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beta, beta-dimethylacrylshikonin and naphthoquinones

beta, beta-dimethylacrylshikonin has been researched along with naphthoquinones in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's2 (8.70)18.2507
2000's2 (8.70)29.6817
2010's15 (65.22)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Guo, QX; Lin, ZB; Ruan, Y; Wang, P1
Chandra, B; Jacob, Z; Srivastava, OP; Tandon, RN; Wahab, S1
Chang, YS; Ko, FN; Kuo, SC; Lee, YS; Teng, CM1
Banaudha, KK; Gaddipati, JP; Maheshwari, RK; Patnaik, GK; Sidhu, GS; Singh, AK1
Chinou, I; Dobric, S; Fokialakis, N; Kletsas, D; Kovacevic, N; Kundakovic, T; Pratsinis, H1
Dou, G; Meng, Z; Sun, D; Tian, H; Yuan, D1
Chen, J; Chen, XJ; Ma, XY; Shao, ZJ; Wan, LH; Wu, YY; Zhou, LM; Zhu, L1
Gao, S; Li, N; Ren, R; Wang, Y; Xiao, Y; Zhang, H; Zhang, R1
Cheng, Y; Li, X; Xiao, S; Zeng, X; Zhang, Y1
Jian, C; Jiao, Y; Li-Ming, Z; Shao-Ju, J; Xiao-Wei, Z; Yao, X; Ying-Ying, F; Yuan-Yuan, Z; Zhen-Jun, S1
Chen, JH; Ma, XQ; Shen, XJ; Wang, HB1
Fan, Y; Feng, T; He, J; Jin, S; Li, H; Shao, Z; Yan, J1
Zeng, Z; Zhu, BH1
Ma, XQ; Wang, HB1
Gao, Q; Huang, WD; Liu, ZC; Su, ML; Yang, YF; Zeng, Z; Zhu, BH1
Arha, D; Mishra, A; Narender, T; Pandeti, S; Reddy, SS; Srivastava, AK; Tamrakar, AK1
Wang, H; Zhang, G2
Anders, I; Bauer, R; Deutsch, A; Durchschein, C; Jahanafrooz, Z; Kleinegger, F; Kretschmer, N; Lohberger, B; Rinner, B; Stallinger, A1
Bauer, R; Deutsch, A; Durchschein, C; Higareda-Almaraz, JC; Kretschmer, N; Lohberger, B; Rinner, B; Scheideler, M; Stallinger, A1
Ma, Y; Ren, X; Teng, L; Wang, T; Yang, M; Yang, W; Yao, H1
Bauer, R; Brvar, L; Deutsch, A; Durchschein, C; Kleinegger, F; Kretschmer, N; Liegl-Atzwanger, B; Prokesch, A; Rinner, B; Stallinger, A1
He, JM; Huang, J; Mu, Q; Wu, WL1

Other Studies

23 other study(ies) available for beta, beta-dimethylacrylshikonin and naphthoquinones

ArticleYear
[Anti-inflammatory effect of beta, beta-dimethylacrylshikonin (author's transl)].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1980, Volume: 1, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Female; Granuloma; Male; Naphthoquinones; Rats

1980
Comparative in vitro and in vivo effect of lactones and arnebins on Trichophyton mentagrophytes and Candida albicans.
    The Indian journal of medical research, 1982, Volume: 76 Suppl

    Topics: Animals; Candida albicans; Candidiasis; Guinea Pigs; Lactones; Naphthoquinones; Plant Extracts; Tinea; Trichophyton

1982
Inhibition on platelet activation by shikonin derivatives isolated from Arnebia euchroma.
    Biochimica et biophysica acta, 1995, Sep-21, Volume: 1268, Issue:3

    Topics: Animals; Anthraquinones; Blood Platelets; Calcium; Collagen; Cyclic AMP; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Naphthoquinones; Phosphatidylinositols; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rabbits; Thromboxane B2

1995
Arnebin-1 accelerates normal and hydrocortisone-induced impaired wound healing.
    The Journal of investigative dermatology, 1999, Volume: 113, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Epithelium; Fibronectins; Granulation Tissue; Hydrocortisone; Male; Naphthoquinones; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta; Wound Healing

1999
Evaluation of the anti-inflammatory and cytotoxic activities of naphthazarine derivatives from Onosma leptantha.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2006, Volume: 13, Issue:4

    Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Antineoplastic Agents; Biological Assay; Boraginaceae; Carrageenan; Cell Line, Tumor; Cyclohexanes; Edema; Humans; Indomethacin; Inhibitory Concentration 50; Male; Naphthoquinones; Plant Extracts; Plant Roots; Rats; Rats, Wistar

2006
Quantitative determination of beta,beta-dimethylacrylshikonin (DASK) in rat whole blood by liquid chromatography-tandem mass spectrometry with pre-column derivation and its pharmacokinetic application.
    Biomedical chromatography : BMC, 2009, Volume: 23, Issue:4

    Topics: Analytic Sample Preparation Methods; Animals; Carbazoles; Chromatography, Liquid; Naphthoquinones; Propionates; Rats; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2009
The anti-proliferation effect of Aikete injection on hepatocellular carcinoma in vitro and in vivo.
    Pharmaceutical biology, 2011, Volume: 49, Issue:5

    Topics: Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Genes, bcl-2; Humans; Injections; Liver Neoplasms; Male; Mice; Naphthoquinones

2011
Determination of the active constituents in Arnebia euchroma (Royle) Johnst. by ionic liquid-based ultrasonic-assisted extraction high-performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Jun-15, Volume: 879, Issue:20

    Topics: Boraginaceae; Chemical Fractionation; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ionic Liquids; Linear Models; Naphthoquinones; Reproducibility of Results; Sensitivity and Specificity; Sonication

2011
Ionization of shikonin derivatives using negative-ion electrospray mass spectrometry: [M-H]- versus [M + e]•-.
    Journal of mass spectrometry : JMS, 2012, Volume: 47, Issue:5

    Topics: Anthraquinones; Drugs, Chinese Herbal; Ions; Naphthoquinones; Pentanoic Acids; Spectrometry, Mass, Electrospray Ionization

2012
β,β-Dimethylacrylshikonin exerts antitumor activity via Notch-1 signaling pathway in vitro and in vivo.
    Biochemical pharmacology, 2012, Aug-15, Volume: 84, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drugs, Chinese Herbal; Female; G1 Phase; Humans; Mice; Mice, Inbred BALB C; Naphthoquinones; Receptor, Notch1; Resting Phase, Cell Cycle; Signal Transduction; Stomach Neoplasms; Transplantation, Heterologous

2012
β,β-Dimethylacrylshikonin induces mitochondria dependent apoptosis through ERK pathway in human gastric cancer SGC-7901 cells.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Mitochondria; Naphthoquinones; Signal Transduction; Stomach Neoplasms

2012
Effect of β,β-dimethylacrylshikonin on inhibition of human colorectal cancer cell growth in vitro and in vivo.
    International journal of molecular sciences, 2012, Volume: 13, Issue:7

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Humans; Male; Mice; Mice, Nude; Naphthoquinones; Proto-Oncogene Proteins c-bcl-2; Xenograft Model Antitumor Assays

2012
Arnebin-1 promotes the angiogenesis of human umbilical vein endothelial cells and accelerates the wound healing process in diabetic rats.
    Journal of ethnopharmacology, 2014, Jul-03, Volume: 154, Issue:3

    Topics: Alloxan; Animals; Cell Proliferation; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Male; Naphthoquinones; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Wound Healing

2014
β, β-Dimethylacrylshikonin induces mitochondria-dependent apoptosis of human lung adenocarcinoma cells in vitro via p38 pathway activation.
    Acta pharmacologica Sinica, 2015, Volume: 36, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Cell Line, Tumor; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mitochondria; Naphthoquinones; Signal Transduction

2015
Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway.
    International journal of molecular medicine, 2015, Volume: 36, Issue:3

    Topics: Angiogenesis Inducing Agents; Animals; Diabetes Complications; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Naphthoquinones; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Rats, Sprague-Dawley; Signal Transduction; Vascular Endothelial Growth Factor A; Wound Healing

2015
Glucose uptake stimulatory potential and antidiabetic activity of the Arnebin-1 from Arnabia nobelis.
    European journal of pharmacology, 2016, Oct-15, Volume: 789

    Topics: Animals; Biological Transport; Boraginaceae; Cell Line; Diabetes Mellitus, Experimental; Glucose; Glucose Transport Proteins, Facilitative; Hypoglycemic Agents; Mice; Muscle Fibers, Skeletal; Naphthoquinones; Phosphatidylinositol 3-Kinases; Rats; Signal Transduction

2016
Endoplasmic reticulum stress-mediated autophagy protects against β,β-dimethylacrylshikonin-induced apoptosis in lung adenocarcinoma cells.
    Cancer science, 2018, Volume: 109, Issue:6

    Topics: A549 Cells; Adenocarcinoma; Apoptosis; Autophagy; Autophagy-Related Protein 5; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum Stress; Humans; Lung Neoplasms; Naphthoquinones; RNA Interference; Signal Transduction; Transcription Factor CHOP; Unfolded Protein Response

2018
Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Oct-01, Volume: 49

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Boraginaceae; Caspase 3; Cell Line, Tumor; Cell Survival; Chordoma; Humans; Mitochondria; Naphthoquinones; Plant Roots; Signal Transduction; Silybin; Silymarin

2018
Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That
    Molecules (Basel, Switzerland), 2018, Oct-30, Volume: 23, Issue:11

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation; Humans; Melanoma; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Reactive Oxygen Species; Signal Transduction

2018
Protective role of arnebin-1 in rats with nonalcoholic fatty liver disease.
    The Journal of international medical research, 2019, Volume: 47, Issue:3

    Topics: Animals; Diet, High-Fat; Insulin Resistance; Liver Cirrhosis; Male; Naphthoquinones; Non-alcoholic Fatty Liver Disease; Protective Agents; Rats; Rats, Sprague-Dawley

2019
Activation of CaMKKβ-AMPK-mTOR pathway is required for autophagy induction by β,β-dimethylacrylshikonin against lung adenocarcinoma cells.
    Biochemical and biophysical research communications, 2019, 09-24, Volume: 517, Issue:3

    Topics: A549 Cells; Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Autophagy; Benzimidazoles; Boraginaceae; Calcium; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Egtazic Acid; Gene Expression Regulation, Neoplastic; Humans; Lithospermum; Methyltransferases; Naphthalimides; Naphthoquinones; Oxazines; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases

2019
β,β-Dimethylacrylshikonin Induces Apoptosis in Melanoma Cell Lines by NOXA Upregulation.
    Journal of natural products, 2020, 02-28, Volume: 83, Issue:2

    Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Humans; Melanoma; Mitochondria; Molecular Structure; Mutation; Naphthoquinones; Signal Transduction; Up-Regulation

2020
Unlimited recycling counter-current chromatography for the preparative separation of natural products: Naphthaquinones as examples.
    Journal of chromatography. A, 2020, Aug-30, Volume: 1626

    Topics: Biological Products; Countercurrent Distribution; Naphthoquinones; Pentanoic Acids

2020