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beta-carboline-3-carboxylic acid ethyl ester and gamma-aminobutyric acid

beta-carboline-3-carboxylic acid ethyl ester has been researched along with gamma-aminobutyric acid in 38 studies

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199034 (89.47)18.7374
1990's3 (7.89)18.2507
2000's0 (0.00)29.6817
2010's1 (2.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Blakeman, DP; Im, WB1
Alho, H; Costa, E; Ferrero, P; Guidotti, A; Santi, MR; Vicini, S1
Akaike, N; Fukuda, T; Oyama, Y; Yakushiji, T1
Arbilla, S; Langer, SZ; Lista, A1
Gobbi, M; Mennini, T; Perin, L; Salmona, M1
Clow, A; Glover, V; Sandler, M1
Moura, D; Soares-da-Silva, P1
Cole, R; De Vellis, J; Noble, EP; Syapin, PJ1
Cohen, RM; Havoundjian, H; Paul, SM; Skolnick, P1
Hammond, JR; Martin, IL1
Chang, LR; Lee, HK; Tao, PL1
Ciuffi, M; Franchi-Micheli, S; Luzzi, S; Rosi, E; Spagnesi, S; Zilletti, L1
Morrow, AL; Paul, SM1
Macdonald, RL; Skerritt, JH1
Little, HJ1
Moncada, VY; Paul, SM; Schweri, MM; Skolnick, P; Williams, EF1
Paul, SM; Skolnick, P1
Cardinali, DP; Lowenstein, PR1
Haefely, W2
Polc, P; Ropert, N; Wright, DM1
Goodwin, FK; Marangos, PJ; Patel, J1
Marangos, PJ; Patel, J1
Cowen, PJ; Little, HJ; Nutt, DJ1
Hirsch, JD; Kochman, RL1
Horton, RW; Prestwich, SA; Stapleton, SR1
Braestrup, C; Honoré, T; Jensen, LH; Nielsen, M; Petersen, EN1
Corda, MG; Costa, E; Guidotti, A1
Brown, CL; Martin, IL1
Biggio, G; Concas, A; Crisponi, G; Nurchi, V; Salis, M; Serra, M1
Saneyoshi, M; Sung, SC1
Biggio, G; Concas, A; Corda, MG; Crisponi, C; Gessa, GL; Nurchi, V; Salis, M; Serra, M1
Barrett, JE; Martin, JV; Mendelson, WB; Paul, SM; Schweri, MM; Skolnick, P1
Biggio, G; Concas, A; Corda, MG; Salis, M; Serra, M1
Braestrup, C; Johnston, GA; Skerritt, JH1
DaSilva, AM; Gatti, PJ; Gillis, RA; Homby, PJ; Mandal, AK; Norman, WP1
Hu, HZ; Li, ZW; Shao, M1

Reviews

5 review(s) available for beta-carboline-3-carboxylic acid ethyl ester and gamma-aminobutyric acid

ArticleYear
[Drug activation of GABAergic transmission in the central nervous system: benzodiazepines and GABAergic agonists].
    Acta medica portuguesa, 1985, Volume: 6, Issue:2

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Chemical Phenomena; Chemistry; Cyclic GMP; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Humans; Receptors, GABA-A; Synaptic Transmission; Valproic Acid

1985
The mechanism(s) of action of the benzodiazepines.
    Medicinal research reviews, 1981,Spring, Volume: 1, Issue:1

    Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Caffeine; Carbolines; Cats; Cattle; Diazepam; gamma-Aminobutyric Acid; Humans; Molecular Weight; Muscle Relaxation; Neurotransmitter Agents; Niacinamide; Purines; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures; Sleep Wake Disorders

1981
Antagonists of benzodiazepines.
    L'Encephale, 1983, Volume: 9, Issue:4 Suppl 2

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Binding, Competitive; Carbolines; Flumazenil; gamma-Aminobutyric Acid; Humans; Models, Chemical; Molecular Conformation; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptic Transmission

1983
Benzodiazepine receptor ligands with positive and negative efficacy.
    Neuropharmacology, 1983, Volume: 22, Issue:12B

    Topics: Acoustic Stimulation; Animals; Carbolines; Chlorides; gamma-Aminobutyric Acid; Humans; Ligands; Receptors, Cell Surface; Receptors, GABA-A; Seizures

1983
On a brain polypeptide functioning as a putative effector for the recognition sites of benzodiazepine and beta-carboline derivatives.
    Neuropharmacology, 1983, Volume: 22, Issue:12B

    Topics: Animals; Benzodiazepinones; Brain Chemistry; Carbolines; Carrier Proteins; Chlorides; Flumazenil; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Ionophores; Ligands; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Organic Anion Transporters; Peptides; Receptors, Cell Surface; Receptors, GABA-A

1983

Other Studies

33 other study(ies) available for beta-carboline-3-carboxylic acid ethyl ester and gamma-aminobutyric acid

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Correlation between gamma-aminobutyric acidA receptor ligand-induced changes in t-butylbicyclophosphoro[35S]thionate binding and 36Cl- uptake in rat cerebrocortical membranes.
    Molecular pharmacology, 1991, Volume: 39, Issue:3

    Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Chloride Channels; Chlorides; Desoxycorticosterone; Diazepam; Ethanol; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Membrane Proteins; Pentobarbital; Pregnanolone; Rats; Receptors, GABA-A; Synaptosomes

1991
Gamma-aminobutyric acid and chloride channels: regulation by neuropeptides.
    Regulatory peptides. Supplement, 1985, Volume: 4

    Topics: Animals; Carbolines; Cells, Cultured; Cerebellum; Chlorides; gamma-Aminobutyric Acid; Hippocampus; Humans; Ion Channels; Muscimol; Nerve Tissue Proteins; Receptors, GABA-A

1985
Effects of benzodiazepines and non-benzodiazepine compounds on the GABA-induced response in frog isolated sensory neurones.
    British journal of pharmacology, 1989, Volume: 98, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Carbolines; Drug Synergism; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons, Afferent; Rana catesbeiana

1989
Modulation of the electrically evoked release of 5-[3H]hydroxytryptamine from rat cerebral cortex: effects of alpidem, CL 218872, and diazepam.
    Journal of neurochemistry, 1988, Volume: 51, Issue:5

    Topics: Animals; Benzodiazepines; Carbolines; Cerebral Cortex; Diazepam; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Imidazoles; Male; Monoamine Oxidase Inhibitors; Pargyline; Pyrazoles; Pyridazines; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin

1988
Rapid internalization of benzodiazepine receptors in the rat cortex induced by handling.
    Advances in biochemical psychopharmacology, 1988, Volume: 45

    Topics: Animals; Bicuculline; Carbolines; Cerebral Cortex; Corticosterone; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Ligands; Male; Rats; Receptors, GABA-A; Stress, Physiological; Synaptic Membranes; Viscosity

1988
Triazolam, an anomalous benzodiazepine receptor ligand: in vitro characterization of alprazolam and triazolam binding.
    Journal of neurochemistry, 1985, Volume: 45, Issue:2

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Carbolines; Clonazepam; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Triazolam

1985
Benzodiazepine binding characteristics of embryonic rat brain neurons grown in culture.
    Journal of neurochemistry, 1985, Volume: 45, Issue:6

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Cells, Cultured; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Neurons; Pyridazines; Rats; Receptors, GABA-A

1985
Differential sensitivity of "central" and "peripheral" type benzodiazepine receptors to phospholipase A2.
    Journal of neurochemistry, 1986, Volume: 46, Issue:3

    Topics: Animals; Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kidney; Male; Myocardium; Pentobarbital; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A

1986
Solubilization of the benzodiazepine/gamma-aminobutyric acid receptor complex: comparison of the detergents octylglucopyranoside and 3-[(3-cholamidopropyl)-dimethylammonio]1-propanesulfonate (CHAPS).
    Journal of neurochemistry, 1986, Volume: 47, Issue:4

    Topics: Animals; Carbolines; Cerebellum; Chlorides; Cholic Acids; Drug Stability; Flunitrazepam; gamma-Aminobutyric Acid; Glucosides; Glycosides; Male; Phospholipids; Pyrazoles; Rats; Receptors, GABA-A; Solubility; Synaptic Membranes

1986
Heterogeneity of [3H]ethyl beta-carboline-3-carboxylate binding sites and [3H]gamma-aminobutyric acid binding sites.
    The Chinese journal of physiology, 1986, Volume: 29, Issue:1

    Topics: Animals; Binding, Competitive; Carbolines; Cattle; Cerebral Cortex; Detergents; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Molecular Weight; Muscimol; Photolysis; Radioligand Assay; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptosomes

1986
Diazepam potentiates GABA-contraction in guinea-pig ileum.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 279, Issue:1

    Topics: Animals; Baclofen; Benzodiazepinones; Carbolines; Diazepam; Drug Synergism; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth

1986
Benzodiazepine enhancement of gamma-aminobutyric acid-mediated chloride ion flux in rat brain synaptoneurosomes.
    Journal of neurochemistry, 1988, Volume: 50, Issue:1

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Chlorides; Clonazepam; Diazepam; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Synaptosomes

1988
Benzodiazepine receptor ligand actions on GABA responses. Beta-carbolines, purines.
    European journal of pharmacology, 1984, May-18, Volume: 101, Issue:1-2

    Topics: Animals; Carbolines; Cells, Cultured; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Indoles; Ligands; Mice; Neurons; Purines; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord

1984
The effects of benzodiazepine agonists, inverse agonists and Ro 15-1788 on the responses of the superior cervical ganglion to GABA in vitro.
    British journal of pharmacology, 1984, Volume: 83, Issue:1

    Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Carbolines; Chlordiazepoxide; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Sympathetic; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A

1984
An in vitro binding assay which differentiates benzodiazepine 'agonists' and 'antagonists'.
    European journal of pharmacology, 1982, Feb-19, Volume: 78, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Binding, Competitive; Carbolines; Flumazenil; gamma-Aminobutyric Acid; Indoles; Male; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A

1982
Characterization of flunitrazepam and beta-carboline high affinity binding in bovine pineal gland.
    Neuroendocrinology, 1983, Volume: 37, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding Sites; Carbolines; Cattle; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Kinetics; Pentobarbital; Pineal Gland; Rats; Species Specificity

1983
Antagonists of benzodiazepines: functional aspects.
    Advances in biochemical psychopharmacology, 1983, Volume: 38

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Carbolines; Chlorides; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channels; Narcotic Antagonists; Parasympathomimetics; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A; Substance-Related Disorders; Xanthines

1983
Ethyl beta-carboline-3-carboxylate antagonizes the action of GABA and benzodiazepines in the hippocampus.
    Brain research, 1981, Jul-27, Volume: 217, Issue:1

    Topics: Animals; Benzodiazepines; Carbolines; Diazepam; Electric Stimulation; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Indoles; Male; Midazolam; Neural Inhibition; Neurons; Rats; Receptors, Drug; Receptors, GABA-A

1981
[3H] Ethyl beta-carboline-3-carboxylate binding to the benzodiazepine receptor is not affected by GABA.
    European journal of pharmacology, 1981, Jul-10, Volume: 72, Issue:4

    Topics: Animals; Brain; Carbolines; Cell Membrane; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Rats; Receptors, Drug; Receptors, GABA-A

1981
Properties of [3H] beta-carboline-3-carboxylate ethyl ester binding to the benzodiazepine receptor.
    Life sciences, 1981, Oct-19, Volume: 29, Issue:16

    Topics: Animals; Benzodiazepines; Brain; Carbolines; Diazepam; gamma-Aminobutyric Acid; Indoles; Kidney; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A

1981
Unusual interactions of benzodiazepine receptor antagonists.
    Nature, 1982, Feb-04, Volume: 295, Issue:5848

    Topics: Animals; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Biological Assay; Carbolines; Flumazenil; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Indoles; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures

1982
Thermodynamic changes associated with benzodiazepine and alkyl beta-carboline-3-carboxylate binding to rat brain homogenates.
    Molecular pharmacology, 1982, Volume: 22, Issue:2

    Topics: Animals; Benzodiazepines; Brain; Carbolines; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Male; Nickel; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Temperature; Thermodynamics

1982
Regional heterogeneity of benzodiazepine binding sites in rat brain.
    European journal of pharmacology, 1982, Oct-22, Volume: 84, Issue:3-4

    Topics: Animals; Binding, Competitive; Brain; Carbolines; Cerebellum; Chlorides; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Rats; Receptors, Cell Surface; Receptors, GABA-A

1982
Interactions of different ligand classes with the benzodiazepine receptor.
    Advances in biochemical psychopharmacology, 1983, Volume: 38

    Topics: Affinity Labels; Animals; Benzodiazepinones; Binding, Competitive; Carbolines; Flumazenil; gamma-Aminobutyric Acid; Humans; Ligands; Membranes; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sodium Chloride

1983
Evidence for an involvement of GABA receptors in the mediation of the proconvulsant action of ethyl-beta-carboline-3-carboxylate.
    Neuropharmacology, 1984, Volume: 23, Issue:3

    Topics: Animals; Binding Sites; Carbolines; Cerebral Cortex; Drug Synergism; gamma-Aminobutyric Acid; Hippocampus; Indoles; Injections, Intraventricular; Isoniazid; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures

1984
Effects of various 2-amino-6-alkyldithiopurines on brain specific [3H]diazepam binding.
    Biochemical pharmacology, 1984, Jun-01, Volume: 33, Issue:11

    Topics: Animals; Brain; Carbolines; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mercaptopurine; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1984
Stress and beta-carbolines decrease the density of low affinity GABA binding sites; an effect reversed by diazepam.
    Brain research, 1984, Jul-02, Volume: 305, Issue:1

    Topics: Animals; Binding Sites; Carbolines; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; Handling, Psychological; Indoles; Male; Rats; Rats, Inbred Strains; Stress, Physiological

1984
Pharmacokinetic and pharmacodynamic factors contributing to the convulsant action of beta-carboline-3-carboxylic acid esters.
    Life sciences, 1983, Oct-10, Volume: 33, Issue:15

    Topics: Animals; Brain; Carbolines; Convulsants; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Indoles; Kinetics; Male; Rats; Rats, Inbred Strains; Saimiri

1983
Ethyl-beta-carboline-3-carboxylate decreases [3H]GABA binding in membrane preparations of rat cerebral cortex.
    European journal of pharmacology, 1983, Apr-22, Volume: 89, Issue:1-2

    Topics: Animals; Brain; Carbolines; gamma-Aminobutyric Acid; Indoles; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains

1983
Modulation of GABA binding to rat brain membranes by alkyl beta-carboline-3-carboxylate esters.
    European journal of pharmacology, 1982, Dec-24, Volume: 86, Issue:2

    Topics: Animals; Brain; Carbolines; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Membranes; Rats

1982
Cardiovascular neurons in cat caudal ventrolateral medulla: location and characterization of GABAergic input.
    Brain research, 1995, Sep-25, Volume: 693, Issue:1-2

    Topics: Animals; Antibody Specificity; Blood Pressure; Carbolines; Cardiovascular System; Cats; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Ligands; Male; Medulla Oblongata; Microinjections; Muscimol; Neural Pathways; Neurons; Phenylethanolamine N-Methyltransferase; Picrotoxin; Tyrosine 3-Monooxygenase

1995
Enhancement of GABA-activated current by muscarine in rat dorsal root ganglion neurons.
    Neuroscience, 1999, Volume: 89, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Carbachol; Carbolines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Modulators; Gallamine Triethiodide; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channel Gating; Ion Channels; Male; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nerve Tissue Proteins; Nicotinic Antagonists; Patch-Clamp Techniques; Pentobarbital; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Muscarinic

1999