beta-alanine has been researched along with sc 57461 in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bible, R; Birkmeier, J; Hajdu, E; Hribar, JD; Liu, N; Rock, M; Schoenhard, G; Yang, DC; Yuan, JH | 1 |
| Penning, TD | 1 |
| Askonas, LJ; Kachur, JF; Liang, CD; Russell, MA; Smith, WG; Villani-Price, D | 1 |
| Askonas, LJ; Ghoreishi-Haack, N; Kachur, JF; Liang, CD; Russell, MA; Smith, WG; Villani-Price, D; Won-Kim, S | 1 |
| Askonas, LJ; Chen, BB; Chen, HY; Ghoreishi-Haack, NS; Gierse, JK; Harding, EI; Highkin, MK; Kachur, JF; Kim, SH; Liang, CD; Mahoney, MW; Malecha, JW; Miyashiro, JM; Penning, TD; Pyla, EY; Russell, MA; Smith, WG; Villani-Price, D; Yu, SS | 1 |
| Askonas, LJ; Chandrakumar, NS; Desai, BN; Djuric, SW; Gasiecki, AF; Ghoreishi-Haack, NS; Gierse, JK; Harding, EI; Highkin, MK; Kachur, JF; Kim, SH; Liang, CD; Miyashiro, JM; Penning, TD; Pyla, EY; Russell, MA; Smith, WG; Villani-Price, D | 1 |
| Borgeat, P; Bourgoin, SG; Flamand, N; Grenier, S; Naccache, PH; Pelletier, J | 1 |
| Bari, SB; Sonawane, LV | 1 |
| Akthar, S; Blalock, JE; Hare, SA; Jackson, PL; Lloyd, CM; Löser, S; Low, CM; Patel, DF; Snelgrove, RJ; Wong, CT | 1 |
| Chen, Q; Hang, CH; Li, W; Liu, JP; Lu, Y; Wu, LY; Xia, DY; Ye, ZN; Zhang, XS; Zhang, ZH; Zhou, ML; Zhuang, Z | 1 |
1 review(s) available for beta-alanine and sc 57461
| Article | Year |
|---|---|
Inhibitors of leukotriene A4 (LTA4) hydrolase as potential anti-inflammatory agents.
Topics: Amidines; Amino Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Alanine; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Imidazoles; Molecular Structure; Pyrrolidines; Zinc | 2001 |
9 other study(ies) available for beta-alanine and sc 57461
| Article | Year |
|---|---|
Isolation and identification of metabolites of leukotriene A4 hydrolase inhibitor SC-57461 in rats.
Topics: Administration, Oral; Animals; beta-Alanine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Epoxide Hydrolases; Infusions, Intravenous; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley | 1996 |
Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase I: in vitro studies.
Topics: Aminopeptidases; Animals; Arachidonic Acid; beta-Alanine; Chromatography, High Pressure Liquid; Dogs; Eicosanoids; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epoxide Hydrolases; Humans; In Vitro Techniques; Ionophores; Kinetics; Leukotriene A4; Leukotriene Antagonists; Macaca mulatta; Mice; Rats; Recombinant Proteins; Species Specificity; Substrate Specificity | 2002 |
Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase II: in vivo studies.
Topics: Administration, Oral; Administration, Topical; Animals; Arthus Reaction; beta-Alanine; Dermatitis; Edema; Eicosanoids; Enzyme Inhibitors; Epoxide Hydrolases; Hydroxyurea; In Vitro Techniques; Leukotriene A4; Leukotriene Antagonists; Lipoxygenase Inhibitors; Mice; Peritoneum; Rats; Skin | 2002 |
Synthesis of potent leukotriene A(4) hydrolase inhibitors. Identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid.
Topics: Administration, Oral; Animals; beta-Alanine; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Leukotriene A4; Mice; Structure-Activity Relationship | 2002 |
Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase.
Topics: Administration, Oral; Animals; beta-Alanine; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Inhibitory Concentration 50; Mice; Piperidines; Pyrrolidines; Structure-Activity Relationship | 2002 |
Arachidonic acid activates phospholipase D in human neutrophils; essential role of endogenous leukotriene B4 and inhibition by adenosine A2A receptor engagement.
Topics: ADP-Ribosylation Factor 1; Arachidonic Acid; Autocrine Communication; Benzopyrans; beta-Alanine; Biological Transport; Carboxylic Acids; Cell Membrane; Eicosapentaenoic Acid; Enzyme Activation; Epoxide Hydrolases; Humans; Indoles; Leukotriene Antagonists; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Phospholipase D; Protein Transport; Purinergic P1 Receptor Antagonists; Quinolines; Receptor, Adenosine A2A; Receptors, Leukotriene B4; Receptors, Purinergic P1; rhoA GTP-Binding Protein | 2003 |
QSAR, docking studies and pharmacophore identification of phenylmethyl phenoxy propyl amino propanoic acid derivatives as leukotriene A4 hydrolase inhibitors.
Topics: beta-Alanine; Catalytic Domain; Databases, Factual; Enzyme Inhibitors; Epoxide Hydrolases; Models, Molecular; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Software | 2010 |
The development of novel LTA
Topics: Amino Acid Motifs; Animals; Anti-Inflammatory Agents; beta-Alanine; Binding Sites; Bone Marrow Cells; Crystallography, X-Ray; Enzyme Inhibitors; Epoxide Hydrolases; Female; Gene Expression; Humans; Hydrolysis; Inflammation; Leukotriene B4; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Neutrophils; Oligopeptides; Proline; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity | 2017 |
Inhibition of leukotriene B4 synthesis protects against early brain injury possibly via reducing the neutrophil-generated inflammatory response and oxidative stress after subarachnoid hemorrhage in rats.
Topics: Animals; beta-Alanine; Blood-Brain Barrier; Brain Edema; Brain Injuries; Disease Models, Animal; Inflammation; Leukotriene B4; Male; Neutrophils; Oxidative Stress; Rats, Sprague-Dawley; Subarachnoid Hemorrhage | 2018 |