berberine and isoquinoline

berberine has been researched along with isoquinoline in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's10 (62.50)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Bock, A; Wanner, G; Zenk, MH1
Baek, SJ; Piyanuch, R; Sukhthankar, M; Wandee, G1
Bachelot, F; Beausoleil, E; Carton, R; Chauvignac, C; Coutadeur, S; Désiré, L; Lacombe, S; Lambeng, N; Leblond, B; Oliveira, CD; Pallares, D; Peillon, H; Picard, V; Pognante, L; Schweighoffer, F; Taverne, T1
Morishige, T; Sato, F; Takemura, T; Tamakoshi, M1
Chueh, WH; Lin, JY2
Blažeković, B; Domitrović, R; Jakovac, H; Marchesi, VV1
Darzynkiewicz, Z; Halicka, HD; Li, J; Zhao, H1
Chow, YL; Sato, F1
Jadhav, AS; Reddy, V; Vijaya Anand, R1
Cai, Z; Cao, YB; Gao, Y; Jiang, YY; Ni, TJ; Tan, SL; Tian, SJ; Zang, CX; Zhang, DZ1
Chakrabarti, T; Chowdhury, SR; Jha, T; Kumar, A; Majumder, HK; Mukhopadhyay, S; Sarkar, T1
Dinesh, P; Rasool, M1
Hua, HM; Jiang, CY; Li, BJ; Li, DH; Li, ZL; Lin, B; Lu, JC; Xue, JJ; Zou, DL1
Broersen, K; Cioffi, F; De Pandis, MF; Florio, D; Huy, PDQ; Krupa, P; Li, MS; Marasco, D; Roviello, GN; Vicidomini, C1
Ariga, K; Dall'Acqua, S; Ferrarese, I; Ferri, N; Giovanna Lupo, M; Hill, JP; Kumar Shrestha, L; Lal Swagat Shrestha, R; Maharjan, B; Panighel, G; Payne, DT; Rossi, I; Sharan Shrestha, S; Sut, S1

Other Studies

16 other study(ies) available for berberine and isoquinoline

ArticleYear
Immunocytological localization of two enzymes involved in berberine biosynthesis.
    Planta, 2002, Volume: 216, Issue:1

    Topics: Alkaloids; Benzylisoquinolines; Berberine; Berberine Alkaloids; Berberis; Cells, Cultured; Eschscholzia; Immunohistochemistry; Isoquinolines; Microscopy, Immunoelectron; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Oxidoreductases, N-Demethylating; Papaver; Plant Cells; Plants; Vacuoles

2002
Berberine, a natural isoquinoline alkaloid, induces NAG-1 and ATF3 expression in human colorectal cancer cells.
    Cancer letters, 2007, Dec-18, Volume: 258, Issue:2

    Topics: Activating Transcription Factor 3; Alkaloids; Apoptosis; Berberine; Biological Products; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cytokines; Dose-Response Relationship, Drug; Flow Cytometry; Growth Differentiation Factor 15; HCT116 Cells; Humans; Isoquinolines; Luciferases; Protein Kinase Inhibitors; Recombinant Fusion Proteins; RNA, Small Interfering; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53

2007
Structure-activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding.
    Bioorganic & medicinal chemistry letters, 2009, Oct-01, Volume: 19, Issue:19

    Topics: Amino Acid Sequence; Berberine; Binding Sites; Computer Simulation; Enzyme Inhibitors; Isoquinolines; Nucleotides; Protein Binding; Protein Isoforms; rac1 GTP-Binding Protein; Structure-Activity Relationship

2009
Molecular characterization of O-methyltransferases involved in isoquinoline alkaloid biosynthesis in Coptis japonica.
    Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2010, Volume: 86, Issue:7

    Topics: Alkaloids; Amino Acid Sequence; Berberine; Binding Sites; Biocatalysis; Coptis; DNA, Complementary; Isoquinolines; Methyltransferases; Molecular Sequence Data; S-Adenosylmethionine; Sequence Homology, Amino Acid; Substrate Specificity

2010
Berberine, an isoquinoline alkaloid in herbal plants, protects pancreatic islets and serum lipids in nonobese diabetic mice.
    Journal of agricultural and food chemistry, 2011, Jul-27, Volume: 59, Issue:14

    Topics: Animals; Berberine; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Humans; Hypoglycemic Agents; Islets of Langerhans; Isoquinolines; Lipids; Mice; Mice, Inbred ICR; Mice, Inbred NOD; Plant Extracts; Protective Agents

2011
Resolution of liver fibrosis by isoquinoline alkaloid berberine in CCl₄-intoxicated mice is mediated by suppression of oxidative stress and upregulation of MMP-2 expression.
    Journal of medicinal food, 2013, Volume: 16, Issue:6

    Topics: Animals; Berberine; Carbon Tetrachloride; Hepatic Stellate Cells; Humans; Isoquinolines; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Oxidative Stress; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Up-Regulation

2013
Berberine suppresses gero-conversion from cell cycle arrest to senescence.
    Aging, 2013, Volume: 5, Issue:8

    Topics: Berberine; Biomarkers; Cell Cycle Checkpoints; Cell Line, Tumor; Cellular Senescence; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Isoquinolines; Laser Scanning Cytometry; Mitoxantrone; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Ribosomal Protein S6 Kinases, 90-kDa; Topoisomerase II Inhibitors; TOR Serine-Threonine Kinases; Tumor Cells, Cultured

2013
Screening of isoquinoline alkaloids for potent lipid metabolism modulation with Caenorhabditis elegans.
    Bioscience, biotechnology, and biochemistry, 2013, Volume: 77, Issue:12

    Topics: Alkaloids; AMP-Activated Protein Kinases; Animals; Azo Compounds; Benzophenanthridines; Berberine; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Drug Evaluation, Preclinical; Gene Knockdown Techniques; Isoquinolines; Lipid Metabolism; Oxazines; Phosphorylation; Protein Serine-Threonine Kinases

2013
A room-temperature protocol to access isoquinolines through Ag(I) catalysed annulation of o-(1-alkynyl)arylaldehydes and ketones with NH4OAc: elaboration to berberine and palmatine.
    Organic & biomolecular chemistry, 2015, Mar-28, Volume: 13, Issue:12

    Topics: Acetates; Aldehydes; Berberine; Berberine Alkaloids; Catalysis; Isoquinolines; Ketones; Silver; Temperature

2015
[Derivatization of berberine based on its synergistic antifungal activity with fluconazole against fluconazole-resistant Candida albicans].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:11

    Topics: Antifungal Agents; Berberine; Candida albicans; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Isoquinolines; Microbial Sensitivity Tests

2014
Berberine, an isoquinoline alkaloid, inhibits streptozotocin-induced apoptosis in mouse pancreatic islets through down-regulating Bax/Bcl-2 gene expression ratio.
    Food chemistry, 2012, May-01, Volume: 132, Issue:1

    Topics: Animals; Apoptosis; Berberine; Down-Regulation; Gene Expression; Genes, bcl-2; Islets of Langerhans; Isoquinolines; Male; Mice; Streptozocin

2012
A new bisbenzylisoquinoline alkaloid isolated from Thalictrum foliolosum, as a potent inhibitor of DNA topoisomerase IB of Leishmania donovani.
    Fitoterapia, 2016, Volume: 109

    Topics: Alkaloids; Animals; Antiprotozoal Agents; Berberine; Berberine Alkaloids; Cells, Cultured; DNA Topoisomerases, Type I; Isoquinolines; Leishmania donovani; Macrophages, Peritoneal; Mice, Inbred BALB C; Molecular Structure; Thalictrum; Topoisomerase I Inhibitors

2016
Berberine, an isoquinoline alkaloid suppresses TXNIP mediated NLRP3 inflammasome activation in MSU crystal stimulated RAW 264.7 macrophages through the upregulation of Nrf2 transcription factor and alleviates MSU crystal induced inflammation in rats.
    International immunopharmacology, 2017, Volume: 44

    Topics: Alkaloids; Animals; Arthritis, Gouty; Berberine; Carrier Proteins; Female; Inflammation; Isoquinolines; Macrophages; Male; Mice; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Wistar; RAW 264.7 Cells; Thioredoxins; Up-Regulation; Uric Acid

2017
Baicalensines A and B, Two Isoquinoline Alkaloids from the Roots of
    Organic letters, 2020, 10-02, Volume: 22, Issue:19

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Berberine; Caco-2 Cells; HL-60 Cells; Humans; Isoquinolines; Molecular Structure; Plant Roots; Thalictrum

2020
Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation.
    Chemico-biological interactions, 2021, Jan-25, Volume: 334

    Topics: Alkaloids; Amyloid beta-Peptides; Benzophenanthridines; Berberine; Berberine Alkaloids; Humans; Isoquinolines; Molecular Docking Simulation; Neuroprotective Agents; Phenanthridines; Plants; Protein Aggregates

2021
Evaluation of the effects of natural isoquinoline alkaloids on low density lipoprotein receptor (LDLR) and proprotein convertase subtilisin/kexin type 9 (PCSK9) in hepatocytes, as new potential hypocholesterolemic agents.
    Bioorganic chemistry, 2022, Volume: 121

    Topics: Berberine; Cholesterol; Hepatocytes; Isoquinolines; Proprotein Convertase 9; Receptors, LDL; Simvastatin; Subtilisin

2022