berberine and dihydroberberine

berberine has been researched along with dihydroberberine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's0 (0.00)18.2507
2000's2 (10.00)29.6817
2010's12 (60.00)24.3611
2020's5 (25.00)2.80

Authors

AuthorsStudies
Czerniecki, NJ; Douglas, KA; Grundt, P; Krivogorsky, B; Pernat, JA1
KONDO, Y; TAKEMOTO, T1
Dong, XP; Feng, YL; Yu, BY1
Cheng, Z; Cooney, GJ; Gosby, A; Hu, LH; James, DE; Kraegen, EW; Li, J; Li, JY; Miyoshi, H; Taketo, MM; To, SW; Turner, N; Ye, JM1
Chen, AF; Cheng, Z; Gu, M; Hu, LH; Li, J; Li, JY; Li, YY; Sheng, L; Wu, F; Zhang, HK; Zhang, LN1
Donahue, JP; Payton-Stewart, F; Pingali, S1
Dong, S; Wei, SC; Xu, LJ; Zhang, CY1
Chen, G; Dong, H; Huang, ZY; Liu, DL; Lu, FE; Luo, YH; Wang, KF; Xu, LJ; Zou, X1
Chen, X; Chen, Y; Feng, R; Fu, J; He, CY; Huang, M; Jiang, JD; Li, XY; Lin, Y; Ma, C; Ren, G; Shou, JW; Tan, XS; Wang, Y; Wen, BY; Yang, XY; You, XF; Zhao, ZX1
Bianucci, AM; Borghini, A; Pietra, D1
Deng, AJ; Li, J; Li, ZH; Qin, HL; Song, HR; Wang, WJ; Wu, LQ; Zhang, HJ; Zhang, ZH1
Dai, B; Liu, R; Ma, Y; Wang, W; Zhan, Y; Zhang, D; Zhang, Y1
Fang, L; Li, B; Lv, L; Wang, J; Yu, D; Zhan, G; Zhang, B; Zhao, L; Zhao, X1
Azike, CG; Baranowski, DC; Buchanan, B; Gabriele, J; Meng, Q; Poulin, MM; Zuccolo, J1
Ai, G; Chen, H; Chen, J; Li, C; Luo, C; Su, Z; Tan, L; Wang, Y; Xie, J; Zeng, H1
Deng, T; Hu, S; Huang, XA; Li, Y; Ling, Y; Liu, F; Peng, G; Wang, X; Wu, S1
Chang, L; Figeys, D; Li, L; Liu, J; Mayne, J; Ning, Z; Stintzi, A; Ye, Y; Zhang, X1
Cao, X; Cong, L; Fu, J; Gao, TL; Han, P; Jiang, JD; Li, XY; Lin, Y; Ma, SR; Pan, LB; Peng, R; Shou, JW; Tong, Q; Wang, Y; Wen, BY; Yu, H; Yu, JB; Zhang, XF; Zhang, ZW; Zhao, ZX1
Dong, N; Li, C; Lu, Q; Mo, Z; Wu, B; Xie, J1
Falk, M; Lewis, KD1

Other Studies

20 other study(ies) available for berberine and dihydroberberine

ArticleYear
Structure-activity studies of some berberine analogs as inhibitors of Toxoplasma gondii.
    Bioorganic & medicinal chemistry letters, 2012, Apr-15, Volume: 22, Issue:8

    Topics: Antiparasitic Agents; Berberine; Cells, Cultured; Inhibitory Concentration 50; Toxoplasma

2012
[Reactions of protoberberine-type alkaloids. I. Reaction of dihydroberberine with alkylhalide].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1962, Volume: 82

    Topics: Alkaloids; Berberine; Berberine Alkaloids; Halogens

1962
[Simultaneous determination of three kinds of components in sanhuang tablets by high-performance liquid chromatography].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:3

    Topics: Anthraquinones; Berberine; Chromatography, High Pressure Liquid; Coptis; Drug Combinations; Drugs, Chinese Herbal; Emodin; Flavanones; Flavonoids; Plants, Medicinal; Quality Control; Reproducibility of Results; Rheum; Scutellaria baicalensis; Tablets

2006
Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action.
    Diabetes, 2008, Volume: 57, Issue:5

    Topics: Adenylate Kinase; Animals; Berberine; Cyclic Nucleotide-Regulated Protein Kinases; Electron Transport Complex I; Enzyme Activation; Insulin; Male; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Phosphorylation; Rats; Rats, Wistar

2008
8,8-Dimethyldihydroberberine with improved bioavailability and oral efficacy on obese and diabetic mouse models.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Animals; Berberine; Diabetes Mellitus; Electron Transport; Glucose; Humans; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Mitochondria; Obesity; Rats; Rats, Sprague-Dawley; Solubility

2010
Weak C-H···X (X = O, N) hydrogen bonds in the crystal structure of dihydroberberine.
    Acta crystallographica. Section C, Structural chemistry, 2014, Volume: 70, Issue:Pt 4

    Topics: Berberine; Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular; Solvents

2014
Intestinal absorption of berberine and 8-hydroxy dihydroberberine and their effects on sugar absorption in rat small intestine.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2014, Volume: 34, Issue:2

    Topics: Absorption; Animals; Berberine; Carbohydrate Metabolism; Carbohydrates; Chromatography, High Pressure Liquid; Glucose; Intestinal Absorption; Rats

2014
Inhibition of proprotein convertase subtilisin/kexin type 9: a novel mechanism of berberine and 8-hydroxy dihydroberberine against hyperlipidemia.
    Chinese journal of integrative medicine, 2015, Volume: 21, Issue:2

    Topics: Animals; Apolipoprotein A-I; Apolipoproteins B; Berberine; Hydroxymethylglutaryl CoA Reductases; Hyperlipidemias; Lipids; Liver; Male; Proprotein Convertase 9; Rats, Wistar; Receptors, LDL; Serine Endopeptidases; Sterol Regulatory Element Binding Protein 2

2015
Transforming berberine into its intestine-absorbable form by the gut microbiota.
    Scientific reports, 2015, Jul-15, Volume: 5

    Topics: Administration, Oral; Animals; Bacteria; Bacterial Proteins; Berberine; Binding Sites; Chromatography, High Pressure Liquid; Gastrointestinal Microbiome; Hypoglycemic Agents; Intestinal Absorption; Intestines; Male; Mice; Molecular Docking Simulation; Nitroreductases; Oxidation-Reduction; Rats, Sprague-Dawley; Solubility; Tandem Mass Spectrometry

2015
In vitro studies of antifibrotic and cytoprotective effects elicited by proto-berberine alkaloids in human dermal fibroblasts.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:6

    Topics: Berberine; Berberine Alkaloids; Cell Proliferation; Cells, Cultured; Collagen; Cytoprotection; Fibroblasts; Fibrosis; Free Radicals; Humans; Hydrogen Peroxide; Interleukin-1beta; Interleukin-6; Mitochondria; Oxidoreductases; Protective Agents; Transforming Growth Factor beta1

2015
Versatile methods for synthesizing organic acid salts of quaternary berberine-type alkaloids as anti-ulcerative colitis agents.
    Journal of Asian natural products research, 2016, Volume: 18, Issue:6

    Topics: Berberine; Colitis, Ulcerative; Hydrastis; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Regulatory Factor X Transcription Factors; Salts

2016
Dihydroberberine exhibits synergistic effects with sunitinib on NSCLC NCI-H460 cells by repressing MAP kinase pathways and inflammatory mediators.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:10

    Topics: A549 Cells; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Berberine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Indoles; Inflammation Mediators; Lung Neoplasms; MAP Kinase Signaling System; Mice, Inbred NOD; Mice, SCID; Pyrroles; Sunitinib; Tumor Burden; Xenograft Model Antitumor Assays

2017
Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Action Potentials; Activating Transcription Factor 6; Berberine; Calnexin; Calreticulin; Drug Design; Ether-A-Go-Go Potassium Channels; Gene Expression Regulation; HEK293 Cells; HSP90 Heat-Shock Proteins; Humans; Patch-Clamp Techniques; Phenylalanine; Protein Folding; Protein Transport; Tyrosine; Unfolded Protein Response

2017
Comparative pharmacokinetics and safety assessment of transdermal berberine and dihydroberberine.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Berberine; Calibration; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Half-Life; Kidney; Limit of Detection; Liver; Male; Rats; Rats, Sprague-Dawley; Simvastatin; Tandem Mass Spectrometry

2018
Dihydroberberine, a hydrogenated derivative of berberine firstly identified in Phellodendri Chinese Cortex, exerts anti-inflammatory effect via dual modulation of NF-κB and MAPK signaling pathways.
    International immunopharmacology, 2019, Volume: 75

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Berberine; Capillary Permeability; Carrageenan; Cytokines; Edema; Female; Foot; Male; MAP Kinase Signaling System; Mice; NF-kappa B; Phellodendron; Plant Bark; Xylenes

2019
A new fluorescent probe for sensing of biothiols and screening of acetylcholinesterase inhibitors.
    Organic & biomolecular chemistry, 2020, 04-01, Volume: 18, Issue:13

    Topics: Acetylcholinesterase; Animals; Berberine; Boron Compounds; Cholinesterase Inhibitors; Drug Evaluation, Preclinical; Elasmobranchii; Electric Fish; Fluorescent Dyes; Glutathione; Limit of Detection; Molecular Docking Simulation; Protein Binding; Styrenes; Tacrine

2020
Berberine and its structural analogs have differing effects on functional profiles of individual gut microbiomes.
    Gut microbes, 2020, 09-02, Volume: 11, Issue:5

    Topics: Bacterial Proteins; Bacteroidetes; Berberine; Biological Variation, Population; Butyrates; Firmicutes; Gastrointestinal Microbiome; Humans; Metabolic Networks and Pathways; Molecular Structure; Proteobacteria; Proteomics; Verrucomicrobia

2020
Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson's disease by regulating gut microbiota.
    Signal transduction and targeted therapy, 2021, 02-24, Volume: 6, Issue:1

    Topics: Animals; Berberine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Enterococcus faecalis; Enterococcus faecium; Gastrointestinal Microbiome; Humans; Levodopa; Mice; Parkinson Disease; Tyrosine 3-Monooxygenase

2021
Dihydroberberine, an isoquinoline alkaloid, exhibits protective effect against dextran sulfate sodium-induced ulcerative colitis in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 90

    Topics: Animals; Berberine; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Isoquinolines; Mice; Myeloid Differentiation Factor 88; NF-kappa B; Phytochemicals; Protective Agents; Signal Transduction; Toll-Like Receptor 4

2021
Toxicological assessment of dihydroberberine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 168

    Topics: Animals; Berberine; Female; Lethal Dose 50; Male; Mice; Micronucleus Tests; No-Observed-Adverse-Effect Level; Rats; Rats, Sprague-Dawley

2022