Page last updated: 2024-08-26

beta-carboline-3-carboxylic acid ethyl ester and beta-carboline-3-carboxylic acid methyl ester

beta-carboline-3-carboxylic acid ethyl ester has been researched along with beta-carboline-3-carboxylic acid methyl ester in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199020 (71.43)18.7374
1990's6 (21.43)18.2507
2000's2 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allen, MS; Cook, JM; Costantino, G; Dorn, LJ; Hagen, TJ; Koehler, KF; LaLoggia, AJ; Martin, MJ; Skolnick, P1
Allen, MS; Codding, PW; Hagen, TJ; Koehler, KF; Martin, MJ; Narayanan, K; Schindler, LR; Schultz, C; Tan, YC; Trudell, ML1
Chapouthier, G; Dodd, RH; Dorey, G; Poissonnet, G; Potier, MC; Potier, P; Prado de Carvalho, L; Rossier, J; Venault, P1
Allen, MS; Codding, PW; Cook, JM; Hagen, TJ; Skolnick, P; Trudell, ML1
Eigyo, M; Kawasaki, K; Matsushita, A; Murata, S; Sasatani, T; Shindo, H; Takada, S1
Barker, SA; Cain, M; Cook, JM; Crawley, JN; Guzman, F; Paul, SM; Rice, KC; Skolnick, P; Weber, RW1
Lippke, KP; Müller, WE; Schunack, WG; Wenning, W1
Cain, M; Cook, JM; Guzman, F; Hagen, T; Larscheid, P; Paul, SM; Schweri, M; Skolnick, P1
Good, AC; Peterson, SJ; Richards, WG1
Platt, DE; Silverman, BD1
Karplus, M; So, SS1
Ahmad, K; Beg, Y; Cho, SJ; Muddassar, M; Pasha, FA1
Clayton, T; Cook, J; DeLorey, TM; Furtmüller, R; Halliwell, RF; Harris, D; Huck, S; Sahbaie, P; Sieghart, W1
Claustre, Y; Dennis, T; Rivy, JP; Scatton, B1
Moura, D; Soares-da-Silva, P1
Chapouthier, G; de Carvalho, LP; Dodd, RH; Ouannès, C; Potier, P; Rossier, J; Valin, A; Venault, P1
Gardner, CR; James, V1
Sieghart, W1
Cook, JA; Guzman, F; Hagen, TJ; Shannon, HE1
Itonaga, M; Kubota, K; Uruno, T1
Itonaga, M; Kubota, K1
Macdonald, RL; Skerritt, JH1
Little, HJ1
Bonetti, EP; Haefely, W; Polc, P; Schaffner, R1
Paul, SM; Skolnick, P1
Barrett, JE; Martin, JV; Mendelson, WB; Paul, SM; Schweri, MM; Skolnick, P1
Martin, JV; Mendelson, WB; Paul, SM; Schweri, MM; Skolnick, P; Wagner, RL1
Estupinan, LE; France, CP; Gerak, LR1

Reviews

1 review(s) available for beta-carboline-3-carboxylic acid ethyl ester and beta-carboline-3-carboxylic acid methyl ester

ArticleYear
[Drug activation of GABAergic transmission in the central nervous system: benzodiazepines and GABAergic agonists].
    Acta medica portuguesa, 1985, Volume: 6, Issue:2

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Chemical Phenomena; Chemistry; Cyclic GMP; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Humans; Receptors, GABA-A; Synaptic Transmission; Valproic Acid

1985

Other Studies

27 other study(ies) available for beta-carboline-3-carboxylic acid ethyl ester and beta-carboline-3-carboxylic acid methyl ester

ArticleYear
Predictive binding of beta-carboline inverse agonists and antagonists via the CoMFA/GOLPE approach.
    Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22

    Topics: Animals; Binding, Competitive; Carbolines; Cerebral Cortex; Convulsants; GABA-A Receptor Antagonists; In Vitro Techniques; Male; Mice; Models, Molecular; Models, Statistical; Molecular Conformation; Rats; Receptors, GABA-A; Regression Analysis; Structure-Activity Relationship

1992
Synthetic and computer-assisted analyses of the pharmacophore for the benzodiazepine receptor inverse agonist site.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:9

    Topics: Binding Sites; Carbolines; Chemical Phenomena; Chemistry; Computer Simulation; Ligands; Models, Chemical; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship

1990
Synthesis and benzodiazepine receptor affinities of rigid analogues of 3-carboxy-beta-carbolines: demonstration that the benzodiazepine receptor recognizes preferentially the s-cis conformation of the 3-carboxy group.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:8

    Topics: Animals; Carbolines; Chemical Phenomena; Chemistry; In Vitro Techniques; Mice; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship

1989
Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:9

    Topics: Animals; Carbolines; Chemical Phenomena; Chemistry; Diazepam; Hydrogen Bonding; Indoles; Mice; Pyridines; Receptors, GABA-A; Structure-Activity Relationship

1988
A new thienylpyrazoloquinoline: a potent and orally active inverse agonist to benzodiazepine receptors.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:3

    Topics: Administration, Oral; Animals; Anticonvulsants; Indicators and Reagents; Male; Mice; Pentylenetetrazole; Pyrazoles; Quinolines; Receptors, GABA-A; Seizures; Thiophenes

1987
Beta-carbolines: synthesis and neurochemical and pharmacological actions on brain benzodiazepine receptors.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:9

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Carbolines; Chemical Phenomena; Chemistry; Diazepam; Drug Interactions; Indoles; Male; Mice; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A

1982
beta-Carbolines as benzodiazepine receptor ligands. 1. Synthesis and benzodiazepine receptor interaction of esters of beta-carboline-3-carboxylic acid.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:4

    Topics: Animals; Carbolines; Cattle; Cerebral Cortex; Indoles; Receptors, Cell Surface; Receptors, GABA-A

1983
Biomimetic approach to potential benzodiazepine receptor agonists and antagonists.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:5

    Topics: Animals; Benzodiazepines; Cell Membrane; Cerebral Cortex; Diazepam; Indicators and Reagents; Rats; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship

1984
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.
    Journal of medicinal chemistry, 1993, Oct-01, Volume: 36, Issue:20

    Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship

1993
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.
    Journal of medicinal chemistry, 1996, May-24, Volume: 39, Issue:11

    Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone

1996
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Cholinesterase Inhibitors; Dopamine beta-Hydroxylase; Drug Design; Enzyme Inhibitors; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Conformation; Molecular Structure; Neural Networks, Computer; Phosphorylases; Receptors, Aryl Hydrocarbon; Static Electricity; Structure-Activity Relationship

1997
3D and quantum QSAR of non-benzodiazepine compounds.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:11

    Topics: Benzodiazepines; Carbolines; Imaging, Three-Dimensional; Imidazoles; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Pyrimidines; Quantitative Structure-Activity Relationship; Software

2008
Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Animals; Behavior, Animal; Benzodiazepines; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Databases, Factual; Electrophysiology; Female; Ligands; Male; Memory; Mice; Models, Molecular; Molecular Structure; Oocytes; Protein Isoforms; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis

2008
Pharmacological studies on stress-induced increase in frontal cortical dopamine metabolism in the rat.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Carbolines; Dopamine; Electroshock; Fear; Frontal Lobe; Male; Pyridines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, GABA-A; Stress, Physiological; Swimming; Zolpidem

1986
3-Amino-beta-carboline derivatives and the benzodiazepine receptor. Synthesis of a selective antagonist of the sedative action of diazepam.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:6

    Topics: Animals; Carbolines; Convulsants; Diazepam; In Vitro Techniques; Indoles; Male; Mice; Papio; Rats; Rats, Inbred Strains; Receptors, GABA-A; Structure-Activity Relationship

1985
Actions and interactions of benzodiazepine agonists, antagonists and inverse agonists on suprahyoid muscle twitching.
    European journal of pharmacology, 1985, Jul-17, Volume: 113, Issue:2

    Topics: Amphetamine; Animals; Benzodiazepines; Carbolines; In Vitro Techniques; Male; Muscle Contraction; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A

1985
Benzodiazepine receptors: multiple receptors or multiple conformations?
    Journal of neural transmission, 1985, Volume: 63, Issue:3-4

    Topics: Animals; Binding Sites; Brain; Brain Chemistry; Carbolines; Chemical Phenomena; Chemistry; Flunitrazepam; Humans; Kinetics; Models, Chemical; Molecular Conformation; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A

1985
Beta-carbolines as antagonists of the discriminative stimulus effects of diazepam in rats.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1

    Topics: Animals; Carbolines; Diazepam; Discrimination Learning; Harmine; Male; Picrotoxin; Rats; Rats, Inbred F344

1988
Cholecystokinin antagonism by beta-carboline esters in the central nervous system in mice.
    Japanese journal of pharmacology, 1988, Volume: 46, Issue:4

    Topics: Animals; Brain; Carbolines; Cholecystokinin; Eating; Male; Mice; Mice, Inbred Strains; Morphine; Nociceptors; Pain; Time Factors

1988
Beta-carbolines selectively antagonize the cholecystokinin action in isolated guinea-pig gallbladder muscle.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:4

    Topics: Alkylation; Animals; Carbolines; Cholecystokinin; Dibenzylchlorethamine; Dose-Response Relationship, Drug; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Receptors, Cholecystokinin

1986
Benzodiazepine receptor ligand actions on GABA responses. Beta-carbolines, purines.
    European journal of pharmacology, 1984, May-18, Volume: 101, Issue:1-2

    Topics: Animals; Carbolines; Cells, Cultured; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Indoles; Ligands; Mice; Neurons; Purines; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord

1984
The effects of benzodiazepine agonists, inverse agonists and Ro 15-1788 on the responses of the superior cervical ganglion to GABA in vitro.
    British journal of pharmacology, 1984, Volume: 83, Issue:1

    Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Carbolines; Chlordiazepoxide; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Sympathetic; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A

1984
A three-state model of the benzodiazepine receptor explains the interactions between the benzodiazepine antagonist Ro 15-1788, benzodiazepine tranquilizers, beta-carbolines, and phenobarbitone.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 321, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Carbolines; Cats; Female; Flumazenil; Hippocampus; In Vitro Techniques; Indoles; Male; Mice; Models, Biological; Phenobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord

1982
New concepts in the neurobiology of anxiety.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:11 Pt 2

    Topics: Animals; Anxiety; Barbiturates; Behavior; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Carbolines; Central Nervous System; Flumazenil; Humans; Macaca mulatta; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A

1983
Pharmacokinetic and pharmacodynamic factors contributing to the convulsant action of beta-carboline-3-carboxylic acid esters.
    Life sciences, 1983, Oct-10, Volume: 33, Issue:15

    Topics: Animals; Brain; Carbolines; Convulsants; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Indoles; Kinetics; Male; Rats; Rats, Inbred Strains; Saimiri

1983
3-carboethoxy-beta-carboline (beta-CCE) elicits electroencephalographic seizures in rats: reversal by the benzodiazepine antagonist CGS 8216.
    Life sciences, 1983, May-23, Volume: 32, Issue:21

    Topics: Animals; Benzodiazepines; Brain; Carbolines; Electroencephalography; Indoles; Male; Pyrazoles; Rats; Rats, Inbred Strains; Seizures

1983
Ventilatory effects of negative GABA(A) modulators in rhesus monkeys.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 61, Issue:4

    Topics: Animals; Azides; Benzodiazepines; Carbolines; Diazepam; Female; GABA Modulators; Macaca mulatta; Male; Receptors, GABA-A; Respiration, Artificial

1998