berberine and methotrexate

berberine has been researched along with methotrexate in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Gao, F; Wang, T; Xiao, J; Zhang, X1
Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT1
Hozayen, WG; Mahmoud, AM; Ramadan, SM1
Esmaeilizadeh, M; Fatemi, I; Ghaznavi, H; Goudarzi, M; Kalantar, H; Mehrzadi, S1
Ahmed, MA; Ali, FEM; Hassanein, EHM; Kamel, EO1
Hassanein, EHM; Hemeida, RAM; Khalaf, MM; Mohamed, WR; Sayed, AM; Shalkami, AS1

Reviews

2 review(s) available for berberine and methotrexate

ArticleYear
Quinolone hybrids and their anti-cancer activities: An overview.
    European journal of medicinal chemistry, 2019, Mar-01, Volume: 165

    Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Quinolones; Structure-Activity Relationship

2019
Drugs for the Treatment of Zika Virus Infection.
    Journal of medicinal chemistry, 2020, 01-23, Volume: 63, Issue:2

    Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection

2020

Other Studies

5 other study(ies) available for berberine and methotrexate

ArticleYear
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 94

    Topics: Animals; Apoptosis; Berberine; Chemical and Drug Induced Liver Injury; Heme Oxygenase (Decyclizing); Male; Methotrexate; NF-E2-Related Factor 2; Oxidative Stress; PPAR gamma; Rats, Wistar; Signal Transduction

2017
Hepatoprotective effect of berberine against methotrexate induced liver toxicity in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Alanine Transaminase; Animals; Antimetabolites, Antineoplastic; Aspartate Aminotransferases; Berberine; Chemical and Drug Induced Liver Injury; Glutathione; Male; Methotrexate; Oxidative Stress; Rats; Rats, Wistar

2018
Berberine and/or zinc protect against methotrexate-induced intestinal damage: Role of GSK-3β/NRF2 and JAK1/STAT-3 signaling pathways.
    Life sciences, 2021, Sep-15, Volume: 281

    Topics: Animals; Berberine; Forkhead Box Protein O3; Glycogen Synthase Kinase 3 beta; Inflammation; Intestines; Janus Kinase 1; Male; Methotrexate; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction; Sirtuin 1; STAT3 Transcription Factor; Zinc

2021
Hepatoprotective effects of phytochemicals berberine and umbelliferone against methotrexate-induced hepatic intoxication: experimental studies and in silico evidence.
    Environmental science and pollution research international, 2021, Volume: 28, Issue:47

    Topics: Animals; Berberine; Humans; Methotrexate; Molecular Docking Simulation; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Phytochemicals; Rats; Signal Transduction; Umbelliferones

2021