beta-carboline-3-carboxylic acid ethyl ester has been researched along with tert-butyl beta-carboline-3-carboxylate in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allen, MS; Cook, JM; Costantino, G; Dorn, LJ; Hagen, TJ; Koehler, KF; LaLoggia, AJ; Martin, MJ; Skolnick, P | 1 |
| Allen, MS; Codding, PW; Hagen, TJ; Koehler, KF; Martin, MJ; Narayanan, K; Schindler, LR; Schultz, C; Tan, YC; Trudell, ML | 1 |
| Good, AC; Peterson, SJ; Richards, WG | 1 |
| Platt, DE; Silverman, BD | 1 |
| Karplus, M; So, SS | 1 |
| Cook, JM; Cox, ED; Diaz-Arauzo, H; Harris, B; Huang, Q; Ma, C; McKernan, R; Reddy, MS; Skolnick, P | 1 |
| Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S | 1 |
| Ahmad, K; Beg, Y; Cho, SJ; Muddassar, M; Pasha, FA | 1 |
| Clayton, T; Cook, J; DeLorey, TM; Furtmüller, R; Halliwell, RF; Harris, D; Huck, S; Sahbaie, P; Sieghart, W | 1 |
| Clayton, T; Cook, JM; Cromer, BA; Ma, C; Majumder, S; Namjoshi, OA; Petrou, S; Platt, DM; Roth, BL; VanLinn, ML; Yin, W | 1 |
| Cook, JM; Hagen, T; Katz, JL; Suzuki, T; Takada, K | 1 |
| Cook, JA; Guzman, F; Hagen, TJ; Shannon, HE | 1 |
12 other study(ies) available for beta-carboline-3-carboxylic acid ethyl ester and tert-butyl beta-carboline-3-carboxylate
| Article | Year |
|---|---|
Predictive binding of beta-carboline inverse agonists and antagonists via the CoMFA/GOLPE approach.
Topics: Animals; Binding, Competitive; Carbolines; Cerebral Cortex; Convulsants; GABA-A Receptor Antagonists; In Vitro Techniques; Male; Mice; Models, Molecular; Models, Statistical; Molecular Conformation; Rats; Receptors, GABA-A; Regression Analysis; Structure-Activity Relationship | 1992 |
Synthetic and computer-assisted analyses of the pharmacophore for the benzodiazepine receptor inverse agonist site.
Topics: Binding Sites; Carbolines; Chemical Phenomena; Chemistry; Computer Simulation; Ligands; Models, Chemical; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship | 1990 |
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.
Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship | 1993 |
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.
Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone | 1996 |
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.
Topics: Cholinesterase Inhibitors; Dopamine beta-Hydroxylase; Drug Design; Enzyme Inhibitors; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Conformation; Molecular Structure; Neural Networks, Computer; Phosphorylases; Receptors, Aryl Hydrocarbon; Static Electricity; Structure-Activity Relationship | 1997 |
Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423)
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Binding, Competitive; Carbolines; Cell Line; Cerebral Cortex; Drug Design; GABA Agonists; Humans; Male; Mice; Muscle Relaxation; Rats; Receptors, GABA-A; Recombinant Proteins; Seizures; Structure-Activity Relationship | 1998 |
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship | 2000 |
3D and quantum QSAR of non-benzodiazepine compounds.
Topics: Benzodiazepines; Carbolines; Imaging, Three-Dimensional; Imidazoles; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Pyrimidines; Quantitative Structure-Activity Relationship; Software | 2008 |
Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit.
Topics: Animals; Behavior, Animal; Benzodiazepines; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Databases, Factual; Electrophysiology; Female; Ligands; Male; Memory; Mice; Models, Molecular; Molecular Structure; Oocytes; Protein Isoforms; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis | 2008 |
Design, synthesis, and subtype selectivity of 3,6-disubstituted β-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse.
Topics: Alcoholism; Animals; Benzodiazepines; Binding Sites; Carbolines; Cell Line; Computer Simulation; GABA-A Receptor Antagonists; Humans; Protein Subunits; Rats; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship | 2010 |
Behavioral effects of benzodiazepine antagonists in chlordiazepoxide tolerant and non-tolerant rats.
Topics: Animals; Behavior, Animal; Benzodiazepines; Carbolines; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Tolerance; Flumazenil; Male; Pyrazoles; Rats; Rats, Inbred F344 | 1989 |
Beta-carbolines as antagonists of the discriminative stimulus effects of diazepam in rats.
Topics: Animals; Carbolines; Diazepam; Discrimination Learning; Harmine; Male; Picrotoxin; Rats; Rats, Inbred F344 | 1988 |