berberine and curcumin

berberine has been researched along with curcumin in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19905 (6.33)18.7374
1990's0 (0.00)18.2507
2000's9 (11.39)29.6817
2010's40 (50.63)24.3611
2020's25 (31.65)2.80

Authors

AuthorsStudies
Sashidhara, KV; Singh, SP1
Atanasov, AG; Kamal, MA; Khan, H; Nabavi, SM; Pervaiz, A; Rengasamy, KRR1
Alharthi, S; Moyle, PM; Ziora, ZM1
Liu, S; Ren, L; Yang, L; Zhang, H1
Hur, GM; Kim, YH; Lee, CJ; Lee, JH; Park, YC; Seok, JH; Seol, IC1
Koizumi, K; Matsuo, M; Saiki, I; Sakurai, H1
Harikumar, KB; Kuttan, G; Kuttan, R1
Efferth, T; Hoheisel, JD; Youns, M1
Weng, J; Xia, X1
Jiang, W; Kou, J; Sun, L; Yu, B; Yuan, S1
Kim, MH; Kim, SH; Yang, WM1
Chen, CY; Li, WC; Ting, CT; Tsai, TH1
Balakrishna, A; Kumar, MH1
Srivastava, P; Tiwari, A1
Bharti, AC; Dwivedi, M; Mahata, S; Mehrotra, R; Misra, SP; Misra, V; Pandey, A; Tripathi, SC; Vishnoi, K1
Cicero, AF; Colletti, A1
Allijn, IE; Beukelman, KJ; de Winther, MP; Quarles van Ufford, LC; Schiffelers, RM; Storm, G; Vaessen, SF1
Bao, J; Chen, M; He, C; Jia, X; Li, P; Liang, Y; Su, H; Wan, JB; Wang, K; Wang, X; Zhang, C1
Awasthi, A; Bharate, SS; Gopalakrishna Pillai, GK; Jaggi, M; Mishra, G; Mithal, A; Singh, AT; Verma, R; Vishwakarma, RA1
Bianchi, S; Giovannini, L1
Abrams, SL; Candido, S; Cervello, M; Cocco, L; Gizak, A; Lertpiriyapong, K; Libra, M; Martelli, AM; McCubrey, JA; Montalto, G; Rakus, D; Ratti, S; Steelman, LS1
Calabresi, L; Pavanello, C; Ruscica, M; Sirtori, CR1
Gao, H; Jiang, Y; Turdu, G1
Abrams, SL; Candido, S; Cervello, M; Cocco, L; Gizak, A; Lertpiriyapong, K; Libra, M; Lombardi, P; Martelli, AM; McCubrey, JA; Montalto, G; Murata, RM; Rakus, D; Ratti, S; Rosalen, PL; Steelman, LS1
Gao, Z; Li, Q; Tong, X; Wu, X; Zhao, L; Zhao, X1
Feng, WW; Kuang, SY; Liu, TS; Ma, ZJ; Pang, JY; Tu, C; Wang, JB; Wang, YH; Xiao, XH; Zang, QC; Zhao, YL1
Bianchi, S; Daniele, S; Franzoni, F; Fusi, J; Galetta, F; Giovannini, L; Martini, C; Pellegrini, S1
Bianconi, V; Cosentino, T; Mannarino, MR; Pirro, M; Sahebkar, A1
Chen, C; Geng, C; Hidru, TH; Li, H; Liu, Y; Tao, M; Zhang, Y; Zhi, L; Zou, L1
Bellentani, S; Cicero, AFG; Colletti, A1
Chen, D; Cheng, Z; Fan, X; Fang, L; Hou, X; Wang, Z; Zhang, W1
Dunbar, GL; Maiti, P; Plemmons, A1
Chen, CH; Li, C; Li, M; Lin, L; Yuan, M; Zhang, D1
D'Arcy, MS1
Kaur, A; Kumar, S; Maurya, VK; Mishra, S; Saxena, SK1
Campiglia, P; Carrizzo, A; Ciccarelli, M; Di Pietro, P; Forte, M; Frati, G; Galasso, G; Izzo, C; Rubattu, S; Sciarretta, S; Sommella, E; Vecchione, C; Venturini, E1
Banerjee, R; Bhatia, E; Jadhav, K; Sharma, S1
Dong, C; Gong, X; Jiao, Y; Liu, Y; Meng, Y; Shuang, S; Zhang, H; Zhang, Y1
Bellanti, JA; Boner, AL; Concia, E; Girotto, S; Piazza, M1
Chen, Y; Du, Q; Gong, Z; Huang, J; Jiang, Z; Lu, Y; Peng, J; Shen, X; Sun, R; Xu, J; Zhang, J; Zhou, J1
Akter, R; Bibi, P; Hassan, SSU; Mubin, S; Najda, A; Rahman, MH; Saeeda, S; Shah, M; Wesołowska, S1
Avila-Carrasco, L; Díaz-Avila, DL; García-Mayorga, EA; Garza-Veloz, I; González-Mateo, GT; Martinez-Fierro, ML1
Ghasemi, F; Sahebkar, A; Ziasarabi, P1
Asoodeh, A; Ghobadi-Oghaz, N; Mohammadi, M1
Cao, Y; Chen, X; Gao, Y; Li, X; Li, Y; Luo, L; Tang, G; Tian, Y; Wang, H; Yu, X; Zhou, Z1
Akter, A; Alhumaydhi, FA; Baghayeri, M; Eftekhari, A; Emran, TB; Islam, F; Islam, MM; Islam, MR; Karimi, F; Khan Meem, AF; Khusro, A; Mitra, S; Nafady, MH; Simal-Gandara, J1
Arulmozhi, S; Diddi, S; Lohidasan, S; Mahadik, KR1
Le, TT; Urasaki, Y2
Gupta, P; Lather, V; Mukherjee, M; Nagpal, D; Parmar, VS; Sharma, HK1
Biernaciak, A; Erdmann, J; Janowski, K; Kuźmiński, O; Michalak, K; Nowacka, A; Ohla, J; Szambelan, M; Wiciński, M; Zabrzyński, J1
Kadota, S; Li, H; Miyahara, T; Seto, H; Tezuka, Y; Tran, QL1
NIJLAND, MM; UFFELIE, OF1
HNILICA, L; KLIMEK, M1
HANNA, C; SCHEIN, FT1
MIRZA, R; ROBINSON, R1
Holzgrabe, U; Laug, S; Unger, M1
Joseph, M; Weber, HA1
Bilski, P; Chignell, CF; He, YY; Inbaraj, JJ; Kukielczak, BM; Sik, RH1
Abidi, P; Chen, W; Kraemer, FB; Li, H; Liu, J1
KEENAN, GL1
Douglas, JA; Follett, JM; Littler, RA; Parmenter, GA; Perry, NB; Sansom, CE1
Burns, JT; Cech, NB; Ettefagh, KA; Junio, HA; Kaatz, GW1
Dunnick, JK; Kissling, GE; Nyska, A; Peckham, J; Sanders, JM; Singh, B1
Cech, NB; Cecil, CE; Davis, JM; Laster, SM1
Brettell, T; Dawes, ML1
Ackermann, LW; Cech, NB; Horswill, AR; Junio, HA; Kavanaugh, JS1
Chen, S; Couch, L; Dobrovolsky, VN; Guo, L; Li, Y; Lin, H; Mei, N; Wan, L1
Gurley, BJ; Markowitz, JS; Munoz, J; Wang, X; Zhu, HJ1
Deng, AJ; Li, J; Li, ZH; Qin, HL; Song, HR; Wang, WJ; Wu, LQ; Zhang, HJ; Zhang, ZH1
Backes, JM; Funk, RS; Kandel, SE; Moriarty, PM; Ruisinger, JF; Singh, RK; Winefield, RD1
Britton, ER; Cech, NB; Kellogg, JJ; Kvalheim, OM1
Cui, R; Fan, J; Gao, S; Jin, Y; Li, B; Zhang, K; Zhu, J1
Farjon, J; Giraudeau, P; Le, PM; Martineau, E; Milande, C1
Caesar, LK; Cech, NB; Kellogg, JJ; Khin, M1
Das, N; Devkota, HP; Ishfaq, PM; Maji, AK; Mandal, SK; Mishra, SK; Silva, AS1
Fatima, E; Negi, AS; Pathak, N; Singh, S1
Adiwidjaja, J; Boddy, AV; McLachlan, AJ1
Arian, CM; Calamia, JC; Nguyen, JT; Paine, MF; Rettie, AE; Tanna, RS; Thummel, KE; Tian, DD1

Reviews

25 review(s) available for berberine and curcumin

ArticleYear
Lipid lowering agents of natural origin: An account of some promising chemotypes.
    European journal of medicinal chemistry, 2017, Nov-10, Volume: 140

    Topics: Animals; Biological Products; Dyslipidemias; Humans; Hypolipidemic Agents

2017
Plant-derived mPGES-1 inhibitors or suppressors: A new emerging trend in the search for small molecules to combat inflammation.
    European journal of medicinal chemistry, 2018, Jun-10, Volume: 153

    Topics: Animals; Anti-Inflammatory Agents; Biological Products; Drug Discovery; Enzyme Inhibitors; Humans; Inflammation; Plants, Medicinal; Prostaglandin-E Synthases

2018
Traditional Chinese medicines (TCMs) for molecular targeted therapies of tumours.
    Current drug discovery technologies, 2010, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Arsenic Trioxide; Arsenicals; Artemisinins; Artesunate; Berberine; Biological Products; Cantharidin; Complementary Therapies; Curcumin; Drug Delivery Systems; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Models, Biological; Neoplasms; Oxides

2010
Targeting metabolic syndrome: candidate natural agents.
    Journal of diabetes, 2010, Volume: 2, Issue:4

    Topics: Animals; Anthocyanins; Berberine; China; Curcumin; Female; Flavanones; Genistein; Ginsenosides; Humans; Male; Medicine, Traditional; Metabolic Syndrome; Mice; Momordica charantia; Phytotherapy; Plant Preparations; Prevalence; Randomized Controlled Trials as Topic; Rats; Resveratrol; Stilbenes

2010
Mechanisms of action of phytochemicals from medicinal herbs in the treatment of Alzheimer's disease.
    Planta medica, 2014, Volume: 80, Issue:15

    Topics: Alzheimer Disease; Animals; Berberine; Coptis; Curcuma; Curcumin; Ginsenosides; Humans; Isoflavones; Panax notoginseng; Phytochemicals; Plants, Medicinal; Pueraria; Silybin; Silybum marianum; Silymarin

2014
Preventive and therapeutic role of traditional Chinese herbal medicine in hepatocellular carcinoma.
    Journal of the Chinese Medical Association : JCMA, 2015, Volume: 78, Issue:3

    Topics: Abietanes; Benzylisoquinolines; Berberine; Carcinoma, Hepatocellular; Curcumin; Drugs, Chinese Herbal; Humans; Liver Neoplasms; Medicine, Chinese Traditional; Resveratrol; Scutellaria baicalensis; Stilbenes

2015
A New Insight of Herbal Promises Against Ocular Disorders: An Occuloinformatics Approach.
    Current topics in medicinal chemistry, 2016, Volume: 16, Issue:6

    Topics: Berberine; Computational Biology; Curcumin; Drug Evaluation, Preclinical; Eye Diseases; Ginkgolides; Herbal Medicine; Humans; Inositol; Models, Molecular; Plants, Medicinal

2016
Role of phytochemicals in the management of metabolic syndrome.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Oct-15, Volume: 23, Issue:11

    Topics: Acrolein; Berberine; Catechin; Cinnamates; Curcumin; Diet; Dietary Fiber; Dietary Supplements; Fatty Acids, Omega-3; Flavonols; Humans; Metabolic Syndrome; Phytochemicals; Psyllium

2016
Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases.
    Advances in biological regulation, 2017, Volume: 65

    Topics: Berberine; Cardiovascular Diseases; Curcumin; Gene Expression Regulation; Glycogen Synthase Kinase 3; Humans; Inflammation; Mechanistic Target of Rapamycin Complex 1; Neoplasms; Neurodegenerative Diseases; Osteoarthritis; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Resveratrol; Signal Transduction; Stilbenes

2017
Nutraceutical approaches to metabolic syndrome.
    Annals of medicine, 2017, Volume: 49, Issue:8

    Topics: Berberine; Biological Products; Blood Glucose; Blood Pressure; Curcumin; Dietary Supplements; Female; Humans; Insulin Resistance; Lipoprotein Lipase; Male; Metabolic Syndrome; Plant Proteins, Dietary; Prebiotics; Probiotics; Risk Factors; Vitamin D; Waist Circumference

2017
Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer's disease: A review.
    Bioorganic chemistry, 2017, Volume: 75

    Topics: Acetylcholinesterase; Alzheimer Disease; Berberine; Cholinesterase Inhibitors; Curcumin; Drugs, Chinese Herbal; Flavonoids; Ginsenosides; Humans; Medicine, Chinese Traditional

2017
New Insights into the Mechanisms of Chinese Herbal Products on Diabetes: A Focus on the "Bacteria-Mucosal Immunity-Inflammation-Diabetes" Axis.
    Journal of immunology research, 2017, Volume: 2017

    Topics: Animals; Berberine; Curcumin; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Ginsenosides; Glucose; Humans; Immunity, Mucosal; Inflammation; Momordica charantia; Plant Extracts

2017
Cholesterol-Lowering Nutraceuticals Affecting Vascular Function and Cardiovascular Disease Risk.
    Current cardiology reports, 2018, 05-25, Volume: 20, Issue:7

    Topics: Anticholesteremic Agents; Berberine; Biological Products; Cardiovascular Diseases; Cholesterol; Curcumin; Dietary Fiber; Dietary Supplements; Glycine max; Humans; Phytosterols; Polyphenols

2018
Sonodynamic therapy: A potential treatment for atherosclerosis.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Atherosclerosis; Berberine; Cell Death; Chalcone; Curcumin; Emodin; Humans; Inflammation; Macrophages; Matrix Metalloproteinases; Mice; Neoplasms; Perylene; Photochemotherapy; Plaque, Atherosclerotic; Quinones; Reactive Oxygen Species; THP-1 Cells; Ultrasonic Therapy

2018
Nutraceutical Approach to Non-Alcoholic Fatty Liver Disease (NAFLD): The Available Clinical Evidence.
    Nutrients, 2018, Aug-23, Volume: 10, Issue:9

    Topics: Antioxidants; Berberine; Curcumin; Dietary Supplements; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Humans; Meta-Analysis as Topic; Non-alcoholic Fatty Liver Disease; Obesity; Observational Studies as Topic; Plant Extracts; Probiotics; Randomized Controlled Trials as Topic; Resveratrol; Salvia miltiorrhiza; Silymarin; Ubiquinone; Vitamin D; Vitamin E; Xanthophylls

2018
A review of the chemopreventative and chemotherapeutic properties of the phytochemicals berberine, resveratrol and curcumin, and their influence on cell death via the pathways of apoptosis and autophagy.
    Cell biology international, 2020, Volume: 44, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Berberine; Curcumin; Humans; Neoplasms; Phytochemicals; Resveratrol

2020
Clinical Management and Therapeutic Strategies for the Thyroid-Associated Ophthalmopathy: Current and Future Perspectives.
    Current eye research, 2020, Volume: 45, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antioxidants; Berberine; Curcumin; Graves Ophthalmopathy; Humans; Mydriatics; Proto-Oncogene Mas; Quercetin; Resveratrol; Scopolamine; Withanolides

2020
A Novel Promising Frontier for Human Health: The Beneficial Effects of Nutraceuticals in Cardiovascular Diseases.
    International journal of molecular sciences, 2020, Nov-18, Volume: 21, Issue:22

    Topics: Berberine; Biological Products; Brassica; Cardiovascular Diseases; Curcumin; Dietary Supplements; Health; Quercetin; Resveratrol; Spirulina

2020
Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives.
    Molecules (Basel, Switzerland), 2021, Oct-02, Volume: 26, Issue:19

    Topics: Berberine; Biological Products; Curcumin; Emodin; Genistein; Humans; Neoplasms; Pentacyclic Triterpenes; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy; Resveratrol; Sesquiterpenes; Triterpenes; Ursolic Acid; Vitamin D; Withanolides

2021
Potential Therapeutic Effects of Natural Plant Compounds in Kidney Disease.
    Molecules (Basel, Switzerland), 2021, Oct-09, Volume: 26, Issue:20

    Topics: Antioxidants; Berberine; Beta vulgaris; Betalains; Biological Products; Catechin; Curcumin; Disulfides; Flavonoids; Humans; Isothiocyanates; Kidney; Kidney Diseases; Plant Extracts; Pomegranate; Protective Agents; Resveratrol; Sulfinic Acids; Sulfoxides; Xanthophylls

2021
Multifaceted role of polyphenols in the treatment and management of neurodegenerative diseases.
    Chemosphere, 2022, Volume: 307, Issue:Pt 3

    Topics: Berberine; Curcumin; Genistein; Humans; Luteolin; Neurodegenerative Diseases; Nitrogen; Oxygen; Polyphenols; Quercetin; Resveratrol; Synthetic Drugs

2022
Natural Phytochemicals as SIRT Activators-Focus on Potential Biochemical Mechanisms.
    Nutrients, 2023, Aug-14, Volume: 15, Issue:16

    Topics: Animals; Antioxidants; Berberine; Curcumin; Kaempferols; Mammals; Phytochemicals; Quercetin; Resveratrol; Sirtuin 1

2023
Pharmacological effects of berberine on mood disorders.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:1

    Topics: Animals; Antidepressive Agents; Berberine; Depressive Disorder, Major; Humans; Hydrastis; Mood Disorders; Neuroprotective Agents; Phytotherapy; Plant Preparations

2019
Goldenseal (Hydrastis canadensis L.) and its active constituents: A critical review of their efficacy and toxicological issues.
    Pharmacological research, 2020, Volume: 160

    Topics: Animals; Berberine; Consumer Product Safety; Dietary Supplements; Food Safety; Herb-Drug Interactions; Humans; Hydrastis; Phytochemicals; Plant Extracts; Risk Assessment; Toxicity Tests

2020
Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine.
    European journal of medicinal chemistry, 2021, Dec-15, Volume: 226

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Berberine; Humans; Hydrastis; Hypoglycemic Agents; Molecular Structure

2021

Other Studies

54 other study(ies) available for berberine and curcumin

ArticleYear
Optimized protocols for assessing libraries of poorly soluble sortase A inhibitors for antibacterial activity against medically-relevant bacteria, toxicity and enzyme inhibition.
    Bioorganic & medicinal chemistry, 2021, 12-15, Volume: 52

    Topics: Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Cell Survival; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; HEK293 Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Solubility; Structure-Activity Relationship

2021
[Study on active constituents of traditional Chinese medicine reversing multidrug resistance of tumor cells in vitro].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2001, Volume: 24, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Berberine; Curcumin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Indoles; Tumor Cells, Cultured; Vincristine

2001
Effects of baicalein, berberine, curcumin and hesperidin on mucin release from airway goblet cells.
    Planta medica, 2003, Volume: 69, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Berberine; Cell Line; Coptis; Cricetinae; Curcuma; Curcumin; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Goblet Cells; Hesperidin; Male; Mucins; Phytotherapy; Plants, Medicinal; Poncirus; Scutellaria baicalensis; Trachea

2003
Curcumin inhibits the formation of capillary-like tubes by rat lymphatic endothelial cells.
    Cancer letters, 2007, Jun-28, Volume: 251, Issue:2

    Topics: Animals; Berberine; Capillaries; Cell Adhesion; Cell Line, Tumor; Cell Survival; Curcumin; Dose-Response Relationship, Drug; Endothelial Cells; I-kappa B Kinase; Matrix Metalloproteinase 2; Neoplasm Metastasis; Proto-Oncogene Proteins c-akt; Rats

2007
Inhibition of progression of erythroleukemia induced by Friend virus in BALB/c mice by natural products--berberine, curcumin and picroliv.
    Journal of experimental therapeutics & oncology, 2008, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents; Berberine; Biological Products; Cinnamates; Curcumin; Disease Progression; Friend murine leukemia virus; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glycosides; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Uric Acid; Vanillic Acid

2008
A simplified and high-throughput chromogenic assay for testing tissue factor-dependent procoagulant activity.
    Journal of biomolecular screening, 2011, Volume: 16, Issue:3

    Topics: Berberine; Blood Coagulation Factors; Cells, Cultured; Chromogenic Compounds; Curcumin; Drug Evaluation, Preclinical; Endothelial Cells; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Lipoproteins; Simvastatin; Thromboplastin; Tumor Necrosis Factor-alpha

2011
Evaluation of Synergetic Anticancer Activity of Berberine and Curcumin on Different Models of A549, Hep-G2, MCF-7, Jurkat, and K562 Cell Lines.
    BioMed research international, 2015, Volume: 2015

    Topics: Antineoplastic Combined Chemotherapy Protocols; Berberine; Cell Survival; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Hep G2 Cells; Humans; Jurkat Cells; K562 Cells; MCF-7 Cells; Neoplasms, Experimental; Treatment Outcome

2015
Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil.
    Nutrition and cancer, 2015, Volume: 67, Issue:8

    Topics: Berberine; Cell Line, Tumor; Cell Survival; Curcumin; DNA; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; Inhibitor of Apoptosis Proteins; NF-kappa B; Quercetin; Signal Transduction; STAT3 Transcription Factor; Stomach Neoplasms; Survivin

2015
Head-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In Vitro.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Berberine; Biological Products; Blood Platelets; Caco-2 Cells; Catechin; Cell Line; Curcumin; Humans; Interleukin-6; Interleukin-8; Macrophages; Mice; Neutrophils; Platelet Activation; Pravastatin; Prednisolone; Primary Cell Culture; Reactive Oxygen Species; Stilbenes; Tumor Necrosis Factor-alpha

2016
Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.
    Scientific reports, 2016, 06-06, Volume: 6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Beclin-1; Berberine; Breast Neoplasms; Cell Growth Processes; Chemoprevention; Curcumin; Drug Synergism; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; MCF-7 Cells; Proto-Oncogene Proteins c-bcl-2

2016
Antidiabetic potential of polyherbal formulation DB14201: Preclinical development, safety and efficacy studies.
    Journal of ethnopharmacology, 2017, Feb-02, Volume: 197

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Berberine; Blood Glucose; Chromatography, Liquid; Curcumin; Diabetes Mellitus, Experimental; Glucose; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Kaempferols; Male; Metals, Heavy; Mice; Mice, Inbred C57BL; Plant Extracts; Rats; Rats, Wistar; Tandem Mass Spectrometry; Tumor Necrosis Factor-alpha; Xanthones

2017
Role of nutraceutical SIRT1 modulators in AMPK and mTOR pathway: Evidence of a synergistic effect.
    Nutrition (Burbank, Los Angeles County, Calif.), 2017, Volume: 34

    Topics: AMP-Activated Protein Kinases; Anthocyanins; Berberine; Catechin; Cell Line, Tumor; Cell Survival; Coumaric Acids; Curcumin; Dietary Supplements; Gene Expression Regulation; Humans; Niclosamide; Phenylethyl Alcohol; Phosphorylation; Quercetin; Resveratrol; Sirtuin 1; Stilbenes; TOR Serine-Threonine Kinases

2017
Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cells-Power of nutraceuticals.
    Advances in biological regulation, 2018, Volume: 67

    Topics: Animals; Antineoplastic Agents; Berberine; Cardiovascular Diseases; Curcumin; Dietary Supplements; Humans; Neoplasms; Resveratrol; Signal Transduction

2018
Natural products berberine and curcumin exhibited better ameliorative effects on rats with non-alcohol fatty liver disease than lovastatin.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Berberine; Biological Products; Blood Glucose; Body Weight; Curcumin; Gene Expression Regulation; Inflammation; Insulin; Intra-Abdominal Fat; Lipid Metabolism; Lipids; Lipopolysaccharides; Liver; Lovastatin; Male; Non-alcoholic Fatty Liver Disease; Organ Size; Oxidative Stress; Rats, Sprague-Dawley

2018
An in vitro comparative study of the antioxidant activity and SIRT1 modulation of natural compounds.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 101

    Topics: AMP-Activated Protein Kinase Kinases; Antioxidants; Berberine; Biological Factors; Cell Survival; Curcumin; HeLa Cells; Humans; Oxidative Stress; Protein Kinases; Quercetin; Sirtuin 1

2018
Novel mitochondrial targeting charge-reversal polysaccharide hybrid shell/core nanoparticles for prolonged systemic circulation and antitumor drug delivery.
    Drug delivery, 2019, Volume: 26, Issue:1

    Topics: Adenine; Animals; Antineoplastic Agents; Berberine; Cell Line; Chitosan; Curcumin; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Endocytosis; Humans; Hyaluronan Receptors; Hyaluronic Acid; Mice; Mice, Nude; Micelles; Mitochondria; Nanoparticles; Polymers; Polysaccharides

2019
Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Berberine; Biological Availability; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; Drug Carriers; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Glioblastoma; Humans; Lipids; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases

2019
Synergic Effects of Berberine and Curcumin on Improving Cognitive Function in an Alzheimer's Disease Mouse Model.
    Neurochemical research, 2020, Volume: 45, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid Endopeptidases; Berberine; Brain; Cognition; Curcumin; Drug Synergism; Female; Male; Mice; Mice, Transgenic; Oxidative Stress; Peptide Fragments

2020
Combinatorial liposomes of berberine and curcumin inhibit biofilm formation and intracellular methicillin resistant
    Journal of materials chemistry. B, 2021, 01-28, Volume: 9, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Berberine; Biofilms; Cells, Cultured; Curcumin; Humans; Inflammation; Liposomes; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Particle Size; Staphylococcal Infections; Surface Properties; THP-1 Cells

2021
One-step synthesis of red emission multifunctional carbon dots for label-free detection of berberine and curcumin and cell imaging.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2021, Apr-15, Volume: 251

    Topics: Berberine; Carbon; Curcumin; Fluorescent Dyes; Quantum Dots; Spectrometry, Fluorescence

2021
Is nutraceutical supplementation appropriate for COVID-19 management?
    Allergy and asthma proceedings, 2021, 05-01, Volume: 42, Issue:3

    Topics: Berberine; Catechin; COVID-19; Curcumin; Dietary Supplements; Humans; Lactobacillus; NF-E2-Related Factor 2; Receptor, Angiotensin, Type 1; SARS-CoV-2

2021
Improving the ameliorative effects of berberine and curcumin combination via dextran-coated bilosomes on non-alcohol fatty liver disease in mice.
    Journal of nanobiotechnology, 2021, Aug-04, Volume: 19, Issue:1

    Topics: Administration, Oral; Animals; Berberine; Biological Availability; Caco-2 Cells; Curcumin; Dextrans; Drug Carriers; Drug Combinations; Humans; Liposomes; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Tissue Distribution

2021
Evaluation of the Effects of Nanomicellar Curcumin, Berberine, and Their Combination with 5-Fluorouracil on Breast Cancer Cells.
    Advances in experimental medicine and biology, 2021, Volume: 1328

    Topics: Apoptosis; Berberine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Curcumin; Drug Synergism; Female; Fluorouracil; Humans

2021
Fabrication, characterization and in vitro cell exposure study of zein-chitosan nanoparticles for co-delivery of curcumin and berberine.
    International journal of biological macromolecules, 2022, Apr-15, Volume: 204

    Topics: Berberine; Chitosan; Curcumin; Nanoparticles; Particle Size; Zein

2022
Carrier-Free Small Molecular Self-Assembly Based on Berberine and Curcumin Incorporated in Submicron Particles for Improving Antimicrobial Activity.
    ACS applied materials & interfaces, 2022, Mar-02, Volume: 14, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Berberine; Curcumin; Drug Compounding

2022
Standardization and Ameliorative effect of Kalyanaka ghrita in β-amyloid induced memory impairment in wistar rats.
    Journal of ethnopharmacology, 2023, Jan-10, Volume: 300

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Berberine; Brain-Derived Neurotrophic Factor; Curcumin; Cytokines; Disease Models, Animal; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Nootropic Agents; Rats; Rats, Wistar; Tannins

2023
A Composition of Phytonutrients for Glycemic and Weight Management.
    Nutrients, 2022, Sep-14, Volume: 14, Issue:18

    Topics: Acrolein; Animals; Berberine; Blood Glucose; Curcumin; Diabetes Mellitus; Disease Models, Animal; Fatty Acids; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Lipids; Mice; Obesity; Phytochemicals; Weight Gain

2022
Functional Complementation of Anti-Adipogenic Phytonutrients for Obesity Prevention and Management.
    Nutrients, 2022, Oct-16, Volume: 14, Issue:20

    Topics: Adipocytes; Adipogenesis; Animals; Berberine; beta Catenin; Cholesterol; Curcumin; Cytokines; Fatty Acids; Glucose; Hesperidin; Humans; Lipoproteins, LDL; Luteolin; Mice; Obesity; Phytochemicals; PPAR gamma; Quercetin; Resveratrol; Sterol Regulatory Element Binding Protein 1; Triglycerides

2022
Virtual screening and antimicrobial evaluation for identification of natural compounds as the prospective inhibitors of antibacterial drug resistance targets in Staphylococcus aureus.
    Fitoterapia, 2023, Volume: 168

    Topics: Anti-Bacterial Agents; Berberine; Curcumin; Drug Resistance, Bacterial; Eugenol; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Quercetin; Staphylococcus aureus; Thymol

2023
Effect of berberine on bone mineral density in SAMP6 as a senile osteoporosis model.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:1

    Topics: Aging; Animals; Berberine; Bone Density; Disease Models, Animal; Female; Hydrastis; Male; Mice; Mice, Mutant Strains; Osteoporosis; Ranunculaceae

2003
[Paper chromatographic separation of d- and 1-canadine].
    Pharmaceutisch weekblad, 1958, Nov-29, Volume: 93, Issue:24

    Topics: Berberine; Biological Products; Chromatography, Paper; Hydrastis; Rare Diseases

1958
The influence of deoxyribonucleic acid on ultraviolet and visible light absorption of berberine.
    Archives of biochemistry and biophysics, 1959, Volume: 81, Issue:1

    Topics: Berberine; Biological Products; DNA; Hydrastis; Light

1959
The absorption, distribution and excretion of berberine.
    Archives internationales de pharmacodynamie et de therapie, 1960, Mar-01, Volume: 124

    Topics: Berberine; Biological Products; Biological Transport; Hydrastis

1960
Conversion of hydrastine into berberine, and an instance of the asymmetrical quaternization of a tertiary base.
    Nature, 1950, Aug-12, Volume: 166, Issue:4215

    Topics: Benzylisoquinolines; Berberine; Biological Products; Humans; Hydrastis

1950
Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts.
    Electrophoresis, 2005, Volume: 26, Issue:12

    Topics: Alkaloids; Benzylisoquinolines; Berberine; Dietary Supplements; Electrophoresis, Capillary; Hydrastis; Plant Extracts; Quality Control; Reproducibility of Results; Sensitivity and Specificity

2005
[Extraction and HPLC analysis of alkaloids in goldenseal].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2004, Volume: 20, Issue:2

    Topics: Benzylisoquinolines; Berberine; Chromatography, High Pressure Liquid; Hydrastis; Plant Roots

2004
Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.). 2. Palmatine, hydrastine, canadine, and hydrastinine.
    Chemical research in toxicology, 2006, Volume: 19, Issue:6

    Topics: Alkaloids; Benzylisoquinolines; Berberine; Berberine Alkaloids; Cell Line; Cell Survival; Humans; Hydrastis; Molecular Structure; Oxygen; Photochemistry; Photosensitizing Agents; Spectrum Analysis; Tetrahydroisoquinolines

2006
The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms.
    Journal of lipid research, 2006, Volume: 47, Issue:10

    Topics: Animals; Berberine; Cell Line; Cholesterol, LDL; Cricetinae; Herbal Medicine; Humans; Hydrastis; Liver; Male; Molecular Structure; Phytotherapy; Plant Extracts; Plant Roots; Plants, Medicinal; RNA, Small Interfering

2006
Microscopic identity tests for hydrastis and its principal alkaloids, hydrastine and berberine.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1948, Volume: 37, Issue:1

    Topics: Alkaloids; Benzylisoquinolines; Berberine; Biological Products; Hydrastis

1948
Seasonal variation of biomass and bioactive alkaloid content of goldenseal, Hydrastis canadensis.
    Fitoterapia, 2010, Volume: 81, Issue:7

    Topics: Benzylisoquinolines; Berberine; Hydrastis; Plant Structures; Seasons

2010
Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition.
    Planta medica, 2011, Volume: 77, Issue:8

    Topics: Alkaloids; Anti-Bacterial Agents; Bacterial Proteins; Benzylisoquinolines; Berberine; Drug Synergism; Ethidium; Hydrastis; Multidrug Resistance-Associated Proteins; Plant Components, Aerial; Plant Extracts; Plant Roots; Staphylococcus aureus

2011
Investigating the potential for toxicity from long-term use of the herbal products, goldenseal and milk thistle.
    Toxicologic pathology, 2011, Volume: 39, Issue:2

    Topics: Animals; Berberine; Body Weight; Carcinogens; Female; Flavonolignans; Hydrastis; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Plant Preparations; Plant Roots; Rats; Rats, Inbred F344; Silybin; Silybum marianum; Silymarin; Topoisomerase Inhibitors; Toxicity Tests, Chronic

2011
Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis).
    International immunopharmacology, 2011, Volume: 11, Issue:11

    Topics: Animals; Antiviral Agents; Berberine; Cell Culture Techniques; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Hydrastis; Immunoblotting; Immunologic Factors; Influenza A Virus, H1N1 Subtype; Macrophages; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Plant Extracts; Viral Proteins

2011
Analysis of goldenseal, Hydrastis canadensis L., and related alkaloids in urine using HPLC with UV detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Jan-01, Volume: 880, Issue:1

    Topics: Benzylisoquinolines; Berberine; Chromatography, High Pressure Liquid; Humans; Hydrastis; Limit of Detection; Linear Models; Plant Extracts; Plant Roots; Reproducibility of Results; Spectrophotometry, Ultraviolet; Substance Abuse Detection

2012
Quorum quenching and antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA).
    Planta medica, 2012, Volume: 78, Issue:14

    Topics: Anti-Bacterial Agents; Berberine; Hydrastis; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Plant Extracts; Plants, Medicinal; Quorum Sensing; Signal Transduction; Virulence

2012
Mechanism study of goldenseal-associated DNA damage.
    Toxicology letters, 2013, Jul-31, Volume: 221, Issue:1

    Topics: Alkaloids; Berberine; Berberine Alkaloids; Comet Assay; DNA; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Gene Expression Regulation, Enzymologic; Gene Silencing; Hep G2 Cells; Hepatocytes; Histones; Humans; Hydrastis; Mutagens; Plant Extracts; RNA, Small Interfering; Structure-Activity Relationship

2013
An ex vivo approach to botanical-drug interactions: a proof of concept study.
    Journal of ethnopharmacology, 2015, Apr-02, Volume: 163

    Topics: Adult; Benzylisoquinolines; Berberine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Female; Herb-Drug Interactions; Humans; Hydrastis; Male; Microsomes, Liver; Midazolam; Plant Extracts; Silybin; Silybum marianum; Silymarin; Tolbutamide; Young Adult

2015
Versatile methods for synthesizing organic acid salts of quaternary berberine-type alkaloids as anti-ulcerative colitis agents.
    Journal of Asian natural products research, 2016, Volume: 18, Issue:6

    Topics: Berberine; Colitis, Ulcerative; Hydrastis; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Regulatory Factor X Transcription Factors; Salts

2016
Variability in Potency Among Commercial Preparations of Berberine.
    Journal of dietary supplements, 2018, May-04, Volume: 15, Issue:3

    Topics: Berberine; Berberis; Capsules; Chromatography, High Pressure Liquid; Costs and Cost Analysis; Dietary Supplements; Food Inspection; Food Labeling; Food Quality; Hydrastis; Hypoglycemic Agents; Hypolipidemic Agents; Internet; Molecular Structure; Pharmacopoeias as Topic; Plant Extracts; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; United States

2018
Biochemometrics to Identify Synergists and Additives from Botanical Medicines: A Case Study with Hydrastis canadensis (Goldenseal).
    Journal of natural products, 2018, 03-23, Volume: 81, Issue:3

    Topics: Alkaloids; Anti-Bacterial Agents; Berberine; Biological Products; Flavonoids; Hydrastis; Mass Spectrometry; Metabolomics; Plant Extracts; Staphylococcus aureus

2018
Quantification of natural products in herbal supplements: A combined NMR approach applied on goldenseal.
    Journal of pharmaceutical and biomedical analysis, 2019, Feb-20, Volume: 165

    Topics: Alkaloids; Benzylisoquinolines; Berberine; Biological Products; Chromatography, High Pressure Liquid; Hydrastis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Extracts; Plant Roots; Reproducibility of Results

2019
Chemical Evaluation of the Effects of Storage Conditions on the Botanical Goldenseal using Marker-based and Metabolomics Approaches.
    The Yale journal of biology and medicine, 2020, Volume: 93, Issue:2

    Topics: Benzylisoquinolines; Berberine; Berberine Alkaloids; Drug Stability; Drug Storage; Humans; Hydrastis; Infections; Mass Spectrometry; Plant Preparations; Plant Roots; Principal Component Analysis

2020
Physiologically based pharmacokinetic model predictions of natural product-drug interactions between goldenseal, berberine, imatinib and bosutinib.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:4

    Topics: Aniline Compounds; Berberine; Biological Products; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Hydrastis; Imatinib Mesylate; Models, Biological; Nitriles; Quinolines

2022
An Integrative Approach to Elucidate Mechanisms Underlying the Pharmacokinetic Goldenseal-Midazolam Interaction: Application of In Vitro Assays and Physiologically Based Pharmacokinetic Models to Understand Clinical Observations.
    The Journal of pharmacology and experimental therapeutics, 2023, Volume: 387, Issue:3

    Topics: Adult; Alkaloids; Berberine; Biological Products; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Hydrastis; Midazolam; Models, Biological

2023