bepridil and nicardipine

bepridil has been researched along with nicardipine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19907 (36.84)18.7374
1990's3 (15.79)18.2507
2000's5 (26.32)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Aszalos, A; Ibrahim, S; Knapton, A; Licht, T; Peggins, J1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bradley, KA; Damoiseaux, R; Gillespie, EJ; Huang, J; Manchester, M; Rogers, J; Sanchez, AM; Saxe, JP; Thomas, D1
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Crevat, A; Gallice, P; Kovacic, H1
Adam, LP; Henderson, EG2
Albengres, E; Crevat, A; Ducet, G; Fournier, N; Tari, C; Tillement, JP; Urien, S1
Follenius-Wund, A; Gerard, D; Luginer, C; Schaeffer, P; Stoclet, JC1
Baky, S; Nademanee, K; Singh, BN1
Hasegawa, GR1
Dang Tran, L; Gaillard, G; Montastruc, JL; Montastruc, P; Valet, P1
Advenier, C; Cerrina, J; Duroux, P; Floch, A; Renier, A1
Chauvet-Monges, AM; Crevat, A; Salducci, MD; Tabouy, L1

Reviews

2 review(s) available for bepridil and nicardipine

ArticleYear
Second-generation calcium antagonists: search for greater selectivity and versatility.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Bepridil; Calcium Channel Blockers; Cinnarizine; Electrophysiology; Flunarizine; Heart; Humans; Lidoflazine; Muscle, Smooth, Vascular; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Pyrrolidines; Structure-Activity Relationship

1985
Nicardipine, nitrendipine, and bepridil: new calcium antagonists for cardiovascular disorders.
    Clinical pharmacy, 1988, Volume: 7, Issue:2

    Topics: Bepridil; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Nicardipine; Nitrendipine; Pyrrolidines

1988

Other Studies

17 other study(ies) available for bepridil and nicardipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Influence of antipsychotic, antiemetic, and Ca(2+) channel blocker drugs on the cellular accumulation of the anticancer drug daunorubicin: P-glycoprotein modulation.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:3

    Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Antiemetics; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Calcium Channel Blockers; Daunorubicin; Flow Cytometry; Humans; Mice; Transfection

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Amiodarone and bepridil inhibit anthrax toxin entry into host cells.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Amiodarone; Animals; Anthrax; Antigens, Bacterial; Bacterial Toxins; Bepridil; Cell Line; Cell Survival; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Macrophages, Peritoneal; Male; Mice; Molecular Structure; Rats; Rats, Inbred F344; Time Factors

2007
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers

2007
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Inhibition of sodium pump by bepridil. An in vitro and microcalorimetric study.
    Biochemical pharmacology, 1992, Oct-20, Volume: 44, Issue:8

    Topics: Adenosine Triphosphate; Bepridil; Diltiazem; Erythrocytes; Humans; Kinetics; Nicardipine; Nifedipine; Ouabain; Potassium; Sodium-Potassium-Exchanging ATPase; Verapamil

1992
Calcium channel effectors are potent non-competitive blockers of acetylcholine receptors.
    Pflugers Archiv : European journal of physiology, 1990, Volume: 416, Issue:5

    Topics: Animals; Bepridil; Calcium Channel Agonists; Calcium Channels; Cell Membrane; Electric Conductivity; Electric Organ; Electrophysiology; Ion Channel Gating; Mice; Motor Endplate; Muscle Contraction; Nicardipine; Nicotinic Antagonists; Phencyclidine; Rana pipiens; Torpedo

1990
Comparative study of bepridil and nicardipine action on respiration and calcium transport in mitochondria.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Bepridil; Biological Transport; Calcium; Calcium Channel Blockers; Humans; Mitochondria, Liver; Nicardipine; Oxygen Consumption; Pyrrolidines; Rats

1987
Augmentation of succinylcholine-induced neuromuscular blockade by calcium channel antagonists.
    Neuroscience letters, 1986, Sep-25, Volume: 70, Issue:1

    Topics: Animals; Bepridil; Calcium Channel Blockers; Drug Synergism; In Vitro Techniques; Neuromuscular Junction; Nicardipine; Nifedipine; Pyrrolidines; Rana pipiens; Receptors, Nicotinic; Succinylcholine; Synaptic Transmission; Verapamil

1986
Comparative effects of calmodulin inhibitors on calmodulin's hydrophobic sites and on the activation of cyclic nucleotide phosphodiesterase by calmodulin.
    Biochemical pharmacology, 1987, Jun-15, Volume: 36, Issue:12

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Bepridil; Calmodulin; Cattle; Choline; Drug Interactions; Enzyme Activation; Naphthalenesulfonates; Nicardipine; Nicergoline; Pyrrolidines; Quercetin; Sulfonamides

1987
Effects of calcium entry blockers on blood pressure and heart rate in neurogenic hypertensive dogs.
    Fundamental & clinical pharmacology, 1987, Volume: 1, Issue:2

    Topics: Animals; Bepridil; Blood Pressure; Calcium Channel Blockers; Denervation; Diltiazem; Dogs; Female; Heart Rate; Hypertension; Male; Nicardipine; Nifedipine; Pyrrolidines; Sinoatrial Node; Verapamil

1987
Effects of five different organic calcium antagonists on guinea-pig isolated trachea.
    British journal of pharmacology, 1984, Volume: 82, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Bepridil; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicardipine; Nifedipine; Pyrrolidines; Trachea; Verapamil

1984
Protective effect of some calcium antagonists against mitochondrial calcium injury.
    International journal of tissue reactions, 1994, Volume: 16, Issue:5-6

    Topics: Adenosine Triphosphate; Amlodipine; Animals; Antihypertensive Agents; Bepridil; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Mitochondria, Liver; Myocardial Ischemia; Nicardipine; Rats; Rats, Wistar; Verapamil

1994