berberine and palmatine

berberine has been researched along with palmatine in 166 studies

Research

Studies (166)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (4.22)	18.7374
1990's	14 (8.43)	18.2507
2000's	56 (33.73)	29.6817
2010's	78 (46.99)	24.3611
2020's	11 (6.63)	2.80

Authors

Authors	Studies
Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y	1
Kim, JH; Kim, YH; Lee, WS; Ryu, YB	1
Bae, GU; Jeong, JH; Lee, H; Lee, SJ; Ryu, JH; Tuong, LT	1
Gastaldello, J; Grimm, SK; Kolodzik, A; Mracek, P; Nasiri, HR; Ullmann, D	1
Andrisano, V; Cahlikova, L; Hostalkova, A; Hulcova, D; Jun, D; Korabecny, J; Kucera, T; Kunes, J; Marikova, J; Novakova, L; Opletal, L; Perez, DI; Siatka, T	1
Fu, DJ; Li, J; Yu, B	1
Cheng, Y; Fan, T; Guo, X; Guo, Z; Jiang, J; Kong, W; Li, Y; Shi, Y; Song, D; Wang, Y; Wei, W; Zeng, Q; Zhang, X; Zhao, L	1
Ma, Y; Tang, X; Zhang, Z; Zhou, R	1
Fang, XP; Li, D; Shuai, H; Wang, TZ; Xie, CK; Zhang, H	1
An, DK; Dong, SS; Lin, SL; Wang, YM; Zhao, LB	1
Klayman, DL; Vennerstrom, JL	1
Lassila, V; Mengata, DE; Njimi, T; Virtanen, P	1
Chen, BL; Qiu, XX; Wu, CY	1
Kakizawa, S; Misaki, T; Ojima, M; Oshima, T; Sagara, K; Yoshizawa, H	1
Hatanaka, T; Kadota, S; Katayama, K; Koizumi, T; Namba, T; Sekiya, K; Toshinal, A	1
Chou, CC; Kuo, CL; Yung, BY	1
Cai, J; Henion, J; Hsieh, FY	1
Lin, QL; Xie, PS; Yan, YZ	1
Lin, SJ; Suen, TT; Tseng, HH; Wen, KC	1
Latz-Brüning, B; Schmeller, T; Wink, M	1
Iwasa, K; Kamigauchi, M; Nanba, H; Sugiura, M	1
Chao, R; Chen, J; Li, X; Zhang, H; Zhuang, Y	1
Adams, DJ; Johng, TN; Kang, KC; Kim, JH; Paik, YK; Park, KS	1
Ishida, S; Miki, H; Okamura, N; Ono, H; Ono, Y; Tanaka, T; Yagi, A; Yano, A	1
Ahn, YJ; Chae, SH; Choi, DH; Jeong, IH; Oh, JW	1
Chen, YR; Her, GR; Wen, KC	1
Eom, DO; Eom, YE; Lee, HS	1
Kai, M; Kim, EI; Lee, MK; Shin, JS	1
Ahn, YJ; Lee, HS; Lee, SG; Park, IK; Park, JD	1
Hu, JP; Takahashi, N; Yamada, T	1
Iwasa, K; Lee, DU; Moriyasu, M; Turuo, T; Wiegrebe, W; Yamori, T	1
Deng, Y; Dong, Y; Qiu, X; Yang, L	1
Lee, KS; Lee, MK; Lee, SS; Ro, JS	1
Lewis, K; Muntyan, MS; Severina, II; Skulachev, VP	1
Wei, L; Yang, D; Zhou, H	1
Inada, A; Muto, N; Nakanishi, T; Ootaki, K; Shigeta, K; Tatemoto, H	1
Ding, ZB; Guo, R; Kang, C; Wen, LY; Zhu, XS	1
Xu, HL	1
Chen, YR; Her, GR	1
Chen, LR; Chen, LX; Ma, JP; Wei, PH; Wei, YQ; Yuan, JR	1
Dostál, J; Hulová, D; Marek, J; Marek, R; Seckárová, P; Sklenár, V	1
Chen, T; Duan, TX; Li, Y; Lun, LH; Ma, CH; Okuma, R	1
Dai, KJ; Luo, JB; Luo, QZ; Ma, AD	1
BUZAS, A; OSOWIECKI, M; REGNIER, G	1
Bailly, C; Baldeyrou, B; Colson, P; Frappier, F; Kluza, J; Mambu, L; Rasoanaivo, P	1
Cheng, YY; Peng, MX; Wu, YJ	1
Bi, K; Dai, R; Li, K; Li, Q	1
Sun, SW; Tseng, HM	1
Brezová, V; Dvoranová, D; Kost'álová, D	1
Guo, M; Liu, S; Liu, Z; Wang, D	1
Baek, NI; Eom, DO; Eun, JS; Kim, DK; Kim, SH; Lee, KT; Lim, JP; Park, HW; Shin, TY; Yang, JH	1
Di, DL; Jiang, SX; Liu, YW; Ma, ZG	1
Li, ZH; Qin, HL; Wang, P; Yang, JR	1
Chen, XG; Guo, XK; Hu, ZD; Jia, L; Lin, SY; Wen, HG	1
Chen, SJ; Huang, XP; Ma, KS; Qin, SY; Zhong, GY	1
Li, CY; Lin, CH; Lu, HJ; Wu, TS	1
Dong, J; Hu, J; Tian, R; Wu, R; Xie, C; Zou, H	1
Liang, Y; Liu, XD; Lu, T; Song, J; Wang, GJ; Xie, L	1
Chen, LX; Hu, P; Liu, SM; Luo, GA; Wang, YM	1
Tang, YL; Wang, HQ; Zhao, DB	1
Hirakawa, K; Hirano, T; Kawanishi, S	1
Bilski, P; Chignell, CF; He, YY; Inbaraj, JJ; Kukielczak, BM; Sik, RH	1
Li, Y; Liu, Q; Liu, Y; Yao, S	1
Jin, J; Ma, JS; Sun, J; Wang, HS; Wen, QH; Zhang, HG; Zhou, QL	1
Islam, MM; Kumar, GS; Sinha, R	1
Sheng, YX; Sun, SQ; Xu, JT; Zhang, JL	1
Lei, P; Li, XZ; Liu, S	1
Liang, X; Ren, L; Xu, Q; Xue, X; Zhang, F	1
Ma, Y; Shi, R; Tan, B; Wang, T	1
Cui, M; Guo, X; Liu, S; Liu, Z; Song, F; Wang, Z	1
Bi, K; Deng, Y; Li, S; Liao, Q; Pan, B; Xie, Z	1
Bi, KS; Deng, YT; Jiang, XF; Liao, QF; Xie, ZY; Yao, MC	1
Bao, TD; Dong, Y; Li, YJ; Pan, GF; Weng, XG; Yang, Q; Zhang, YF; Zhu, XX	1
Dostál, J; Grycová, L; Hulová, D; Kares, R; Lemière, F; Maier, L; Marek, R; Necas, M; Standara, S	1
Bhadra, K; Kumar, GS; Maiti, M	1
Chowdhury, SR; Islam, MM; Kumar, GS	1
Feng, J; Jin, Y; Liang, X; Liu, Y; Xiao, Y; Xue, X; Zhang, J; Zhang, X	1
Du, M; Jin, R; Kang, C; Li, J; Li, M; Liu, S	1
Islam, MM; Suresh Kumar, G	1
Wu, DZ; Yu, X; Yuan, JY; Zhang, DG	1
Kumar, GS; Sinha, R	1
Chen, X; Duan, H; Hu, Y; Mu, X	1
Cardenas, LB; Ilag, LL; Maddalo, G; Shariatgorji, M; Spacil, Z	1
Chen, JH; Hu, FD; Huang, XY; Zhai, HL	1
Bhadra, K; Kumar, GS	2
Cheng, MC; Liu, YQ; Wang, LX; Xiao, HB	1
Fu, J; Guo, L; Pan, L; Zhu, H	1
Duan, C; Li, P; Lin, C; Liu, J; Ren, J	1
Che, CT; Chen, ML; Ip, SP; Tsai, SH; Xian, YF; Yang, JY	1
Inoue, M; Mizukami, H; Suzuki, H; Tanabe, H	1
Cai, F; Chen, W; Feng, J; Jiang, B; Tao, X; Wei, H; Xu, W	1
Cai, B; Fu, X; Li, J; Liu, X; Yin, D; Zhang, Y	1
Cai, L; Luo, W; Zhang, Q; Zhong, G	1
Huo, P; Xu, Y; Zeng, Y	1
Geng, Z; Luo, W; Qu, X; Zhang, Y; Zheng, H	1
Hasada, K; Mizukami, H; Nagatsu, A; Nishimura, T; Sugimoto, N; Yamazaki, T; Yoshida, T	1
Gao, C; Jiang, J; Qiu, F; Tan, Y; Zhang, X	1
Du, LM; Wu, H; Zhang, LB	1
Antonenko, YN; Chernyak, BV; Domnina, LV; Ivanova, OY; Korshunova, GA; Lyamzaev, KG; Pustovidko, AV; Roginsky, VA; Rokitskaya, TI; Severina, II; Simonyan, RA; Skulachev, MV; Skulachev, VP; Sumbatyan, NV; Tashlitsky, VN	1
Li, Z; Liu, F; Shi, X; Zhong, M	1
Chen, LQ; Ding, PL; Li, YG; Lu, Y	1
Cui, M; Liu, S; Wan, C; Xu, N; Yang, H	1
Mishra, S; Patel, MB	1
Chen, Y; Li, Y; Men, W; Wang, Y; Weng, X; Yang, Q; Zhu, X; Zou, L	1
Chen, Y; Dong, Y; Li, T; Li, Y; Wang, Y; Yang, Q; Yang, W; Zhang, Y; Zhu, X	1
Di, D; Jiang, S; Ma, Z; Wang, Q	1
Chen, Z; Liu, L	1
Feng, W; Kong, J; Wang, Z; Zhang, Q; Zhu, J	1
Chen, Y; Li, T; Li, Y; Wang, Y; Yang, Q; Yang, W; Zhang, D; Zhang, Y; Zhu, X	1
Ko, BS; Lee, HW; Lee, JH; Lee, MY; Lee, SH; Li, Y; Moon, DC; Park, JY; Ryuk, JA; Seo, CS; Son, JK; Zheng, MS	1
Fan, G; Lai, XR; Luo, WZ; Tang, C; Yue, QH; Zhang, MY; Zhang, Y; Zhou, XD	1
Li, J; Li, N; Ma, F; Wang, J; Wang, X; Wang, Y; Yao, Q; Yao, S; Zhang, L	1
Antonenko, YN; Chernyak, BV; Lyamzaev, KG; Pustovidko, AV; Rogov, AG; Rokitskaya, TI; Severina, II; Simonyan, RA; Skulachev, VP; Trendeleva, TA; Zvyagilskaya, RA	1
Hossain, M; Khan, AY; Kumar, GS	1
Antonenko, YN; Chernyak, BV; Domnina, LV; Dugina, VB; Galimov, ER; Ivanova, OY; Izyumov, DS; Lyamzaev, KG; Pustovidko, AV; Rogov, AG; Rokitskaya, TI; Severina, II; Shagieva, GS; Simonyan, RA; Skulachev, MV; Tashlitsky, VN; Titova, EV; Trendeleva, TA; Zvyagilskaya, RA	1
He, K; Li, X; Liu, X; Wang, D; Yang, Y; Ye, X; Yi, J	1
Huang, QW; Li, XF; Su, J; Wang, J; Zhang, YL	1
Dai, HF; Guo, ZK; Liu, SB; Mei, WL; Wang, QH; Wei, DJ; Yang, DL; Zeng, YB	1
An, R; Wang, XH; Xu, RC; Zhang, H; Zhang, YZ	1
He, F; Liu, M; Pan, L; Qian, Z; Tang, Y; Zhang, Q; Zhu, H	1
Chen, Y; Gong, ZP; Li, YJ; Men, W; Wang, YJ; Weng, XG; Yang, Q; Zhang, RJ; Zhu, XX	1
Chen, S; Couch, L; Dobrovolsky, VN; Guo, L; Li, Y; Lin, H; Mei, N; Wan, L	1
Chang, CY; Chang, YP; Lo, SN; Tsai, KC; Ueng, YF; Wu, TS	1
Li, J; Tan, S; Ye, H; Zhou, C	1
Kang, J; Zhang, Y	1
Jiao, Z; Li, ZD; Liu, QF; Shi, XJ; Wang, B; Zhong, MK	1
Chen, Y; Dong, Y; Gong, Z; Li, Y; Wang, Y; Weng, X; Yang, Q; Zhang, R; Zhu, X	1
Gerhardova, D; Havlikova, M; Ulrichova, J; Vrba, J	1
Li, BC; Li, JX; Wang, JY; Wang, RL; Xiao, XH; Yan, D; Zhang, LL	1
Cui, W; Han, Y; Hu, S; Luk, WW; Mak, S; Tsim, KW	1
Liu, JX; Ma, ZT; Yang, XW; Zhang, Y	1
Guo, L; Li, S; Liu, C; Ma, B; Qin, Y; Ren, J; Tang, Y; Wang, J; Wang, Y; Yang, X; Zhang, Y	1
Bian, B; Han, L; Li, Y; Ren, W; Si, N; Wang, H; Wei, X; Xin, S; Yang, J; Zhao, H; Zuo, R	1
Du, LM; Feng, JX; Fu, YL; Li, CF; Li, Y; Liu, HL	1
Cai, F; Hu, P; Li, Y; Wang, Y; Zhang, H; Zhang, M	1
Jadhav, AS; Reddy, V; Vijaya Anand, R	1
Bao, T; Chen, Z; Meng, J; Zhang, W	1
Kim, JH; Kim, OS; Seo, CS; Shin, HK	1
Bao, GL; Ji, QA; Liu, Y; Wei, Q; Xiao, CW	1
Bai, M; Jiang, H; Li, L; Song, F; Sun, S; Weng, Y; Zeng, S; Zhou, H; Zhou, S	1
Alolga, RN; Chen, Y; Fan, Y; Lelu Kakila, J; Li, J; Li, P; Qi, LW; Zhang, G; Zhao, YJ	1
Guo, X; Jiang, Y; Ma, X; Tu, P; Wang, W; Zhao, M	1
Seo, CS; Shin, HK	1
Huang, CY; Huang, ZY; Liu, DD; Pan, BB; Ye, YL; Yu, YP; Zhang, Q	1
Fukuda, M; Hosoe, T; Ishikawa, K; Sato, F; Takeda, H; Wakana, D	1
Grzybek, M; Jaworska, A; Kukula-Koch, W; Paleolog, J; Phiri, AM; Strachecka, A; Tomczuk, K	1
Chatterjee, S; Suresh Kumar, G	1
Sun, X; Wang, J; Wang, Y; Zhang, C; Zheng, D	1
Cong, H; Deng, S; Huo, X; Sun, C; Wang, C; Wang, Y; Wu, B; Xiang, T; Zhang, B; Zhang, H; Zhang, L; Zhao, X; Zheng, L	1
Chen, G; Dou, D; Guo, S; Xu, Y; Zhang, M; Zhang, X	1
Gao, YG; He, ZM; Li, GF; Yang, H; Zhang, LX; Zhao, Y; Zheng, JY; Zhu, HY	1
Chen, YS; Huang, CC; Lee, IJ; Li, LA; Lo, SN; Ueng, YF; Wang, CW; Wu, TS	1
Jiang, Y; Li, HJ; Li, P; Lu, J; Ni, H; Wu, TJ	1
Jin, T; Li, C; Ma, J; Meng, J; Tian, J; Yang, L; Zhao, R	1
Bianco, A; Cacchione, S; Cianni, L; Franceschin, M; Frezza, C; Gu, L; Hu, MH; Huang, Z; Micheli, E; Pitorri, M; Serafini, M; Su, H	1
Nakamura, S; Nihashi, Y; Shinji, S; Takaya, T; Umezawa, K	1
Kamimura, S; Nishihara, M; Osumi, Y; Shiota, H	1
Hosoe, T; Takeda, H; Wakana, D; Yoshida, H	1
Hosoe, T; Sato, F; Takeda, H; Wakana, D; Yoshida, H	1
Amenitsch, H; Bianchi, F; Comez, L; D'Amico, F; Gessini, A; Libera, V; Longo, M; Masciovecchio, C; Paciaroni, A; Petrillo, C; Rossi, B; Sacchetti, F; Sebastiani, F; Sissi, C	1
Banono, NS; Ent, WV; Esguerra, CV; Gawel, K; Kukula-Koch, W; Nieoczym, D; Stepnik, K; Tarabasz, D; Turski, WA	1
Chen, J; Chen, YJ; Cui, GZ; Hu, SQ; Ma, M; Sun, KH; Tao, C; Wu, ZZ	1
Cheng, J; Feng, J; Feng, S; Ma, C; Song, W; Wang, R; Xie, L; Zhang, X; Zhao, W	1
Fan, H; Hou, Z; Jin, Y; Li, Q; Li, Y; Xiao, C; Zhang, Y	1
Ge, P; Guo, R; Guo, S; Lei, S; Qi, Y; Wang, N; Wei, X; Wu, W; Xiao, Q; Yang, N; Zhang, Q; Zhao, L; Zhao, X; Zhou, P; Zhu, H	1

Reviews

3 review(s) available for berberine and palmatine

Article	Year
Annual review of LSD1/KDM1A inhibitors in 2020. European journal of medicinal chemistry, 2021, Mar-15, Volume: 214 Topics: Antineoplastic Agents, Phytogenic; Enzyme Inhibitors; Histone Demethylases; Humans; Molecular Structure; Neoplasms	2021
Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: binding aspects and implications for drug design. Medicinal research reviews, 2011, Volume: 31, Issue:6 Topics: Alkaloids; Animals; Benzophenanthridines; Berberine; Berberine Alkaloids; Calorimetry; Chemistry, Pharmaceutical; DNA; Drug Design; Humans; Isoquinolines; Mice; Models, Chemical; Nucleic Acids; RNA; Spectrophotometry; Temperature	2011
Novel mitochondria-targeted compounds composed of natural constituents: conjugates of plant alkaloids berberine and palmatine with plastoquinone. Biochemistry. Biokhimiia, 2012, Volume: 77, Issue:9 Topics: Antineoplastic Agents; Antioxidants; Berberine; Berberine Alkaloids; Humans; Mitochondria; Plastoquinone	2012

Other Studies

163 other study(ies) available for berberine and palmatine

Article	Year
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061 Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites	2011
Neuraminidase inhibitory activities of quaternary isoquinoline alkaloids from Corydalis turtschaninovii rhizome. Bioorganic & medicinal chemistry, 2014, Nov-01, Volume: 22, Issue:21 Topics: Alkaloids; Anti-Bacterial Agents; Clostridium Infections; Clostridium perfringens; Corydalis; Enzyme Inhibitors; Humans; Isoquinolines; Molecular Docking Simulation; Neuraminidase; Rhizome	2014
Isoquinoline alkaloids from Coptis japonica stimulate the myoblast differentiation via p38 MAP-kinase and Akt signaling pathway. Bioorganic & medicinal chemistry letters, 2017, 03-15, Volume: 27, Issue:6 Topics: Alkaloids; Animals; Cell Differentiation; Cell Line; Coptis; Mice; Myoblasts	2017
PAIN-less identification and evaluation of small molecule inhibitors against protein tyrosine phosphatase 1B. MedChemComm, 2017, Jun-01, Volume: 8, Issue:6 Topics:	2017
Isoquinoline Alkaloids from Berberis vulgaris as Potential Lead Compounds for the Treatment of Alzheimer's Disease. Journal of natural products, 2019, 02-22, Volume: 82, Issue:2 Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Berberis; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Isoquinolines; Magnetic Resonance Spectroscopy; Plant Exudates	2019
Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3-Kinase/Akt Phosphorylation. Journal of medicinal chemistry, 2022, 05-26, Volume: 65, Issue:10 Topics: Adenosine Diphosphate; Animals; Berberine Alkaloids; Blood Platelets; Cell Adhesion Molecules; Cyclic GMP-Dependent Protein Kinases; Mice; Microfilament Proteins; Phosphatidylinositol 3-Kinase; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt	2022
[Chemical constituents of Asteropyrum peltatum (Franch.) Drumm. et Hutch]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1990, Volume: 15, Issue:12 Topics: Berberine; Berberine Alkaloids; Drugs, Chinese Herbal	1990
[Quantitative determination of 5 alkaloids in plants of Coptis from China]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1989, Volume: 14, Issue:2 Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, Thin Layer; Densitometry; Drugs, Chinese Herbal; Triterpenes	1989
[Determination of berberine and palmatine in cortex phellodendron and Chinese patent medicines by HPLC]. Yao xue xue bao = Acta pharmaceutica Sinica, 1989, Volume: 24, Issue:4 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal	1989
Protoberberine alkaloids as antimalarials. Journal of medicinal chemistry, 1988, Volume: 31, Issue:6 Topics: Animals; Antimalarials; Berberine; Berberine Alkaloids; Plasmodium falciparum	1988
Natural protoberberine alkaloids from Enantia chlorantha, palmatine, columbamine and jatrorrhizine for thioacetamide-traumatized rat liver. Acta anatomica, 1988, Volume: 131, Issue:2 Topics: Acetamides; Animals; Berberine; Berberine Alkaloids; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Liver; Male; Plants; Rats; Rats, Inbred Strains; Thioacetamide	1988
[Analysis of berberine-type alkaloids in rhizoma Coptidis and Chinese patent medicines by micellar chromatography]. Yao xue xue bao = Acta pharmaceutica Sinica, 1986, Volume: 21, Issue:6 Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, Liquid; Medicine, Chinese Traditional; Plant Extracts; Plants, Medicinal	1986
Simultaneous determination of berberine, palmatine and coptisine in crude drugs and oriental pharmaceutical preparations by ion-pair high-performance liquid chromatography. Chemical & pharmaceutical bulletin, 1982, Volume: 30, Issue:1 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Medicine, East Asian Traditional	1982
[Study on baths with crude drug. II.: the effects of coptidis rhizoma extracts as skin permeation enhancer]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1995, Volume: 115, Issue:8 Topics: Animals; Baths; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Fluorouracil; In Vitro Techniques; Male; Rats; Rats, Wistar; Skin Absorption; Solubility; Stimulation, Chemical; Water	1995
Berberine complexes with DNA in the berberine-induced apoptosis in human leukemic HL-60 cells. Cancer letters, 1995, Jul-13, Volume: 93, Issue:2 Topics: Apoptosis; Berberine; Berberine Alkaloids; DNA, Neoplasm; G1 Phase; Humans; Leukemia, Promyelocytic, Acute; S Phase; Tumor Cells, Cultured	1995
Determination of trace impurities of peptides and alkaloids by capillary electrophoresis-ion spray mass spectrometry. Journal of chromatography. A, 1994, Sep-09, Volume: 679, Issue:1 Topics: Alkaloids; Amino Acid Sequence; Berberine; Berberine Alkaloids; Bradykinin; Drug Contamination; Electrophoresis; Kallidin; Mass Spectrometry; Molecular Sequence Data; Oligopeptides; Spectrophotometry, Ultraviolet	1994
[Thin layer chromatographic fingerprint of Rhizomata of Coptis spp]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1993, Volume: 18, Issue:6 Topics: Berberine; Berberine Alkaloids; Chromatography, Thin Layer; Drugs, Chinese Herbal; Species Specificity	1993
Determination of gentiopicroside, mangiferin, palmatine, berberine, baicalin, wogonin and glycyrrhizin in the traditional Chinese medicinal preparation sann-joong-kuey-jian-tang by high-performance liquid chromatography. Journal of chromatography. A, 1996, Apr-12, Volume: 730, Issue:1-2 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Iridoid Glucosides; Iridoids; Pyrans; Reproducibility of Results; Xanthenes; Xanthones	1996
Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores. Phytochemistry, 1997, Volume: 44, Issue:2 Topics: Acetylcholinesterase; Alkaloids; Animals; Anti-Bacterial Agents; Benzophenanthridines; Berberine; Berberine Alkaloids; Brain; Butyrylcholinesterase; Cell Membrane; Choline O-Acetyltransferase; Cholinesterase Inhibitors; DNA Polymerase I; Enzyme Inhibitors; Erythrocytes; Hemolysis; Isoquinolines; Kinetics; Radioligand Assay; Receptors, Adrenergic; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Serotonin; Reverse Transcriptase Inhibitors; Swine	1997
Antimicrobial activity of some 13-alkyl substituted protoberberinium salts. Planta medica, 1997, Volume: 63, Issue:3 Topics: Berberine; Berberine Alkaloids; Microbial Sensitivity Tests; Staphylococcus aureus; Structure-Activity Relationship	1997
[Callus induction of Coptis species and generation of alkaloids]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1996, Volume: 21, Issue:8 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Techniques; Magnoliopsida	1996
Differential inhibitory effects of protoberberines on sterol and chitin biosyntheses in Candida albicans. The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:5 Topics: Amphotericin B; Antifungal Agents; Berberine; Berberine Alkaloids; Candida; Candida albicans; Cell Membrane; Cell Wall; Chitin; Chitin Synthase; Ergosterol; Methyltransferases; Miconazole; Microbial Sensitivity Tests; Plant Extracts; Plants, Medicinal; Sterols	1999
Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, berberine, coptisine, palmatine, jateorrhizine and glycyrrhizin in Kampo medicines by ion-pair high-performance liquid chromatography. Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:10 Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Glycyrrhizic Acid; Medicine, Kampo	1999
Growth-inhibiting effects of Coptis japonica root-derived isoquinoline alkaloids on human intestinal bacteria. Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:3 Topics: Alkaloids; Bacteria; Berberine; Berberine Alkaloids; Humans; Intestinal Mucosa; Isoquinolines; Plant Extracts; Plant Roots	1999
Analysis of coptisine, berberine and palmatine in adulterated Chinese medicine by capillary electrophoresis-electrospray ion trap mass spectrometry. Journal of chromatography. A, 2000, Jan-14, Volume: 866, Issue:2 Topics: Berberine; Berberine Alkaloids; Drug Contamination; Electrophoresis, Capillary; Mass Spectrometry; Medicine, Chinese Traditional; Spectrophotometry, Ultraviolet	2000
Narrowbore high performance liquid chromatography of berberine and palmatine in crude drugs and pharmaceuticals with ion-pair extraction using cobalt thiocyanate reagent. Journal of pharmaceutical and biomedical analysis, 1999, Volume: 21, Issue:1 Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Cobalt; Indicators and Reagents; Medicine, Chinese Traditional; Thiocyanates	1999
Inhibition of dopamine biosynthesis by protoberberine alkaloids in PC12 cells. Neurochemical research, 2000, Volume: 25, Issue:3 Topics: Animals; Berberine; Berberine Alkaloids; Calcium; Dopamine; Dopamine Antagonists; PC12 Cells; Rats; Tyrosine 3-Monooxygenase	2000
Antifeeding activity of isoquinoline alkaloids identified in Coptis japonica roots against Hyphantria cunea (Lepidoptera: Arctiidae) and Agelastica coerulea (Coleoptera: Galerucinae). Journal of economic entomology, 2000, Volume: 93, Issue:2 Topics: Animals; Berberine; Berberine Alkaloids; Coleoptera; Feeding Behavior; Isoquinolines; Molecular Structure; Moths; Plant Roots; Plants, Medicinal	2000
Coptidis rhizoma inhibits growth and proteases of oral bacteria. Oral diseases, 2000, Volume: 6, Issue:5 Topics: Actinomyces; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents; Bacteria; Berberine; Berberine Alkaloids; Coptis chinensis; Drugs, Chinese Herbal; Humans; Lactobacillus; Lethal Dose 50; Matrix Metalloproteinase Inhibitors; Microbial Sensitivity Tests; Mouth; Prevotella intermedia; Prevotella nigrescens; Protease Inhibitors; Ranunculaceae; Streptococcus	2000
In vitro cytotoxicity of the protoberberine-type alkaloids. Journal of natural products, 2001, Volume: 64, Issue:7 Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Berberine Alkaloids; Brain Neoplasms; Breast Neoplasms; Colonic Neoplasms; Crystallography, X-Ray; Databases, Factual; Doxorubicin; Female; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Mitomycin; Molecular Structure; Ovarian Neoplasms; Papaver; Plants, Medicinal; Stomach Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured	2001
[Study on the quality standards for xianghe suppository]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2001, Volume: 24, Issue:9 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drugs, Chinese Herbal; Quality Control; Suppositories	2001
Inhibition of type A monoamine oxidase by coptisine in mouse brain. Life sciences, 2001, Dec-28, Volume: 70, Issue:6 Topics: Animals; Berberine; Berberine Alkaloids; Binding, Competitive; Brain; Clorgyline; Dialysis; Dose-Response Relationship, Drug; Iproniazid; Kynuramine; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship	2001
Transfer of cationic antibacterial agents berberine, palmatine, and benzalkonium through bimolecular planar phospholipid film and Staphylococcus aureus membrane. IUBMB life, 2001, Volume: 52, Issue:6 Topics: Anti-Infective Agents, Local; Bacterial Proteins; Benzalkonium Compounds; Berberine; Berberine Alkaloids; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cations; Dose-Response Relationship, Drug; Membrane Potentials; Models, Chemical; Multidrug Resistance-Associated Proteins; Mutation; Phospholipids; Staphylococcus aureus; Time Factors	2001
[Determination of alkaloids in Coptis-Cinnamomum compatibility by capillary electrophoresis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1999, Volume: 24, Issue:5 Topics: Alkaloids; Berberine; Berberine Alkaloids; Cinnamomum; Coptis; Drug Combinations; Drugs, Chinese Herbal; Electrophoresis, Capillary; Plants, Medicinal	1999
Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by a Coptidis Rhizoma extract and protoberberine alkaloids. Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:11 Topics: Animals; Berberine; Berberine Alkaloids; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Coptis chinensis; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme Activation; Nerve Growth Factors; Neurites; PC12 Cells; Rats	2002
[Studies on separation and identification of Rhizoma coptidis brugs based on microemulsion thin-layer chromatography]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2000, Volume: 25, Issue:5 Topics: Berberine; Berberine Alkaloids; Chromatography, Thin Layer; Coptis chinensis; Drug Combinations; Drugs, Chinese Herbal; Plants, Medicinal; Ranunculaceae	2000
[Studies on alkaloids of Asteropyrum cavaleriei (Lévl. et Vant.) Drumm. et Hutch]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2000, Volume: 25, Issue:8 Topics: Alkaloids; Aporphines; Berberine; Berberine Alkaloids; Plants, Medicinal; Ranunculaceae	2000
A simple method for fabrication of silver-coated sheathless electrospray emitters. Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:5 Topics: Animals; Berberine; Berberine Alkaloids; Electrophoresis, Capillary; Myoglobin; Silver; Spectrometry, Mass, Electrospray Ionization	2003
[Determination of alkaloids from Coptis chinensis Franch. and Phellodendron amurense Rupr. Decocted together in baitouweng decocta by high performance capillary electrophoresis]. Se pu = Chinese journal of chromatography, 2002, Volume: 20, Issue:6 Topics: Alkaloids; Berberine; Berberine Alkaloids; Coptis; Drug Combinations; Drugs, Chinese Herbal; Electrophoresis, Capillary; Phellodendron; Solubility	2002
Palmatine and berberine isolation artifacts. Journal of natural products, 2003, Volume: 66, Issue:4 Topics: Alkaloids; Berberine; Berberine Alkaloids; Berberis; Crystallography, X-Ray; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Structure-Activity Relationship	2003
[The changes of some chemical components in banxiaxiexintang decoction of different combinations]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2002, Volume: 27, Issue:5 Topics: Berberine; Berberine Alkaloids; Drug Combinations; Drugs, Chinese Herbal; Glycyrrhizic Acid; Plant Extracts; Plants, Medicinal	2002
High-performance capillary electrophoresis for determining the contents of berberine, jatrorrhizine and palmatine in Gegenqinlian decoction. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:7 Topics: Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Electrophoresis, Capillary; Medicine, Chinese Traditional	2003
[A berberine alkaloid isolated from Enantia polycarpa (Anonacea) cortex; palmatine]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1959, Mar-02, Volume: 248, Issue:9 Topics: Alkaloids; Animals; Berberine; Berberine Alkaloids; Humans; Urochordata	1959
Cytotoxicity and DNA binding properties of the plant alkaloid burasaine. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2003, Volume: 20, Issue:4-5 Topics: Algorithms; Antineoplastic Agents, Phytogenic; Berberine; Cell Cycle; Cell Survival; DNA Topoisomerases; DNA, Neoplasm; HL-60 Cells; Humans; Plasmids; Spectrophotometry, Atomic; Temperature	2003
[Study on the solubility changes of Rhizoma Coptidis' main chemical constituents influenced by the proportion of Rhizoma Coptidis and Fructus Evodiae]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:7 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drug Combinations; Drugs, Chinese Herbal; Evodia; Plant Roots; Plants, Medicinal; Solubility	2003
Determination of mangiferin, jateorrhizine, palmatine, berberine, cinnamic acid, and cinnamaldehyde in the traditional Chinese medicinal preparation Zi-Shen pill by high-performance liquid chromatography. Journal of chromatographic science, 2004, Volume: 42, Issue:4 Topics: Acrolein; Berberine; Berberine Alkaloids; Calibration; Chromatography, High Pressure Liquid; Cinnamates; Drugs, Chinese Herbal; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Xanthones	2004
Improved detection of Coptidis alkaloids by field-amplified sample stacking in capillary electrophoresis. Journal of pharmaceutical and biomedical analysis, 2004, Sep-21, Volume: 36, Issue:1 Topics: Alkaloids; Berberine; Berberine Alkaloids; Coptis; Coptis chinensis; Drugs, Chinese Herbal; Electrophoresis, Capillary; Reference Standards; Reproducibility of Results; Rhizome; Sensitivity and Specificity	2004
Oxygen activation by photoexcited protoberberinium alkaloids from Mahonia aquifolium. Phytotherapy research : PTR, 2004, Volume: 18, Issue:8 Topics: Berberine; Berberine Alkaloids; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Mahonia; Photochemistry; Photosensitizing Agents; Phytotherapy; Plant Extracts	2004
Structural elucidation and identification of alkaloids in Rhizoma Coptidis by electrospray ionization tandem mass spectrometry. Journal of mass spectrometry : JMS, 2004, Volume: 39, Issue:11 Topics: Berberine; Berberine Alkaloids; Coptis; Drugs, Chinese Herbal; Plant Roots; Spectrometry, Mass, Electrospray Ionization	2004
Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa. Archives of pharmacal research, 2004, Volume: 27, Issue:11 Topics: Acetylcholinesterase; Animals; Benzophenanthridines; Berberine; Berberine Alkaloids; Cholinesterase Inhibitors; Corydalis; Dose-Response Relationship, Drug; Kinetics; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Plant Extracts; Plant Leaves; Plant Stems	2004
[Determination of four alkaloids in Berberis plants by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:12 Topics: Alkaloids; Benzylisoquinolines; Berberine; Berberine Alkaloids; Berberis; China; Chromatography, High Pressure Liquid; Ecosystem; Plant Bark; Plant Roots; Plant Stems; Plants, Medicinal; Species Specificity	2003
[Establishment of the control substance of plant drug and fingerprints of Coptis chinensis]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2004, Volume: 26, Issue:6 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Magnetic Resonance Spectroscopy; Plants, Medicinal; Quality Control	2004
Analysis of protoberberine alkaloids in several herbal drugs and related medicinal preparations by non-aqueous capillary electrophoresis. Journal of separation science, 2005, Volume: 28, Issue:1 Topics: Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Electrophoresis, Capillary; Plants, Medicinal; Reproducibility of Results	2005
[Quality assessment of Coptis chinensis in China]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:7 Topics: Alkaloids; Berberine; Berberine Alkaloids; China; Chromatography, High Pressure Liquid; Coptis; Ecosystem; Plants, Medicinal; Quality Control; Spectrophotometry, Ultraviolet	2005
A rapid and simple determination of protoberberine alkaloids in cortex phellodendri by 1H NMR and its application for quality control of commercial traditional Chinese medicine prescriptions. Journal of pharmaceutical and biomedical analysis, 2006, Jan-23, Volume: 40, Issue:1 Topics: Alkaloids; Berberine; Berberine Alkaloids; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Models, Chemical; Quality Control; Reproducibility of Results	2006
Capillary electrochromatography with a neutral monolithic column for classification of analytes and determination of basic drugs in human serum. Electrophoresis, 2005, Volume: 26, Issue:18 Topics: Atenolol; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Humans; Methacrylates; Metoprolol; Reproducibility of Results; Sensitivity and Specificity; Silanes	2005
Simultaneous determination of berberine and palmatine in rat plasma by HPLC-ESI-MS after oral administration of traditional Chinese medicinal preparation Huang-Lian-Jie-Du decoction and the pharmacokinetic application of the method. Journal of pharmaceutical and biomedical analysis, 2006, Mar-18, Volume: 40, Issue:5 Topics: Animals; Area Under Curve; Berberine; Berberine Alkaloids; Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Half-Life; Indicators and Reagents; Male; Quality Control; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Solutions; Spectrometry, Mass, Electrospray Ionization	2006
[HPLC fingerprint for the Corydalis saxicola Bunting injection]. Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:9 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Corydalis; Drugs, Chinese Herbal; Injections; Plants, Medicinal; Quality Control; Spectrometry, Mass, Electrospray Ionization	2005
[Studies on the alkaloids from herb of Corydalis adunca]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:22 Topics: Berberine; Berberine Alkaloids; Corydalis; Plants, Medicinal	2005
The mechanism of guanine specific photooxidation in the presence of berberine and palmatine: activation of photosensitized singlet oxygen generation through DNA-binding interaction. Chemical research in toxicology, 2005, Volume: 18, Issue:10 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; DNA Damage; Guanine; Humans; Models, Chemical; Oxidation-Reduction; Photosensitizing Agents; Singlet Oxygen; Spectrometry, Fluorescence	2005
Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.). 2. Palmatine, hydrastine, canadine, and hydrastinine. Chemical research in toxicology, 2006, Volume: 19, Issue:6 Topics: Alkaloids; Benzylisoquinolines; Berberine; Berberine Alkaloids; Cell Line; Cell Survival; Humans; Hydrastis; Molecular Structure; Oxygen; Photochemistry; Photosensitizing Agents; Spectrum Analysis; Tetrahydroisoquinolines	2006
Nonaqueous capillary electrophoresis coupled with laser-induced native fluorescence detection for the analysis of berberine, palmatine, and jatrorrhizine in Chinese herbal medicines. Journal of separation science, 2006, Volume: 29, Issue:9 Topics: Acetates; Acetic Acid; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Electrophoresis, Capillary; Lasers; Medicine, Chinese Traditional; Molecular Structure; Plant Extracts; Plants, Medicinal; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence	2006
[Qualitative and quantitative determination of the main components of huanglianjiedu decoction by HPLC-UV/MS]. Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:4 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Gardenia; Mass Spectrometry; Phellodendron; Plants, Medicinal; Quality Control; Scutellaria baicalensis; Spectrophotometry, Ultraviolet	2006
RNA binding small molecules: studies on t-RNA binding by cytotoxic plant alkaloids berberine, palmatine and the comparison to ethidium. Biophysical chemistry, 2007, Volume: 125, Issue:2-3 Topics: Alkaloids; Berberine; Berberine Alkaloids; Ethidium; Intercalating Agents; Nucleic Acid Conformation; Plants; RNA, Transfer; RNA, Transfer, Phe; Salts; Spectrum Analysis; Thermodynamics	2007
[Quality analysis and evaluation of Rhizoma Coptidis under different cultivation conditions]. Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:10 Topics: Berberine; Berberine Alkaloids; China; Chromatography, High Pressure Liquid; Coptis; Ecosystem; Plants, Medicinal; Quality Control; Reference Standards; Reproducibility of Results; Rhizome; Spectrometry, Mass, Electrospray Ionization	2006
[Determination of 3 kinds of components in huanglian jiedu decoction by HPLC under different UV wavelengths]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:20 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Flavonoids; Iridoids; Plants, Medicinal; Pyrans; Quality Control; Ultraviolet Rays	2006
High performance liquid chromatography-mass spectrometry analysis of protoberberine alkaloids in medicine herbs. Journal of separation science, 2007, Volume: 30, Issue:6 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis chinensis; Drugs, Chinese Herbal; Mass Spectrometry; Molecular Structure; Phellodendron	2007
Simultaneous quantification of three alkaloids of Coptidis Rhizoma in rat urine by high-performance liquid chromatography: application to pharmacokinetic study. Biopharmaceutics & drug disposition, 2007, Volume: 28, Issue:9 Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Female; Male; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Rhizome	2007
Studies on alkaloids binding to GC-rich human survivin promoter DNA using positive and negative ion electrospray ionization mass spectrometry. Journal of mass spectrometry : JMS, 2008, Volume: 43, Issue:3 Topics: Alkaloids; Antineoplastic Agents; Base Composition; Benzylisoquinolines; Berberine; Berberine Alkaloids; DNA; GC Rich Sequence; Humans; Inhibitor of Apoptosis Proteins; Intercalating Agents; Microtubule-Associated Proteins; Molecular Structure; Neoplasm Proteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Reserpine; Spectrometry, Mass, Electrospray Ionization; Survivin; Tandem Mass Spectrometry	2008
Simultaneous determination of berberine, palmatine and jatrorrhizine by liquid chromatography-tandem mass spectrometry in rat plasma and its application in a pharmacokinetic study after oral administration of coptis-evodia herb couple. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Mar-01, Volume: 863, Issue:2 Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Evodia; Male; Molecular Structure; Plant Preparations; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2008
[Analysis of the main components of coptis-evodia herb couple by HPLC-DAD-MS]. Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:3 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Evodia; Plant Extracts; Spectrometry, Mass, Electrospray Ionization	2008
[Absorption of extractive Rhizoma Coptidis in rat everted gut scas]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:9 Topics: Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Cicatrix; Colon; Drugs, Chinese Herbal; Gastrointestinal Tract; Ileum; Jejunum; Male; Rats; Rats, Wistar	2008
Covalent bonding of azoles to quaternary protoberberine alkaloids. Magnetic resonance in chemistry : MRC, 2008, Volume: 46, Issue:12 Topics: Alkaloids; Azoles; Berberine; Berberine Alkaloids; Chemistry, Organic; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Mass Spectrometry	2008
DNA-binding cytotoxic alkaloids: comparative study of the energetics of binding of berberine, palmatine, and coralyne. DNA and cell biology, 2008, Volume: 27, Issue:12 Topics: Alkaloids; Animals; Berberine; Berberine Alkaloids; Calorimetry; Cytotoxins; DNA; Energy Metabolism; Male; Models, Biological; Nucleic Acid Denaturation; Osmolar Concentration; Temperature	2008
Spectroscopic and calorimetric studies on the binding of alkaloids berberine, palmatine and coralyne to double stranded RNA polynucleotides. The journal of physical chemistry. B, 2009, Jan-29, Volume: 113, Issue:4 Topics: Alkaloids; Base Pairing; Berberine; Berberine Alkaloids; Binding Sites; Calorimetry; Kinetics; Models, Molecular; Polyribonucleotides; RNA, Double-Stranded; Spectrophotometry; Thermodynamics	2009
Purification of alkaloids from Corydalis yanhusuo W. T. Wang using preparative 2-D HPLC. Journal of separation science, 2009, Volume: 32, Issue:9 Topics: 1-Butanol; Acetates; Acetonitriles; Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Corydalis; Mass Spectrometry	2009
[Study on vitro release and transdermal behaviors of Yulian cataplasm]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:8 Topics: Animals; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Indole Alkaloids; Mice; Plant Extracts; Quinazolines; Skin; Skin Absorption	2009
RNA-binding potential of protoberberine alkaloids: spectroscopic and calorimetric studies on the binding of berberine, palmatine, and coralyne to protonated RNA structures. DNA and cell biology, 2009, Volume: 28, Issue:12 Topics: Berberine; Berberine Alkaloids; Biological Products; Calorimetry; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Poly I-C; Protons; RNA; Spectrum Analysis; Thermodynamics	2009
[Effects of extracts and active components of Rhizoma Coptidis on contraction of circular smooth muscle isolated from guinea pig gastric antrum]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2009, Volume: 7, Issue:9 Topics: Animals; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Guinea Pigs; Muscle, Smooth; Plant Extracts; Pyloric Antrum	2009
Interaction of isoquinoline alkaloids with an RNA triplex: structural and thermodynamic studies of berberine, palmatine, and coralyne binding to poly(U).poly(A)()poly(U). The journal of physical chemistry. B, 2009, Oct-08, Volume: 113, Issue:40* Topics: Berberine; Berberine Alkaloids; Isoquinolines; Molecular Structure; Nucleic Acid Conformation; Polyribonucleotides; RNA; Thermodynamics	2009
Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells. Immunopharmacology and immunotoxicology, 2009, Volume: 31, Issue:4 Topics: Animals; Berberine; Berberine Alkaloids; Cells, Cultured; Drugs, Chinese Herbal; E-Selectin; Endothelium, Vascular; Esculin; Furans; Interleukin-6; Interleukin-8; Intestinal Mucosa; Lipopolysaccharides; Rats; Thromboxane B2; Umbelliferones	2009
Matrix-free thin-layer chromatography/laser desorption ionization mass spectrometry for facile separation and identification of medicinal alkaloids. Rapid communications in mass spectrometry : RCM, 2009, Volume: 23, Issue:23 Topics: Berberine; Berberine Alkaloids; Berberis; Chromatography, Thin Layer; Plant Extracts; Plant Roots; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2009
The application of digital image recognition to the analysis of two-dimensional fingerprints. Analytica chimica acta, 2010, Jan-11, Volume: 657, Issue:2 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Cluster Analysis; Drugs, Chinese Herbal; Signal Processing, Computer-Assisted	2010
Rhizoma coptidis and berberine-induced activation of murine microglia N9 cells. Journal of ethnopharmacology, 2010, May-04, Volume: 129, Issue:1 Topics: Animals; Berberine; Berberine Alkaloids; Calcium; Coptis; DNA, Complementary; Dose-Response Relationship, Drug; Enzymes; Flow Cytometry; Gene Expression; Gene Expression Regulation; Genes; Membrane Potential, Mitochondrial; Mice; Microglia; Phagocytosis; Plant Extracts; Reactive Oxygen Species; Rhizome; Up-Regulation	2010
[Preliminary study to investigate dynamic extract process of Huanglian Jiedu Tang and the mechanism of subsidence produce]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:1 Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavones; Flavonoids; Fractional Precipitation; Iridoids; Plants, Medicinal	2010
[Effects of four components of Rhizoma Corydalis on anoxia and peroxidation injuries in neonatal cardiomyocytes]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:1 Topics: Alkaloids; Animals; Animals, Newborn; Berberine; Berberine Alkaloids; Cell Hypoxia; Cells, Cultured; Hydrogen Peroxide; Myocytes, Cardiac; Rats	2010
Chemical and biological differentiation of Cortex Phellodendri Chinensis and Cortex Phellodendri Amurensis. Planta medica, 2010, Volume: 76, Issue:14 Topics: Animals; Anti-Bacterial Agents; Antidiarrheals; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Escherichia coli; Female; Gastrointestinal Motility; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Phellodendron; Pseudomonas aeruginosa	2010
Selective regulation of multidrug resistance protein in vascular smooth muscle cells by the isoquinoline alkaloid coptisine. Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:4 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Berberine Alkaloids; Cardiovascular Agents; Cell Line; Cell Line, Tumor; Coptis; Dactinomycin; Drug Resistance, Multiple; Gene Expression Regulation; Genes, MDR; Humans; Membrane Transport Proteins; Mice; Molecular Structure; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rhodamines; RNA, Messenger; Up-Regulation	2010
Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese Journal of pharmaceutical and biomedical analysis, 2010, Nov-02, Volume: 53, Issue:3 Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Chromatography, Liquid; Coptis; Flavanones; Flavonoids; Male; Medicine, Chinese Traditional; Rats; Rats, Sprague-Dawley; Scutellaria; Tandem Mass Spectrometry	2010
[Simultaneous determination of the five alkaloids in Rhizoma Coptidis by nonaqueous capillary electrophoresis]. Se pu = Chinese journal of chromatography, 2010, Volume: 28, Issue:4 Topics: Alkaloids; Berberine; Berberine Alkaloids; Coptis chinensis; Drugs, Chinese Herbal; Electrophoresis, Capillary	2010
[Simultaneous determination of jatrorrhizine, palmatine, berberine, and obacunone in Phellodendri Amurensis Cortex by RP-HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:16 Topics: Benzoxepins; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Limonins; Phellodendron	2010
[Simultaneous determination of berberine, palmatine, matrine, catechin and baicalin in Funing Shuan by micellar electrokinetic capillary chromatography-electrospray ionization mass spectrometry]. Se pu = Chinese journal of chromatography, 2010, Volume: 28, Issue:7 Topics: Alkaloids; Berberine; Berberine Alkaloids; Capillary Electrochromatography; Catechin; Drug Combinations; Drugs, Chinese Herbal; Flavonoids; Humans; Matrines; Quinolizines; Spectrometry, Mass, Electrospray Ionization	2010
[Simultaneous determination of six alkaloids in Coptis chinensis of different regions by RP-HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:19 Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal	2010
Application of 1H-NMR spectroscopy to validation of berberine alkaloid reagents and to chemical evaluation of Coptidis Rhizoma. Journal of natural medicines, 2011, Volume: 65, Issue:2 Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Extracts	2011
Interaction of berberine, palmatine, coralyne, and sanguinarine to quadruplex DNA: a comparative spectroscopic and calorimetric study. Biochimica et biophysica acta, 2011, Volume: 1810, Issue:4 Topics: Benzophenanthridines; Berberine; Berberine Alkaloids; Binding Sites; Calorimetry, Differential Scanning; Circular Dichroism; Ethidium; G-Quadruplexes; Humans; Isoquinolines; Spectrum Analysis; Thermodynamics	2011
Intestinal absorption mechanisms of berberine, palmatine, jateorhizine, and coptisine: involvement of P-glycoprotein. Xenobiotica; the fate of foreign compounds in biological systems, 2011, Volume: 41, Issue:4 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Berberine Alkaloids; Biological Transport; Caco-2 Cells; Cyclosporine; Drugs, Chinese Herbal; Humans; Intestinal Absorption; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Propionates; Quinolines; Verapamil	2011
Ionic liquid sensitized fluorescence determination of four isoquinoline alkaloids. Talanta, 2011, Jul-15, Volume: 85, Issue:1 Topics: Alkaloids; Berberine; Berberine Alkaloids; Ionic Liquids; Isoquinolines; Temperature	2011
Novel mitochondria-targeted antioxidants: plastoquinone conjugated with cationic plant alkaloids berberine and palmatine. Pharmaceutical research, 2011, Volume: 28, Issue:11 Topics: Antioxidants; Berberine; Berberine Alkaloids; Drug Compounding; Drug Delivery Systems; Fibroblasts; HeLa Cells; Humans; Lipid Bilayers; Mitochondria; Models, Chemical; Molecular Targeted Therapy; Phytotherapy; Plant Preparations; Plastoquinone	2011
Determination of berberine, palmatine and jatrorrhizine in rabbit plasma by liquid chromatography-electrospray ionization-mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2011, Dec-15, Volume: 56, Issue:5 Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Calibration; Chromatography, Liquid; Drugs, Chinese Herbal; Limit of Detection; Male; Quality Control; Rabbits; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization	2011
Determination of protoberberine alkaloids in Rhizoma Coptidis by ERETIC ¹H NMR method. Journal of pharmaceutical and biomedical analysis, 2012, Feb-23, Volume: 60 Topics: Berberine; Berberine Alkaloids; Coptis; Limit of Detection; Magnetic Resonance Spectroscopy	2012
High-performance liquid chromatography-electrospray ionization-mass spectrometry ligand fishing assay: a method for screening triplex DNA binders from natural plant extracts. Analytical chemistry, 2012, Mar-06, Volume: 84, Issue:5 Topics: Berberine; Berberine Alkaloids; Biotinylation; Chromatography, High Pressure Liquid; DNA; Ligands; Oligodeoxyribonucleotides; Phellodendron; Plant Extracts; Spectrometry, Mass, Electrospray Ionization	2012
Isoquinoline alkaloids from Tinospora cordifolia inhibit rat lens aldose reductase. Phytotherapy research : PTR, 2012, Volume: 26, Issue:9 Topics: Aldehyde Reductase; Animals; Aporphines; Berberine; Berberine Alkaloids; Enzyme Inhibitors; In Vitro Techniques; Lens, Crystalline; Male; Plant Extracts; Rats; Rats, Wistar; Tinospora	2012
[Studies on intestinal absorption of alkaloids in Coptis chinensis by in situ single-pass perfused rat intestinal model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:24 Topics: Alkaloids; Animals; Berberine; Berberine Alkaloids; Coptis; Intestinal Absorption; Male; Perfusion; Rats; Rats, Wistar	2011
[Effect of different compatibility of Wuji Wan on bile excretion of representative ingredient]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:23 Topics: Animals; Berberine; Berberine Alkaloids; Bile; Chromatography, Liquid; Drug Compounding; Drugs, Chinese Herbal; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Time Factors	2011
[Distribution of four alkaloids in plants of Berberis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2004, Volume: 27, Issue:2 Topics: Benzylisoquinolines; Berberine; Berberine Alkaloids; Berberis; China; Chromatography, High Pressure Liquid; Plant Bark; Plant Roots; Plant Stems; Plants, Medicinal; Reproducibility of Results; Seasons	2004
Analysis of four alkaloids of Coptis chinensis in rat plasma by high performance liquid chromatography with electrochemical detection. Analytica chimica acta, 2012, Aug-06, Volume: 737 Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Calibration; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Coptis; Coptis chinensis; Drugs, Chinese Herbal; Electrochemical Techniques; Electrodes; Limit of Detection; Rats	2012
[Quantitative analysis of four alkaloids in Xianglian preparations by QAMS method]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:11 Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Evaluation Studies as Topic; Quality Control; Reference Standards	2011
[Impact on absorption of berberine and palmatine in different compatibilities of Wuji pill]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:7 Topics: Animals; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Evodia; Intestinal Absorption; Male; Rats	2012
Discrimination of Phellodendron amurense and P. chinense based on DNA analysis and the simultaneous analysis of alkaloids. Archives of pharmacal research, 2012, Volume: 35, Issue:6 Topics: Alkaloids; Base Sequence; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; DNA, Intergenic; DNA, Plant; Drugs, Chinese Herbal; Limit of Detection; Molecular Sequence Data; Phellodendron; Plant Bark; Plants, Medicinal; Quality Control; Random Amplified Polymorphic DNA Technique; Reproducibility of Results; Ribulose-Bisphosphate Carboxylase	2012
Quality evaluation and species differentiation of Rhizoma coptidis by using proton nuclear magnetic resonance spectroscopy. Analytica chimica acta, 2012, Oct-17, Volume: 747 Topics: Berberine; Berberine Alkaloids; Coptis; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Multivariate Analysis; Plant Extracts; Principal Component Analysis; Rhizome; Species Specificity	2012
Synthesis and cytotoxicity evaluation of 13-n-alkyl berberine and palmatine analogues as anticancer agents. Molecules (Basel, Switzerland), 2012, Sep-25, Volume: 17, Issue:10 Topics: Animals; Antineoplastic Agents; Berberine; Berberine Alkaloids; Cell Line, Tumor; Hep G2 Cells; Humans; Inhibitory Concentration 50; Male; Mice; Xenograft Model Antitumor Assays	2012
Derivatives of the cationic plant alkaloids berberine and palmatine amplify protonophorous activity of fatty acids in model membranes and mitochondria. Mitochondrion, 2013, Volume: 13, Issue:5 Topics: Alkaloids; Berberine; Berberine Alkaloids; Cations; Fatty Acids; Hydrogen; Membranes; Mitochondria; Plastoquinone	2013
Binding of plant alkaloids berberine and palmatine to serum albumins: a thermodynamic investigation. Molecular biology reports, 2013, Volume: 40, Issue:1 Topics: Berberine; Berberine Alkaloids; Calorimetry; Circular Dichroism; Humans; Protein Binding; Serum Albumin; Sodium; Spectrometry, Fluorescence; Temperature; Thermodynamics	2013
Safety evaluation of main alkaloids from Rhizoma Coptidis. Journal of ethnopharmacology, 2013, Jan-09, Volume: 145, Issue:1 Topics: 3T3-L1 Cells; Alkaloids; Animals; Berberine; Berberine Alkaloids; Blood Proteins; Body Weight; Coptis; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Hep G2 Cells; Humans; Inhibitory Concentration 50; Lethal Dose 50; Male; Mice; Organ Size; Rats; Rats, Sprague-Dawley; Rhizome	2013
[Classification study of Coptis chinensis based on quantitative physical property characteristics of appearance and internal quality evaluation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:20 Topics: Berberine; Berberine Alkaloids; Coptis; Drugs, Chinese Herbal; Quality Control	2012
A new antibacterial denitroaristolochic acid from the tubers of Stephania succifera. Journal of Asian natural products research, 2013, Volume: 15, Issue:3 Topics: Alkaloids; Anti-Bacterial Agents; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenanthrenes; Plant Tubers; Staphylococcus aureus; Stephania	2013
[Intestinal absorption of different combinations of active compounds from Gegenqinlian decoction by rat single pass intestinal perfusion in situ]. Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:12 Topics: Animals; Berberine; Berberine Alkaloids; Coptis; Drug Combinations; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glycyrrhiza; Intestinal Absorption; Intestinal Mucosa; Isoflavones; Male; Plant Roots; Plants, Medicinal; Pueraria; Rats; Rats, Sprague-Dawley; Rhizome; Scutellaria baicalensis	2012
Novel pharmacokinetic studies of the Chinese formula Huang-Lian-Jie-Du-Tang in MCAO rats. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Jul-15, Volume: 20, Issue:10 Topics: Animals; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Flavanones; Flavonoids; Infarction, Middle Cerebral Artery; Iridoids; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution	2013
[Study on metabolism of Coptis chinensis alkaloids from different compatibility of Wuji Wan in human intestinal flora]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:3 Topics: Anaerobiosis; Bacteria; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Evodia; Feces; Intestinal Absorption; Intestinal Mucosa; Intestines; Paeonia; Time Factors	2013
Mechanism study of goldenseal-associated DNA damage. Toxicology letters, 2013, Jul-31, Volume: 221, Issue:1 Topics: Alkaloids; Berberine; Berberine Alkaloids; Comet Assay; DNA; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Gene Expression Regulation, Enzymologic; Gene Silencing; Hep G2 Cells; Hepatocytes; Histones; Humans; Hydrastis; Mutagens; Plant Extracts; RNA, Small Interfering; Structure-Activity Relationship	2013
Inhibition of CYP1 by berberine, palmatine, and jatrorrhizine: selectivity, kinetic characterization, and molecular modeling. Toxicology and applied pharmacology, 2013, Nov-01, Volume: 272, Issue:3 Topics: Aryl Hydrocarbon Hydroxylases; Berberine; Berberine Alkaloids; Computer Simulation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Humans; Models, Molecular; Structural Homology, Protein	2013
Selective extraction of berberine and palmatine from Huangbai powder. Pakistan journal of pharmaceutical sciences, 2013, Volume: 26, Issue:5 Topics: Acetates; Berberine; Berberine Alkaloids; Chemical Fractionation; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Hexanes; Methylene Chloride; Powders; Solvents	2013
[Screening of the active ingredients in natural products by capillary electrophoresis and high performance liquid chromatography-mass spectrometry]. Se pu = Chinese journal of chromatography, 2013, Volume: 31, Issue:7 Topics: Acetylcholinesterase; Alkaloids; Berberine; Berberine Alkaloids; Biological Products; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Electrophoresis, Capillary; Tandem Mass Spectrometry	2013
Pharmacokinetic comparisons of berberine and palmatine in normal and metabolic syndrome rats. Journal of ethnopharmacology, 2014, Volume: 151, Issue:1 Topics: Administration, Oral; Animals; Area Under Curve; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Half-Life; Male; Metabolic Syndrome; Molecular Structure; Random Allocation; Rats	2014
Comparative pharmacokinetics of active alkaloids after oral administration of Rhizoma Coptidis extract and Wuji Wan formulas in rat using a UPLC-MS/MS method. European journal of drug metabolism and pharmacokinetics, 2015, Volume: 40, Issue:1 Topics: Administration, Oral; Animals; Area Under Curve; Berberine; Berberine Alkaloids; Biological Availability; Chromatography, Liquid; Coptis chinensis; Drug Interactions; Drugs, Chinese Herbal; Half-Life; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Metabolic Clearance Rate; Phytotherapy; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry	2015
Palmatine activates AhR and upregulates CYP1A activity in HepG2 cells but not in human hepatocytes. Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:4 Topics: Basic Helix-Loop-Helix Transcription Factors; Berberine; Berberine Alkaloids; Cell Survival; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Molecular Structure; Receptors, Aryl Hydrocarbon	2014
[Microcalorimetric investigation on the interaction of six alkaloids from rhizoma coptidis]. Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:12 Topics: Alkaloids; Berberine; Berberine Alkaloids; Coptis; Drug Interactions; Drug Synergism; Plants, Medicinal; Quality Control; Rhizome; Shigella dysenteriae	2013
Synergistic inhibition on acetylcholinesterase by the combination of berberine and palmatine originally isolated from Chinese medicinal herbs. Journal of molecular neuroscience : MN, 2014, Volume: 53, Issue:3 Topics: Acetylcholinesterase; Berberine; Berberine Alkaloids; Cholinesterase Inhibitors; Drug Synergism; Drugs, Chinese Herbal; HEK293 Cells; Humans	2014
Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of huang-lian-jie-du-tang decoction. Journal of Asian natural products research, 2014, Volume: 16, Issue:5 Topics: Administration, Oral; Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Iridoids; Molecular Structure; Rats; Rats, Sprague-Dawley	2014
Ultrafiltration liquid chromatography combined with high-speed countercurrent chromatography for screening and isolating potential α-glucosidase and xanthine oxidase inhibitors from Cortex Phellodendri. Journal of separation science, 2014, Volume: 37, Issue:18 Topics: alpha-Glucosidases; Benzoxepins; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Countercurrent Distribution; Drugs, Chinese Herbal; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Limonins; Molecular Structure; Phellodendron; Ultrafiltration; Xanthine Oxidase	2014
Metabolic profiling analysis of berberine, palmatine, jatrorrhizine, coptisine and epiberberine in zebrafish by ultra-high performance liquid chromatography coupled with LTQ Orbitrap mass spectrometer. Xenobiotica; the fate of foreign compounds in biological systems, 2015, Volume: 45, Issue:4 Topics: Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Metabolomics; Models, Animal; Tandem Mass Spectrometry; Zebrafish	2015
A competitive strategy based on cucurbit[7]uril supramolecular interaction for simple and sensitive detection of dibucaine. Talanta, 2015, Volume: 132 Topics: Anesthetics, Local; Berberine; Berberine Alkaloids; Binding, Competitive; Bridged-Ring Compounds; Dibucaine; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Limit of Detection; Solutions; Spectrometry, Fluorescence; Thermodynamics	2015
Two-stage fractionation of polar alkaloids from Rhizoma coptidis by countercurrent chromatography considering the strategy of reactive extraction. Journal of chromatography. A, 2015, Jan-23, Volume: 1378 Topics: Alkaloids; Berberine; Berberine Alkaloids; Chemical Fractionation; Countercurrent Distribution; Drugs, Chinese Herbal; Plants, Medicinal; Ranunculaceae	2015
A room-temperature protocol to access isoquinolines through Ag(I) catalysed annulation of o-(1-alkynyl)arylaldehydes and ketones with NH4OAc: elaboration to berberine and palmatine. Organic & biomolecular chemistry, 2015, Mar-28, Volume: 13, Issue:12 Topics: Acetates; Aldehydes; Berberine; Berberine Alkaloids; Catalysis; Isoquinolines; Ketones; Silver; Temperature	2015
Novel molecularly imprinted magnetic nanoparticles for the selective extraction of protoberberine alkaloids in herbs and rat plasma. Journal of separation science, 2015, Volume: 38, Issue:12 Topics: Administration, Oral; Adsorption; Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Ferric Compounds; Hydrogen-Ion Concentration; Magnetite Nanoparticles; Nanotechnology; Phellodendron; Plant Bark; Plant Extracts; Polymers; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared	2015
Simultaneous quantification and antiatherosclerosis effect of the traditional Korean medicine, Hwangryunhaedok-tang. BMC complementary and alternative medicine, 2015, Apr-08, Volume: 15 Topics: Animals; Antioxidants; Atherosclerosis; Berberine; Berberine Alkaloids; Biphenyl Compounds; Cell Proliferation; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Flavonoids; Gardenia; Iridoids; Lipoproteins, LDL; Medicine, Korean Traditional; Muscle, Smooth, Vascular; Phellodendron; Phytotherapy; Picrates; Platelet-Derived Growth Factor; Rats; Regression Analysis; Scutellaria	2015
Antifungal activity of berberine hydrochloride and palmatine hydrochloride against Microsporum canis -induced dermatitis in rabbits and underlying mechanism. BMC complementary and alternative medicine, 2015, Jun-09, Volume: 15 Topics: Animals; Antifungal Agents; Berberine; Berberine Alkaloids; Cell Membrane; Dermatitis; Genes, Fungal; Male; Microbial Sensitivity Tests; Microsporum; Phellodendron; Phytotherapy; Plant Extracts; Rabbits; Real-Time Polymerase Chain Reaction; RNA, Messenger; Up-Regulation	2015
Interaction of six protoberberine alkaloids with human organic cation transporters 1, 2 and 3. Xenobiotica; the fate of foreign compounds in biological systems, 2016, Volume: 46, Issue:2 Topics: 1-Methyl-4-phenylpyridinium; Animals; Berberine; Berberine Alkaloids; Cells, Cultured; Chromatography, Liquid; Dogs; Humans; Inhibitory Concentration 50; Madin Darby Canine Kidney Cells; Octamer Transcription Factor-3; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Polymorphism, Genetic; Tandem Mass Spectrometry	2016
Pharmacokinetics of a multicomponent herbal preparation in healthy Chinese and African volunteers. Scientific reports, 2015, Aug-13, Volume: 5 Topics: Adult; Alkaloids; Aporphines; Asian People; Benzylisoquinolines; Berberine; Berberine Alkaloids; Black People; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Healthy Volunteers; Humans; Male; Middle Aged; Spectrometry, Mass, Electrospray Ionization	2015
A series of strategies for solving the shortage of reference standards for multi-components determination of traditional Chinese medicine, Mahoniae Caulis as a case. Journal of chromatography. A, 2015, Sep-18, Volume: 1412 Topics: Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Mahonia; Quality Control; Reference Standards	2015
HPLC-PDA Method for Simultaneous Determination of Nine Marker Components in Banhasasim-Tang. Journal of chromatographic science, 2016, Volume: 54, Issue:3 Topics: Acetonitriles; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Glucosides; Glycyrrhizic Acid; Humans; Limit of Detection; Medicine, Korean Traditional; Observer Variation; Pinellia; Plants, Medicinal; Reproducibility of Results; Solvents; Trifluoroacetic Acid; Water	2016
[Screening of Active Fractions from Huanglian Jiedu Decoction against Primary Neuron Injury after Oxygen-Glucose Deprivation]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2015, Volume: 35, Issue:8 Topics: Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucose; Iridoids; Models, Animal; Neurons; Oxygen; Rats; Reperfusion Injury	2015
11-Hydroxylation of Protoberberine by the Novel Berberine-Utilizing Aerobic Bacterium Sphingobium sp. Strain BD3100. Journal of natural products, 2015, Dec-24, Volume: 78, Issue:12 Topics: Benzoflavones; Berberine; Berberine Alkaloids; Cytochrome P-450 Enzyme Inhibitors; Hydroxylation; Japan; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Sphingomonadaceae	2015
Evaluation of Anthelmintic Activity and Composition of Pumpkin (Cucurbita pepo L.) Seed Extracts-In Vitro and in Vivo Studies. International journal of molecular sciences, 2016, Sep-01, Volume: 17, Issue:9 Topics: Amino Acids; Animals; Antinematodal Agents; Berberine; Berberine Alkaloids; Cucurbita; Fatty Acids; Mice; Plant Extracts; Plant Proteins; Rhabditida; Seeds	2016
Visualization of Stepwise Drug-Micelle Aggregate Formation and Correlation with Spectroscopic and Calorimetric Results. The journal of physical chemistry. B, 2016, 11-17, Volume: 120, Issue:45 Topics: Berberine; Berberine Alkaloids; Calorimetry; Micelles; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics	2016
Pharmacokinetics study of Erhuang decoction extracts in rats by HPLC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, Aug-01, Volume: 1059 Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis chinensis; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhetinic Acid; Glycyrrhiza; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Scutellaria baicalensis; Tandem Mass Spectrometry	2017
Comparative pharmacokinetics study of five alkaloids in rat plasma and related compound-herb interactions mechanism after oral administration of Shuanghua Baihe tablets. Natural product research, 2018, Volume: 32, Issue:17 Topics: Administration, Oral; Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, Liquid; Drugs, Chinese Herbal; Medicine, Chinese Traditional; Rats; Tablets; Tandem Mass Spectrometry	2018
Evaluation of anti-sepsis activity by compounds with high affinity to lipid a from HuanglianJiedu decoction. Immunopharmacology and immunotoxicology, 2017, Volume: 39, Issue:6 Topics: Animals; Berberine; Berberine Alkaloids; Cell Line; Drugs, Chinese Herbal; Flavonoids; Interleukin-6; Iridoids; Lipid A; Lipopolysaccharides; Mice; RAW 264.7 Cells; Sepsis; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha	2017
[Pharmacokinetics and oral bioavailability of palmatine and jatrorrhizine in Huangteng in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:14 Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Biological Availability; Drugs, Chinese Herbal; Rats	2017
Berberine Activates Aryl Hydrocarbon Receptor but Suppresses CYP1A1 Induction through miR-21-3p Stimulation in MCF-7 Breast Cancer Cells. Molecules (Basel, Switzerland), 2017, Oct-28, Volume: 22, Issue:11 Topics: Basic Helix-Loop-Helix Transcription Factors; Berberine; Berberine Alkaloids; Breast Neoplasms; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; MicroRNAs; Molecular Structure; Receptors, Aryl Hydrocarbon	2017
Construction of an optimized method for quality evaluation and species discrimination of Coptidis Rhizoma by ion-pair high performance liquid chromatography combined with response surface methodology. Journal of pharmaceutical and biomedical analysis, 2018, May-10, Volume: 153 Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Ions; Reference Standards; Rhizome	2018
Modification and Characterization of Fe₃O₄ Nanoparticles for Use in Adsorption of Alkaloids. Molecules (Basel, Switzerland), 2018, Mar-02, Volume: 23, Issue:3 Topics: Adsorption; Alginates; Alkaloids; Berberine; Berberine Alkaloids; Ferrosoferric Oxide; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Isocyanates; Magnetite Nanoparticles; Silanes; Surface Properties	2018
Natural Aromatic Compounds as Scaffolds to Develop Selective G-Quadruplex Ligands: From Previously Reported Berberine Derivatives to New Palmatine Analogues. Molecules (Basel, Switzerland), 2018, Jun-12, Volume: 23, Issue:6 Topics: Berberine; Berberine Alkaloids; DNA; G-Quadruplexes; Ligands; Models, Molecular; Molecular Structure	2018
Berberine and palmatine inhibit the growth of human rhabdomyosarcoma cells. Bioscience, biotechnology, and biochemistry, 2020, Volume: 84, Issue:1 Topics: Antineoplastic Agents; Berberine; Berberine Alkaloids; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p57; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; G1 Phase Cell Cycle Checkpoints; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Molecular Conformation; Molecular Docking Simulation; Phellodendron; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal	2020
[Simultaneous Quantitative Analysis of Berberine and Other Alkaloids in Powdered Phellodendron Bark]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:11 Topics: Alkaloids; Berberine; Berberine Alkaloids; China; Chromatography, High Pressure Liquid; Drug Stability; Japan; Phellodendron; Plant Bark; Powder Diffraction; Quality Control	2019
Characterization of Bioscience, biotechnology, and biochemistry, 2020, Volume: 84, Issue:6 Topics: Berberine; Berberine Alkaloids; Biodegradation, Environmental; Burkholderia; Coptis; Hydroxylation; Rhizosphere; Soil Microbiology	2020
Identification of a multi-component berberine 11-hydroxylase from Bioscience, biotechnology, and biochemistry, 2020, Volume: 84, Issue:6 Topics: Bacterial Proteins; Berberine; Berberine Alkaloids; Burkholderia; Escherichia coli; Ferredoxins; Genome, Bacterial; Hydroxylation; Microorganisms, Genetically-Modified; Mixed Function Oxygenases; Oxidoreductases; Phylogeny; Recombinant Proteins	2020
Polymorphism of human telomeric quadruplexes with drugs: a multi-technique biophysical study. Physical chemistry chemical physics : PCCP, 2020, May-27, Volume: 22, Issue:20 Topics: Berberine; Berberine Alkaloids; Circular Dichroism; DNA; G-Quadruplexes; Humans; Ligands; Scattering, Small Angle; Spectrum Analysis, Raman; X-Ray Diffraction	2020
The Influence of Palmatine Isolated from Cells, 2020, 05-16, Volume: 9, Issue:5 Topics: Animals; Behavior, Animal; Berberine; Berberine Alkaloids; Berberis; Blood-Brain Barrier; Brain-Derived Neurotrophic Factor; Electroencephalography; Larva; Locomotion; Pentylenetetrazole; Plant Extracts; Proto-Oncogene Proteins c-fos; Quantitative Structure-Activity Relationship; Seizures; Zebrafish	2020
Highly efficient synthesis and monoamine oxidase B inhibitory profile of demethyleneberberine, columbamine and palmatine. Neurochemistry international, 2020, Volume: 139 Topics: Berberine; Berberine Alkaloids; Binding Sites; Dose-Response Relationship, Drug; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Plant Extracts	2020
Biological Response Profiling Reveals the Functional Differences of Main Alkaloids in Rhizoma Coptidis. Molecules (Basel, Switzerland), 2021, Dec-06, Volume: 26, Issue:23 Topics: 3T3-L1 Cells; Animals; Berberine; Berberine Alkaloids; Cell Cycle; Cell Proliferation; Chromatography, High Pressure Liquid; Coptis; Coptis chinensis; Drugs, Chinese Herbal; Gene Expression Regulation; Hep G2 Cells; Humans; Mice; RAW 264.7 Cells; Rhizome; Signal Transduction; Transcriptome	2021
Immobilization of peroxisome proliferator-activated receptor gamma and the application in screening modulators of the receptor from herbal medicine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2022, Feb-01, Volume: 1190 Topics: Berberine; Berberine Alkaloids; Coptis chinensis; Drugs, Chinese Herbal; Fluorescence Resonance Energy Transfer; Herbal Medicine; Humans; PPAR gamma; Protein Binding	2022
An Exosome-Based Therapeutic Strategy Targeting Neuroinflammation in Alzheimer's Disease with Berberine and Palmatine. Drug design, development and therapy, 2023, Volume: 17 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Berberine; Cytokines; Exosomes; Mice; Neuroinflammatory Diseases; Plaque, Amyloid	2023