berberine has been researched along with methotrexate in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Gao, F; Wang, T; Xiao, J; Zhang, X | 1 |
| Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT | 1 |
| Hozayen, WG; Mahmoud, AM; Ramadan, SM | 1 |
| Esmaeilizadeh, M; Fatemi, I; Ghaznavi, H; Goudarzi, M; Kalantar, H; Mehrzadi, S | 1 |
| Ahmed, MA; Ali, FEM; Hassanein, EHM; Kamel, EO | 1 |
| Hassanein, EHM; Hemeida, RAM; Khalaf, MM; Mohamed, WR; Sayed, AM; Shalkami, AS | 1 |
2 review(s) available for berberine and methotrexate
| Article | Year |
|---|---|
Quinolone hybrids and their anti-cancer activities: An overview.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Quinolones; Structure-Activity Relationship | 2019 |
Drugs for the Treatment of Zika Virus Infection.
Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection | 2020 |
5 other study(ies) available for berberine and methotrexate
| Article | Year |
|---|---|
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats.
Topics: Animals; Apoptosis; Berberine; Chemical and Drug Induced Liver Injury; Heme Oxygenase (Decyclizing); Male; Methotrexate; NF-E2-Related Factor 2; Oxidative Stress; PPAR gamma; Rats, Wistar; Signal Transduction | 2017 |
Hepatoprotective effect of berberine against methotrexate induced liver toxicity in rats.
Topics: Alanine Transaminase; Animals; Antimetabolites, Antineoplastic; Aspartate Aminotransferases; Berberine; Chemical and Drug Induced Liver Injury; Glutathione; Male; Methotrexate; Oxidative Stress; Rats; Rats, Wistar | 2018 |
Berberine and/or zinc protect against methotrexate-induced intestinal damage: Role of GSK-3β/NRF2 and JAK1/STAT-3 signaling pathways.
Topics: Animals; Berberine; Forkhead Box Protein O3; Glycogen Synthase Kinase 3 beta; Inflammation; Intestines; Janus Kinase 1; Male; Methotrexate; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction; Sirtuin 1; STAT3 Transcription Factor; Zinc | 2021 |
Hepatoprotective effects of phytochemicals berberine and umbelliferone against methotrexate-induced hepatic intoxication: experimental studies and in silico evidence.
Topics: Animals; Berberine; Humans; Methotrexate; Molecular Docking Simulation; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Phytochemicals; Rats; Signal Transduction; Umbelliferones | 2021 |