT; Taccone, FS; Verbeeck, RK; Wallemacq, P	1
Beumier, M; Cotton, F; De Backer, D; Hites, M; Jacobs, F; Lorent, S; Roisin, S; Seyler, L; Surin, R; Taccone, FS; Vincent, JL; Wolff, F	1
Arnold, HM; Hampton, NB; Hoban, A; Hoffmann, J; Hollands, JM; Juang, PH; Kollef, MH; McCormick, S; Micek, ST; Reichley, RM; Skrupky, LP; Smith, JR	1
Singh, HL; Singh, RM	1
Blanchette, LM; Kuti, JL; Nailor, MD; Nicolau, DP	1
Cao, Y; Ding, Z; Gong, Y; Jiang, H; Liu, X; Song, X; Wang, F; Wang, T; Wang, W; Zhang, N; Zhang, W; Zhang, Z	1
Gentry, CA; Williams, RJ	1
Bork, JT; D'Angelo, RG; Heil, EL; Johnson, JK	1
Hulin, A; Khoudour, N; Legrand, T; Tournier, N; Vodovar, D	1
Badal, RE; Biedenbach, DJ; Giao, PT; Hung Van, P; Phuong, DM; Su Minh Tuyet, N; Thi Thanh Nga, T; Vu Trung, N	1
Lavigne, JP; Meiller, E; Merens, A; Nicolas-Chanoine, MH; Pantel, A; Robert, J	1
Cantón, R; Chang, KT; Gao, S; Ledesma, KR; Oliver, A; Phe, K; Sánchez-Díaz, AM; Tam, VH; Van Bambeke, F; Zamorano, L; Zhou, J	1
Chang, HC; Chen, JC; Chen, PL; Ko, WC; Shih, CH; Su, IH; Sun, YN; Yeh, FH	1
Falagas, ME; Kofteridis, DP; Maraki, S; Mavromanolaki, VE; Perdikis, D; Samonis, G; Vardakas, KZ	1
Kim, HS; Kim, HY; Kim, YK; Lee, J; Lee, JA; Lee, SS; Seo, YB; Song, W; Uh, Y	1
Monogue, ML; Nicolau, DP	1
Kim, JH; Kim, MJ; Kim, SB; Sohn, JW; Suh, JW; Yang, KS; Yoon, YK	1
Rybak, MJ; Tran, N	1
An, G; Bach, T; D'Cunha, R; Li, P; Nalbant, D; Winokur, P; Young, BA; Zhang, J	1
Albanèse, J; Bornet, C; Curti, C; Fersing, C; Guinard, B; Lamy, E; Mathias, F; Primas, N; Souab, HK; Vanelle, P	1
Ammerman, NC; Kaushik, A; Nuermberger, EL; Parrish, NM	1
Cobian, J; Hall, B; Miller, J; Wilson, K	1
Guerci, P; Novy, E; Roger, C; Scala-Bertola, J	1
Delattre, IK; Dugernier, T; Hites, M; Jacobs, F; Laterre, PF; Spapen, H; Taccone, FS; Wallemacq, PE	1
Cobb, WJ	1
Benken, LA; Chamberlain, AR; Jones, RL; Kaplan, JM; Murphy, ME; Stoneman, EM; Tang Girdwood, SC; Tang, PH; Vinks, AA	1
Anderson, WE; Hammer, J; Heffner, AC; Jaffa, RK; Medaris, LA; Pillinger, KE	1
Ahmed, N; Chen, XJC; Decano, A; Dubrovskaya, Y; Jen, SP; Marsh, K; Merchan, C; Siegfried, J	1
Burgess, DS; Clark, JA; Landmesser, KB	1
Crawford, R; Hobbs, ALV; Hobbs, DA; Perkins, NB	1
Freret, C; Le Terrier, C; Nordmann, P; Poirel, L; Seigneur, M	1
Bakathavatchalam, YD; C, GPD; D, TK; Gopikrishnan, M; Manesh, A; Ramireddy, S; Varghese, RP; Veeraraghavan, B; Walia, K	1

Reviews

4 review(s) available for beta-lactams and cefepime

Article	Year
Beta-lactam antibiotics: newer formulations and newer agents. Infectious disease clinics of North America, 2004, Volume: 18, Issue:3 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Ertapenem; Humans; Lactams; United States	2004
Anti-pseudomonal beta-lactams for the initial, empirical, treatment of febrile neutropenia: comparison of beta-lactams. The Cochrane database of systematic reviews, 2010, Nov-10, Issue:11 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Fever; Humans; Imipenem; Meropenem; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Thienamycins	2010
Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams. Critical care (London, England), 2011, Volume: 15, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Cefpirome; Ceftazidime; Cephalosporins; Critical Illness; Humans; Imipenem; Infections; Meropenem; Piperacillin; Thienamycins	2011
Treatment options for extended-spectrum beta-lactamase (ESBL) and AmpC-producing bacteria. Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:7 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Gram-Negative Aerobic Bacteria; Gram-Negative Bacterial Infections; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination	2016

Trials

4 trial(s) available for beta-lactams and cefepime

Article	Year
Ertapenem versus cefepime for initial empirical treatment of pneumonia acquired in skilled-care facilities or in hospitals outside the intensive care unit. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2006, Volume: 25, Issue:10 Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Cross Infection; Double-Blind Method; Drug Administration Schedule; Enterobacteriaceae; Enterobacteriaceae Infections; Ertapenem; Female; Humans; Intensive Care Units; Male; Middle Aged; Pneumonia, Bacterial; Prospective Studies; Skilled Nursing Facilities	2006
Population pharmacokinetics of four β-lactams in critically ill septic patients comedicated with amikacin. Clinical biochemistry, 2012, Volume: 45, Issue:10-11 Topics: Adult; Aged; Aged, 80 and over; Algorithms; Amikacin; Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Critical Illness; Drug Monitoring; Female; Humans; Male; Meropenem; Metabolic Clearance Rate; Middle Aged; Models, Biological; Piperacillin; Sepsis; Thienamycins; Tissue Distribution; Treatment Outcome	2012
Prolonged infusion antibiotics for suspected gram-negative infections in the ICU: a before-after study. The Annals of pharmacotherapy, 2013, Volume: 47, Issue:2 Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Cohort Studies; Cross Infection; Drug Administration Schedule; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals, Teaching; Hospitals, Urban; Humans; Infusions, Intravenous; Intensive Care Units; Length of Stay; Male; Meropenem; Middle Aged; Missouri; Penicillanic Acid; Pilot Projects; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins	2013
Randomized controlled trial of piperacillin-tazobactam, cefepime and ertapenem for the treatment of urinary tract infection caused by extended-spectrum beta-lactamase-producing Escherichia coli. BMC infectious diseases, 2017, 06-07, Volume: 17, Issue:1 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Cross Infection; Ertapenem; Escherichia coli; Escherichia coli Infections; Female; Genotype; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Republic of Korea; Tazobactam; Urinary Tract Infections	2017

Other Studies

55 other study(ies) available for beta-lactams and cefepime

Article	Year
Development of beta-lactam-resistant Enterobacter cloacae in mice. The Journal of infectious diseases, 1987, Volume: 156, Issue:2 Topics: Animals; Anti-Bacterial Agents; Ascitic Fluid; beta-Lactams; Cefepime; Cephalosporins; Drug Resistance, Microbial; Enterobacter; Enterobacteriaceae; Female; Lactams; Male; Mice; Mice, Inbred ICR	1987
In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:3 Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cefaclor; Cefadroxil; Cefatrizine; Cefepime; Cefixime; Cefotaxime; Cefpirome; Cefpodoxime; Ceftazidime; Ceftibuten; Ceftizoxime; Ceftriaxone; Cefuroxime; Cephalosporins; Cephradine; Drug Resistance, Microbial; Drug Resistance, Multiple; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Piperacillin; Pneumococcal Infections; Serotyping; Species Specificity; Streptococcus pneumoniae	1998
Nosocomial outbreak due to a multiresistant strain of Pseudomonas aeruginosa P12: efficacy of cefepime-amikacin therapy and analysis of beta-lactam resistance. Journal of clinical microbiology, 2001, Volume: 39, Issue:6 Topics: Adult; Amikacin; Bacterial Outer Membrane Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Cross Infection; Disease Outbreaks; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections; Ribotyping	2001
[Multicenter evaluation of the antimicrobial activity in vitro for six broad-spectrum beta-lactams in China using the E-test method]. Zhonghua yi xue za zhi, 2000, Volume: 80, Issue:5 Topics: Anti-Bacterial Agents; Bacteria; beta-Lactams; Cefepime; Cefoperazone; Ceftazidime; Ceftriaxone; Cephalosporins; China; Imipenem; Microbial Sensitivity Tests; Piperacillin	2000
Geographic variations in activity of broad-spectrum beta-lactams against Pseudomonas aeruginosa: summary of the worldwide SENTRY Antimicrobial Surveillance Program (1997-2000). Diagnostic microbiology and infectious disease, 2002, Volume: 43, Issue:3 Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Fluoroquinolones; Global Health; Humans; Population Surveillance; Pseudomonas aeruginosa; Pseudomonas Infections	2002
Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics. Oral microbiology and immunology, 2002, Volume: 17, Issue:5 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacteroidaceae Infections; beta-Lactams; Cefepime; Cefmetazole; Cefoperazone; Cefpirome; Ceftazidime; Ceftizoxime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Fusobacterium; Fusobacterium Infections; Gram-Positive Bacterial Infections; Humans; Imipenem; Lactams; Microbial Sensitivity Tests; Mouth Diseases; Penicillin G; Penicillins; Peptostreptococcus; Porphyromonas gingivalis; Prevotella; Streptococcal Infections; Streptococcus; Sulbactam	2002
Exploring the effectiveness of tazobactam against ceftazidime resistant Escherichia coli: insights from the comparison between susceptibility testing and beta-lactamase inhibition. FEMS microbiology letters, 2004, May-01, Volume: 234, Issue:1 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Enzyme Inhibitors; Ertapenem; Escherichia coli; Escherichia coli Infections; Lactams; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam	2004
In vitro killing of parenteral beta-lactams against standard and high inocula of extended-spectrum beta-lactamase and non-ESBL producing Klebsiella pneumoniae. Diagnostic microbiology and infectious disease, 2004, Volume: 49, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Culture Media, Conditioned; Drug Resistance, Bacterial; Humans; In Vitro Techniques; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sensitivity and Specificity; Tazobactam; Thienamycins	2004
In vitro activities of beta-lactam antibiotics alone and in combination with sulbactam against Gram-negative bacteria. International journal of antimicrobial agents, 2004, Volume: 23, Issue:6 Topics: Acinetobacter baumannii; Ampicillin; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cefepime; Cefoperazone; Cefotaxime; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Bacterial; Enterobacter cloacae; Enzyme Inhibitors; Gram-Negative Bacteria; Humans; Imipenem; Klebsiella pneumoniae; Microbial Sensitivity Tests; Serratia marcescens; Sulbactam	2004
Cefepime and the inoculum effect in tests with Klebsiella pneumoniae producing plasmid-mediated AmpC-type beta-lactamase. The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Colony Count, Microbial; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Plasmids	2004
Relationship between pharmacokinetics and pharmacodynamics of beta-lactams and outcome. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2004, Volume: 10, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cefepime; Ceftriaxone; Cephalosporins; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Piperacillin; Treatment Outcome	2004
Continuous infusion beta-lactams for intensive care unit pulmonary infections. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2005, Volume: 11, Issue:5 Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Computer Simulation; Drug Combinations; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Intensive Care Units; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; United States	2005
Intermittent administration of betalactam-antibiotics for treatment of severe infection in hemodialysis patients. European journal of medical research, 2005, Apr-20, Volume: 10, Issue:4 Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactams; C-Reactive Protein; Cefepime; Ceftazidime; Cephalosporins; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Piperacillin; Renal Dialysis; Treatment Outcome	2005
Emergence of cefotaxime resistance in Citrobacter freundii causing necrotizing fasciitis and osteomyelitis. The Journal of infection, 2006, Volume: 53, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Cefotaxime; Cephalosporin Resistance; Cephalosporins; Citrobacter freundii; Enterobacteriaceae Infections; Ertapenem; Fasciitis, Necrotizing; Female; Humans; Middle Aged; Osteomyelitis; Wounds and Injuries	2006
Trough serum concentrations of beta-lactam antibiotics in cancer patients: inappropriateness of conventional schedules to pharmacokinetic/pharmacodynamic properties of beta-lactams. International journal of antimicrobial agents, 2006, Volume: 27, Issue:2 Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Drug Administration Schedule; Female; Humans; Imipenem; Male; Middle Aged; Neoplasms; Neutropenia; Prospective Studies	2006
Effect of porins and plasmid-mediated AmpC beta-lactamases on the efficacy of beta-lactams in rat pneumonia caused by Klebsiella pneumoniae. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6 Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Colony Count, Microbial; Imipenem; In Vitro Techniques; Klebsiella Infections; Klebsiella pneumoniae; Male; Meropenem; Microbial Sensitivity Tests; Plasmids; Pneumonia, Bacterial; Porins; Rats; Rats, Wistar; Thienamycins; Treatment Outcome	2006
Susceptibilities of Propionibacterium acnes ophthalmic isolates to ertapenem, meropenem, and cefepime. Journal of clinical microbiology, 2006, Volume: 44, Issue:11 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Ertapenem; Eye; Meropenem; Microbial Sensitivity Tests; Propionibacterium acnes; Rabbits; Thienamycins	2006
High-level cefepime resistance in Escherichia coli from Singapore producing OXA-1 beta-lactamase. International journal of antimicrobial agents, 2008, Volume: 31, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporin Resistance; Cephalosporins; Ertapenem; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; Singapore	2008
Simultaneous determination of five beta-lactam antibiotics (cefepim, ceftazidim, cefuroxim, meropenem and piperacillin) in human plasma by high-performance liquid chromatography with ultraviolet detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Mar-15, Volume: 864, Issue:1-2 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cefuroxime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Stability; Humans; Meropenem; Piperacillin; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Thienamycins	2008
Restoration of susceptibility of intracellular methicillin-resistant Staphylococcus aureus to beta-lactams: comparison of strains, cells, and antibiotics. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cefepime; Cefuroxime; Cell Line; Cells, Cultured; Cephalosporins; Cloxacillin; Humans; Hydrogen-Ion Concentration; Imipenem; Meropenem; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Oxacillin; Phagocytosis; Staphylococcus aureus; Thienamycins	2008
Comparison of different methods of determining beta-lactam susceptibility in clinical strains of Pseudomonas aeruginosa. Journal of medical microbiology, 2009, Volume: 58, Issue:Pt 5 Topics: Anti-Bacterial Agents; Automation; Aztreonam; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Genetic Predisposition to Disease; Humans; Imipenem; Microbial Sensitivity Tests; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections	2009
[Comparative activity of ertapenem against extended-spectrum beta-lactamase-producing or plasmid-mediated AmpC beta-lactamase-producing Klebsiella pneumoniae]. Enfermedades infecciosas y microbiologia clinica, 2010, Volume: 28, Issue:1 Topics: Amikacin; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Ertapenem; Imipenem; Klebsiella pneumoniae; Microbial Sensitivity Tests; Porins; R Factors; Substrate Specificity	2010
Outbreaks of imipenem resistant Acinetobacter baumannii producing OXA-23 beta-lactamase in a tertiary care hospital in Korea. Yonsei medical journal, 2009, Dec-31, Volume: 50, Issue:6 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Ciprofloxacin; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Gentamicins; Humans; Imipenem; Korea; Microbial Sensitivity Tests	2009
Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock. Critical care (London, England), 2010, Volume: 14, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Prospective Studies; Sepsis; Shock, Septic; Tazobactam; Thienamycins	2010
Molecular analysis of antimicrobial agent translocation through the membrane porin BpsOmp38 from an ultraresistant Burkholderia pseudomallei strain. Biochimica et biophysica acta, 2011, Volume: 1808, Issue:6 Topics: Amino Acid Sequence; Anti-Infective Agents; Bacterial Outer Membrane Proteins; beta-Lactams; Biological Transport; Burkholderia pseudomallei; Cefepime; Ceftazidime; Cephalosporins; Ertapenem; Humans; Imipenem; Kinetics; Lipid Bilayers; Melioidosis; Meropenem; Models, Molecular; Molecular Sequence Data; Norfloxacin; Penicillin G; Phospholipids; Porins; Protein Conformation; Sequence Homology, Amino Acid; Thienamycins	2011
AmpG inactivation restores susceptibility of pan-beta-lactam-resistant Pseudomonas aeruginosa clinical strains. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Aztreonam; Bacterial Proteins; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Membrane Transport Proteins; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Thienamycins	2011
Recommended β-lactam regimens are inadequate in septic patients treated with continuous renal replacement therapy. Critical care (London, England), 2011, Volume: 15, Issue:3 Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Dose-Response Relationship, Drug; Female; Humans; Intensive Care Units; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Practice Guidelines as Topic; Prospective Studies; Pseudomonas aeruginosa; Renal Replacement Therapy; Shock, Septic; Thienamycins	2011
Case-control study of drug monitoring of β-lactams in obese critically ill patients. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Case-Control Studies; Cefepime; Ceftazidime; Cephalosporins; Drug Monitoring; Enzyme Inhibitors; Female; Humans; Male; Meropenem; Middle Aged; Obesity; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Renal Replacement Therapy; Sepsis; Shock, Septic; Tazobactam; Thienamycins; Young Adult	2013
Comparative evaluation of six phenotypic methods for detecting extended-spectrum beta-lactamase-producing Enterobacteriaceae. Journal of infection in developing countries, 2014, Apr-15, Volume: 8, Issue:4 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Typing Techniques; beta-Lactamases; beta-Lactams; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Enterobacteriaceae; False Negative Reactions; False Positive Reactions; Female; Humans; India; Male; Microbial Sensitivity Tests; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Predictive Value of Tests	2014
Clinical comparison of ertapenem and cefepime for treatment of infections caused by AmpC beta-lactamase-producing Enterobacteriaceae. Scandinavian journal of infectious diseases, 2014, Volume: 46, Issue:11 Topics: Aged; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Case-Control Studies; Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Ertapenem; Female; Hospitalization; Humans; Male; Middle Aged; Retrospective Studies; Treatment Outcome	2014
Efficacy of cefepime, ertapenem and norfloxacin against leptospirosis and for the clearance of pathogens in a hamster model. Microbial pathogenesis, 2014, Volume: 77 Topics: Animal Structures; Animals; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Cricetinae; Disease Models, Animal; Ertapenem; Histocytochemistry; Leptospira interrogans serovar autumnalis; Leptospirosis; Norfloxacin; Survival Analysis; Treatment Outcome	2014
Trends in Susceptibility Rates and Extended-Spectrum β-Lactamase Production of Klebsiella pneumoniae in Bloodstream Infections Across the United States Veterans Affairs Healthcare System. Microbial drug resistance (Larchmont, N.Y.), 2015, Volume: 21, Issue:6 Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; beta-Lactams; Cefepime; Cefoxitin; Ceftazidime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Ertapenem; Fluoroquinolones; Gene Expression Regulation, Bacterial; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Sulbactam; United States; United States Department of Veterans Affairs	2015
Simultaneous Determination of Eight β-Lactam Antibiotics, Amoxicillin, Cefazolin, Cefepime, Cefotaxime, Ceftazidime, Cloxacillin, Oxacillin, and Piperacillin, in Human Plasma by Using Ultra-High-Performance Liquid Chromatography with Ultraviolet Detection Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8 Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactams; Cefazolin; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Chromatography, High Pressure Liquid; Cloxacillin; Drug Monitoring; Humans; Oxacillin; Piperacillin; Ultraviolet Rays	2016
Antimicrobial-resistant Pseudomonas aeruginosa and Acinetobacter baumannii From Patients With Hospital-acquired or Ventilator-associated Pneumonia in Vietnam. Clinical therapeutics, 2016, Volume: 38, Issue:9 Topics: Acinetobacter baumannii; Amikacin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Cross Infection; Doripenem; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gentamicins; Humans; Longitudinal Studies; Microbial Sensitivity Tests; Minocycline; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Tigecycline; Vietnam	2016
Development of an algorithm for phenotypic screening of carbapenemase-producing Enterobacteriaceae in the routine laboratory. BMC infectious diseases, 2017, 01-17, Volume: 17, Issue:1 Topics: Algorithms; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Clavulanic Acids; Drug Resistance, Bacterial; Enterobacteriaceae; Ertapenem; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Tazobactam; Thienamycins; Ticarcillin	2017
Determining β-lactam exposure threshold to suppress resistance development in Gram-negative bacteria. The Journal of antimicrobial chemotherapy, 2017, 05-01, Volume: 72, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Humans; Kinetics; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tandem Mass Spectrometry; Thienamycins	2017
Dielectrophoresis System for Testing Antimicrobial Susceptibility of Gram-Negative Bacteria to β-Lactam Antibiotics. Analytical chemistry, 2017, 04-18, Volume: 89, Issue:8 Topics: Anti-Infective Agents; beta-Lactams; Cefazolin; Cefepime; Ceftazidime; Doripenem; Electrodes; Electrophoresis; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Microscopy	2017
In vitro susceptibility and resistance phenotypes in contemporary Enterobacter isolates in a university hospital in Crete, Greece. Future microbiology, 2017, Volume: 12 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Child; Colistin; Drug Resistance, Multiple, Bacterial; Enterobacter; Enterobacteriaceae Infections; Greece; Hospitals, University; Humans; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tigecycline	2017
Translational Efficacy of Humanized Exposures of Cefepime, Ertapenem, and Levofloxacin against Extended-Spectrum-β-Lactamase-Producing Escherichia coli in a Murine Model of Complicated Urinary Tract Infection. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:11 Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Disease Models, Animal; Ertapenem; Escherichia coli Infections; Female; Humans; Levofloxacin; Mice, Inbred ICR; Microbial Sensitivity Tests; Urinary Tract Infections; Uropathogenic Escherichia coli	2017
The use of cefepime as a carbapenem-sparing antibiotic for treating uncomplicated acute pyelonephritis caused by extended-spectrum β-lactamase producing Escherichia coli. Infectious diseases (London, England), 2018, Volume: 50, Issue:3 Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Ertapenem; Escherichia coli; Escherichia coli Infections; Female; Hospitals, University; Humans; Male; Middle Aged; Pyelonephritis; Republic of Korea; Retrospective Studies; Risk Factors; Treatment Outcome	2018
β-Lactam Combinations with Vancomycin Show Synergistic Activity against Vancomycin-Susceptible Staphylococcus aureus, Vancomycin-Intermediate S. aureus (VISA), and Heterogeneous VISA. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:6 Topics: beta-Lactams; Cefazolin; Cefepime; Ceftaroline; Cephalosporins; Drug Synergism; Drug Therapy, Combination; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Nafcillin; Staphylococcal Infections; Vancomycin	2018
Quantification of Cefepime, Meropenem, Piperacillin, and Tazobactam in Human Plasma Using a Sensitive and Robust Liquid Chromatography-Tandem Mass Spectrometry Method, Part 1: Assay Development and Validation. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:9 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Chromatography, Liquid; Humans; Meropenem; Piperacillin; Sensitivity and Specificity; Tandem Mass Spectrometry; Tazobactam	2018
Stability Studies of Antipyocyanic Beta-Lactam Antibiotics Used in Continuous Infusion. Die Pharmazie, 2019, 06-01, Volume: 74, Issue:6 Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cefepime; Ceftazidime; Cilastatin; Cilastatin, Imipenem Drug Combination; Imipenem; Meropenem; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2019
New β-Lactamase Inhibitors Nacubactam and Zidebactam Improve the Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:9 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactams; Cefepime; Cyclooctanes; Microbial Sensitivity Tests; Mycobacterium abscessus; Piperidines	2019
Impact of SEP-1 on broad-spectrum combination antibiotic therapy in the emergency department. The American journal of emergency medicine, 2020, Volume: 38, Issue:12 Topics: Adult; Aged; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cefepime; Centers for Medicare and Medicaid Services, U.S.; Early Diagnosis; Early Medical Intervention; Emergency Service, Hospital; Female; Guideline Adherence; Hospital Mortality; Hospitalization; Humans; Male; Medical Overuse; Meropenem; Middle Aged; Patient Care Bundles; Piperacillin, Tazobactam Drug Combination; Reimbursement Mechanisms; Retrospective Studies; Sepsis; Shock, Septic; Soft Tissue Infections; Time-to-Treatment; United States; Urinary Tract Infections; Vancomycin	2020
Preliminary therapeutic drug monitoring data of β-lactams in critically ill patients with SARS-CoV-2 infection. Anaesthesia, critical care & pain medicine, 2020, Volume: 39, Issue:3 Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; beta-Lactams; Betacoronavirus; Cefepime; Coinfection; Confusion; Coronavirus Infections; COVID-19; Critical Illness; Cross Infection; Deep Sedation; Delirium; Drug Monitoring; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pandemics; Pneumonia, Ventilator-Associated; Pneumonia, Viral; Respiration, Artificial; SARS-CoV-2; Sepsis	2020
What is the optimal loading dose of broad-spectrum β-lactam antibiotics in septic patients? Results from pharmacokinetic simulation modelling. International journal of antimicrobial agents, 2020, Volume: 56, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Computer Simulation; Humans; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Piperacillin; Prospective Studies; Pseudomonas aeruginosa; Shock, Septic	2020
45-year-old man • fever • generalized rash • recent history of calcaneal osteomyelitis • Dx? The Journal of family practice, 2020, Volume: 69, Issue:7 Topics: beta-Lactams; Cefepime; Drug Hypersensitivity Syndrome; Exanthema; Fever; Humans; Male; Middle Aged; Osteomyelitis; Treatment Outcome	2020
Demonstrating Feasibility of an Opportunistic Sampling Approach for Pharmacokinetic Studies of β-Lactam Antibiotics in Critically Ill Children. Journal of clinical pharmacology, 2021, Volume: 61, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; beta-Lactams; Cefepime; Child; Child, Preschool; Comorbidity; Critical Illness; Feasibility Studies; Female; Humans; Intensive Care Units, Pediatric; Male; Meropenem; Piperacillin; Prospective Studies	2021
Empiric aztreonam is associated with increased mortality compared to beta-lactams in septic shock. The American journal of emergency medicine, 2021, Volume: 48 Topics: Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; APACHE; Aztreonam; beta-Lactams; Cefepime; Cohort Studies; Drug Hypersensitivity; Female; Fluoroquinolones; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Male; Meropenem; Middle Aged; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Risk Factors; Shock, Septic	2021
Safety of intravenous push administration of beta-lactams within a healthcare system. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2020, 04-27, Volume: 77, Issue:9 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Delivery of Health Care; Humans; Infusions, Intravenous; Retrospective Studies	2020
Time Above All Else: Pharmacodynamic Analysis of β-Lactams in Critically Ill Patients. Journal of clinical pharmacology, 2022, Volume: 62, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Critical Illness; Humans; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Piperacillin; Pseudomonas aeruginosa; Tazobactam	2022
Time to defervescence evaluation for extended- vs. standard-infusion cefepime in patients with acute leukemia and febrile neutropenia. Pharmacotherapy, 2022, Volume: 42, Issue:10 Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Febrile Neutropenia; Humans; Leukemia, Myeloid, Acute; Retrospective Studies	2022
Impact of Acquired Broad Spectrum β-Lactamases on Susceptibility to Novel Combinations Made of β-Lactams (Aztreonam, Cefepime, Meropenem, and Imipenem) and Novel β-Lactamase Inhibitors in Escherichia coli and Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2023, 07-18, Volume: 67, Issue:7 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Escherichia coli; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa	2023
Determination of potential combination of non-β-lactam, β-lactam, and β-lactamase inhibitors/β-lactam enhancer against class D oxacillinases producing Acinetobacter baumannii: Evidence from in-vitro, molecular docking and dynamics simulation. Journal of cellular biochemistry, 2023, Volume: 124, Issue:7 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Cefiderocol; Lactams; Molecular Docking Simulation	2023