bepridil and propranolol

bepridil has been researched along with propranolol in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (35.00)	18.7374
1990's	3 (15.00)	18.2507
2000's	3 (15.00)	29.6817
2010's	7 (35.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baker, CA; Hageman, WE; Maryanoff, BE; McComsey, DF; Nortey, SO; Zelesko, MJ	1
Topliss, JG; Yoshida, F	1
Faller, B; Trunzer, M; Zimmerlin, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Brouillette, WJ; Brown, GB; Zha, C	1
Bavari, S; Besch, R; Duplantier, AJ; Jay, WB; Kota, KP; Kuehl, K; Lazić, M; Mudhasani, R; Panchal, RG; Pavić, A; Retterer, C; Sean, VA; Selaković, Ž; Šolaja, BA; Soloveva, V; Tran, JP; Vasiljević, B; Verbić, T	1
Boucher, CA; Christensen, DM; Higgins, J; Zusman, RM	1
Frishman, WH	1
Boissel, JP; Destors, JM; Philippon, AM; Schbath, J	1
Brannan, MD; Flaim, SF; Gill, A; Gleason, MM	1
Farrell, B; Parker, JO	1
Charlap, S; Crawford, MH; DiBianco, R; Farnham, DJ; Frishman, WH; Kostis, JB; Michelson, EL; Michie, DD; Sawin, HS; Zellner, SR	1
Beattie, JM; Hutton, I; Lawrie, TD; Rae, AP	1
Beaughard, M; Labrid, C; Lamar, JC; Piris, P	1
Chen, DD; Dai, DZ; Lu, J; Zhang, XK	1

Trials

5 trial(s) available for bepridil and propranolol

Article	Year
Comparative efficacy and concomitant use of bepridil and beta blockers in the management of angina pectoris. The American journal of cardiology, 1992, Apr-09, Volume: 69, Issue:11 Topics: Aged; Angina Pectoris; Bepridil; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Propranolol	1992
Controlled clinical trial of bepridil, propranolol and placebo in the treatment of exercise induced angina pectoris. B.I.S. Research Group. Fundamental & clinical pharmacology, 1989, Volume: 3, Issue:6 Topics: Adult; Aged; Angina Pectoris; Bepridil; Double-Blind Method; Electrocardiography; Exercise; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroglycerin; Patient Compliance; Propranolol; Randomized Controlled Trials as Topic	1989
Comparative antianginal effects of bepridil and propranolol in angina pectoris. The American journal of cardiology, 1986, Sep-01, Volume: 58, Issue:6 Topics: Aged; Angina Pectoris; Bepridil; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Propranolol; Pyrrolidines	1986
Combination propranolol and bepridil therapy in stable angina pectoris. The American journal of cardiology, 1985, Mar-15, Volume: 55, Issue:7 Topics: Angina Pectoris; Bepridil; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Propranolol; Pyrrolidines	1985
Comparative clinical efficacy of bepridil, propranolol and placebo in patients with chronic stable angina. British journal of clinical pharmacology, 1985, Volume: 19, Issue:3 Topics: Adult; Angina Pectoris; Bepridil; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Hemodynamics; Humans; Male; Middle Aged; Propranolol; Pyrrolidines; Random Allocation	1985

Other Studies

15 other study(ies) available for bepridil and propranolol

Article	Year
Cardiac-slowing amidines containing the 3-thioindone group. Potential antianginal agents. Journal of medicinal chemistry, 1983, Volume: 26, Issue:2 Topics: Amidines; Aminophylline; Angina Pectoris; Animals; Benzilates; Biological Assay; Dogs; Glucagon; Heart Rate; Indicators and Reagents; Indoles; Myocardial Contraction; Structure-Activity Relationship; Tachycardia	1983
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation. Journal of medicinal chemistry, 2009, Jan-22, Volume: 52, Issue:2 Topics: Chromatography, Liquid; Drug Design; Humans; Likelihood Functions; Microsomes, Liver; Pharmacokinetics; Tandem Mass Spectrometry	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels	2014
Second generation of diazachrysenes: Protection of Ebola virus infected mice and mechanism of action. European journal of medicinal chemistry, 2019, Jan-15, Volume: 162 Topics: Animals; Antiviral Agents; Chrysenes; Ebolavirus; Hemorrhagic Fever, Ebola; Lysosomes; Mice; Surface-Active Agents; Virus Internalization; Zebrafish	2019
Effects of antianginal therapy on left ventricular systolic and diastolic performance: comparison of the response to bepridil, propranolol, and diltiazem. The American journal of cardiology, 1992, Apr-09, Volume: 69, Issue:11 Topics: Angina Pectoris; Bepridil; Diastole; Diltiazem; Exercise Test; Humans; Propranolol; Systole; Vascular Resistance; Ventricular Function, Left	1992
Effects of bepridil hydrochloride on calcium-induced responses in guinea pig Langendorff heart. Pharmacology, 1986, Volume: 33, Issue:2 Topics: Animals; Bepridil; Calcium; Calcium Channel Blockers; Coronary Circulation; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Lanthanum; Lidocaine; Male; Myocardial Contraction; Propranolol; Pyrrolidines; Time Factors	1986
Bepridil-induced modifications of cardiac performance in the anesthetized dog: comparison with nitroglycerin and propranolol. Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 255, Issue:2 Topics: Anesthesia; Angina Pectoris; Animals; Bepridil; Blood Pressure; Cardiac Output; Dogs; Female; Heart Rate; Male; Myocardial Contraction; Nitroglycerin; Propranolol; Pyrrolidines; Stroke Volume	1982
Propranolol and bepridil attenuating levothyroxine-induced rat cardiac hypertrophy and mitochondrial Ca2+ Mg(2+)-ATPase activity elevation. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:6 Topics: Adrenergic beta-Antagonists; Animals; Bepridil; Ca(2+) Mg(2+)-ATPase; Calcium Channel Blockers; Cardiomegaly; Female; Mitochondria, Heart; Propranolol; Rats; Rats, Sprague-Dawley; Thyroxine	1996