beta-hydroxyisovalerylshikonin has been researched along with shikonin in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| An, S; Jeong, TS; Lee, WS; Paik, YK; Park, YD | 1 |
| Cui, XR; Gao, L; Komada, F; Koyanagi, J; Saito, S; Shimamura, T; Suzuki, N; Tsukada, M | 1 |
| Cho, JK; Jeong, HJ; Kim, JY; Kim, YM; Lee, WS; Park, JY; Park, KH; Park, SJ; Ryu, YB | 1 |
| Aiuchi, T; Cao, J; Hashimoto, S; Ida, Y; Masuda, Y; Miyakoshi, M; Nakajo, S; Nakaya, K; Xu, M | 1 |
| Aiuchi, T; Hashimoto, S; Masuda, Y; Nakajo, S; Nakaya, K; Shibuya, M; Uehara, Y; Xu, Y; Yamori, T | 1 |
| Itabe, H; Kajimoto, S; Kojima, S; Komi, Y; Masuda, M; Nakajo, S; Nakaya, K; Oettgen, P; Shibuya, M; Shimamura, M; Shimokado, K; Suzuki, Y | 1 |
| Chung, SI; Ha, JH; Jang, J; Yoon, Y | 1 |
| Asahina, Y; Hashiba, T; Hayashi, T; Honda, M; Kaneko, S; Nio, K; Nishitani, M; Okada, H; Suda, T; Sugimoto, S; Takatori, H; Yamashita, T | 1 |
8 other study(ies) available for beta-hydroxyisovalerylshikonin and shikonin
| Article | Year |
|---|---|
Human ACAT inhibitory effects of shikonin derivatives from Lithospermum erythrorhizon.
Topics: Chloroform; Enzyme Inhibitors; Humans; Isoenzymes; Lithospermum; Microscopy, Fluorescence; Naphthoquinones; Plant Roots; Solvents; Sterol O-Acyltransferase; Structure-Activity Relationship; Substrate Specificity | 2007 |
Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones.
Topics: Anthraquinones; Antineoplastic Agents, Phytogenic; Boraginaceae; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Lithospermum; Magnetic Resonance Spectroscopy; Naphthoquinones; Rheum; Spectrometry, Mass, Electrospray Ionization | 2008 |
Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases.
Topics: Glycoside Hydrolases; Hydrolases; Kinetics; Lithospermum; Naphthoquinones; Neuraminidase | 2012 |
beta-hydroxyisovalerylshikonin inhibits the cell growth of various cancer cell lines and induces apoptosis in leukemia HL-60 cells through a mechanism different from those of Fas and etoposide.
Topics: Antineoplastic Agents; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspases; Cell Division; DNA Fragmentation; Drug Screening Assays, Antitumor; Enzyme Activation; Etoposide; fas Receptor; HL-60 Cells; Humans; Naphthoquinones; Nucleic Acid Synthesis Inhibitors; Signal Transduction; Tumor Cells, Cultured | 1999 |
Beta-hydroxyisovalerylshikonin is a novel and potent inhibitor of protein tyrosine kinases.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Antineoplastic Agents, Phytogenic; Cell Death; Dose-Response Relationship, Drug; Enzyme Inhibitors; ErbB Receptors; Humans; Inhibitory Concentration 50; Kinetics; Mice; Models, Chemical; Naphthoquinones; Protein-Tyrosine Kinases; Tumor Cells, Cultured | 2002 |
Mechanism of inhibition of tumor angiogenesis by beta-hydroxyisovalerylshikonin.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Blotting, Western; Carcinoma, Lewis Lung; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Chickens; Chorioallantoic Membrane; Drugs, Chinese Herbal; Electrophoretic Mobility Shift Assay; Female; Immunoenzyme Techniques; Immunoprecipitation; Luciferases; Mice; Mice, Inbred C57BL; Naphthoquinones; Neovascularization, Pathologic; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2009 |
AMPK and SREBP-1c mediate the anti-adipogenic effect of β-hydroxyisovalerylshikonin.
Topics: 3T3-L1 Cells; Acetyl-CoA Carboxylase; Aldehyde Oxidoreductases; AMP-Activated Protein Kinases; Animals; Cell Survival; Mice; Naphthoquinones; Reverse Transcriptase Polymerase Chain Reaction; Stearoyl-CoA Desaturase; Sterol Regulatory Element Binding Protein 1 | 2016 |
Beta-Hydroxyisovaleryl-Shikonin Eradicates Epithelial Cell Adhesion Molecule-Positive Liver Cancer Stem Cells by Suppressing dUTP Pyrophosphatase Expression.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Epithelial Cell Adhesion Molecule; Fluorouracil; Humans; Liver Neoplasms; Neoplastic Stem Cells | 2023 |