berberine has been researched along with jatrorrhizine in 130 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (3.85) | 18.7374 |
| 1990's | 4 (3.08) | 18.2507 |
| 2000's | 37 (28.46) | 29.6817 |
| 2010's | 74 (56.92) | 24.3611 |
| 2020's | 10 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y | 1 |
| Kim, JH; Kim, YH; Lee, WS; Ryu, YB | 1 |
| Bae, GU; Jeong, JH; Lee, H; Lee, SJ; Ryu, JH; Tuong, LT | 1 |
| Fu, DJ; Li, J; Yu, B | 1 |
| Chen, ZL; Zhang, JS | 1 |
| Ma, Y; Tang, X; Zhang, Z; Zhou, R | 1 |
| Feng, YM; Xu, KM | 1 |
| Fang, XP; Li, D; Shuai, H; Wang, TZ; Xie, CK; Zhang, H | 1 |
| Fang, DC; Han, H | 1 |
| Klayman, DL; Vennerstrom, JL | 1 |
| Lassila, V; Mengata, DE; Njimi, T; Virtanen, P | 1 |
| Khosa, RL; Sahai, M; Sarma, DN | 1 |
| Liu, S; Ren, L; Yang, L; Zhang, H | 1 |
| Jiang, SH; Pan, JF; Ren, JY; Yu, C; Zeng, JF; Zhang, H; Zhu, DY | 1 |
| Fuchsberger, N; Hajnická, V; Kost'álová, D; Sochorová, R; Svecová, D; Tóth, J | 1 |
| Cernáková, M; Drímal, J; Kettmann, V; Kost'álová, D; Plodová, M; Tóth, J | 1 |
| Wei, L; Yang, D; Zhou, H | 1 |
| Dai, KJ; Luo, JB; Luo, QZ; Ma, AD | 1 |
| Cheng, YY; Peng, MX; Wu, YJ | 1 |
| Brezová, V; Dvoranová, D; Kost'álová, D | 1 |
| Kettmann, V; Kost'álová, D; Kotulová, D; Labudová, D; Slobodníková, L | 1 |
| Guo, M; Liu, S; Liu, Z; Wang, D | 1 |
| Di, DL; Jiang, SX; Liu, YW; Ma, ZG | 1 |
| Li, ZH; Qin, HL; Wang, P; Yang, JR | 1 |
| Chen, XG; Guo, XK; Hu, ZD; Jia, L; Lin, SY; Wen, HG | 1 |
| Chen, X; He, W; Hu, Z; Li, Y; Liu, J; Sheng, F | 1 |
| Chen, SJ; Huang, XP; Ma, KS; Qin, SY; Zhong, GY | 1 |
| Dong, J; Hu, J; Tian, R; Wu, R; Xie, C; Zou, H | 1 |
| Tao, J; Ye, W; Zhang, X; Zhao, S | 1 |
| Fu, Q; Fu, Y; Hu, B; Tang, Q; Xiang, J | 1 |
| Bai, LP; Cai, Z; Chen, WH; Jiang, ZH; Long, YH; Pang, JY; Qin, Y; Xu, ZL | 1 |
| Li, Y; Liu, Q; Liu, Y; Yao, S | 1 |
| Jin, J; Ma, JS; Sun, J; Wang, HS; Wen, QH; Zhang, HG; Zhou, QL | 1 |
| Akao, T; Hattori, M; Nakamura, N; Zuo, F | 1 |
| Chen, HX; Chen, Y; Han, FM; Zhu, MM | 1 |
| Sheng, YX; Sun, SQ; Xu, JT; Zhang, JL | 1 |
| Lei, P; Li, XZ; Liu, S | 1 |
| Liang, X; Ren, L; Xu, Q; Xue, X; Zhang, F | 1 |
| Cui, M; Guo, X; Liu, S; Liu, Z; Song, F; Wang, Z | 1 |
| Bi, K; Deng, Y; Li, S; Liao, Q; Pan, B; Xie, Z | 1 |
| Cao, XG; Li, XG; Liang, YT; Sun, QL; Wang, LJ; Ye, XL; Yu, G; Zhang, HS; Zhou, JZ | 1 |
| Bi, KS; Deng, YT; Jiang, XF; Liao, QF; Xie, ZY; Yao, MC | 1 |
| Chen, Y; Han, F; Wu, W; Zhang, Y | 1 |
| Cai, CT; Cai, ZQ; Liu, GZ; Luo, Y; Yang, ZX; Zhang, J | 1 |
| Cao, XG; Chen, Z; Li, XG; Niu, XH; Sun, QL; Wang, LJ; Ye, XL; Yu, G; Zhang, BS | 1 |
| Chen, X; Chu, H; Li, X; Li, Y; Liu, G; Ye, X; Zhou, J; Zhu, Y | 1 |
| Fan, B; Peng, J; Wu, X; Yu, Y | 1 |
| Wu, DZ; Yu, X; Yuan, JY; Zhang, DG | 1 |
| Chen, X; Duan, H; Hu, Y; Mu, X | 1 |
| Chen, JH; Hu, FD; Huang, XY; Zhai, HL | 1 |
| Bhadra, K; Kumar, GS | 1 |
| Cheng, MC; Liu, YQ; Wang, LX; Xiao, HB | 1 |
| Fu, J; Guo, L; Pan, L; Zhu, H | 1 |
| Cai, F; Chen, W; Feng, J; Jiang, B; Tao, X; Wei, H; Xu, W | 1 |
| Guo, Y; Tan, X; Zhong, Y | 1 |
| Cai, B; Fu, X; Li, J; Liu, X; Yin, D; Zhang, Y | 1 |
| Cai, L; Luo, W; Zhang, Q; Zhong, G | 1 |
| Gao, C; Jiang, J; Qiu, F; Tan, Y; Zhang, X | 1 |
| Jiang, JD; Kong, WJ; Li, Y; Li, YH; Li, ZR; Ren, G; Song, DQ; Wang, YM; Wang, YX; Yang, P; Yi, H | 1 |
| Hu, Z; Ji, G; Wu, D; Xie, J; Yuan, J; Zhou, J | 1 |
| Chen, SG; He, F; Huang, JT; Luo, T; Song, EL; Wang, HQ; Xu, J; Zhang, H; Zhang, WW | 1 |
| Du, LM; Wu, H; Zhang, LB | 1 |
| Chen, HL; Chen, XG; Hu, SQ; Li, HH; Lü, WJ; Ma, YH; Zhu, HD | 1 |
| Li, Z; Liu, F; Shi, X; Zhong, M | 1 |
| Chen, LQ; Ding, PL; Li, YG; Lu, Y | 1 |
| Mishra, S; Patel, MB | 1 |
| Cao, A; Hu, Z; Wu, D; Zhang, B; Zhou, J | 1 |
| Cheng, N; Luo, H; Ma, B; Ma, Y; Shi, R; Wang, X; Wu, D; Zhou, H | 1 |
| Di, D; Jiang, S; Ma, Z; Wang, Q | 1 |
| Chen, Z; Liu, L | 1 |
| Ko, BS; Lee, HW; Lee, JH; Lee, MY; Lee, SH; Li, Y; Moon, DC; Park, JY; Ryuk, JA; Seo, CS; Son, JK; Zheng, MS | 1 |
| Fan, G; Lai, XR; Luo, WZ; Tang, C; Yue, QH; Zhang, MY; Zhang, Y; Zhou, XD | 1 |
| Jiang, P; Liu, L; Liu, R; Wang, L; Wang, S; Xiang, L; Zhang, W | 1 |
| He, F; Jiang, W; Kong, Y; Li, S; Luo, T; Wang, HQ; Xu, J | 1 |
| Cheng, N; Ma, Y; Shi, R; Tan, Z; Wang, C; Wang, X; Zhong, J; Zhu, R | 1 |
| Cheng, N; Ma, B; Ma, Y; Shi, R; Wang, C; Wang, X; Wu, D; Zhou, H | 1 |
| Qin, S; Wang, J; Xu, Y | 1 |
| An, R; Wang, XH; Xu, RC; Zhang, H; Zhang, YZ | 1 |
| Fan, X; Hu, M; Su, D; Xu, Y; Yu, J | 1 |
| Fan, XY; Hu, YJ; Li, HY; Li, PQ; Mi, R; Ouyang, Y; Yu, XC | 1 |
| Cao, Z; Guo, P; Liu, R; Pan, Y; Yang, P; Zhang, G; Zhou, Q | 1 |
| Chang, CY; Chang, YP; Lo, SN; Tsai, KC; Ueng, YF; Wu, TS | 1 |
| Bai, AM; Fan, XY; Hu, YJ; Mi, R; Ouyang, Y | 1 |
| Dong, C; Jiao, Y; Li, J | 1 |
| Kang, J; Zhang, Y | 1 |
| Chen, WJ; Feng, R; Fu, J; He, CY; He, WY; Huang, M; Jiang, JD; Ma, C; Ma, JY; Shou, JW; Sun, YP; Tan, XS; Wang, Y | 1 |
| Bin, W; Cao, S; Kang, N; Qiu, F; Wang, Y; Xu, P; Yan, J; Zhou, Y | 1 |
| Li, BC; Li, JX; Wang, JY; Wang, RL; Xiao, XH; Yan, D; Zhang, LL | 1 |
| Liu, JX; Ma, ZT; Yang, XW; Zhang, Y | 1 |
| Li, K; Li, Y; Wen, J; Ye, B; Ye, Z | 1 |
| He, K; Li, X; Ning, N; Pang, J; Wang, D; Wang, Y; Wu, H; Xue, D; Ye, X; Zou, Z | 1 |
| Bian, B; Han, L; Li, Y; Ren, W; Si, N; Wang, H; Wei, X; Xin, S; Yang, J; Zhao, H; Zuo, R | 1 |
| Feng, Y; Fu, Z; Liang, S; Liang, XG; Wang, Y; Wang, YJ; Wu, F | 1 |
| Cai, F; Hu, P; Li, Y; Wang, Y; Zhang, H; Zhang, M | 1 |
| Bao, T; Chen, Z; Meng, J; Zhang, W | 1 |
| Bai, M; Jiang, H; Li, L; Song, F; Sun, S; Weng, Y; Zeng, S; Zhou, H; Zhou, S | 1 |
| Alolga, RN; Chen, Y; Fan, Y; Lelu Kakila, J; Li, J; Li, P; Qi, LW; Zhang, G; Zhao, YJ | 1 |
| Duan, WB; He, F; Jiang, W; Li, S; Luo, T; Shen, XY; Wang, HQ; Xu, J; Zhou, Y | 1 |
| Guo, X; Jiang, Y; Ma, X; Tu, P; Wang, W; Zhao, M | 1 |
| Li, S; Luo, T; Mai, QA; Ouyang, T; Shen, XY; Wang, HQ | 1 |
| Ma, S; She, L; Tian, X; Yan, S; Yang, W; Yu, K; Zhang, X | 1 |
| Jin, DY; Lou, WH; Rong, YF; Wu, W; Xu, XF; Zhang, L | 1 |
| Chen, C; Lian, W; Liu, S; Shi, L; Su, R; Wan, D; Wang, Y; Xu, N; Yang, H; Yao, W | 1 |
| Chatterjee, S; Suresh Kumar, G | 1 |
| Cong, H; Deng, S; Huo, X; Sun, C; Wang, C; Wang, Y; Wu, B; Xiang, T; Zhang, B; Zhang, H; Zhang, L; Zhao, X; Zheng, L | 1 |
| Gao, YG; He, ZM; Li, GF; Yang, H; Zhang, LX; Zhao, Y; Zheng, JY; Zhu, HY | 1 |
| Chen, YS; Huang, CC; Lee, IJ; Li, LA; Lo, SN; Ueng, YF; Wang, CW; Wu, TS | 1 |
| Tan, W; Yi, L; Yuan, G; Zhang, L; Zhou, J; Zhu, Z | 1 |
| Jiang, Y; Li, HJ; Li, P; Lu, J; Ni, H; Wu, TJ | 1 |
| Chen, G; Cui, C; Li, H; Liu, M; Liu, Z; Ma, X; Qiu, H; Sun, S | 1 |
| Clift, MD; De Los Santos, AR; Hedrick, SL; Mori-Quiroz, LM | 1 |
| Chen, G; Li, H; Liu, M; Liu, X; Ma, X; Qiu, H; Sun, Q; Sun, S; Wang, J; Xu, L | 1 |
| Jiang, H; Lei, S; Sun, S; Wang, K; Zhou, H; Zhou, S; Zhu, S | 1 |
| Bandyopadhyay, S; Bhattacharyya, R; Chattopadhyay, S; Gupta, P; Patro, BS | 1 |
| DU, H; Fan, G; Lai, XR; Li, Q; Wang, YJ; Wen, HS; Xu, T | 1 |
| Dian, L; Gao, X; Li, J; Liang, Z; Sun, Y; Wink, M; Wu, P | 1 |
| Cui, WF; Ge, WJ; Li, GS; Liang, RF; Song, XM; Zhang, JP; Zhang, SF | 1 |
| Dian, LL; Gao, XY; Liang, ZS; Phyo, AT; Qasim, M; Sun, YF; Sun, ZX; Wang, P; Yang, SQ | 1 |
| Huang, XL; Liang, H; Qin, QP; Tan, MX; Wang, SL; Wang, ZF; Zhang, Y; Zou, BQ | 1 |
| Huang, XL; Liang, H; Luo, ZH; Qin, QP; Tan, MX; Wang, SL; Wang, ZF; Zou, BQ | 1 |
| Kamimura, S; Nishihara, M; Osumi, Y; Shiota, H | 1 |
| Jiang, W; Luo, T; Ouyang, T; Qu, YH; Shen, XY; Wang, F; Wang, HQ; Wang, S; Zhang, M | 1 |
| Chu, C; Jiang, L; Li, J; Lian, L; Liu, C; Mao, H; Yan, J | 1 |
| Hu, J; Liu, W; Lu, K; Lu, Z; Ma, B; Wang, Y; Wei, W; Wen, D | 1 |
| Chen, X; Mu, T; Wu, G; Zhang, L | 1 |
| Chen, H; Liu, L; Wang, N; Wang, X; Yang, T | 1 |
| Dodoala, S; Hema, K; Koganti, B; M, P; Reddy, GJ | 1 |
| Alolga, RN; Asante, DO; Boucetta, H; Kok-Fong, LL; Rolle, J; Seidu, TA; Tai, LLK | 1 |
| An, L; Deng, J; He, H; Li, X; Yang, M; Ye, X | 1 |
| Hong, T; Li, J; Pan, X; Wen, L; Xia, M; Xu, H; Zheng, Z | 1 |
3 review(s) available for berberine and jatrorrhizine
| Article | Year |
|---|---|
Annual review of LSD1/KDM1A inhibitors in 2020.
Topics: Antineoplastic Agents, Phytogenic; Enzyme Inhibitors; Histone Demethylases; Humans; Molecular Structure; Neoplasms | 2021 |
Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: binding aspects and implications for drug design.
Topics: Alkaloids; Animals; Benzophenanthridines; Berberine; Berberine Alkaloids; Calorimetry; Chemistry, Pharmaceutical; DNA; Drug Design; Humans; Isoquinolines; Mice; Models, Chemical; Nucleic Acids; RNA; Spectrophotometry; Temperature | 2011 |
Jatrorrhizine: a review of its pharmacological effects.
Topics: Animals; Berberine; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Plants, Medicinal | 2021 |
1 trial(s) available for berberine and jatrorrhizine
| Article | Year |
|---|---|
Identification of three sulfate-conjugated metabolites of berberine chloride in healthy volunteers' urine after oral administration.
Topics: Adult; Antidiarrheals; Berberine; Humans; Magnetic Resonance Spectroscopy; Male; Spectrometry, Mass, Electrospray Ionization; Sulfates | 2002 |
126 other study(ies) available for berberine and jatrorrhizine
| Article | Year |
|---|---|
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites | 2011 |
Neuraminidase inhibitory activities of quaternary isoquinoline alkaloids from Corydalis turtschaninovii rhizome.
Topics: Alkaloids; Anti-Bacterial Agents; Clostridium Infections; Clostridium perfringens; Corydalis; Enzyme Inhibitors; Humans; Isoquinolines; Molecular Docking Simulation; Neuraminidase; Rhizome | 2014 |
Isoquinoline alkaloids from Coptis japonica stimulate the myoblast differentiation via p38 MAP-kinase and Akt signaling pathway.
Topics: Alkaloids; Animals; Cell Differentiation; Cell Line; Coptis; Mice; Myoblasts | 2017 |
Two new 8-oxotetrahydroprotoberberine alkaloids, gusanlung A and B, from Acangelisia gusanlung.
Topics: Berberine; Drugs, Chinese Herbal; Molecular Structure | 1991 |
[Chemical constituents of Asteropyrum peltatum (Franch.) Drumm. et Hutch].
Topics: Berberine; Berberine Alkaloids; Drugs, Chinese Herbal | 1990 |
[Extraction and isolation of jatrorrhizine choride in the preparation of berberine chloride].
Topics: Berberine; Berberine Alkaloids; Drugs, Chinese Herbal | 1989 |
[Quantitative determination of 5 alkaloids in plants of Coptis from China].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, Thin Layer; Densitometry; Drugs, Chinese Herbal; Triterpenes | 1989 |
[The blocking and partial agonistic actions of jatrorrhizine on alpha-adrenoceptors].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Berberine; Berberine Alkaloids; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Male; Muscle Contraction; Rabbits; Rats; Rats, Inbred Strains; Vas Deferens | 1989 |
Protoberberine alkaloids as antimalarials.
Topics: Animals; Antimalarials; Berberine; Berberine Alkaloids; Plasmodium falciparum | 1988 |
Natural protoberberine alkaloids from Enantia chlorantha, palmatine, columbamine and jatrorrhizine for thioacetamide-traumatized rat liver.
Topics: Acetamides; Animals; Berberine; Berberine Alkaloids; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Liver; Male; Plants; Rats; Rats, Inbred Strains; Thioacetamide | 1988 |
Isolation of jatrorrhizine from Tinospora cordifolia roots.
Topics: Berberine; Plants, Medicinal | 1995 |
[Study on active constituents of traditional Chinese medicine reversing multidrug resistance of tumor cells in vitro].
Topics: Antineoplastic Agents, Phytogenic; Berberine; Curcumin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Indoles; Tumor Cells, Cultured; Vincristine | 2001 |
Effect of Mahonia aquifolium active compounds on interleukin-8 production in the human monocytic cell line THP-1.
Topics: Alkaloids; Benzylisoquinolines; Berberine; Humans; Interleukin-8; Isoquinolines; Mahonia; Molecular Structure; Plant Bark; Plant Extracts; Plant Stems; Tumor Cells, Cultured | 2002 |
Potential antimutagenic activity of berberine, a constituent of Mahonia aquifolium.
Topics: Animals; Antimutagenic Agents; Berberine; Dose-Response Relationship, Drug; Euglena gracilis; Mahonia; Phytotherapy; Plant Bark; Plant Extracts | 2002 |
[Determination of alkaloids in Coptis-Cinnamomum compatibility by capillary electrophoresis].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Cinnamomum; Coptis; Drug Combinations; Drugs, Chinese Herbal; Electrophoresis, Capillary; Plants, Medicinal | 1999 |
High-performance capillary electrophoresis for determining the contents of berberine, jatrorrhizine and palmatine in Gegenqinlian decoction.
Topics: Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Electrophoresis, Capillary; Medicine, Chinese Traditional | 2003 |
[Study on the solubility changes of Rhizoma Coptidis' main chemical constituents influenced by the proportion of Rhizoma Coptidis and Fructus Evodiae].
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drug Combinations; Drugs, Chinese Herbal; Evodia; Plant Roots; Plants, Medicinal; Solubility | 2003 |
Oxygen activation by photoexcited protoberberinium alkaloids from Mahonia aquifolium.
Topics: Berberine; Berberine Alkaloids; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Mahonia; Photochemistry; Photosensitizing Agents; Phytotherapy; Plant Extracts | 2004 |
Antimicrobial activity of Mahonia aquifolium crude extract and its major isolated alkaloids.
Topics: Anti-Infective Agents; Berberine; Berberine Alkaloids; Candida; Humans; Mahonia; Microbial Sensitivity Tests; Phytotherapy; Plant Extracts; Plant Stems; Propionibacterium acnes; Staphylococcus | 2004 |
Structural elucidation and identification of alkaloids in Rhizoma Coptidis by electrospray ionization tandem mass spectrometry.
Topics: Berberine; Berberine Alkaloids; Coptis; Drugs, Chinese Herbal; Plant Roots; Spectrometry, Mass, Electrospray Ionization | 2004 |
[Determination of four alkaloids in Berberis plants by HPLC].
Topics: Alkaloids; Benzylisoquinolines; Berberine; Berberine Alkaloids; Berberis; China; Chromatography, High Pressure Liquid; Ecosystem; Plant Bark; Plant Roots; Plant Stems; Plants, Medicinal; Species Specificity | 2003 |
[Establishment of the control substance of plant drug and fingerprints of Coptis chinensis].
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Magnetic Resonance Spectroscopy; Plants, Medicinal; Quality Control | 2004 |
Analysis of protoberberine alkaloids in several herbal drugs and related medicinal preparations by non-aqueous capillary electrophoresis.
Topics: Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Electrophoresis, Capillary; Plants, Medicinal; Reproducibility of Results | 2005 |
Binding of the bioactive component jatrorrhizine to human serum albumin.
Topics: Berberine; Binding Sites; Circular Dichroism; Humans; Ions; Models, Molecular; Molecular Structure; Plant Extracts; Protein Binding; Protein Structure, Secondary; Serum Albumin | 2005 |
[Quality assessment of Coptis chinensis in China].
Topics: Alkaloids; Berberine; Berberine Alkaloids; China; Chromatography, High Pressure Liquid; Coptis; Ecosystem; Plants, Medicinal; Quality Control; Spectrophotometry, Ultraviolet | 2005 |
Capillary electrochromatography with a neutral monolithic column for classification of analytes and determination of basic drugs in human serum.
Topics: Atenolol; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Humans; Methacrylates; Metoprolol; Reproducibility of Results; Sensitivity and Specificity; Silanes | 2005 |
[Chemical constituents from Corydalis humosa].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, Thin Layer; Corydalis; Ethanol; Plants, Medicinal; Rhizome; Spectrophotometry, Infrared | 2005 |
Hypoglycemic activity of jatrorrhizine.
Topics: Animals; Berberine; Diabetes Mellitus, Experimental; Glycolysis; Hypoglycemic Agents; L-Lactate Dehydrogenase; Lactic Acid; Liver Glycogen; Male; Mice; Platelet Aggregation Inhibitors; Rabbits; Succinate Dehydrogenase | 2005 |
Spacer length and attaching position-dependent binding of synthesized protoberberine dimers to double-stranded DNA.
Topics: Berberine; Berberine Alkaloids; Dimerization; DNA | 2006 |
Nonaqueous capillary electrophoresis coupled with laser-induced native fluorescence detection for the analysis of berberine, palmatine, and jatrorrhizine in Chinese herbal medicines.
Topics: Acetates; Acetic Acid; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Electrophoresis, Capillary; Lasers; Medicine, Chinese Traditional; Molecular Structure; Plant Extracts; Plants, Medicinal; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2006 |
[Qualitative and quantitative determination of the main components of huanglianjiedu decoction by HPLC-UV/MS].
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Gardenia; Mass Spectrometry; Phellodendron; Plants, Medicinal; Quality Control; Scutellaria baicalensis; Spectrophotometry, Ultraviolet | 2006 |
Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry.
Topics: Animals; Bacteria; Berberine; Bile; Chromatography, Liquid; Germ-Free Life; Intestinal Absorption; Intestine, Small; Liver; Male; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2006 |
[Liquid chromatography-tandem electrospray ionization ion trap mass spectrometric assay for the metabolites of jatrorrhizine in rat urine].
Topics: Animals; Berberine; Chromatography, High Pressure Liquid; Coptis; Molecular Structure; Plants, Medicinal; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization | 2006 |
[Quality analysis and evaluation of Rhizoma Coptidis under different cultivation conditions].
Topics: Berberine; Berberine Alkaloids; China; Chromatography, High Pressure Liquid; Coptis; Ecosystem; Plants, Medicinal; Quality Control; Reference Standards; Reproducibility of Results; Rhizome; Spectrometry, Mass, Electrospray Ionization | 2006 |
[Determination of 3 kinds of components in huanglian jiedu decoction by HPLC under different UV wavelengths].
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Flavonoids; Iridoids; Plants, Medicinal; Pyrans; Quality Control; Ultraviolet Rays | 2006 |
High performance liquid chromatography-mass spectrometry analysis of protoberberine alkaloids in medicine herbs.
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis chinensis; Drugs, Chinese Herbal; Mass Spectrometry; Molecular Structure; Phellodendron | 2007 |
Studies on alkaloids binding to GC-rich human survivin promoter DNA using positive and negative ion electrospray ionization mass spectrometry.
Topics: Alkaloids; Antineoplastic Agents; Base Composition; Benzylisoquinolines; Berberine; Berberine Alkaloids; DNA; GC Rich Sequence; Humans; Inhibitor of Apoptosis Proteins; Intercalating Agents; Microtubule-Associated Proteins; Molecular Structure; Neoplasm Proteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Reserpine; Spectrometry, Mass, Electrospray Ionization; Survivin; Tandem Mass Spectrometry | 2008 |
Simultaneous determination of berberine, palmatine and jatrorrhizine by liquid chromatography-tandem mass spectrometry in rat plasma and its application in a pharmacokinetic study after oral administration of coptis-evodia herb couple.
Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Evodia; Male; Molecular Structure; Plant Preparations; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Synthesis and antimicrobial activity of 3-alkoxyjatrorrhizine derivatives.
Topics: Anti-Infective Agents; Berberine; Coptis; Drugs, Chinese Herbal; Microbial Sensitivity Tests; Toxicity Tests | 2008 |
[Analysis of the main components of coptis-evodia herb couple by HPLC-DAD-MS].
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Evodia; Plant Extracts; Spectrometry, Mass, Electrospray Ionization | 2008 |
LC/MS/MS for identification of in vivo and in vitro metabolites of jatrorrhizine.
Topics: Animals; Berberine; Chromatography, High Pressure Liquid; Feces; Microsomes, Liver; Rats; Rats, Wistar; Reproducibility of Results; Tandem Mass Spectrometry | 2008 |
[Variation patterns of Coptis teeta biomass and its major active compounds along an altitude gradient].
Topics: Altitude; Berberine; Biomass; China; Coptis; Ecosystem; Plant Roots; Rhizome | 2008 |
Synthesis and antimicrobial activity of 3-octyloxy-8-alkyljatrorrhizine derivatives.
Topics: Bacteria; Berberine; Candida tropicalis; Drugs, Chinese Herbal; Microbial Sensitivity Tests; Molecular Structure; Ranunculaceae | 2009 |
[Effect of additives on absorption of Coptis chinensis total alkaloids and pharmacokinetics in mice].
Topics: Absorption; Alkaloids; Animals; Berberine; Chromatography, High Pressure Liquid; Coptis; Diterpenes; Drug Interactions; Female; Food Additives; Half-Life; Male; Mice | 2009 |
[Pharmacokinetics of three alkaloids in Huanglianjiedu decoction in rat serum by LC-MS-MS].
Topics: Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Male; Quality Control; Rats; Rats, Sprague-Dawley; Reference Standards; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
[Effects of extracts and active components of Rhizoma Coptidis on contraction of circular smooth muscle isolated from guinea pig gastric antrum].
Topics: Animals; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Guinea Pigs; Muscle, Smooth; Plant Extracts; Pyloric Antrum | 2009 |
Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells.
Topics: Animals; Berberine; Berberine Alkaloids; Cells, Cultured; Drugs, Chinese Herbal; E-Selectin; Endothelium, Vascular; Esculin; Furans; Interleukin-6; Interleukin-8; Intestinal Mucosa; Lipopolysaccharides; Rats; Thromboxane B2; Umbelliferones | 2009 |
The application of digital image recognition to the analysis of two-dimensional fingerprints.
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Cluster Analysis; Drugs, Chinese Herbal; Signal Processing, Computer-Assisted | 2010 |
Rhizoma coptidis and berberine-induced activation of murine microglia N9 cells.
Topics: Animals; Berberine; Berberine Alkaloids; Calcium; Coptis; DNA, Complementary; Dose-Response Relationship, Drug; Enzymes; Flow Cytometry; Gene Expression; Gene Expression Regulation; Genes; Membrane Potential, Mitochondrial; Mice; Microglia; Phagocytosis; Plant Extracts; Reactive Oxygen Species; Rhizome; Up-Regulation | 2010 |
[Preliminary study to investigate dynamic extract process of Huanglian Jiedu Tang and the mechanism of subsidence produce].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavones; Flavonoids; Fractional Precipitation; Iridoids; Plants, Medicinal | 2010 |
Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese
Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Chromatography, Liquid; Coptis; Flavanones; Flavonoids; Male; Medicine, Chinese Traditional; Rats; Rats, Sprague-Dawley; Scutellaria; Tandem Mass Spectrometry | 2010 |
[In situ intestinal absorption kinetics of berberine and jatrorrhizine from extractive Rhizoma Coptidis in rats].
Topics: Animals; Berberine; Coptis chinensis; Drugs, Chinese Herbal; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Rats; Rats, Wistar; Rhizome | 2010 |
[Simultaneous determination of the five alkaloids in Rhizoma Coptidis by nonaqueous capillary electrophoresis].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Coptis chinensis; Drugs, Chinese Herbal; Electrophoresis, Capillary | 2010 |
[Simultaneous determination of jatrorrhizine, palmatine, berberine, and obacunone in Phellodendri Amurensis Cortex by RP-HPLC].
Topics: Benzoxepins; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Limonins; Phellodendron | 2010 |
Intestinal absorption mechanisms of berberine, palmatine, jateorhizine, and coptisine: involvement of P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Berberine Alkaloids; Biological Transport; Caco-2 Cells; Cyclosporine; Drugs, Chinese Herbal; Humans; Intestinal Absorption; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Propionates; Quinolines; Verapamil | 2011 |
Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes.
Topics: AMP-Activated Protein Kinases; Animals; Berberine; Biotransformation; Cytochrome P-450 Enzyme System; Hep G2 Cells; Humans; Isoenzymes; Liver; Male; Metabolic Detoxication, Phase I; Rats; Rats, Wistar; Receptor, Insulin; Receptors, LDL | 2011 |
The effects of jatrorrhizine on contractile responses of rat ileum.
Topics: Animals; Berberine; Calcium Signaling; Drug Interactions; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Serotonin; Serotonin Antagonists | 2011 |
Neuroprotective effect of Jatrorrhizine on hydrogen peroxide-induced cell injury and its potential mechanisms in PC12 cells.
Topics: Animals; Apoptosis; Berberine; Caspase 3; Cell Survival; Dose-Response Relationship, Drug; Heme Oxygenase-1; Hydrogen Peroxide; L-Lactate Dehydrogenase; Malondialdehyde; Membrane Potential, Mitochondrial; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2011 |
Ionic liquid sensitized fluorescence determination of four isoquinoline alkaloids.
Topics: Alkaloids; Berberine; Berberine Alkaloids; Ionic Liquids; Isoquinolines; Temperature | 2011 |
Micelle to solvent stacking of two alkaloids in nonaqueous capillary electrophoresis.
Topics: Alkaloids; Berberine; Electrophoresis, Capillary; Micelles; Sensitivity and Specificity | 2011 |
Determination of berberine, palmatine and jatrorrhizine in rabbit plasma by liquid chromatography-electrospray ionization-mass spectrometry.
Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Calibration; Chromatography, Liquid; Drugs, Chinese Herbal; Limit of Detection; Male; Quality Control; Rabbits; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2011 |
Determination of protoberberine alkaloids in Rhizoma Coptidis by ERETIC ¹H NMR method.
Topics: Berberine; Berberine Alkaloids; Coptis; Limit of Detection; Magnetic Resonance Spectroscopy | 2012 |
Isoquinoline alkaloids from Tinospora cordifolia inhibit rat lens aldose reductase.
Topics: Aldehyde Reductase; Animals; Aporphines; Berberine; Berberine Alkaloids; Enzyme Inhibitors; In Vitro Techniques; Lens, Crystalline; Male; Plant Extracts; Rats; Rats, Wistar; Tinospora | 2012 |
Effect of jatrorrhizine on delayed gastrointestinal transit in rat postoperative ileus.
Topics: Animals; Atropine; Berberine; Cholinergic Fibers; Dose-Response Relationship, Drug; Drug Interactions; Evans Blue; Gastric Emptying; Gastrointestinal Transit; Ileus; Laparotomy; Male; Muscarinic Agonists; Plant Extracts; Plants, Medicinal; Postoperative Complications; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Antagonists; Time Factors | 2012 |
Pharmacokinetics and metabolism of jatrorrhizine, a gastric prokinetic drug candidate.
Topics: Animals; Area Under Curve; Berberine; Cytochrome P-450 Enzyme System; Female; Gastrointestinal Agents; Glucuronosyltransferase; Half-Life; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 2012 |
[Distribution of four alkaloids in plants of Berberis].
Topics: Benzylisoquinolines; Berberine; Berberine Alkaloids; Berberis; China; Chromatography, High Pressure Liquid; Plant Bark; Plant Roots; Plant Stems; Plants, Medicinal; Reproducibility of Results; Seasons | 2004 |
Analysis of four alkaloids of Coptis chinensis in rat plasma by high performance liquid chromatography with electrochemical detection.
Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Calibration; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Coptis; Coptis chinensis; Drugs, Chinese Herbal; Electrochemical Techniques; Electrodes; Limit of Detection; Rats | 2012 |
Discrimination of Phellodendron amurense and P. chinense based on DNA analysis and the simultaneous analysis of alkaloids.
Topics: Alkaloids; Base Sequence; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; DNA, Intergenic; DNA, Plant; Drugs, Chinese Herbal; Limit of Detection; Molecular Sequence Data; Phellodendron; Plant Bark; Plants, Medicinal; Quality Control; Random Amplified Polymorphic DNA Technique; Reproducibility of Results; Ribulose-Bisphosphate Carboxylase | 2012 |
Quality evaluation and species differentiation of Rhizoma coptidis by using proton nuclear magnetic resonance spectroscopy.
Topics: Berberine; Berberine Alkaloids; Coptis; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Multivariate Analysis; Plant Extracts; Principal Component Analysis; Rhizome; Species Specificity | 2012 |
Development and validation of liquid chromatography-tandem mass spectrometry method for simultaneous determination of four tertiary alkaloids in rat plasma and its application to a pharmacokinetic study.
Topics: Acetonitriles; Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, Liquid; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2013 |
The protective effects of jatrorrhizine on β-amyloid (25-35)-induced neurotoxicity in rat cortical neurons.
Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Berberine; Cell Survival; Cells, Cultured; Cerebral Cortex; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2012 |
Involvement of rat organic cation transporter 2 in the renal uptake of jatrorrhizine.
Topics: Animals; Berberine; Biological Transport, Active; Cell Line; Coptis; Corticosterone; Dogs; Female; Kidney; Male; Organic Cation Transport Proteins; Organic Cation Transporter 2; Rats; Rats, Sprague-Dawley | 2013 |
CYP450 1A2 and multiple UGT1A isoforms are responsible for jatrorrhizine metabolism in human liver microsomes.
Topics: Berberine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Gastrointestinal Agents; Glucuronides; Glucuronosyltransferase; Humans; Microsomes, Liver; Protein Isoforms; Recombinant Proteins | 2013 |
[Simultaneous determination of nine effective components in jiaweizuojin pills by ultra performance liquid chromatography with tandem mass spectrometry].
Topics: Benzoates; Berberine; Berberine Alkaloids; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Monoterpenes; Tandem Mass Spectrometry | 2012 |
[Intestinal absorption of different combinations of active compounds from Gegenqinlian decoction by rat single pass intestinal perfusion in situ].
Topics: Animals; Berberine; Berberine Alkaloids; Coptis; Drug Combinations; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glycyrrhiza; Intestinal Absorption; Intestinal Mucosa; Isoflavones; Male; Plant Roots; Plants, Medicinal; Pueraria; Rats; Rats, Sprague-Dawley; Rhizome; Scutellaria baicalensis | 2012 |
[Simultaneous determination of five alkaloids in Niuhuang Shangqing Tablets by micellar electrokinetic chromatography-mass spectrometry using laurel acyl malic acid ester].
Topics: Alkaloids; Berberine; Chromatography, Micellar Electrokinetic Capillary; Drugs, Chinese Herbal; Esters; Malates; Mass Spectrometry; Tablets | 2012 |
Biophysical studies on the interactions of jatrorrhizine with bovine serum albumin by spectroscopic and molecular modeling methods.
Topics: Berberine; Binding Sites; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Conformation; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrum Analysis; Thermodynamics | 2013 |
Jatrorrhizine hydrochloride inhibits the proliferation and neovascularization of C8161 metastatic melanoma cells.
Topics: Animals; Berberine; Cell Line, Tumor; Growth Inhibitors; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic | 2013 |
Inhibition of CYP1 by berberine, palmatine, and jatrorrhizine: selectivity, kinetic characterization, and molecular modeling.
Topics: Aryl Hydrocarbon Hydroxylases; Berberine; Berberine Alkaloids; Computer Simulation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Humans; Models, Molecular; Structural Homology, Protein | 2013 |
Exploring the site-selective binding of jatrorrhizine to human serum albumin: spectroscopic and molecular modeling approaches.
Topics: Berberine; Binding Sites; Circular Dichroism; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Serum Albumin; Spectrometry, Fluorescence; Thermodynamics | 2014 |
Spectroscopic analysis and molecular modeling on the interaction of jatrorrhizine with human serum albumin (HSA).
Topics: Berberine; Binding Sites; Energy Transfer; Humans; Kinetics; Models, Molecular; Serum Albumin; Solutions; Spectrometry, Fluorescence; Temperature | 2014 |
[Screening of the active ingredients in natural products by capillary electrophoresis and high performance liquid chromatography-mass spectrometry].
Topics: Acetylcholinesterase; Alkaloids; Berberine; Berberine Alkaloids; Biological Products; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Electrophoresis, Capillary; Tandem Mass Spectrometry | 2013 |
Tissue distribution of berberine and its metabolites after oral administration in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Berberine; Chromatography, Liquid; Humans; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tissue Distribution | 2013 |
Berberine metabolites could induce low density lipoprotein receptor up-regulation to exert lipid-lowering effects in human hepatoma cells.
Topics: Berberine; Berberine Alkaloids; Berberis; Carcinoma, Hepatocellular; Coptis; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Hypolipidemic Agents; Lipid Metabolism; Lipoproteins, LDL; Liver Neoplasms; Plant Extracts; Receptors, LDL; RNA, Messenger; Up-Regulation | 2014 |
[Microcalorimetric investigation on the interaction of six alkaloids from rhizoma coptidis].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Coptis; Drug Interactions; Drug Synergism; Plants, Medicinal; Quality Control; Rhizome; Shigella dysenteriae | 2013 |
Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of huang-lian-jie-du-tang decoction.
Topics: Administration, Oral; Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Iridoids; Molecular Structure; Rats; Rats, Sprague-Dawley | 2014 |
Study of the voltammetric behavior of jatrorrhizine and its sensitive determination at electrochemical pretreatment glassy carbon electrode.
Topics: Berberine; Calibration; Carbon; Drugs, Chinese Herbal; Electrochemical Techniques; Electrodes; Hydrogen-Ion Concentration; Molecular Structure; Reproducibility of Results; Tinospora | 2014 |
The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis.
Topics: Animals; Anticholesteremic Agents; Berberine; Bile Acids and Salts; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Coptis chinensis; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Male; Mesocricetus; Mice; Plant Roots; Ranunculaceae; Rats, Sprague-Dawley; Receptors, LDL; Toxicity Tests; Triglycerides | 2014 |
Metabolic profiling analysis of berberine, palmatine, jatrorrhizine, coptisine and epiberberine in zebrafish by ultra-high performance liquid chromatography coupled with LTQ Orbitrap mass spectrometer.
Topics: Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Metabolomics; Models, Animal; Tandem Mass Spectrometry; Zebrafish | 2015 |
[Research on bitter components from Coptis chinensis based on electronic tongue].
Topics: Aporphines; Berberine; Berberine Alkaloids; Biomedical Research; Coptis; Drugs, Chinese Herbal; Electronics; Escherichia coli; Microbial Sensitivity Tests; Reproducibility of Results; Staphylococcus aureus; Taste | 2014 |
Two-stage fractionation of polar alkaloids from Rhizoma coptidis by countercurrent chromatography considering the strategy of reactive extraction.
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chemical Fractionation; Countercurrent Distribution; Drugs, Chinese Herbal; Plants, Medicinal; Ranunculaceae | 2015 |
Novel molecularly imprinted magnetic nanoparticles for the selective extraction of protoberberine alkaloids in herbs and rat plasma.
Topics: Administration, Oral; Adsorption; Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Ferric Compounds; Hydrogen-Ion Concentration; Magnetite Nanoparticles; Nanotechnology; Phellodendron; Plant Bark; Plant Extracts; Polymers; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared | 2015 |
Interaction of six protoberberine alkaloids with human organic cation transporters 1, 2 and 3.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Berberine; Berberine Alkaloids; Cells, Cultured; Chromatography, Liquid; Dogs; Humans; Inhibitory Concentration 50; Madin Darby Canine Kidney Cells; Octamer Transcription Factor-3; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Polymorphism, Genetic; Tandem Mass Spectrometry | 2016 |
Pharmacokinetics of a multicomponent herbal preparation in healthy Chinese and African volunteers.
Topics: Adult; Alkaloids; Aporphines; Asian People; Benzylisoquinolines; Berberine; Berberine Alkaloids; Black People; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Healthy Volunteers; Humans; Male; Middle Aged; Spectrometry, Mass, Electrospray Ionization | 2015 |
Jatrorrhizine Protects Against Okadaic Acid Induced Oxidative Toxicity Through Inhibiting the Mitogen-Activated Protein Kinases Pathways in HT22 Hippocampal Neurons.
Topics: Animals; Antioxidants; Apoptosis; Berberine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hippocampus; MAP Kinase Signaling System; Mice; Mitochondria; Neurons; Neuroprotective Agents; Okadaic Acid; Oxidative Stress | 2015 |
A series of strategies for solving the shortage of reference standards for multi-components determination of traditional Chinese medicine, Mahoniae Caulis as a case.
Topics: Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Mahonia; Quality Control; Reference Standards | 2015 |
The Protective Effect of Jatrorrhizine Against Oxidative Stress in Primary Rat Cortical Neurons.
Topics: Adenosine Triphosphate; Animals; Antioxidants; bcl-2-Associated X Protein; Berberine; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; Glutathione Peroxidase; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 2017 |
Jatrorrhizine hydrochloride attenuates hyperlipidemia in a high-fat diet-induced obesity mouse model.
Topics: Animals; Berberine; Body Weight; Coptis; Diet, High-Fat; Hyperlipidemias; Hypolipidemic Agents; Insulin Resistance; Lipid Metabolism; Lipids; Male; Mice; Mice, Inbred C57BL; Obesity; Triglycerides | 2016 |
SN38 increases IL-8 expression through the MAPK pathways in HCT8 cells.
Topics: Berberine; Camptothecin; Cell Line, Tumor; Cell Survival; Fluorouracil; Humans; Interleukin-8; Irinotecan; Janus Kinase 2; MAP Kinase Signaling System; Phosphorylation; Quinazolines; Up-Regulation | 2017 |
High-throughput screening of triplex DNA binders from complicated samples by 96-well pate format in conjunction with peak area-fading UHPLC-Orbitrap MS.
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; DNA; High-Throughput Screening Assays; Mass Spectrometry; Phellodendron; Reproducibility of Results | 2017 |
Small molecule induced poly(A) single strand to self-structure conformational switching: evidence for the prominent role of H-bonding interactions.
Topics: Berberine; Calorimetry, Differential Scanning; Circular Dichroism; Hydrogen Bonding; Microscopy, Atomic Force; Models, Molecular; Molecular Conformation; Poly A | 2017 |
Comparative pharmacokinetics study of five alkaloids in rat plasma and related compound-herb interactions mechanism after oral administration of Shuanghua Baihe tablets.
Topics: Administration, Oral; Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, Liquid; Drugs, Chinese Herbal; Medicine, Chinese Traditional; Rats; Tablets; Tandem Mass Spectrometry | 2018 |
[Pharmacokinetics and oral bioavailability of palmatine and jatrorrhizine in Huangteng in rats].
Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Biological Availability; Drugs, Chinese Herbal; Rats | 2017 |
Berberine Activates Aryl Hydrocarbon Receptor but Suppresses CYP1A1 Induction through miR-21-3p Stimulation in MCF-7 Breast Cancer Cells.
Topics: Basic Helix-Loop-Helix Transcription Factors; Berberine; Berberine Alkaloids; Breast Neoplasms; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; MicroRNAs; Molecular Structure; Receptors, Aryl Hydrocarbon | 2017 |
Hsa-miR-1587 G-quadruplex formation and dimerization induced by NH
Topics: Ammonia; Berberine; Cations, Monovalent; Circular Dichroism; Dimerization; G-Quadruplexes; Humans; MicroRNAs; Potassium; Sodium; Spectrometry, Mass, Electrospray Ionization | 2018 |
Construction of an optimized method for quality evaluation and species discrimination of Coptidis Rhizoma by ion-pair high performance liquid chromatography combined with response surface methodology.
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Ions; Reference Standards; Rhizome | 2018 |
Jatrorrhizine Hydrochloride Suppresses Proliferation, Migration, and Secretion of Synoviocytes In Vitro and Ameliorates Rat Models of Rheumatoid Arthritis In Vivo.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Berberine; Cell Line; Cell Movement; Cell Proliferation; Cytokines; Female; Humans; Mitogen-Activated Protein Kinase 1; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Synoviocytes; Tumor Necrosis Factor-alpha | 2018 |
A Unified Strategy for the Syntheses of the Isoquinolinium Alkaloids Berberine, Coptisine, and Jatrorrhizine.
Topics: Alkylation; Anti-Bacterial Agents; Berberine; Biological Products; Drug Discovery; Humans; Molecular Structure; Oxidation-Reduction; Quinolinium Compounds; Stereoisomerism | 2018 |
Jatrorrhizine Hydrochloride Suppresses RANKL-Induced Osteoclastogenesis and Protects against Wear Particle-Induced Osteolysis.
Topics: Animals; Berberine; Cells, Cultured; Ice; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; p38 Mitogen-Activated Protein Kinases; Prosthesis Failure; RANK Ligand | 2018 |
Jatrorrhizine reduces 5-HT and NE uptake via inhibition of uptake-2 transporters and produces antidepressant-like action in mice.
Topics: Animals; Antidepressive Agents; Berberine; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Organic Cation Transporter 2; Serotonin; Venlafaxine Hydrochloride | 2019 |
Mechanism of coralyne-mediated DNA photo-nicking process.
Topics: Berberine; Berberine Alkaloids; DNA Cleavage; Light | 2019 |
[Determination of six compounds in Berberidis Cortex and comparative study of its different species].
Topics: Berberine; Berberis; Chromatography, High Pressure Liquid; Phytochemicals; Plant Extracts | 2019 |
Jatrorrhizine inhibits mammary carcinoma cells by targeting TNIK mediated Wnt/β-catenin signalling and epithelial-mesenchymal transition (EMT).
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Gene Knockout Techniques; Humans; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Targeted Therapy; Protein Serine-Threonine Kinases; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2019 |
Involvement of organic anion-transporting polypeptides and organic cation transporter in the hepatic uptake of jatrorrhizine.
Topics: Animals; Berberine; Biological Transport; Cations; HEK293 Cells; Humans; Liver; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Rats | 2020 |
Jatrorrhizine inhibits colorectal carcinoma proliferation and metastasis through Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition.
Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; beta Catenin; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Structure-Activity Relationship; Wnt Signaling Pathway; Wound Healing | 2019 |
High in vitro and in vivo antitumor activities of luminecent platinum(II) complexes with jatrorrhizine derivatives.
Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; Cell Survival; DNA Damage; Fluorescent Dyes; HeLa Cells; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Optical Imaging; Organoplatinum Compounds; Platinum; Telomerase | 2019 |
Two telomerase-targeting Pt(ii) complexes of jatrorrhizine and berberine derivatives induce apoptosis in human bladder tumor cells.
Topics: Antineoplastic Agents; Apoptosis; Berberine; Cell Cycle; Cell Line, Tumor; DNA Damage; Humans; Mitochondria; Organoplatinum Compounds; Telomerase; Urinary Bladder Neoplasms | 2019 |
[Simultaneous Quantitative Analysis of Berberine and Other Alkaloids in Powdered Phellodendron Bark].
Topics: Alkaloids; Berberine; Berberine Alkaloids; China; Chromatography, High Pressure Liquid; Drug Stability; Japan; Phellodendron; Plant Bark; Powder Diffraction; Quality Control | 2019 |
Jatrorrhizine Balances the Gut Microbiota and Reverses Learning and Memory Deficits in APP/PS1 transgenic mice.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Astrocytes; Berberine; DNA, Ribosomal; Gastrointestinal Microbiome; Learning; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plaque, Amyloid | 2019 |
Online preconcentration by electrokinetic supercharging for sensitive determination of berberine and jatrorrhizine in biological samples.
Topics: Animals; Berberine; Electrophoresis, Capillary; Feces; Limit of Detection; Linear Models; Male; Mice; Mice, Inbred C57BL; Reproducibility of Results | 2020 |
Apoptosis Activation in Thyroid Cancer Cells by Jatrorrhizine-Platinum(II) Complex via Downregulation of PI3K/AKT/Mammalian Target of Rapamycin (mTOR) Pathway.
Topics: Animals; Apoptosis; Autophagy; Berberine; Cell Line, Tumor; Cell Proliferation; China; Female; Humans; Mice; Mice, Nude; Phosphatidylinositol 3-Kinases; Platinum; Proto-Oncogene Proteins c-akt; Signal Transduction; Thyroid Gland; Thyroid Neoplasms; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2020 |
Jatrorrhizine Hydrochloride alleviates tert-butyl hydroperoxide-induced endothelial cell injury through its anti-inflammatory activity and PPAR-γ activation.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Apoptosis; Berberine; Brain; Cell Survival; Cells, Cultured; Cytokines; Endothelial Cells; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Nitric Oxide Synthase Type III; Oxidative Stress; PPAR gamma; Reactive Oxygen Species; tert-Butylhydroperoxide | 2020 |
Ginkgolide-Platinum(II) Complex GPt(II) Exhibits Therapeutic Effect on Depression in Mice via Upregulation of DA and 5-HT Neurotransmitters.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Berberine; Depression; Disease Models, Animal; Dopamine; Drugs, Chinese Herbal; Ginkgolides; Hippocampus; HSP70 Heat-Shock Proteins; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Neuropeptide Y; Neurotransmitter Agents; Organoplatinum Compounds; Serotonin; Stress, Psychological | 2020 |
Unravelling high-affinity binding compounds towards transmembrane protease serine 2 enzyme in treating SARS-CoV-2 infection using molecular modelling and docking studies.
Topics: Antiviral Agents; Benzamidines; Berberine; Binding Sites; COVID-19 Drug Treatment; Diterpenes; Flavanones; Flavonoids; Guanidines; Lactones; Lanosterol; Meloxicam; Models, Molecular; Proanthocyanidins; Protein Binding; SARS-CoV-2; Serine Endopeptidases; Serine Proteinase Inhibitors | 2021 |
Jatrorrhizine from Rhizoma Coptidis exerts an anti-obesity effect in db/db mice.
Topics: Alkaloids; Animals; Antineoplastic Agents; Berberine; Drugs, Chinese Herbal; Lipids; Mice; Mice, Obese; Obesity; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2022 |
Jatrorrhizine inhibits Piezo1 activation and reduces vascular inflammation in endothelial cells.
Topics: Animals; Berberine; Cardiovascular Diseases; Endothelial Cells; Hydrogen Peroxide; Ion Channels; Mice | 2023 |