beta-funaltrexamine and incarvillateine

beta-funaltrexamine has been researched along with incarvillateine* in 1 studies

Other Studies

1 other study(ies) available for beta-funaltrexamine and incarvillateine

ArticleYear
Pharmacological study on the novel antinociceptive agent, a novel monoterpene alkaloid from Incarvillea sinensis.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:10

    To determine the antinociceptive mechanism of incarvillateine (INCA), the opiate antagonists nor-binaltorphimine (nor-BNI), beta-funaltrexamine (beta-FNA) and naltrindole (NTI) were pretreated prior to its injection in a formalin test. The antinociceptive effect of INCA was antagonized by nor-BNI (kappa-receptor antagonist) and beta-FNA (mu-receptor antagonist), while NTI (delta-receptor antagonist) did not influence its effect. Furthermore, the antinociceptive effect of INCA was blocked by theophylline (THEO), an adenosine-receptor antagonist. These results suggested that the antinociceptive effect arose from the activation of mu-, kappa-receptors and adenosine-receptor.

    Topics: Alkaloids; Analgesics; Bignoniaceae; Monoterpenes; Naltrexone; Narcotic Antagonists; Purinergic P1 Receptor Antagonists

2005