Compounds > beta-ethyl, beta-methyl-thiobutyrolactone
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beta-ethyl, beta-methyl-thiobutyrolactone and 2-ethyl-2-methyl-4-butyrolactone

beta-ethyl, beta-methyl-thiobutyrolactone has been researched along with 2-ethyl-2-methyl-4-butyrolactone in 3 studies

Compound Research Comparison

Studies
(beta-ethyl, beta-methyl-thiobutyrolactone)		Trials
(beta-ethyl, beta-methyl-thiobutyrolactone)		Recent Studies (post-2010)
(beta-ethyl, beta-methyl-thiobutyrolactone)		Studies
(2-ethyl-2-methyl-4-butyrolactone)		Trials
(2-ethyl-2-methyl-4-butyrolactone)		Recent Studies (post-2010) (2-ethyl-2-methyl-4-butyrolactone)
600900

Protein Interaction Comparison

ProteinTaxonomybeta-ethyl, beta-methyl-thiobutyrolactone (IC50)2-ethyl-2-methyl-4-butyrolactone (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)2.28
GABA theta subunitRattus norvegicus (Norway rat)2.28
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)2.28

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Canney, DJ; Covey, DF; Ferrendelli, JA; Holland, KD; Levine, JA; McKeon, AC1
Covey, DF; Ferrendelli, JA; Levine, JA1
Covey, DF; Ferrendelli, JA; Gross, RA1

Other Studies

3 other study(ies) available for beta-ethyl, beta-methyl-thiobutyrolactone and 2-ethyl-2-methyl-4-butyrolactone

ArticleYear
Synthesis and structure-activity studies of alkyl-substituted gamma-butyrolactones and gamma-thiobutyrolactones: ligands for the picrotoxin receptor.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:4

    Topics: 4-Butyrolactone; Alkylation; Animals; Anticonvulsants; Brain; Convulsants; Female; Ligands; Mice; Mice, Inbred Strains; Molecular Structure; Neurotoxins; Picrotoxin; Receptors, GABA-A; Seizures; Structure-Activity Relationship

1991
Alkyl-substituted thiolo-, thiono-, and dithio-gamma-butyrolactones: new classes of convulsant and anticonvulsant agents.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:10

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Convulsants; Female; Furans; Mice; Structure-Activity Relationship

1986
Voltage-dependent calcium channels as targets for convulsant and anticonvulsant alkyl-substituted thiobutyrolactones.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: 4-Butyrolactone; Animals; Animals, Newborn; Anticonvulsants; Calcium Channels; Cells, Cultured; Convulsants; Ethosuximide; Evoked Potentials; Ganglia, Spinal; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley

1997