bepridil and amiloride

bepridil has been researched along with amiloride in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.76)18.7374
1990's10 (58.82)18.2507
2000's4 (23.53)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Baba, A; Matsuda, T; Shimizu, I1
Abe, T; Maseki, T; Tomita, T1
Miller, RC; Schoeffter, P1
Garcia, ML; Kaczorowski, GJ; King, VF; Slaughter, RS1
Haist, JV; Karmazyn, M; Ray, M1
Lee, YS; Sayeed, MM; Wurster, RD1
Crevat, A; Gallice, P; Kovacic, H; Sarrazin, M1
Cragoe, EJ; Lipsky, PE; Wacholtz, MC1
Handa, M; Honda, S; Ikeda, Y; Kanakura, Y; Kashiwagi, H; Kosugi, S; Kurata, Y; Matsuzawa, Y; Shiraga, M; Tomiyama, Y1
Chapman, RA; Chatamra, KR1
Honda, S; Kanakura, Y; Kosugi, S; Kurata, Y; Matsuzawa, Y; Shiraga, M; Suzuki, H; Tadokoro, S; Tanoue, K; Tomiyama, Y1
Amoroso, S; Bernardi, G; Calabresi, P; Marfia, GA; Pisani, A1
Amoroso, S; Annunziato, L; Catalano, A; Di Renzo, G; Montagnani, S; Secondo, A; Tortiglione, A1
Kang, YY; Kim, JA; Lee, YS1
Bondioli, KR; Bonk, AJ; Macháty, Z; Prather, RS; Ramsoondar, JJ1

Other Studies

17 other study(ies) available for bepridil and amiloride

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Na+ influx-induced decrease of (Na+ + K+)-ATPase activity in rat brain slices: role of Ca2+.
    European journal of pharmacology, 1991, Nov-12, Volume: 204, Issue:3

    Topics: Amiloride; Animals; Bepridil; Brain; Calcium; Calcium Channel Blockers; Cell Membrane; Chelating Agents; Diazepam; Egtazic Acid; In Vitro Techniques; Kinetics; Male; Monensin; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Quinacrine; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil; Veratrine

1991
Pharmacological properties of contraction caused by sodium removal in muscle strips isolated from canine coronary artery.
    European journal of pharmacology, 1990, Nov-13, Volume: 190, Issue:3

    Topics: Amiloride; Animals; Arteries; Bepridil; Coronary Vessels; Dogs; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Ouabain; Phentolamine; Potassium; Sodium; Verapamil

1990
Role of sodium-calcium exchange and effects of calcium entry blockers on endothelial-mediated responses in rat isolated aorta.
    Molecular pharmacology, 1986, Volume: 30, Issue:1

    Topics: Amiloride; Animals; Aorta; Bepridil; Calcium; Calcium Channel Blockers; Choline; Cyclic GMP; Diltiazem; Endothelium; Female; Lithium; Muscle, Smooth, Vascular; Nicergoline; Nifedipine; Pyrrolidines; Rats; Rats, Inbred Strains; Reserpine; Sodium; Verapamil

1986
Block of cardiac sodium-calcium exchange by mechanism-based inhibitors.
    Progress in clinical and biological research, 1988, Volume: 252

    Topics: Amiloride; Animals; Bepridil; Binding Sites; Biological Transport, Active; Calcium; Calcium Channel Blockers; Carrier Proteins; In Vitro Techniques; Ion Exchange; Kinetics; Membrane Proteins; Myocardium; Pyrrolidines; Sodium; Sodium-Calcium Exchanger

1988
Comparative effects of Na+/H+ exchange inhibitors against cardiac injury produced by ischemia/reperfusion, hypoxia/reoxygenation, and the calcium paradox.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:1

    Topics: Adenosine Triphosphate; Amiloride; Animals; Bepridil; Calcium; Carrier Proteins; Glycogen; Heart; Heart Rate; Hydrogen; Hypoxia; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers

1993
Intracellular Ca2+ mediates the cytotoxicity induced by bepridil and benzamil in human brain tumor cells.
    Cancer letters, 1995, Jan-06, Volume: 88, Issue:1

    Topics: Amiloride; Astrocytoma; Bepridil; Brain Neoplasms; Calcium; Cell Division; Cytoplasm; Humans; Neuroblastoma; Nickel; Tumor Cells, Cultured

1995
Chloride dependent intracellular pH increase induced by bepridil in human red blood cells: a possible involvement in correction of ischemic acidosis.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Bepridil; Calcium; Carbonic Anhydrases; Chlorides; Erythrocytes; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ischemia; Magnetic Resonance Spectroscopy; Membrane Potentials; Methazolamide; Phosphorus; Potassium; Sodium; Sodium-Hydrogen Exchangers

1993
Delineation of the role of a Na+/Ca2+ exchanger in regulating intracellular Ca2+ in T cells.
    Cellular immunology, 1993, Volume: 147, Issue:1

    Topics: Amiloride; Antibodies, Monoclonal; Bepridil; Calcium; Carrier Proteins; CD3 Complex; Cell Line; Cells, Cultured; Humans; Lithium; Lymphocyte Activation; Mitosis; Sodium-Calcium Exchanger; T-Lymphocytes

1993
Affinity modulation of the platelet integrin alpha IIb beta 3 by alpha-chymotrypsin: a possible role for Na+/Ca2+ exchanger.
    Blood, 1996, Oct-01, Volume: 88, Issue:7

    Topics: Amiloride; Antibodies, Monoclonal; Bepridil; Biological Transport, Active; Calcium; Carrier Proteins; Chymotrypsin; Enzyme Inhibitors; Fibrinogen; Humans; Ouabain; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Quaternary Ammonium Compounds; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase

1996
The effects of sodium-calcium exchange inhibitors on protein loss associated with the calcium paradox of the isolated Langendorff perfused guinea-pig heart.
    Experimental physiology, 1996, Volume: 81, Issue:2

    Topics: Amiloride; Amines; Animals; Bepridil; Calcium; Calcium Channel Blockers; Calcium Channels; Carrier Proteins; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Isradipine; Male; Manganese; Myocardium; Myoglobin; Nickel; Perfusion; Sodium-Calcium Exchanger

1996
Involvement of Na+/Ca2+ exchanger in inside-out signaling through the platelet integrin IIbbeta3.
    Blood, 1998, Nov-15, Volume: 92, Issue:10

    Topics: Amiloride; Bepridil; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Chymotrypsin; Cytoplasmic Granules; Fibrinogen; Humans; Ion Transport; Myosin Light Chains; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Processing, Post-Translational; Serotonin; Signal Transduction; Sodium; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate

1998
Pharmacological inhibition of the Na(+)/Ca(2+) exchanger enhances depolarizations induced by oxygen/glucose deprivation but not responses to excitatory amino acids in rat striatal neurons.
    Stroke, 1999, Volume: 30, Issue:8

    Topics: Amiloride; Animals; Bepridil; Calcium Channel Blockers; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acids; Glucose; Hypoxia, Brain; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium-Calcium Exchanger; Tetrodotoxin

1999
Sodium nitroprusside prevents chemical hypoxia-induced cell death through iron ions stimulating the activity of the Na+-Ca2+ exchanger in C6 glioma cells.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Bepridil; Calcium; Calcium Channel Blockers; Cell Hypoxia; Cell Survival; Chelating Agents; Chlorides; Deferoxamine; Enzyme Activation; Extracellular Space; Ferric Compounds; Ferricyanides; Fluoresceins; Glioma; L-Lactate Dehydrogenase; Molsidomine; Nitric Oxide; Nitroprusside; Sodium; Sodium Channels; Sodium-Calcium Exchanger; Staining and Labeling; Tetrodotoxin; Tumor Cells, Cultured; Vasodilator Agents

2000
Activation of Na(+), K(+), Cl(-)-cotransport mediates intracellular Ca(2+) increase and apoptosis induced by Pinacidil in HepG2 human hepatoblastoma cells.
    Biochemical and biophysical research communications, 2001, Feb-23, Volume: 281, Issue:2

    Topics: Adenosine Triphosphate; Amiloride; Apoptosis; Bepridil; Bumetanide; Calcium; Carrier Proteins; DNA Fragmentation; Dose-Response Relationship, Drug; Furosemide; Glyburide; Hepatoblastoma; Humans; Pinacidil; Potassium; Potassium Channel Blockers; Potassium Channels; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Chloride Symporters; Time Factors; Tolbutamide; Tumor Cells, Cultured

2001
Na(+)/Ca(2+) exchanger in porcine oocytes.
    Biology of reproduction, 2002, Volume: 67, Issue:4

    Topics: Amiloride; Animals; Base Sequence; Bepridil; Calcium; Calcium Channel Blockers; Cell Membrane; Cloning, Molecular; Enzyme Inhibitors; Female; Fluorescent Dyes; Fura-2; Immunohistochemistry; Molecular Sequence Data; Oocytes; Ouabain; Pimozide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Swine; Verapamil

2002