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beta-carboline-3-carboxylic acid ethyl ester and 3-ethoxy-beta-carboline

beta-carboline-3-carboxylic acid ethyl ester has been researched along with 3-ethoxy-beta-carboline in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's6 (54.55)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allen, MS; Cook, JM; Costantino, G; Dorn, LJ; Hagen, TJ; Koehler, KF; LaLoggia, AJ; Martin, MJ; Skolnick, P1
Allen, MS; Codding, PW; Hagen, TJ; Koehler, KF; Martin, MJ; Narayanan, K; Schindler, LR; Schultz, C; Tan, YC; Trudell, ML1
Allen, MS; Codding, PW; Cook, JM; Hagen, TJ; Skolnick, P; Trudell, ML1
Good, AC; Peterson, SJ; Richards, WG1
Platt, DE; Silverman, BD1
Karplus, M; So, SS1
Cook, JM; Cox, ED; Diaz-Arauzo, H; Harris, B; Huang, Q; Ma, C; McKernan, R; Reddy, MS; Skolnick, P1
Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S1
Ahmad, K; Beg, Y; Cho, SJ; Muddassar, M; Pasha, FA1
Clayton, T; Cook, J; DeLorey, TM; Furtmüller, R; Halliwell, RF; Harris, D; Huck, S; Sahbaie, P; Sieghart, W1
Clayton, T; Cook, JM; Cromer, BA; Ma, C; Majumder, S; Namjoshi, OA; Petrou, S; Platt, DM; Roth, BL; VanLinn, ML; Yin, W1

Other Studies

11 other study(ies) available for beta-carboline-3-carboxylic acid ethyl ester and 3-ethoxy-beta-carboline

ArticleYear
Predictive binding of beta-carboline inverse agonists and antagonists via the CoMFA/GOLPE approach.
    Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22

    Topics: Animals; Binding, Competitive; Carbolines; Cerebral Cortex; Convulsants; GABA-A Receptor Antagonists; In Vitro Techniques; Male; Mice; Models, Molecular; Models, Statistical; Molecular Conformation; Rats; Receptors, GABA-A; Regression Analysis; Structure-Activity Relationship

1992
Synthetic and computer-assisted analyses of the pharmacophore for the benzodiazepine receptor inverse agonist site.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:9

    Topics: Binding Sites; Carbolines; Chemical Phenomena; Chemistry; Computer Simulation; Ligands; Models, Chemical; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship

1990
Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:9

    Topics: Animals; Carbolines; Chemical Phenomena; Chemistry; Diazepam; Hydrogen Bonding; Indoles; Mice; Pyridines; Receptors, GABA-A; Structure-Activity Relationship

1988
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.
    Journal of medicinal chemistry, 1993, Oct-01, Volume: 36, Issue:20

    Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship

1993
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.
    Journal of medicinal chemistry, 1996, May-24, Volume: 39, Issue:11

    Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone

1996
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Cholinesterase Inhibitors; Dopamine beta-Hydroxylase; Drug Design; Enzyme Inhibitors; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Conformation; Molecular Structure; Neural Networks, Computer; Phosphorylases; Receptors, Aryl Hydrocarbon; Static Electricity; Structure-Activity Relationship

1997
Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423)
    Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Binding, Competitive; Carbolines; Cell Line; Cerebral Cortex; Drug Design; GABA Agonists; Humans; Male; Mice; Muscle Relaxation; Rats; Receptors, GABA-A; Recombinant Proteins; Seizures; Structure-Activity Relationship

1998
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
    Journal of medicinal chemistry, 2000, Jan-13, Volume: 43, Issue:1

    Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship

2000
3D and quantum QSAR of non-benzodiazepine compounds.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:11

    Topics: Benzodiazepines; Carbolines; Imaging, Three-Dimensional; Imidazoles; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Pyrimidines; Quantitative Structure-Activity Relationship; Software

2008
Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Animals; Behavior, Animal; Benzodiazepines; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Databases, Factual; Electrophysiology; Female; Ligands; Male; Memory; Mice; Models, Molecular; Molecular Structure; Oocytes; Protein Isoforms; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis

2008
Design, synthesis, and subtype selectivity of 3,6-disubstituted β-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Alcoholism; Animals; Benzodiazepines; Binding Sites; Carbolines; Cell Line; Computer Simulation; GABA-A Receptor Antagonists; Humans; Protein Subunits; Rats; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship

2010