bepridil and nitrendipine

bepridil has been researched along with nitrendipine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19909 (37.50)18.7374
1990's3 (12.50)18.2507
2000's7 (29.17)29.6817
2010's5 (20.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Keserü, GM1
Nagashima, R; Nishikawa, T; Tobita, M1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Jia, L; Sun, H1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Sen, S; Sinha, N1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Brouillette, WJ; Brown, GB; Zha, C1
Braun, S; Frey, N; Herzig, S; Hilbert, C1
Culliford, SJ; Ellory, JC; Horwitz, E; Nash, GB; Stone, PC; Stuart, J1
Balwierczak, JL; Grupp, G; Grupp, IL; Schwartz, A1
Brown, NL; Sirugue, O; Worcel, M1
Lamers, JM; Mas-Oliva, J; Verdouw, PD1
Baky, S; Nademanee, K; Singh, BN1
Hasegawa, GR1
Fosset, M; Galizzi, JP; Lazdunski, M1
Pang, DC; Sperelakis, N1
Jespersen, LT; Mikkelsen, E; Pedersen, OL1
Stoeckel, H; Takeda, K1
Brand-Schieber, E; Werner, P1

Reviews

2 review(s) available for bepridil and nitrendipine

ArticleYear
Second-generation calcium antagonists: search for greater selectivity and versatility.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Bepridil; Calcium Channel Blockers; Cinnarizine; Electrophysiology; Flunarizine; Heart; Humans; Lidoflazine; Muscle, Smooth, Vascular; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyrrolidines; Structure-Activity Relationship

1985
Nicardipine, nitrendipine, and bepridil: new calcium antagonists for cardiovascular disorders.
    Clinical pharmacy, 1988, Volume: 7, Issue:2

    Topics: Bepridil; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Nicardipine; Nitrendipine; Pyrrolidines

1988

Other Studies

22 other study(ies) available for bepridil and nitrendipine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
    Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection

2011
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels

2014
Potentiation of cardiodepressive action among calcium antagonists from different classes: evidence for a mechanism at the single calcium channel level.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:5

    Topics: Animals; Bepridil; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Nitrendipine

1992
Mode of action and comparative efficacy of pharmacological agents that inhibit calcium-dependent dehydration of sickle cells.
    British journal of pharmacology, 1992, Volume: 106, Issue:4

    Topics: Anemia, Sickle Cell; Azepines; Bepridil; Calcium; Calcium Channel Blockers; Erythrocytes, Abnormal; Fendiline; Humans; In Vitro Techniques; Nitrendipine; Oxygen; Potassium Channels

1992
Effects of bepridil and diltiazem on [3H]nitrendipine binding to canine cardiac sarcolemma. Potentiation of pharmacological effects of nitrendipine by bepridil.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:1

    Topics: Animals; Benzazepines; Bepridil; Binding Sites; Binding, Competitive; Diltiazem; Dogs; Drug Synergism; In Vitro Techniques; Kinetics; Myocardial Contraction; Nifedipine; Nitrendipine; Pyrrolidines; Rats; Sarcolemma; Temperature

1986
The effects of some slow channel blocking drugs on high affinity serotonin uptake by rat brain synaptosomes.
    European journal of pharmacology, 1986, Apr-09, Volume: 123, Issue:1

    Topics: Animals; Bepridil; Brain; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Pyrrolidines; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes; Temperature; Time Factors; Verapamil

1986
The effects of felodipine and bepridil on calcium-stimulated calmodulin binding and calcium pumping ATPase of cardiac sarcolemma before and after removal of endogenous calmodulin.
    Molecular and cellular biochemistry, 1987, Volume: 78, Issue:2

    Topics: Animals; Bepridil; Calcium; Calcium-Transporting ATPases; Calmodulin; Felodipine; Imidazoles; In Vitro Techniques; Myocardium; Nitrendipine; Pyrrolidines; Sarcolemma

1987
Properties of receptors for the Ca2+-channel blocker verapamil in transverse-tubule membranes of skeletal muscle. Stereospecificity, effect of Ca2+ and other inorganic cations, evidence for two categories of sites and effect of nucleoside triphosphates.
    European journal of biochemistry, 1984, Oct-15, Volume: 144, Issue:2

    Topics: Animals; Bepridil; Binding, Competitive; Calcium; Calcium Channels; Cations, Divalent; Cations, Monovalent; Diltiazem; Electrochemistry; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Muscles; Nifedipine; Nitrendipine; Nucleotides; Pyrrolidines; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil

1984
Uptake of calcium antagonistic drugs into muscles as related to their lipid solubilities.
    Biochemical pharmacology, 1984, Mar-01, Volume: 33, Issue:5

    Topics: Animals; Bepridil; Calcium Channel Blockers; Lipid Metabolism; Muscles; Nifedipine; Nitrendipine; Pyrrolidines; Rana pipiens; Rats; Sarcoplasmic Reticulum; Solubility; Verapamil

1984
Effects of two new Ca-entry blockers bepridil and nitrendipine on isolated vessels.
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:4

    Topics: Adult; Aged; Animals; Aorta, Thoracic; Bepridil; Calcium Channel Blockers; Female; Femoral Vein; Humans; In Vitro Techniques; Leg; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Norepinephrine; Portal Vein; Potassium; Pyrrolidines; Rats; Veins

1984
Calcium-sensitivity of the plasmalemmal delayed rectifier potassium current suggests that calcium influx in pulvinar protoplasts from Mimosa pudica L. can be revealed by hyperpolarization.
    The Journal of membrane biology, 1995, Volume: 146, Issue:2

    Topics: Bepridil; Calcium; Calcium Channel Blockers; Cells, Cultured; Electric Conductivity; Ionomycin; Ionophores; Nitrendipine; Plant Physiological Phenomena; Potassium Channels; Protoplasts; Pulvinus; Verapamil

1995
Calcium channel blockers ameliorate disease in a mouse model of multiple sclerosis.
    Experimental neurology, 2004, Volume: 189, Issue:1

    Topics: Animals; Axons; Bepridil; Calcium Channel Blockers; Calcium Channels, L-Type; Demyelinating Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Immunohistochemistry; Mice; Multiple Sclerosis; Myelin Basic Protein; Neutrophil Infiltration; Nitrendipine; Spinal Cord; Time Factors; Wallerian Degeneration

2004