beta-carotene has been researched along with hesperetin* in 1 studies
1 other study(ies) available for beta-carotene and hesperetin
| Article | Year |
|---|---|
Hesperetin and Hesperidin Improved β-Carotene Incorporation Efficiency, Intestinal Cell Uptake, and Retinoid Concentrations in Tissues.
Dietary constituents can influence the bioavailability of carotenoids. This study investigated the effect of citrus flavanones on β-carotene (Bc) bioavailability using four experimental models: in vitro digestion procedure, synthetic mixed micelles, Caco-2 cell monolayers, and gavage experiments in mice. The addition of hesperetin (Hes, 25 μM) and hesperidin (Hes-G, 25 μM) standards significantly increased the incorporation efficiency of the Bc standard to 68.7 ± 3.6 and 75.2 ± 7.5% ( p < 0.05), respectively. However, the addition of naringenin (Nar, 25 μM) and naringin (Nar-G, 25 μM) standards significantly reduced the incorporation efficiency of Bc by 23.8 and 26.4%, respectively ( p < 0.05). The increases in scavenger receptor class B type I (SR-BI) expression promoted by citrus flavanones played an important role in Bc cellular absorption in the Caco-2 cell model. Furthermore, after 3 days of gavage, four citrus flavanones (7.5 mg kg Topics: Animals; beta Carotene; Biological Availability; Biological Transport; Caco-2 Cells; Citrus; Hesperidin; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Retinoids | 2019 |