berberrubine has been researched along with berberine in 50 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (2.00) | 18.2507 |
2000's | 10 (20.00) | 29.6817 |
2010's | 26 (52.00) | 24.3611 |
2020's | 13 (26.00) | 2.80 |
Authors | Studies |
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Czerniecki, NJ; Douglas, KA; Grundt, P; Krivogorsky, B; Pernat, JA | 1 |
Chung, IK; Kim, JH; Kim, SA; Kwon, Y; Muller, MT | 1 |
Hong, SW; Jeun, JA; Kim, JH; Kim, SH; Kim, SU; Lee, SJ | 1 |
Chung, IK; Kang, MR | 1 |
Kim, JH; Kim, SH; Lee, JH; Lee, SJ; Sun, WS | 1 |
Kang, TH; Kim, SH; Kim, SU; Lee, JH; Moon, JS; Park, KD | 1 |
Chi, ZL; Cui, HS; Hayasaka, S; Hayasaka, Y; Zhang, XY; Zheng, LS | 1 |
Akao, T; Hattori, M; Nakamura, N; Zuo, F | 1 |
Barthwal, R; Chauhan, L; Thankachan, PP; Tripathi, AN | 1 |
Ma, L; Yang, XW | 1 |
Apornpisarn, T; Nimgirawath, S; Taechowisan, T; Udomputtimekakul, P; Wanbanjob, A | 1 |
Jha, RN; Pandey, MB; Singh, AK; Singh, S; Singh, VP | 1 |
Deng, HB; Jiang, JD; Kong, WJ; Li, Y; Li, YH; Ren, G; Song, DQ; Wang, YM; Wang, YX; Yang, P; You, XF | 1 |
Dunnick, JK; Kissling, GE; Nyska, A; Peckham, J; Sanders, JM; Singh, B | 1 |
Jiang, JD; Kong, WJ; Li, Y; Li, YH; Li, ZR; Ren, G; Song, DQ; Wang, YM; Wang, YX; Yang, P; Yi, H | 1 |
Chen, JX; Chen, M; Chen, MZ; Chen, WH; Jiang, ZH; Lin, WE; Lin, YL; Zhou, CQ | 1 |
Basu, A; Jaisankar, P; Suresh Kumar, G | 1 |
Chen, SN; Feng, R; Fu, J; He, CY; He, WY; Huang, M; Jiang, JD; Ma, C; Ma, JY; Shou, JW; Tan, XS; Wang, Y; Zhao, ZX | 1 |
Chen, WJ; Feng, R; Fu, J; He, CY; He, WY; Huang, M; Jiang, JD; Ma, C; Ma, JY; Shou, JW; Sun, YP; Tan, XS; Wang, Y | 1 |
Bin, W; Cao, S; Kang, N; Qiu, F; Wang, Y; Xu, P; Yan, J; Zhou, Y | 1 |
Di, DL; Liu, JX; Ma, YX; Zhong, M | 1 |
Calvarese, C; Camborata, C; Colliva, C; Ianni, C; Lisotti, A; Mazzella, G; Neri, F; Roberti, M; Roda, A; Spinozzi, S | 1 |
Hai, L; He, Y; Li, R; Wu, J; Wu, Y | 1 |
Dai, GL; Feng, CT; Ju, WZ; Ma, ST; Miao, CG; Song, Y; Yu, H; Zhang, XL; Zhou, GL | 1 |
Bai, M; Jiang, H; Li, L; Song, F; Sun, S; Weng, Y; Zeng, S; Zhou, H; Zhou, S | 1 |
Chavasiri, W; Pongkittiphan, V; Supabphol, R | 1 |
Deng, M; Fan, M; Gao, Z; Hu, L; Lu, M; Ma, J; Wang, S; Wang, X; Ye, T | 1 |
Fukuda, M; Hosoe, T; Ishikawa, K; Sato, F; Takeda, H; Wakana, D | 1 |
Hosoe, T; Ishikawa, K; Sato, F; Takeda, H; Wakana, D | 1 |
Aa, J; Fei, F; Feng, S; Fu, F; Geng, J; Guo, J; He, J; Liao, X; Sun, R; Wang, G; Wang, H; Wang, J; Xie, Y; Yang, N; Zhao, Y; Zhen, L; Zhu, X | 1 |
Aa, JY; Chen, XL; Fei, F; Feng, SQ; Fu, FH; Ge, C; Geng, JL; Guo, JH; He, J; Sun, RB; Wang, GJ; Wang, HB; Yang, N; Yu, XY; Zhao, YQ; Zhen, L; Zhu, XX | 1 |
Chen, C; Lian, W; Liu, S; Shi, L; Su, R; Wan, D; Wang, Y; Xu, N; Yang, H; Yao, W | 1 |
Chandirasegaran, G; Elanchezhiyan, C; Ghosh, K; Sethupathy, S | 1 |
Cao, S; Chai, L; Ding, L; Feng, X; Qiao, M; Qiu, F; Wang, K | 1 |
Calabria, D; Caliceti, C; Franco, P; Porru, E; Roberti, M; Roda, A; Spinozzi, S | 1 |
Chen, JP; Huang, YF; Li, HL; Qu, C; Su, ZR; Xu, LQ; Xu, YF; Yi, TG; Yu, XT; Zeng, HF; Zhang, XJ; Zheng, L | 1 |
Bhuiya, S; Das, S; Fiorillo, G; Lombardi, P; Saha, U; Suresh Kumar, G; Yasmeen Khan, A | 1 |
Hosoe, T; Sato, F; Takeda, H; Wakana, D; Yoshida, H | 1 |
Choi, Y; Lin, H; Lin, L; Michniak-Kohn, B | 1 |
Ding, L; Gao, Q; Guang, C; Qiu, F; Rao, J; Wang, K; Zhang, J; Zhang, T | 1 |
Aa, J; Cao, B; Fei, F; Feng, D; Feng, S; Ge, C; Guo, GL; Huang, J; Kong, B; Lu, Z; Sun, R; Wang, G; Xie, Y; Yang, CS; Yang, N; Yu, X | 1 |
Chepanova, AA; Gladkova, ED; Ilina, ES; Lavrik, OI; Luzina, OA; Reynisson, J; Salakhutdinov, NF; Volcho, KP; Zakharenko, AL | 1 |
Ihmels, H; Wickhorst, PJ | 1 |
Cheng, JY; Hu, XW; Li, DD; Man, RJ; Zhang, MH | 1 |
Chang, JM; Chao, WY; Chen, SH; Chuang, HH; Kam, KH; Lee, YR; Li, YZ; Wu, JY; Yen, YP; Zhao, PW | 1 |
Hu, XW; Huang, J; Liu, FL; Man, RJ; Yuchi, XX; Zhang, MH | 1 |
Chen, J; Huang, Z; Jiang, L; Li, Y; Lin, G; Lin, Z; Liu, Y; Mai, L; Su, Z; Xie, J; Xu, L; Yu, Q | 1 |
Huang, J; Jiang, J; Kong, W; Lei, Y; Li, Y; Wang, C; Xie, J; Yuan, Z | 1 |
Abuduaini, N; Cui, J; Feng, B; He, X; Huang, J; Huang, Y; Lu, W; Ma, H; Tang, L; Wang, W; Wang, Y; Zhang, Y | 1 |
Boonyasuppayakorn, S; Chavasiri, W; Danova, A; Fujiki, R; Hengphasatporn, K; Nguyen, DV; Rungrotmongkol, T; Shigeta, Y; Suroengrit, A | 1 |
50 other study(ies) available for berberrubine and berberine
Article | Year |
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Structure-activity studies of some berberine analogs as inhibitors of Toxoplasma gondii.
Topics: Antiparasitic Agents; Berberine; Cells, Cultured; Inhibitory Concentration 50; Toxoplasma | 2012 |
Induction of topoisomerase II-mediated DNA cleavage by a protoberberine alkaloid, berberrubine.
Topics: Berberine; Berberine Alkaloids; Catalysis; DNA Damage; DNA Topoisomerases, Type II; DNA, Superhelical; Enzyme Activation; Etoposide; Humans; Intercalating Agents; Peptide Mapping; Plants, Medicinal; Topoisomerase II Inhibitors | 1998 |
Antimicrobial activity of 9-O-acyl- and 9-O-benzoyl-substituted berberrubines.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Berberine; Fungi; Microbial Sensitivity Tests; Molecular Structure; Plants, Medicinal | 2000 |
Down-regulation of DNA topoisomerase IIalpha in human colorectal carcinoma cells resistant to a protoberberine alkaloid, berberrubine.
Topics: Alkaloids; Antigens, Neoplasm; Antineoplastic Agents; Berberine; Colorectal Neoplasms; DNA Topoisomerases, Type II; DNA-Binding Proteins; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Half-Life; Humans; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured | 2002 |
Antimicrobial activity of 9-O-acyl- and 9-O-alkylberberrubine derivatives.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Berberine; Berberis; Fungi; Magnetic Resonance Spectroscopy; Plant Extracts; Quantitative Structure-Activity Relationship | 2002 |
Synthesis of 13-(substituted benzyl) berberine and berberrubine derivatives as antifungal agents.
Topics: Antifungal Agents; Aspergillus; Berberine; Candida; Cryptococcus neoformans; Microbial Sensitivity Tests | 2006 |
Effect of berberrubine on interleukin-8 and monocyte chemotactic protein-1 expression in human retinal pigment epithelial cell line.
Topics: Berberine; Cell Line; Chemokine CCL2; Gene Expression; Humans; Immunohistochemistry; Interleukin-1; Interleukin-8; Molecular Structure; Pigment Epithelium of Eye; Protein Transport; RNA, Messenger; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2006 |
Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry.
Topics: Animals; Bacteria; Berberine; Bile; Chromatography, Liquid; Germ-Free Life; Intestinal Absorption; Intestine, Small; Liver; Male; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2006 |
Quantum chemical and nuclear magnetic resonance spectral studies on molecular properties and electronic structure of berberine and berberrubine.
Topics: Antineoplastic Agents; Berberine; Carbon Isotopes; Computer Simulation; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Motion; Quantum Theory; Structure-Activity Relationship | 2007 |
[Absorption of coptisine chloride and berberrubine across human intestinal epithelial by using human Caco-2 cell monolayers].
Topics: Absorption; Berberine; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Corydalis; Epithelial Cells; Humans; Intestinal Mucosa; Plants, Medicinal | 2007 |
Total syntheses of (+/-)-gusanlung a, (+/-)-gusanlung D and 8-oxyberberrubine and the uncertainty concerning the structures of (-)-gusanlung A, (-)-gusanlung D and 8-oxyberberrubine.
Topics: Berberine; Candida albicans; Drugs, Chinese Herbal; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Staphylococcus aureus | 2009 |
New alkaloids from Corydalis species.
Topics: Alkaloids; Berberine; Bicuculline; Corydalis; Heterocyclic Compounds, 4 or More Rings; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Extracts | 2009 |
Design, synthesis, and cholesterol-lowering efficacy for prodrugs of berberrubine.
Topics: Animals; Anticholesteremic Agents; Berberine; Biological Availability; Cholesterol; Hyperlipidemias; Male; Prodrugs; Rats; Rats, Sprague-Dawley | 2010 |
Investigating the potential for toxicity from long-term use of the herbal products, goldenseal and milk thistle.
Topics: Animals; Berberine; Body Weight; Carcinogens; Female; Flavonolignans; Hydrastis; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Plant Preparations; Plant Roots; Rats; Rats, Inbred F344; Silybin; Silybum marianum; Silymarin; Topoisomerase Inhibitors; Toxicity Tests, Chronic | 2011 |
Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes.
Topics: AMP-Activated Protein Kinases; Animals; Berberine; Biotransformation; Cytochrome P-450 Enzyme System; Hep G2 Cells; Humans; Isoenzymes; Liver; Male; Metabolic Detoxication, Phase I; Rats; Rats, Wistar; Receptor, Insulin; Receptors, LDL | 2011 |
Synthesis, characterization and potent DNA-cleaving activity of copper(II)-complexed berberine carboxylate.
Topics: Berberine; Carboxylic Acids; Coordination Complexes; Copper; DNA; DNA Cleavage; Kinetics | 2012 |
Binding of the 9-O-N-aryl/arylalkyl amino carbonyl methyl substituted berberine analogs to tRNA(phe.).
Topics: Berberine; Binding Sites; Biophysical Phenomena; Nucleic Acid Conformation; RNA Stability; RNA, Fungal; RNA, Transfer, Phe; Thermodynamics | 2013 |
Excretion of berberine and its metabolites in oral administration in rats.
Topics: Administration, Oral; Animals; Berberine; Bile; Chromatography, High Pressure Liquid; Feces; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2013 |
Tissue distribution of berberine and its metabolites after oral administration in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Berberine; Chromatography, Liquid; Humans; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tissue Distribution | 2013 |
Berberine metabolites could induce low density lipoprotein receptor up-regulation to exert lipid-lowering effects in human hepatoma cells.
Topics: Berberine; Berberine Alkaloids; Berberis; Carcinoma, Hepatocellular; Coptis; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Hypolipidemic Agents; Lipid Metabolism; Lipoproteins, LDL; Liver Neoplasms; Plant Extracts; Receptors, LDL; RNA, Messenger; Up-Regulation | 2014 |
A new quaternary protoberberine alkaloid isolated from Dicranostigma leptopodum (Maxim) Fedde.
Topics: Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Papaveraceae | 2014 |
Berberine and its metabolites: relationship between physicochemical properties and plasma levels after administration to human subjects.
Topics: Administration, Oral; Adult; Alkaloids; Berberine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Female; Humans; Male; Molecular Structure | 2014 |
Synthesis and in vitro evaluation of 12-(substituted aminomethyl) berberrubine derivatives as anti-diabetics.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Berberine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Hypoglycemic Agents; Insulin Resistance; Mice; Molecular Structure; Muscle Fibers, Skeletal; Rats; Structure-Activity Relationship | 2014 |
In silico target fishing for the potential bioactive components contained in Huanglian Jiedu Tang (HLJDD) and elucidating molecular mechanisms for the treatment of sepsis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Berberine; Dinoprostone; Drugs, Chinese Herbal; Humans; KB Cells; Platelet Membrane Glycoproteins; Protein Transport; Receptors, G-Protein-Coupled; Receptors, Thromboxane A2, Prostaglandin H2; Sepsis; Tetradecanoylphorbol Acetate | 2015 |
Interaction of six protoberberine alkaloids with human organic cation transporters 1, 2 and 3.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Berberine; Berberine Alkaloids; Cells, Cultured; Chromatography, Liquid; Dogs; Humans; Inhibitory Concentration 50; Madin Darby Canine Kidney Cells; Octamer Transcription Factor-3; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Polymorphism, Genetic; Tandem Mass Spectrometry | 2016 |
Antioxidant Effect of Berberine and its Phenolic Derivatives Against Human Fibrosarcoma Cells.
Topics: Antioxidants; Apoptosis; Berberine; Biomarkers; Biphenyl Compounds; Catalase; Cell Proliferation; Cells, Cultured; Fibrosarcoma; Gene Expression Profiling; Humans; Oxidation-Reduction; Phenols; Picrates; Plant Extracts; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase | 2015 |
Pharmacokinetics in rats and tissue distribution in mouse of berberrubine by UPLC-MS/MS.
Topics: Administration, Intravenous; Administration, Oral; Animals; Berberine; Biological Availability; Calibration; Chromatography, Liquid; Drug Stability; Limit of Detection; Linear Models; Male; Mice; Models, Biological; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tissue Distribution | 2015 |
11-Hydroxylation of Protoberberine by the Novel Berberine-Utilizing Aerobic Bacterium Sphingobium sp. Strain BD3100.
Topics: Benzoflavones; Berberine; Berberine Alkaloids; Cytochrome P-450 Enzyme Inhibitors; Hydroxylation; Japan; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Sphingomonadaceae | 2015 |
Isolation and identification of berberine and berberrubine metabolites by berberine-utilizing bacterium Rhodococcus sp. strain BD7100.
Topics: Berberine; Berberine Alkaloids; Biotransformation; Culture Media; Phenylacetates; Rhodococcus | 2016 |
High fat diet aggravates the nephrotoxicity of berberrubine by influencing on its pharmacokinetic profile.
Topics: Animals; Anti-Obesity Agents; Berberine; Cell Line; Cell Survival; Diet, High-Fat; Humans; Kidney; Kidney Function Tests; Lipids; Male; Mice, Inbred C57BL; Renal Insufficiency | 2016 |
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-β-D-glucuronide, an active metabolite of berberrubine.
Topics: Animals; Berberine; Glucuronides; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Mice, Inbred C57BL; Rats, Sprague-Dawley | 2017 |
High-throughput screening of triplex DNA binders from complicated samples by 96-well pate format in conjunction with peak area-fading UHPLC-Orbitrap MS.
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; DNA; High-Throughput Screening Assays; Mass Spectrometry; Phellodendron; Reproducibility of Results | 2017 |
Berberine chloride ameliorates oxidative stress, inflammation and apoptosis in the pancreas of Streptozotocin induced diabetic rats.
Topics: Animals; Antioxidants; Apoptosis; Berberine; Blood Glucose; Diabetes Mellitus, Experimental; Inflammation; Male; Oxidative Stress; Pancreas; Rats; Rats, Wistar; Streptozocin | 2017 |
Identification of berberrubine metabolites in rats by using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.
Topics: Administration, Oral; Animals; Berberine; Bile; Chromatography, High Pressure Liquid; Feces; Male; Mass Spectrometry; Metabolome; Plasma; Rats; Rats, Sprague-Dawley | 2018 |
Combined analytical approaches to define biodistribution and biological activity of semi-synthetic berberrubine, the active metabolite of natural berberine.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Berberine; Berberis; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Male; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tissue Distribution; Xanthine Oxidase | 2018 |
Berberrubine attenuates mucosal lesions and inflammation in dextran sodium sulfate-induced colitis in mice.
Topics: Animals; Berberine; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Inflammation; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; Peroxidase; Tight Junction Proteins; Tight Junctions | 2018 |
Targeting human telomeric DNA quadruplex with novel berberrubine derivatives: insights from spectroscopic and docking studies.
Topics: Algorithms; Berberine; Calorimetry; Circular Dichroism; G-Quadruplexes; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Spectrum Analysis; Structure-Activity Relationship; Telomere | 2019 |
Identification of a multi-component berberine 11-hydroxylase from
Topics: Bacterial Proteins; Berberine; Berberine Alkaloids; Burkholderia; Escherichia coli; Ferredoxins; Genome, Bacterial; Hydroxylation; Microorganisms, Genetically-Modified; Mixed Function Oxygenases; Oxidoreductases; Phylogeny; Recombinant Proteins | 2020 |
Development and in-vitro evaluation of co-loaded berberine chloride and evodiamine ethosomes for treatment of melanoma.
Topics: Animals; Berberine; Drug Delivery Systems; Drug Development; Female; Humans; Liposomes; Melanoma, Experimental; Mice; Middle Aged; Plant Extracts; Quinazolines; Skin Absorption | 2020 |
Metabolic Activation and Covalent Protein Binding of Berberrubine: Insight into the Underlying Mechanism Related to Its Hepatotoxicity.
Topics: Activation, Metabolic; Animals; Berberine; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Liver; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Molecular Structure; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2020 |
The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis.
Topics: Animals; Berberine; Blood Glucose; Diet, High-Fat; Gluconeogenesis; Hypoglycemic Agents; Ileum; Liver; Male; Mice; Mice, Inbred C57BL; Protein Structure, Secondary; Receptors, Cytoplasmic and Nuclear; Signal Transduction | 2021 |
Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors.
Topics: Antineoplastic Agents; Berberine; Drug Design; HeLa Cells; Humans; Models, Molecular; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Structure-Activity Relationship | 2021 |
Berberrubine Phosphate: A Selective Fluorescent Probe for Quadruplex DNA.
Topics: Berberine; DNA; Fluorescent Dyes; Fluorometry; G-Quadruplexes; Molecular Structure; Nucleic Acid Denaturation; Phosphates; Spectrum Analysis; Structure-Activity Relationship; Temperature | 2021 |
A berberrubine-derived fluorescent probe for hydrazine and its practical application in water and food samples.
Topics: Berberine; Fluorescent Dyes; Hydrazines; Water | 2021 |
9-O-Terpenyl-Substituted Berberrubine Derivatives Suppress Tumor Migration and Increase Anti-Human Non-Small-Cell Lung Cancer Activity.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Berberine; Bromides; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Humans; Terpenes | 2021 |
A fluorescent probe derived from Berberrubine for detecting hydrogen polysulfide in food samples.
Topics: Berberine; Fluorescent Dyes; Hydrogen; Sulfides | 2022 |
Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Berberine; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Creatinine; Cytokines; Disease Models, Animal; Glucose Transport Proteins, Facilitative; Hyperuricemia; Hypoxanthine; Janus Kinase 2; Kidney Diseases; Male; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Oxonic Acid; Protective Agents; Signal Transduction; STAT3 Transcription Factor; Uric Acid; Xanthine Oxidase | 2021 |
Integrated metabolomics and molecular docking reveal berberrubine inhibits thrombosis by regulating the vitamin K catalytic cycle in mice.
Topics: Animals; Berberine; Carrageenan; Fibrinolytic Agents; GTPase-Activating Proteins; Mice; Molecular Docking Simulation; Thrombosis; Vitamin K; Vitamin K Epoxide Reductases | 2023 |
Berberrubine is a novel and selective IMPDH2 inhibitor that impairs the growth of colorectal cancer.
Topics: Animals; Berberine; Cell Line; Colorectal Neoplasms; Humans; IMP Dehydrogenase; Mice; Protein Isoforms | 2023 |
Structure-yeast α-glucosidase inhibitory activity relationship of 9-O-berberrubine carboxylates.
Topics: alpha-Glucosidases; Benzoates; Berberine; Glycoside Hydrolase Inhibitors; Kinetics; Molecular Docking Simulation; Molecular Structure; Saccharomyces cerevisiae; Structure-Activity Relationship | 2023 |