bepridil has been researched along with amiodarone in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (21.95) | 18.7374 |
| 1990's | 4 (9.76) | 18.2507 |
| 2000's | 15 (36.59) | 29.6817 |
| 2010's | 12 (29.27) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Keserü, GM | 1 |
| Cianchetta, G; Cruciani, G; Fravolini, A; Giesing, D; Singleton, RW; Vaz, RJ; Wildgoose, M; Zhang, M | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bradley, KA; Damoiseaux, R; Gillespie, EJ; Huang, J; Manchester, M; Rogers, J; Sanchez, AM; Saxe, JP; Thomas, D | 1 |
| Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Jia, L; Sun, H | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Sen, S; Sinha, N | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Honjo, H; Iwata, H; Kamiya, K; Kodama, I; Osaka, T; Toyama, J | 1 |
| Connell, MJ; Cumiskey, WR; Dillon, KM; Ezrin, AM; Silver, PJ; Volberg, WA | 1 |
| Dujardin, JJ; Haiat, R; Joly, P; Kacet, S; Nicolai, P | 1 |
| Somberg, J | 1 |
| Horowitz, LN; Morganroth, J | 1 |
| Krikler, DM; McKenna, WJ; Perelman, MS; Rowland, E | 1 |
| Borchard, U; Dietrich, H; Hafner, D; Hirth, C | 1 |
| Somberg, JC | 1 |
| Cheucle-Beaughard, M; Duchene-Marullaz, P; Michelin, MT | 1 |
| Basiez, M; Beaughard, M; Duchene-Marullaz, P; Labrid, C; Leinot, M | 1 |
| Fromm, BS; Lehmann, MH; Makkar, RR; Meissner, MD; Steinman, RT | 1 |
| Pollak, PT | 1 |
| Kobayashi, S; Masuda, Y; Nakaya, H; Ogura, T; Reien, Y; Saito, T | 1 |
| Kasanuki, H | 1 |
| Fujiki, A | 1 |
| Sugi, K | 1 |
| Hadano, Y; Iwami, T; Kimura, M; Matsuzaki, M; Miyazaki, Y; Ogawa, H; Shimizu, A; Takaki, A; Wakeyama, T | 1 |
| Nakamura, Y; Sugiyama, A; Takahara, A | 1 |
| Ha, HR; Haass, C; Hamid, R; Herms, J; Hopson, J; Kamp, F; Lichtenthaler, SF; Mayer, TU; Mitterreiter, S; Nelson, DJ; Page, RM; Rossner, S; Stahl, T; Steiner, H; Winkler, E; Zeitschel, U | 1 |
| Bittner, T; Brouwers, N; Capell, A; Carlson, AM; Cruts, M; Dormann, D; Fellerer, K; Gijselinck, I; Haass, C; Herms, J; Jansen, R; Kunze, B; Lammich, S; Liebscher, S; Sasse, F; Sleegers, K; Steinmetz, H; Van Broeckhoven, C; Willem, M | 1 |
| Daida, H; Nakazato, Y; Yamase, M | 1 |
| Iitsuka, K; Kato, M; Kondo, T; Miake, J; Ogura, K; Yamamoto, K | 1 |
| Chiba, T; Kondo, N; Takahara, A | 1 |
| Chiba, K; Goto, A; Hagiwara-Nagasawa, M; Izumi-Nakaseko, H; Kanda, Y; Naito, AT; Sekino, Y; Sugiyama, A | 1 |
| Kimura, A; Murakami, S | 1 |
7 review(s) available for bepridil and amiodarone
| Article | Year |
|---|---|
Effects of amiodarone and bepridil on ventricular depolarization and repolarization.
Topics: Amiodarone; Animals; Bepridil; Electrocardiography; Heart Conduction System; Lidocaine; Membrane Potentials; Sodium Channels | 1992 |
Antiarrhythmic drug therapy. Recent advances and current status.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil | 1985 |
Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Bepridil; Cardiovascular Agents; Disopyramide; Female; Humans; Male; Middle Aged; Prenylamine; Procainamide; Quinidine; Risk Factors; Sex; Sotalol; Syncope; Tachycardia, Ventricular; Torsades de Pointes | 1993 |
A systematic review and critical comparison of internal standards for the routine liquid chromatographic assay of amiodarone and desethylamiodarone.
Topics: Amiodarone; Anti-Arrhythmia Agents; Bepridil; Chromatography, High Pressure Liquid; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Monitoring; Estrogen Antagonists; Tamoxifen; Trifluoperazine | 1996 |
[New generation of antiarrhythmic drug].
Topics: Amiodarone; Anti-Arrhythmia Agents; Bepridil; Coronary Disease; Humans; Randomized Controlled Trials as Topic; Tachycardia, Supraventricular; Treatment Outcome | 1994 |
[Present status in and prospects for anti-arrhythmic drug therapy: How to use type III anti-arrhythmic agents].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bepridil; Drug Therapy, Combination; Humans; Pyrimidinones; Sotalol | 2006 |
[Strategy for cardiac arrhythmias in acute coronary syndrome].
Topics: Amiodarone; Angina, Unstable; Anti-Asthmatic Agents; Aprindine; Atrial Fibrillation; Bepridil; Electric Countershock; Humans; Myocardial Infarction; Potassium Channel Blockers; Pyrimidinones; Recurrence; Syndrome; Tachycardia, Ventricular; Ventricular Fibrillation | 2006 |
1 trial(s) available for bepridil and amiodarone
| Article | Year |
|---|---|
Effectiveness of amiodarone versus bepridil in achieving conversion to sinus rhythm in patients with persistent atrial fibrillation: a randomised trial.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bepridil; Dose-Response Relationship, Drug; Electrocardiography; Female; Follow-Up Studies; Heart Rate; Humans; Male; Middle Aged; Prospective Studies; Time Factors; Treatment Outcome | 2012 |
33 other study(ies) available for bepridil and amiodarone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Fluoresceins; Fluorescent Dyes; Humans; Models, Molecular; Multivariate Analysis; Permeability; Quantitative Structure-Activity Relationship | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Amiodarone and bepridil inhibit anthrax toxin entry into host cells.
Topics: Amiodarone; Animals; Anthrax; Antigens, Bacterial; Bacterial Toxins; Bepridil; Cell Line; Cell Survival; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Macrophages, Peritoneal; Male; Mice; Molecular Structure; Rats; Rats, Inbred F344; Time Factors | 2007 |
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
Inhibition of calmodulin and protein kinase C by amiodarone and other class III antiarrhythmic agents.
Topics: Actomyosin; Amiodarone; Animals; Anti-Arrhythmia Agents; Bepridil; Calcium; Calmodulin; Guinea Pigs; Imidazoles; Kinetics; Male; Phosphodiesterase Inhibitors; Protein Kinase C; Quaternary Ammonium Compounds; Sotalol | 1989 |
[Drug-induced major anomalies of ventricular repolarization masked by a left branch block].
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bepridil; Bundle-Branch Block; Electrocardiography; Electrophysiology; Female; Heart Ventricles; Humans; Male; Middle Aged; Pyrrolidines | 1989 |
Are there unnecessary delays in the development of new cardiac drugs in the United States?
Topics: Amiodarone; Bepridil; Flecainide; Humans; Pyrrolidines; United States; United States Food and Drug Administration | 1986 |
A comparison of bepridil with amiodarone in the treatment of established atrial fibrillation.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Bepridil; Chronic Disease; Electrocardiography; Female; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Pyrrolidines | 1987 |
Antiarrhythmic and electrophysiological actions of flecainide, bepridil and amiodarone on isolated heart preparations during controlled hypoxia.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Bepridil; Electrophysiology; Flecainide; Guinea Pigs; Heart; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Oxygen; Papillary Muscles; Piperidines; Pyrrolidines; Time Factors | 1985 |
New directions in antiarrhythmic drug therapy.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil | 1984 |
Comparative effects of amiodarone, bepridil and perhexiline on coronary venous flow and several cardiovascular parameters.
Topics: Amines; Amiodarone; Animals; Benzofurans; Benzylamines; Bepridil; Coronary Circulation; Denervation; Dogs; Female; Heart; Heart Rate; Hemodynamics; Male; Oxygen Consumption; Perhexiline; Piperidines; Pyrrolidines; Time Factors | 1980 |
Comparative antidysrhythmic profiles of bepridil, amiodarone and disopyramide in the guinea-pig and dog.
Topics: Aconitine; Amiodarone; Animals; Anti-Arrhythmia Agents; Benzofurans; Bepridil; Disopyramide; Dogs; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Injections, Intraventricular; Male; Pyridines; Pyrrolidines; Ventricular Fibrillation | 1981 |
Inhibitory effect of bepridil on hKv1.5 channel current: comparison with amiodarone and E-4031.
Topics: 4-Aminopyridine; Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Function; Bepridil; Dose-Response Relationship, Drug; Gene Expression; Heart Atria; Humans; In Vitro Techniques; Kv1.5 Potassium Channel; Membrane Potentials; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Rats | 2001 |
[Cardioversion of amiodarone-insensitive atrial fibrillation by bepridil in heart failure: two case reports].
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bepridil; Cardiomyopathy, Dilated; Humans; Lung Diseases, Interstitial; Male; Tachycardia, Ventricular | 2006 |
Beat-to-beat variability of repolarization differentiates the extent of torsadogenic potential of multi ion channel-blockers bepridil and amiodarone.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrioventricular Block; Bepridil; Dogs; Electrocardiography; Female; Heart; Heart Rate; Ion Channels; Male; Torsades de Pointes | 2008 |
Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms.
Topics: Alzheimer Disease; Amiodarone; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Bepridil; Brain; Cell Line; Cells, Cultured; Enzyme Inhibitors; Female; Guinea Pigs; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Mice, Transgenic; Neurons; Protease Nexins; Receptors, Cell Surface | 2010 |
Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase.
Topics: Alkalies; Amiodarone; Animals; Animals, Newborn; Autophagy-Related Protein 5; Bepridil; Blotting, Northern; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebral Cortex; Chloroquine; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Frontotemporal Lobar Degeneration; Granulins; HEK293 Cells; HeLa Cells; Humans; Intercellular Signaling Peptides and Proteins; Macrolides; Male; Mice; Microtubule-Associated Proteins; Mutation; Neurons; Progranulins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Vacuolar Proton-Translocating ATPases | 2011 |
Impact of postprocedural antiarrhythmic drug therapy with bepridil on maintaining sinus rhythm after catheter ablation for persistent atrial fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bepridil; Case-Control Studies; Catheter Ablation; Female; Follow-Up Studies; Humans; Male; Middle Aged; Recurrence; Sodium Channel Blockers | 2016 |
Influences of rapid pacing-induced electrical remodeling on pharmacological manipulation of the atrial refractoriness in rabbits.
Topics: Amiodarone; Animals; Anisoles; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Remodeling; Bepridil; Cardiac Pacing, Artificial; Disease Models, Animal; Infusions, Intravenous; Male; Pyrrolidines; Rabbits; Sotalol | 2016 |
Application of human induced pluripotent stem cell-derived cardiomyocytes sheets with microelectrode array system to estimate antiarrhythmic properties of multi-ion channel blockers.
Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Bepridil; Calcium Channel Blockers; Cells, Cultured; Drug Evaluation, Preclinical; Electrophysiological Phenomena; Humans; Induced Pluripotent Stem Cells; Microelectrodes; Myocytes, Cardiac; Piperidines; Potassium Channel Blockers; Pyridines; Sodium Channel Blockers | 2018 |
Different voltage dependence of I
Topics: Action Potentials; Amiodarone; Arrhythmias, Cardiac; Bepridil; Calcium Channels, L-Type; Computer Simulation; Heart Ventricles; Humans; Membrane Potentials; Models, Theoretical; Myocytes, Cardiac; Potassium; Terfenadine | 2021 |