Compounds > beta-lactams
Page last updated: 2024-09-04

beta-lactams and aspartic acid

beta-lactams has been researched along with aspartic acid in 4 studies

Compound Research Comparison

Studies
(beta-lactams)		Trials
(beta-lactams)		Recent Studies (post-2010)
(beta-lactams)		Studies
(aspartic acid)		Trials
(aspartic acid)		Recent Studies (post-2010) (aspartic acid)
7,5791793,39523,0054174,018

Protein Interaction Comparison

ProteinTaxonomybeta-lactams (IC50)aspartic acid (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.638
Excitatory amino acid transporter 1Homo sapiens (human)90.1265
Excitatory amino acid transporter 2Homo sapiens (human)11
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)1.638
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)1.638
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)1.638
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)1.638
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)1.638
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)1.638

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giakkoupi, P; Legakis, NJ; Tzelepi, E; Tzouvelekis, LS1
Chen, CC; Herzberg, O1
Eriguchi, Y; Haruta, S; Nukaga, M; O'Hara, K; Sawai, T; Yamaguchi, H; Yamamoto, ET1
Amin, M; Rawls, SM; Robinson, W; Tallarida, R1

Other Studies

4 other study(ies) available for beta-lactams and aspartic acid

ArticleYear
Aspartic acid for asparagine substitution at position 276 reduces susceptibility to mechanism-based inhibitors in SHV-1 and SHV-5 beta-lactamases.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:1

    Topics: Amino Acid Substitution; Anti-Bacterial Agents; Asparagine; Aspartic Acid; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Enzyme Inhibitors; Escherichia coli; Inhibitory Concentration 50; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam

1999
Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp.
    Protein engineering, 1999, Volume: 12, Issue:7

    Topics: Acylation; Anti-Bacterial Agents; Asparagine; Aspartic Acid; beta-Lactamases; beta-Lactams; Catalytic Domain; Crystallography, X-Ray; Glutamic Acid; Glutamine; Kinetics; Models, Molecular; Mutation; Protein Conformation; Staphylococcus aureus; Structure-Activity Relationship

1999
Functional analysis of the active site of a metallo-beta-lactamase proliferating in Japan.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:9

    Topics: Anti-Bacterial Agents; Apoenzymes; Aspartic Acid; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Binding Sites; Binding, Competitive; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Histidine; Humans; Japan; Kinetics; Klebsiella pneumoniae; Ligands; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Zinc

2000
The beta-lactam antibiotic, ceftriaxone, attenuates morphine-evoked hyperthermia in rats.
    British journal of pharmacology, 2007, Volume: 151, Issue:7

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anti-Bacterial Agents; Aspartic Acid; beta-Lactams; Body Temperature; Ceftriaxone; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Rats; Rats, Sprague-Dawley; Riluzole; Time Factors

2007