bepridil and 4-aminopyridine

bepridil has been researched along with 4-aminopyridine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Sen, S; Sinha, N1
Kobayashi, S; Masuda, Y; Nakaya, H; Ogura, T; Reien, Y; Saito, T1
Hasegawa, A; Higaki, K; Hisatome, I; Ikeda, N; Kato, M; Kurata, Y; Li, P; Miake, J; Ninomiya, H; Notsu, T; Sakata, S; Shiota, G; Shirayoshi, Y; Suzuki, S; Yamamoto, K; Yoshida, A1

Other Studies

6 other study(ies) available for bepridil and 4-aminopyridine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Inhibitory effect of bepridil on hKv1.5 channel current: comparison with amiodarone and E-4031.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: 4-Aminopyridine; Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Function; Bepridil; Dose-Response Relationship, Drug; Gene Expression; Heart Atria; Humans; In Vitro Techniques; Kv1.5 Potassium Channel; Membrane Potentials; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Rats

2001
Stabilization of Kv1.5 channel protein by bepridil through its action as a chemical chaperone.
    European journal of pharmacology, 2012, Dec-05, Volume: 696, Issue:1-3

    Topics: 4-Aminopyridine; Animals; Bepridil; Chlorocebus aethiops; COS Cells; Endoplasmic Reticulum; Golgi Apparatus; Kv1.5 Potassium Channel; Membrane Transport Modulators; Potassium Channel Blockers; Rats

2012