beta-alanine and uracil

beta-alanine has been researched along with uracil in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199014 (40.00)18.7374
1990's6 (17.14)18.2507
2000's8 (22.86)29.6817
2010's5 (14.29)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Abeling, NG; Busch, S; Scholten, EG; Stroomer, LE; van Gennip, AH1
Engelbrecht, C; Yngner, T1
Furusawa, M; Hara, Y; Kono, A1
Kraal, I; Lankelma, J; Laurensse, E; Leyva, A; Peters, GJ; Pinedo, HM; van Groeningen, CJ1
O'Donovan, GA; Shanley, MS; Traut, TW; West, TP1
Cha, S; el Kouni, MH; Naguib, FN1
Fujimoto, S; Mizota, C; Mizutani, N; Tamaki, N1
Haruno, A; Kunimune, Y; Morita, K; Unemi, N; Yamamoto, J; Yamashita, K; Yoshimura, Y1
Loechel, S; Traut, TW1
Cronan, JE1
O'Donovan, GA; Shanley, MS; West, TP1
Funatsuka, A; Kubo, K; Tamaki, N1
Baccanari, DP; Davis, ST; Joyner, SS; Spector, T1
Fujimoto, S; Kaneko, M; Kikugawa, M; Kontani, Y; Tamaki, N1
Jones, ME; Traut, TW1
Beigelman, L; Handschumacher, RE; Levy, E; Liu, MP; Pizzorno, G1
Van Gennip, AH; Van Kuilenburg, AB; Van Lenthe, H1
Hirakawa, Y; Kawaguchi, Y; Kuwata, K; Matsushima, E; Nagayama, S1
Goto, M; Hamaguchi, T; Matsumura, Y; Muro, K; Nagayama, S; Shimada, Y; Shirao, K; Yamada, Y1
GRISOLIA, S; WALLACH, DP1
FRITZSON, P1
FRITZSON, P; PIHL, A1
Abeling, NG; Stroomer, AE; Van Gennip, AH; Van Kuilenburg, AB; Van Lenthe, H1
Carr, AM; Caspari, T; Sauer, N; Stolz, J1
Hoffmann, GF; Hofmann, U; Kohlmüller, D; Mürdter, T; Schmidt, C; Schwab, M; Zanger, UM1
Beijnen, JH; Bosch, TM; Jörger, M; Schellens, JH; Sparidans, RW1
Yamada, Y1
Hanauske, A; Hilger, RA; Krauss, J; Kredtke, S; Makris, L; Mende, B; Scheulen, ME; Scigalla, P; Strumberg, D; Thyssen, D; Urrea, PD1
Amidon, GL; Provoda, CJ; Tsume, Y1
Liu, P; Song, W; Wang, F; Wu, C; Xiang, R; Yang, J; Yang, X; Yu, L1
Chen, JJ; Fu, YY; Huang, H; Li, Q; Liu, Z; Mu, J; Wei, YD; Xie, P; Yang, DY; Zheng, P; Zhou, CJ; Zhou, JJ1
Chung, M; Fitz-Gibbon, S; Fricke, RCB; Fukusaki, E; Laviña, WA; Liao, JC; Pellegrini, M; Pontrelli, S; Putri, SP; Teoh, ST1
Ang, EL; Hu, Y; Liu, D; Lu, Q; Wei, Y; Yin, J; Zhang, Y; Zhao, H1
Beltrán, LFL; Dávalos, A; García-de Los Santos, A; García-García, JD; López-Sámano, M; Sánchez-Thomas, R; Villaseñor, T1
Bretner, M; Grześkowiak, P; Ignatowska, J; Karatsai, O; Koszytkowska-Stawińska, M; Mironiuk-Puchalska, E; Rędowicz, MJ; Wielechowska, M; Wińska, P1

Reviews

1 review(s) available for beta-alanine and uracil

ArticleYear
Uracil metabolism--UMP synthesis from orotic acid or uridine and conversion of uracil to beta-alanine: enzymes and cDNAs.
    Progress in nucleic acid research and molecular biology, 1996, Volume: 53

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; beta-Alanine; Biological Evolution; DNA, Complementary; Humans; Molecular Sequence Data; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Peptide Synthases; Uracil; Uridine; Uridine Kinase; Uridine Monophosphate

1996

Other Studies

34 other study(ies) available for beta-alanine and uracil

ArticleYear
Simple method for the quantitative analysis of dihydropyrimidines and N-carbamyl-beta-amino acids in urine.
    Advances in experimental medicine and biology, 1991, Volume: 309B

    Topics: Amidohydrolases; Amino Acids; beta-Alanine; Chromatography, Ion Exchange; Humans; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrimidines; Thymine; Uracil

1991
Metabolism of uridine and determination of liver ribonucleic acid synthesis in developing and adult mice.
    The International journal of biochemistry, 1985, Volume: 17, Issue:4

    Topics: Aging; Alanine; Animals; beta-Alanine; Liver; Male; Mice; Orotic Acid; RNA; Tritium; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate

1985
[Effect of uracil on the both reactions, 5-fluorouracil degradation into 2-fluoro-beta-alanine and 5-fluorouracil splitting from tegafur in human tumor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 1

    Topics: Adenocarcinoma, Papillary; Alanine; beta-Alanine; Fluorouracil; Humans; Lung Neoplasms; Tegafur; Tumor Cells, Cultured; Uracil

1989
Effect of pyrimidine nucleosides on body temperatures of man and rabbit in relation to pharmacokinetic data.
    Pharmaceutical research, 1987, Volume: 4, Issue:2

    Topics: Animals; beta-Alanine; Body Temperature Regulation; Cytidine; Dose-Response Relationship, Drug; Fever; Humans; Pyrimidine Nucleotides; Rabbits; Uracil; Uridine; Uridine Phosphorylase

1987
A Salmonella typhimurium strain defective in uracil catabolism and beta-alanine synthesis.
    Journal of general microbiology, 1985, Volume: 131, Issue:5

    Topics: Alanine; beta-Alanine; Mutation; Salmonella typhimurium; Temperature; Transduction, Genetic; Uracil

1985
Enzymes of uracil catabolism in normal and neoplastic human tissues.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 1

    Topics: Amidohydrolases; beta-Alanine; Dihydrouracil Dehydrogenase (NAD+); Fluorouracil; Humans; Kinetics; Neoplasms; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Uracil

1985
Increased beta-aminoisobutyric acid in rat liver with 6-azauracil and its enantiomer.
    FEBS letters, 1985, Oct-21, Volume: 191, Issue:1

    Topics: Aminoisobutyric Acids; Animals; beta-Alanine; Liver; Male; Rats; Rats, Inbred Strains; Stereoisomerism; Thymine; Uracil

1985
Effect of coadministration of uracil on the toxicity of tegafur.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:2

    Topics: Animals; beta-Alanine; Cats; Dogs; Female; Fluorouracil; Heart Diseases; Lethal Dose 50; Male; Mice; Nervous System Diseases; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Tegafur; Uracil

1984
Pyrimidine catabolism: individual characterization of the three sequential enzymes with a new assay.
    Biochemistry, 1984, May-22, Volume: 23, Issue:11

    Topics: Amidohydrolases; Animals; beta-Alanine; Carbon Radioisotopes; Chromatography, Thin Layer; Dihydrouracil Dehydrogenase (NAD+); Kinetics; Liver; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pyrimidines; Rats; Tritium; Uracil

1984
Beta-alanine synthesis in Escherichia coli.
    Journal of bacteriology, 1980, Volume: 141, Issue:3

    Topics: Alanine; Aspartic Acid; beta-Alanine; Carboxy-Lyases; Chromosome Mapping; Escherichia coli; Genes; Glutamate Decarboxylase; Kinetics; Pantothenic Acid; Substrate Specificity; Uracil

1980
Improved colorimetric procedure for quantitating N-carbamoyl-beta-alanine with minimum dihydrouracil interference.
    Analytical biochemistry, 1982, May-15, Volume: 122, Issue:2

    Topics: Alanine; beta-Alanine; Colorimetry; Spectrophotometry; Uracil

1982
The in vivo decrease of beta-alanine-2-oxoglutarate aminotransferase activity caused by 6-azauracil and 5-fluorouracil.
    Journal of nutritional science and vitaminology, 1982, Volume: 28, Issue:5

    Topics: 4-Aminobutyrate Transaminase; Animals; beta-Alanine; Brain; Fluorouracil; gamma-Aminobutyric Acid; Liver; Male; Rats; Rats, Inbred Strains; Transaminases; Uracil

1982
5-Ethynyluracil (776C85): protection from 5-fluorouracil-induced neurotoxicity in dogs.
    Biochemical pharmacology, 1994, Jul-19, Volume: 48, Issue:2

    Topics: Animals; beta-Alanine; Central Nervous System Diseases; Dihydrouracil Dehydrogenase (NADP); Dogs; Dose-Response Relationship, Drug; Fluorouracil; Infusions, Intravenous; Male; Oxidoreductases; Uracil

1994
Identity of D-3-aminoisobutyrate-pyruvate aminotransferase with alanine-glyoxylate aminotransferase 2.
    Biochimica et biophysica acta, 1993, Feb-13, Volume: 1156, Issue:2

    Topics: Alanine; Alanine Transaminase; Animals; beta-Alanine; Fluorouracil; Kinetics; Liver; Precipitin Tests; Rats; Transaminases; Uracil

1993
Discrete roles of hepatocytes and nonparenchymal cells in uridine catabolism as a component of its homeostasis.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: Animals; beta-Alanine; Biological Transport; Cell Membrane; Dihydrouracil Dehydrogenase (NAD+); Homeostasis; Kinetics; Liver; Male; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Rats; Rats, Sprague-Dawley; Sodium; Uracil; Uridine; Uridine Phosphorylase

1998
A radiochemical assay for beta-ureidopropionase using radiolabeled N-carbamyl-beta-alanine obtained via hydrolysis of [2-(14)C]5, 6-dihydrouracil.
    Analytical biochemistry, 1999, Aug-01, Volume: 272, Issue:2

    Topics: Amidohydrolases; beta-Alanine; Carbon Dioxide; Carbon Radioisotopes; Humans; Hydrolysis; Kinetics; Liver; Radioisotope Dilution Technique; Reproducibility of Results; Scintillation Counting; Sensitivity and Specificity; Uracil

1999
[Comparison of pharmacokinetics of 5-FU and alpha-fluoro-beta-alanine, a metabolite of 5-FU, in plasma after administration of UFT, tegafur, 5-FU or doxifluridine to rats].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:6

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; beta-Alanine; Floxuridine; Fluorouracil; Male; Rats; Rats, Sprague-Dawley; Tegafur; Uracil

2000
Plasma concentrations of 5-fluorouracil and F-beta-alanine following oral administration of S-1, a dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, as compared with protracted venous infusion of 5-fluorouracil.
    British journal of cancer, 2003, Sep-01, Volume: 89, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; beta-Alanine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Enzyme Inhibitors; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Oxidoreductases; Oxonic Acid; Pyridines; Tegafur; Uracil

2003
Enzymic interconversion of hydrouracil and beta-ureidopropionic acid.
    Biochimica et biophysica acta, 1955, Volume: 18, Issue:3

    Topics: Alanine; beta-Alanine; Uracil

1955
The catabolism of C14-labeled uracil, dihydrouracil, and beta-ureidopropionic acid in rat liver slices.
    The Journal of biological chemistry, 1957, Volume: 226, Issue:1

    Topics: Alanine; Animals; beta-Alanine; Liver; Rats; Uracil; Urea

1957
The catabolism of C14-labeled uracil, dihydrouracil, and beta-ureidopropionic acid in the intact rat.
    The Journal of biological chemistry, 1957, Volume: 226, Issue:1

    Topics: Alanine; Animals; beta-Alanine; Rats; Uracil; Urea

1957
New insights in dihydropyrimidine dehydrogenase deficiency: a pivotal role for beta-aminoisobutyric acid?
    The Biochemical journal, 2004, Apr-01, Volume: 379, Issue:Pt 1

    Topics: Aminoisobutyric Acids; beta-Alanine; Brain Diseases, Metabolic, Inborn; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Homeostasis; Humans; Inactivation, Metabolic; Neurotransmitter Agents; Purine-Pyrimidine Metabolism, Inborn Errors; Stereoisomerism; Thymine; Uracil; Valine

2004
Cell division defects of Schizosaccharomyces pombe liz1- mutants are caused by defects in pantothenate uptake.
    Eukaryotic cell, 2004, Volume: 3, Issue:2

    Topics: beta-Alanine; Cell Division; Fungal Proteins; Gene Deletion; Genetic Complementation Test; Membrane Transport Proteins; Pantothenic Acid; Propionates; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Uracil

2004
Comprehensive analysis of pyrimidine metabolism in 450 children with unspecific neurological symptoms using high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:6

    Topics: Adolescent; beta-Alanine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Epilepsy; Exons; Female; Genotype; Humans; Infant; Infant, Newborn; Ions; Male; Mass Spectrometry; Models, Statistical; Mutation; Normal Distribution; Ornithine Carbamoyltransferase Deficiency Disease; Pyrimidines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Thymine; Uracil

2005
Liquid chromatography-tandem mass spectrometric assay for the analysis of uracil, 5,6-dihydrouracil and beta-ureidopropionic acid in urine for the measurement of the activities of the pyrimidine catabolic enzymes.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Jul-24, Volume: 839, Issue:1-2

    Topics: beta-Alanine; Biological Assay; Calibration; Capecitabine; Case-Control Studies; Child; Child, Preschool; Chromatography, Liquid; Deoxycytidine; Enzymes; Female; Fluorouracil; Humans; Infant, Newborn; Male; Pyrimidines; Spectrometry, Mass, Electrospray Ionization; Uracil

2006
[Plasma concentrations of 5-fluorouracil and F-beta-alanine following oral administration of S-1, a dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, as compared with protracted venous infusion of 5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: beta-Alanine; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fluorouracil; Humans; Infusions, Intravenous; Kidney; Oxonic Acid; Stomach Neoplasms; Tegafur; Uracil

2006
Pharmacokinetic study of S-1.
    International journal of clinical pharmacology and therapeutics, 2009, Volume: 47, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Anti-Ulcer Agents; Antimetabolites, Antineoplastic; Area Under Curve; beta-Alanine; Biological Availability; Clinical Trials as Topic; Dihydrouracil Dehydrogenase (NADP); Drug Combinations; Fasting; Fluorouracil; Food; Gastric Acidity Determination; Half-Life; Humans; Hydrogen-Ion Concentration; Oxonic Acid; Pantoprazole; Pyridines; Tegafur; Triazines; Uracil

2009
The achievement of mass balance by simultaneous quantification of floxuridine prodrug, floxuridine, 5-fluorouracil, 5-dihydrouracil, α-fluoro-β-ureidopropionate, α-fluoro-β-alanine using LC-MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Apr-15, Volume: 879, Issue:13-14

    Topics: Analysis of Variance; Antimetabolites, Antineoplastic; beta-Alanine; Cell Extracts; Cell Line, Tumor; Chromatography, High Pressure Liquid; Floxuridine; Fluorouracil; Humans; Linear Models; Mass Spectrometry; Reproducibility of Results; Uracil; Urea

2011
Uridine decreases morphine-induced behavioral sensitization by decreasing dorsal striatal dopamine release possibly via agonistic effects at GABAA receptors.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:9

    Topics: Analgesics, Opioid; Animals; Animals, Inbred Strains; beta-Alanine; Bicuculline; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Mice; Morphine; Motor Activity; Receptors, GABA-A; Time Factors; Uracil; Uridine

2014
Divergent Urinary Metabolic Phenotypes between Major Depressive Disorder and Bipolar Disorder Identified by a Combined GC-MS and NMR Spectroscopic Metabonomic Approach.
    Journal of proteome research, 2015, Aug-07, Volume: 14, Issue:8

    Topics: Adult; beta-Alanine; Biomarkers; Bipolar Disorder; Depressive Disorder, Major; Diagnosis, Differential; Female; Formates; Gas Chromatography-Mass Spectrometry; Humans; Hydroxybutyrates; Magnetic Resonance Spectroscopy; Male; Metabolome; Metabolomics; Phenylalanine; Propionates; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Young Adult

2015
Metabolic repair through emergence of new pathways in Escherichia coli.
    Nature chemical biology, 2018, Volume: 14, Issue:11

    Topics: beta-Alanine; Biosynthetic Pathways; Carboxy-Lyases; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Glutamate Decarboxylase; Malondialdehyde; Mutation; Ornithine Decarboxylase; Phenotype; Point Mutation; Polyamines; Spectrophotometry; Substrate Specificity; Uracil

2018
An extended bacterial reductive pyrimidine degradation pathway that enables nitrogen release from β-alanine.
    The Journal of biological chemistry, 2019, 10-25, Volume: 294, Issue:43

    Topics: Bacillaceae; Bacterial Proteins; beta-Alanine; Biocatalysis; Kinetics; Metabolic Networks and Pathways; Multigene Family; Nitrogen; Pyrimidines; Recombinant Proteins; Uracil

2019
A novel way to synthesize pantothenate in bacteria involves β-alanine synthase present in uracil degradation pathway.
    MicrobiologyOpen, 2020, Volume: 9, Issue:4

    Topics: Agrobacterium; Amidohydrolases; beta-Alanine; Carboxy-Lyases; Escherichia coli K12; Escherichia coli Proteins; Pantothenic Acid; Rhizobium; Uracil

2020
New insight into nucleo α-amino acids - Synthesis and SAR studies on cytotoxic activity of β-pyrimidine alanines.
    Bioorganic chemistry, 2020, Volume: 100

    Topics: Alanine; Antineoplastic Agents; beta-Alanine; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Models, Molecular; Pyrimidines; Uracil

2020